Low level engraftment and improvement following a single colonoscopic administration of fecal microbiota to patients with ulcerative colitis

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Damman, Christopher J ^a   Brittnacher, Mitchell J ^b   Westerhoff, Maria ^b   Hayden, Hillary S ^b   Radey, Matthew ^b   Hager, Kyle R ^b   Marquis, Sara R ^a   Miller, Samuel I ^b   Zisman, Timothy L ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN;

ABDOMINAL CRAMP; ABDOMINAL PAIN; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; COLONIC SECRETION; COLONOSCOPY; DONOR SELECTION; FECAL MICROBIOTA TRANSPLANTATION; FECES ANALYSIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTERVENTION STUDY; INTESTINE TRANSIT TIME; MALE; MIDDLE AGED; OPEN STUDY; OUTCOME ASSESSMENT; PATIENT SAFETY; PHYLOGENY; PILOT STUDY; PROSPECTIVE STUDY; REMISSION; TRANSPLANTATION; ULCERATIVE COLITIS; COLITIS, ULCERATIVE; COLON; FECES; MICROBIOLOGY; MICROFLORA; PATHOLOGY; PROCEDURES; TREATMENT OUTCOME;

ADULT; COLITIS, ULCERATIVE; COLON; COLONOSCOPY; FECES; FEMALE; HUMANS; MALE; MICROBIOTA; MIDDLE AGED; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84942673401     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133925     Document Type: Article

References (34)

1. Kappelman MD, Rifas-Shiman SL, Kleinman K, Ollendorf D, Bousvaros A, Grand RJ, et al. The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol. 2007; 5: 1424-9. doi: 10.1016/j.cgh.2007.07.012 PMID: 17904915
2. Talley NJ, Abreu MT, Achkar J-P, Bernstein CN, Dubinsky MC, Hanauer SB, et al. An evidence-based systematic review on medical therapies for inflammatory bowel disease. Am J Gastroenterol. Nature Publishing Group; 2011; 106 Suppl: S2-25; quiz S26. doi: 10.1038/ajg.2011.58
3. Cima RR. Timing and indications for colectomy in chronic ulcerative colitis: Surgical consideration. Dig Dis. 2010; 28: 501-7. doi: 10.1159/000320409 PMID: 20926879
4. Nagalingam N a, Lynch S V. Role of the microbiota in inflammatory bowel diseases. Inflamm Bowel Dis. 2011; 1-13. doi: 10.1002/ibd.21866
5. Michail S, Durbin M, Turner D, Griffiths AM, Mack DR, Hyams J, et al. Alterations in the gut microbiome of children with severe ulcerative colitis. Inflamm Bowel Dis. 2012; 18: 1799-808. doi: 10.1002/ibd. 22860 PMID: 22170749
6. Rajilic-Stojanovic M, Shanahan F, Guarner F, de Vos WM. Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission. Inflamm Bowel Dis. 2013;0: 1-8. doi: 10.1097/MIB.0b013e31827fec6d
7. Khan KJ, Ullman T a, Ford AC, Abreu MT, Abadir A, Abadir a, et al. Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis. Am J Gastroenterol. 2011; 106: 661-73. doi: 10.1038/ajg.2011.72 PMID: 21407187
8. Meijer BJ, Dieleman LA. Probiotics in the treatment of human inflammatory bowel diseases: update 2011. J Clin Gastroenterol. 2011; 45 Suppl: S139-44. doi: 10.1097/MCG.0b013e31822103f7 PMID: 21992953
9. Bakken JS, Borody T, Brandt LJ, Brill J V, Demarco DC, Franzos MA, et al. Treating Clostridium difficile infection with fecal microbiota transplantation. Clin Gastroenterol Hepatol. Elsevier Inc.; 2011; 9: 1044-9. doi: 10.1016/j.cgh.2011.08.014 PMID: 21871249
10. Van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, Zoetendal EG, de Vos WM, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med. 2013; 368: 407-15. doi: 10.1056/NEJMoa1205037 PMID: 23323867
11. Damman CJ, Miller SI, Surawicz CM, Zisman TL. The Microbiome and Inflammatory Bowel Disease: Is There a Therapeutic Role for Fecal Microbiota Transplantation? Am J Gastroenterol. 2012; 107: 1452-1459. doi: 10.1038/ajg.2012.93 PMID: 23034604
12. Anderson JL, Edney RJ, Whelan K. Systematic review: faecal microbiota transplantation in the management of inflammatory bowel disease. Aliment Pharmacol Ther. 2012; 36: 503-16. doi: 10.1111/j. 1365-2036.2012.05220.x PMID: 22827693
13. Bennet J, Brinkman M, others. Treatment of ulcerative colitis by implantation of normal colonic flora. Lancet. 1989; 1: 164. Available: http://www.ncbi.nlm.nih.gov/pubmed/2563083
14. Borody T, George L, Andrews P, Brandl S, Noonan S, Cole P, et al. Bowel-flora alteration: a potential cure for inflammatory bowel disease and irritable bowel syndrome? Med J Aust. 1989; 150: 604. Available: http://www.ncbi.nlm.nih.gov/pubmed/2783214
15. Borody TJ, Warren EF, Leis S, Surace R, Ashman O. Treatment of ulcerative colitis using fecal bacteriotherapy. J Clin Gastroenterol. 2003; 37: 42-7. Available: http://www.ncbi.nlm.nih.gov/pubmed/12811208 PMID: 12811208
16. Moayyedi P, Surette MG, Kim PT, Libertucci J, Wolfe M, Onischi C, et al. Fecal Microbiota Transplantation Induces Remission in Patients with Active Ulcerative Colitis in a Randomized, Controlled Trial. Gastroenterology. Elsevier, Inc; 2015; 149: 102-109.e6. doi: 10.1053/j.gastro.2015.04.001 PMID: 25857665
17. Rossen NG, Fuentes S, van der Spek MJ, Tijssen J, Hartman JH a., Duflou A, et al. Findings from a Randomized Controlled Trial of Fecal Transplantation for Patients with Ulcerative Colitis. Gastroenterology. 2015; 110-118. doi: 10.1053/j.gastro.2015.03.045 PMID: 25836986
18. Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med. 1987; 317: 1625-9. doi: 10.1056/NEJM198712243172603 PMID: 3317057
19. Maillet N, Lemaitre C, Chikhi R, Lavenier D, Peterlongo P. Compareads: comparing huge metagenomic experiments. BMC Bioinformatics. BioMed Central Ltd; 2012; 13 Suppl 1: S10. doi: 10.1186/1471-2105-13-S19-S10 PMID: 23282463
20. Lewis JD, Chuai S, Nessel L, Lichtenstein GR, Aberra FN, Ellenberg JH. Use of the noninvasive components of the Mayo score to assess clinical response in ulcerative colitis. Inflamm Bowel Dis. 2008; 14: 1660-6. doi: 10.1002/ibd.20520 PMID: 18623174
21. Swidsinski A, Loening-Baucke V, Verstraelen H, Osowska S, Doerffel Y. Biostructure of fecal microbiota in healthy subjects and patients with chronic idiopathic diarrhea. Gastroenterology. 2008; 135: 568-79. doi: 10.1053/j.gastro.2008.04.017 PMID: 18570896
22. Rotmistrovsky KAR. BMTagger: Best Match Tagger for removing human reads from metagenomics datasets. Unpublished. 2011;
23. Segata N, Waldron L, Ballarini A, Narasimhan V, Jousson O, Huttenhower C. Metagenomic microbial community profiling using unique clade-specific marker genes. Nat Methods. 2012; 9: 811-4. doi: 10. 1038/nmeth.2066 PMID: 22688413
24. Shannon CE. A mathematical theory of communication. Bell Syst Tech J. 1948; 27: 379-423; 623-656.
25. Song Y, Könönen E, Rautio M, Liu C, Bryk A, Eerola E, et al. Alistipes onderdonkii sp. nov. and Alistipes shahii sp. nov., of human origin. Int J Syst Evol Microbiol. 2006; 56: 1985-90. doi: 10.1099/ijs.0.64318-0 PMID: 16902041
26. Feces H, Johnson JL, Moore WEC, Moore LVH. Bacteroides caccae. 1986; 499-501.
27. Würdemann D, Tindall BJ, Pukall R, Lünsdorf H, Strömpl C, Namuth T, et al. Gordonibacter pamelaeae gen. nov., sp. nov., a new member of the Coriobacteriaceae isolated from a patient with Crohn's disease, and reclassification of Eggerthella hongkongensis Lau et al. 2006 as Paraeggerthella hongkongensis gen. nov., comb. nov. Int J Syst Evol Microbiol. 2009; 59: 1405-15. doi: 10.1099/ijs.0.005900-0 PMID: 19502325
28. Woo PCY, Teng JLL, Lam KKM, Tse CWS, Leung K-W, Leung AWS, et al. First report of Gordonibacter pamelaeae bacteremia. J Clin Microbiol. 2010; 48: 319-22. doi: 10.1128/JCM.01459-09 PMID: 19923481
29. Kunde S, Pham A, Bonczyk S, Crumb T, Duba M, Conrad H, et al. Safety, tolerability, and clinical response after fecal transplantation in children and young adults with ulcerative colitis. J Pediatr Gastroenterol Nutr. 2013; 56: 597-601. doi: 10.1097/MPG.0b013e318292fa0d PMID: 23542823
30. Angelberger S, Reinisch W, Makristathis A, Lichtenberger C, Dejaco C, Papay P, et al. Temporal bacterial community dynamics vary among ulcerative colitis patients after fecal microbiota transplantation. Am J Gastroenterol. 2013; 108: 1620-30. doi: 10.1038/ajg.2013.257 PMID: 24060759
31. Kump PK, Gröchenig H-P, Lackner S, Trajanoski S, Reicht G, Hoffmann KM, et al. Alteration of Intestinal Dysbiosis by Fecal Microbiota Transplantation Does not Induce Remission in Patients with Chronic Active Ulcerative Colitis. Inflamm Bowel Dis. 2013; 19: 2155-2165. doi: 10.1097/MIB. 0b013e31829ea325 PMID: 23899544
32. Alpert C, Sczesny S, Gruhl B, Blaut M. Long-term stability of the human gut microbiota in two different rat strains. Curr Issues Mol Biol. 2008; 10: 17-24. Available: http://www.ncbi.nlm.nih.gov/pubmed/18525103 PMID: 18525103
33. Khoruts A, Dicksved J, Jansson JK, Sadowsky MJ. Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-associated diarrhea. J Clin Gastroenterol. 2010; 44: 354-60. doi: 10.1097/MCG.0b013e3181c87e02 PMID: 20048681
34. Borody TJ, Khoruts A. Fecal microbiota transplantation and emerging applications. Nat Rev Gastroenterol Hepatol. Nature Publishing Group; 2012; 9: 88-96. doi: 10.1038/nrgastro.2011.244