-
1
-
-
33645757920
-
Definition, evaluation, and classification of renal osteodystrophy: A position statement from kidney disease: Improving global outcomes (KDIGO)
-
Moe S, Drueke T, Cunningham J, et al. Definition, evaluation, and classification of renal osteodystrophy: a position statement from kidney disease: improving global outcomes (KDIGO). Kidney Int 2006;69:1945-1953.
-
(2006)
Kidney Int
, vol.69
, pp. 1945-1953
-
-
Moe, S.1
Drueke, T.2
Cunningham, J.3
-
2
-
-
79955567444
-
Secondary hyperparathyroidism: Pathogenesis, disease progression, and therapeutic options
-
Cunningham J, Locatelli F, Rodriguez M. Secondary hyperparathyroidism: pathogenesis, disease progression, and therapeutic options. Clin J Am Soc Nephrol 2011;6:913-921.
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 913-921
-
-
Cunningham, J.1
Locatelli, F.2
Rodriguez, M.3
-
3
-
-
81755165861
-
CKD-mineral and bone disorder: Core curriculum 2011
-
Moorthi RN, Moe SM. CKD-mineral and bone disorder: core curriculum 2011. Am J Kidney Dis 2011;58:1022-1036.
-
(2011)
Am J Kidney Dis
, vol.58
, pp. 1022-1036
-
-
Moorthi, R.N.1
Moe, S.M.2
-
4
-
-
68949114585
-
KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD)
-
Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD). Kidney Int 2009;76(Suppl 113):S1-S130.
-
(2009)
Kidney Int
, vol.76
, pp. S1-S130
-
-
-
5
-
-
84885664875
-
Sclerostin: Another bone-related protein related to all-cause mortality in haemodialysis?
-
Viaene L, Behets GJ, Claes K, et al. Sclerostin: another bone-related protein related to all-cause mortality in haemodialysis? Nephrol Dial Transplant 2013;28:3024-3030.
-
(2013)
Nephrol Dial Transplant
, vol.28
, pp. 3024-3030
-
-
Viaene, L.1
Behets, G.J.2
Claes, K.3
-
6
-
-
84865276585
-
Arterial calcification and bone physiology: Role of the bone-vascular axis
-
Thompson B, Towler DA. Arterial calcification and bone physiology: role of the bone-vascular axis. Nat Rev Endocrinol 2012;8:529-543.
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 529-543
-
-
Thompson, B.1
Towler, D.A.2
-
7
-
-
84887850216
-
Sclerostin as a potential novel biomarker for aortic valve calcification: An in-vivo and ex-vivo study
-
Koos R, Brandenburg V, Mahnken AH, et al. Sclerostin as a potential novel biomarker for aortic valve calcification: an in-vivo and ex-vivo study. J Heart Valve Dis 2013;22:317-325.
-
(2013)
J Heart Valve Dis
, vol.22
, pp. 317-325
-
-
Koos, R.1
Brandenburg, V.2
Mahnken, A.H.3
-
8
-
-
84926162523
-
Vascular calcification and renal bone disorders
-
Lu KC, Wu CC, Yen JF, Liu WC. Vascular calcification and renal bone disorders. ScientificWorldJournal 2014;2014:637065. doi: 10.1155/2014/637065.
-
(2014)
ScientificWorldJournal
, vol.2014
, pp. 637065
-
-
Lu, K.C.1
Wu, C.C.2
Yen, J.F.3
Liu, W.C.4
-
9
-
-
84898753597
-
Update on romosozumab: A humanized monoclonal antibody to sclerostin
-
Costa AG, Bilezikian JP, Lewiecki EM. Update on romosozumab: a humanized monoclonal antibody to sclerostin. Expert Opin Biol Ther 2014;14:697-707.
-
(2014)
Expert Opin Biol Ther
, vol.14
, pp. 697-707
-
-
Costa, A.G.1
Bilezikian, J.P.2
Lewiecki, E.M.3
-
10
-
-
12144286871
-
Sclerostin is an osteocyteexpressed negative regulator of bone formation, but not a classical BMP antagonist
-
Van Bezooijen RL, Roelen BA, Visser A, et al. Sclerostin is an osteocyteexpressed negative regulator of bone formation, but not a classical BMP antagonist. J Exp Med 2004;199:805-814.
-
(2004)
J Exp Med
, vol.199
, pp. 805-814
-
-
Van Bezooijen, R.L.1
Roelen, B.A.2
Visser, A.3
-
11
-
-
78650646959
-
Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways
-
Krause C, Korchynskyi O, De Rooij K, et al. Distinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathways. J Biol Chem 2010;285:41614-41626.
-
(2010)
J Biol Chem
, vol.285
, pp. 41614-41626
-
-
Krause, C.1
Korchynskyi, O.2
De Rooij, K.3
-
12
-
-
21244480924
-
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
-
Li X, Zhang Y, Kang H, et al. Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem 2005;280:19883-19887.
-
(2005)
J Biol Chem
, vol.280
, pp. 19883-19887
-
-
Li, X.1
Zhang, Y.2
Kang, H.3
-
13
-
-
22844445934
-
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
-
Semenov M, Tamai K, He X. SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. J Biol Chem 2005;280:26770-26775.
-
(2005)
J Biol Chem
, vol.280
, pp. 26770-26775
-
-
Semenov, M.1
Tamai, K.2
He, X.3
-
14
-
-
33845927993
-
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
-
Van Bezooijen RL, Svensson JP, Eefting D, et al. Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. J Bone Miner Res 2007;22:19-28.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 19-28
-
-
Van Bezooijen, R.L.1
Svensson, J.P.2
Eefting, D.3
-
15
-
-
34249978979
-
The Wnt signaling pathway and bone metabolism
-
Johnson ML, Kamel MA. The Wnt signaling pathway and bone metabolism. Curr Opin Rheumatol 2007;19:376-382.
-
(2007)
Curr Opin Rheumatol
, vol.19
, pp. 376-382
-
-
Johnson, M.L.1
Kamel, M.A.2
-
16
-
-
28744432803
-
Bone mineral density in sclerosteosis; affected individuals and gene carriers
-
Gardner JC, Van Bezooijen RL, Mervis B, et al. Bone mineral density in sclerosteosis; affected individuals and gene carriers. J Clin Endocrinol Metab 2005;90:6392-6395.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 6392-6395
-
-
Gardner, J.C.1
Van Bezooijen, R.L.2
Mervis, B.3
-
17
-
-
81855180504
-
Patients with sclerosteosis and disease carriers: Human models of the effect of sclerostin on bone turnover
-
Van Lierop AH, Hamdy NA, Hamersma H, et al. Patients with sclerosteosis and disease carriers: human models of the effect of sclerostin on bone turnover. J Bone Miner Res 2011;26:2804-2811.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 2804-2811
-
-
Van Lierop, A.H.1
Hamdy, N.A.2
Hamersma, H.3
-
18
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
Li X, Ominsky MS, Niu QT, et al. Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res 2008;23:860-869.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.T.3
-
19
-
-
84899651287
-
Comparison of two commercially available ELISAs for circulating sclerostin
-
Costa AG, Cremers S, Dworakowski E, et al. Comparison of two commercially available ELISAs for circulating sclerostin. Osteoporos Int 2014;25:1547-1554.
-
(2014)
Osteoporos Int
, vol.25
, pp. 1547-1554
-
-
Costa, A.G.1
Cremers, S.2
Dworakowski, E.3
-
20
-
-
77957853500
-
Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women
-
Drake MT, Srinivasan B, Modder UI, et al. Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab 2010;95:5056-5062.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 5056-5062
-
-
Drake, M.T.1
Srinivasan, B.2
Modder, U.I.3
-
21
-
-
84877641819
-
The relation between renal function and serum sclerostin inadult patients with CKD
-
Pelletier S, Dubourg L, Carlier MC, et al. The relation between renal function and serum sclerostin inadult patients with CKD. Clin J AmSoc Nephrol 2013;8:819-823.
-
(2013)
Clin J AmSoc Nephrol
, vol.8
, pp. 819-823
-
-
Pelletier, S.1
Dubourg, L.2
Carlier, M.C.3
-
23
-
-
84922803328
-
Uremic toxicity and sclerostin in chronic kidney disease patients
-
Desjardins L, Liabeuf S, Oliveira RB, et al. Uremic toxicity and sclerostin in chronic kidney disease patients. Nephrol Ther 2014;10:463-470.
-
(2014)
Nephrol Ther
, vol.10
, pp. 463-470
-
-
Desjardins, L.1
Liabeuf, S.2
Oliveira, R.B.3
-
24
-
-
84892181516
-
Renal elimination of sclerostin increases with declining kidney function
-
Cejka D, Marculescu R, Kozakowski N, et al. Renal elimination of sclerostin increases with declining kidney function. J Clin Endocrinol Metab 2014;99:248-255.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. 248-255
-
-
Cejka, D.1
Marculescu, R.2
Kozakowski, N.3
-
25
-
-
84906035179
-
Sclerostin blood levels before and after kidney transplantation
-
Bonani M, Rodriguez D, Fehr T, et al. Sclerostin blood levels before and after kidney transplantation. Kidney Blood Press Res 2014;39:230-239.
-
(2014)
Kidney Blood Press Res
, vol.39
, pp. 230-239
-
-
Bonani, M.1
Rodriguez, D.2
Fehr, T.3
-
26
-
-
84889776955
-
Circulating sclerostin levels and markers of bone turnover in Chinese-American and white women
-
Costa AG, Walker MD, Zhang CA, et al. Circulating sclerostin levels and markers of bone turnover in Chinese-American and white women. J Clin Endocrinol Metab 2013;98:4736-4743.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 4736-4743
-
-
Costa, A.G.1
Walker, M.D.2
Zhang, C.A.3
-
27
-
-
84875129644
-
Serum sclerostin levels in men with idiopathic osteoporosis
-
Lapauw B, Vandewalle S, Taes Y, et al. Serum sclerostin levels in men with idiopathic osteoporosis. Eur J Endocrinol 2013;168:615-620.
-
(2013)
Eur J Endocrinol
, vol.168
, pp. 615-620
-
-
Lapauw, B.1
Vandewalle, S.2
Taes, Y.3
-
28
-
-
84910017231
-
Relationship between serum sclerostin, bone metabolism markers, and bone mineral density in maintenance hemodialysis patients
-
Ishimura E, Okuno S, Ichii M, et al. Relationship between serum sclerostin, bone metabolism markers, and bone mineral density in maintenance hemodialysis patients. J Clin Endocrinol Metab 2014;99:4315-4320.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. 4315-4320
-
-
Ishimura, E.1
Okuno, S.2
Ichii, M.3
-
31
-
-
84907647155
-
Serum sclerostin and adverse outcomes in nondialyzed chronic kidney disease patients
-
Kanbay M, Siriopol D, Saglam M, et al. Serum sclerostin and adverse outcomes in nondialyzed chronic kidney disease patients. J Clin Endocrinol Metab 2014;99:E1854-E1861. First study to study to show the association between sclerostin and all causes of mortality and cardiovascular events in CKD patients.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. E1854-E1861
-
-
Kanbay, M.1
Siriopol, D.2
Saglam, M.3
-
32
-
-
54249123586
-
Bone markers predict cardiovascular events in chronic kidney disease
-
Fahrleitner-Pammer A, Herberth J, Browning SR, et al. Bone markers predict cardiovascular events in chronic kidney disease. J Bone Miner Res 2008;23:1850-1858.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 1850-1858
-
-
Fahrleitner-Pammer, A.1
Herberth, J.2
Browning, S.R.3
-
33
-
-
84922549146
-
High levels of circulating sclerostin are associated with better cardiovascular survival in incident dialysis patients: Results from the NECOSAD study
-
Drechsler C, Evenepoel P, Vervloet MG, et al. High levels of circulating sclerostin are associated with better cardiovascular survival in incident dialysis patients: results from the NECOSAD study. Nephrol Dial Transplant 2015;30:288-293. doi: 10.1093/ndt/gfu301.
-
(2015)
Nephrol Dial Transplant
, vol.30
, pp. 288-293
-
-
Drechsler, C.1
Evenepoel, P.2
Vervloet, M.G.3
-
34
-
-
78650958526
-
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
-
Padhi D, Jang G, Stouch B, et al. Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 2011;26:19-26.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 19-26
-
-
Padhi, D.1
Jang, G.2
Stouch, B.3
-
35
-
-
84894866129
-
Multiple doses of sclerostin antibody romosozumab in healthy men and postmenopausal women with low bone mass: A randomized, double-blind, placebo-controlled study
-
Padhi D, Allison M, Kivitz AJ, et al. Multiple doses of sclerostin antibody romosozumab in healthy men and postmenopausal women with low bone mass: A randomized, double-blind, placebo-controlled study. J Clin Pharmacol 2014;54:168-178. doi: 10.1002/jcph.239.
-
(2014)
J Clin Pharmacol
, vol.54
, pp. 168-178
-
-
Padhi, D.1
Allison, M.2
Kivitz, A.J.3
-
36
-
-
84942789240
-
Effects of romosozumab administration on trabecular and cortical bone assessed with quantitative computed tomography and finite element analysis
-
Lisbon, Portugal. Bone Abstracts 1 OC5.4
-
Graeff C, Campbell G, Peña J, et al. Effects of romosozumab administration on trabecular and cortical bone assessed with quantitative computed tomography and finite element analysis. Presented at the European Calcified Tissue Society Conference ECTS 18-21 May 2013, Lisbon, Portugal. Bone Abstracts 1 OC5.4. doi: 10.1530/boneabs.01. OC5.4.
-
The European Calcified Tissue Society Conference ECTS 18-21 May 2013
-
-
Graeff, C.1
Campbell, G.2
Peña, J.3
-
37
-
-
84893044528
-
Romosozumab in postmenopausal & women with low bone mineral density
-
McClung MR, Grauer A, Boonen S, et al. Romosozumab in postmenopausal & women with low bone mineral density. N Engl J Med 2014;370:412-420. Phase II trial of romosozumab, a humanized sclerostin antibody.
-
(2014)
N Engl J Med
, vol.370
, pp. 412-420
-
-
McClung, M.R.1
Grauer, A.2
Boonen, S.3
-
38
-
-
84897586287
-
Single- and multiple-dose randomized studies of blosozumab, a monoclonal antibody against sclerostin, in healthy postmenopausal women
-
2
-
McColm J, Hu L, Womack T, et al. Single- and multiple-dose randomized studies of blosozumab, a monoclonal antibody against sclerostin, in healthy postmenopausal women. J Bone Miner Res 2014;29:935-943. doi: 2.
-
(2014)
J Bone Miner Res
, vol.29
, pp. 935-943
-
-
McColm, J.1
Hu, L.2
Womack, T.3
-
39
-
-
84921809759
-
A randomized, double-blind phase 2 & clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density
-
Recker R, Benson C, Matsumoto T, et al. A randomized, double-blind phase 2 & clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density. J Bone Min Res 2015;30:216-224. doi: 10.1002/jbmr.2351. Data of phase 2 trial of blosozumab, a humanized sclerostin antibody.
-
(2015)
J Bone Min Res
, vol.30
, pp. 216-224
-
-
Recker, R.1
Benson, C.2
Matsumoto, T.3
-
40
-
-
84922932317
-
Anti-sclerostin antibody treatment in a & rat model of progressive renal osteodystrophy
-
Moe SM, Chen NX, Newman CL, et al. Anti-sclerostin antibody treatment in a & rat model of progressive renal osteodystrophy. J Bone Miner Res 2015;30:499-509. doi: 10.1002/jbmr.2372. Scl-Ab preclinical trial in a rat model of CKD-MB.
-
(2015)
J Bone Miner Res
, vol.30
, pp. 499-509
-
-
Moe, S.M.1
Chen, N.X.2
Newman, C.L.3
-
41
-
-
84899101265
-
CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder
-
Fang Y, Ginsberg C, Seifert M, et al. CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder. J Am Soc Nephrol 2014;25:1760-1773.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 1760-1773
-
-
Fang, Y.1
Ginsberg, C.2
Seifert, M.3
|