Pulmonary vascular response patterns during exercise in interstitial lung disease

European Respiratory Journal

Volumn 46, Issue 3, 2015, Pages 738-749

  Degani Costa, Luiza H ^a,b   Levarge, Barbara ^b   Digumarthy, Subba R ^c   Eisman, Aaron S ^c   Harris, R Scott ^b   Lewis, Gregory D ^b,c  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BODY MASS; CARDIOPULMONARY EXERCISE TEST; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EXERCISE; FEMALE; FIBROSING ALVEOLITIS; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; FUNCTIONAL STATUS; GAS EXCHANGE; HEART OUTPUT; HEMODYNAMIC MONITORING; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG ARTERY PRESSURE; MALE; OXYGEN CONSUMPTION; OXYGEN DESATURATION; PREDICTION; PRIORITY JOURNAL; PULMONARY VASCULAR DISEASE; AGE; ANAEROBIC THRESHOLD; CHI SQUARE DISTRIBUTION; COHORT ANALYSIS; COMPARATIVE STUDY; COMPLICATION; EXERCISE TEST; EXERCISE TOLERANCE; HEART STROKE VOLUME; LUNG FUNCTION TEST; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; PULMONARY HYPERTENSION; REFERENCE VALUE; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEX DIFFERENCE; STATISTICAL MODEL; VASCULAR RESISTANCE;

AGE FACTORS; AGED; ANAEROBIC THRESHOLD; CARDIAC OUTPUT; CHI-SQUARE DISTRIBUTION; COHORT STUDIES; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HUMANS; HYPERTENSION, PULMONARY; LINEAR MODELS; LOGISTIC MODELS; LUNG DISEASES, INTERSTITIAL; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REFERENCE VALUES; RESPIRATORY FUNCTION TESTS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEX FACTORS; STROKE VOLUME; VASCULAR RESISTANCE;

EID: 84942772938     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00191014     Document Type: Article

References (29)

1. Boutou AK, Pitsiou GG, Trigonis I, et al. Exercise capacity in idiopathic pulmonary fibrosis: the effect of pulmonary hypertension. Respirology 2011; 16: 451-458.
2. Naeije R, Vanderpool R, Dhakal BP, et al. Exercise-induced pulmonary hypertension. Am J Respir Crit Care Med 2013; 187: 576-583.
3. Lewis GD, Bossone E, Naeije R, et al. Pulmonary vascular hemodynamic response to exercise in cardiopulmonary diseases. Circulation 2013; 128: 1470-1479.
4. Lewis GD, Murphy RM, Shah RV, et al. Pulmonary vascular response patterns during exercise in left ventricular systolic dysfunction predict exercise capacity and outcomes. Circ Heart Fail 2011; 4: 276-285.
5. Tolle JJ, Waxman AB, Van Horn TL, et al. Exercise-induced pulmonary arterial hypertension. Circulation 2008; 118: 2183-2189.
6. Magne J, Lancellotti P, Pierard LA. Exercise pulmonary hypertension in asymptomatic degenerative mitral regurgitation. Circulation 2010; 122: 33-41.
7. Lancellotti P, Magne J, Donal E, et al. Determinants and prognostic significance of exercise pulmonary hypertension in asymptomatic severe aortic stenosis. Circulation 2012; 126: 851-859.
8. Kessler R, Faller M, Weitzenblum E, et al. "Natural history" of pulmonary hypertension in a series of 131 patients with chronic obstructive lung disease. Am J Respir Crit Care Med 2001; 164: 219-224.
9. Condliffe R, Kiely DG, Peacock AJ, et al. Connective tissue disease-associated pulmonary arterial hypertension in the modern treatment era. Am J Respir Crit Care Med 2009; 179: 151-157.
10. Lettieri CJ, Nathan SD, Barnett SD, et al. Prevalence and outcomes of pulmonary arterial hypertension in idiopathic pulmonary fibrosis. Chest 2006; 129: 746-752.
11. Nadrous HF, Pellikka PA, Krowka MJ, et al. Pulmonary hypertension in patients with idiopathic pulmonary fibrosis. Chest 2005; 128: 2393-2399.
12. Patel NM, Lederer DJ, Borczuk AC, et al. Pulmonary hypertension in idiopathic pulmonary fibrosis. Chest 2007; 132: 998-1006.
13. Kimura M, Taniguchi H, Kondoh T, et al. Pulmonary hypertension as a prognostic indicator at the initial evaluation in idiopathic pulmonary fibrosis. Respiration 2013; 85: 456-463.
14. Launay D, Mouthon L, Hachulla E, et al. Prevalence and characteristics of moderate to severe pulmonary hypertension in systemic sclerosis with and without interstitial lung disease. J Rheumatol 2007; 34: 1005-1011.
15. Shorr AF, Helman DL, Davies DB, et al. Pulmonary hypertension in advanced sarcoidosis: epidemiology and clinical characteristics. Eur Respir J 2005; 25: 783-788.
16. Hoeper MM, Bogaard HJ, Condliffe R, et al. Definitions and diagnosis of pulmonary hypertension. J Am Coll Cardiol 2013; 62: D42-D50.
17. Poon CS. Analysis of linear and mildly nonlinear relationships using pooled subject data. J Appl Physiol 1988; 64: 854-859.
18. Andersen CU, Mellemkjaer S, Hilberg O, et al. Pulmonary hypertension in interstitial lung disease: prevalence, prognosis and 6 min walk test. Respir Med 2012; 106: 875-882.
19. Armstrong HF, Thirapatarapong W, Dussault NE, et al. Distinguishing pulmonary hypertension in interstitial lung disease by ventilation and perfusion defects measured by cardiopulmonary exercise testing. Respiration 2013; 86: 407-413.
20. Nadrous HF, Pellikka PA, Krowka MJ, et al. The impact of pulmonary hypertension on survival in patients with idiopathic pulmonary fibrosis. Chest 2005; 128: 616S-617S.
21. Caminati A, Cassandro R, Harari S. Pulmonary hypertension in chronic interstitial lung diseases. Eur Respir Rev 2013; 22: 292-301.
22. Badesh DB, Champion HC, Sanchez MAG, et al. Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol 2009; 54: S55-S66.
23. Lewis GD. Pulmonary vascular response patterns to exercise: is there a role for pulmonary arterial pressure assessment during exercise in the post-Dana era? Adv Pulm Hypertens 2010; 9: 92-100.
24. Argiento P, Vanderpool RR, Mule M, et al. Exercise stress echocardiography of the pulmonary circulation: limits of normal and sex differences. Chest 2012; 142: 1158-1165.
25. Champion HC, Michelakis ED, Hassoun PM. Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications. Circulation 2009; 120: 992-1007.
26. Boerrigter BG, Waxman AB, Westerhof N, et al. Measuring central pulmonary pressures during exercise in COPD: how to cope with respiratory effects. Eur Respir J 2014; 43: 1316-1325.
27. Gargani L, Pignone A, Agoston G, et al. Clinical and echocardiographic correlations of exercise-induced pulmonary hypertension in systemic sclerosis: a multicenter study. Am Heart J 2013; 165: 200-207.
28. Saggar R, Lewis GD, Systrom DM, et al. Pulmonary vascular responses to exercise: a haemodynamic observation. Eur Respir J 2012; 39: 231-234.
29. Saggar R, Khanna D, Furst DE, et al. Exercise-induce pulmonary hypertension associated with systemic sclerosis. Four distinct entities. Arthritis Rheum 2010; 62: 3741-3750.