New arylalkanones from Horsfieldia macrobotrys, effective antidiabetic agents concomitantly inhibiting α-glucosidase and free radicals

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 20, 2015, Pages 4529-4533

  Ramadhan, Rico ^a,b   Phuwapraisirisan, Preecha ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b MULAWARMAN UNIVERSITY   (Indonesia)

Author keywords

Antioxidant; Arylalkanone; Diabetes; Glucosidase; Horsfieldia macrobotrys; Myristica motley

Indexed keywords

8 C BETA DEXTRO GLUCOPYRANOSYLPINOCEMBRIN; ALPHA GLUCOSIDASE; ANTIDIABETIC AGENT; ARYLALKANONE; FREE RADICAL; HORSFIELDONE; MAINGAYONE; SUCRASE; UNCLASSIFIED DRUG; GLYCOSIDASE INHIBITOR; KETONE; SCAVENGER;

ANIMAL EXPERIMENT; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BARK; COLUMN CHROMATOGRAPHY; DISSOCIATION CONSTANT; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HORSFIELDIA MACROBOTRYS; IC50; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STEREOCHEMISTRY; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ISOLATION AND PURIFICATION; METABOLISM; MYRISTICACEAE; STRUCTURE ACTIVITY RELATION;

ALPHA-GLUCOSIDASES; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; FREE RADICALS; GLYCOSIDE HYDROLASE INHIBITORS; HYPOGLYCEMIC AGENTS; KETONES; MOLECULAR STRUCTURE; MYRISTICACEAE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84942825826     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.08.069     Document Type: Article

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