Preventing heart failure: The role of physical activity

Current Opinion in Cardiology

Volumn 30, Issue 5, 2015, Pages 543-550

  Nayor, Matthew ^a,b   Vasan, Ramachandran S ^a,c,d  

^a FRAMINGHAM HEART STUDY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Exercise; Heart failure; Physical activity; Prevention; Remodeling

Indexed keywords

AEROBIC EXERCISE; ARTERIAL STIFFNESS; CARDIORESPIRATORY FITNESS; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE COURSE; HEART FAILURE; HEART LEFT VENTRICLE MASS; HEART RIGHT VENTRICLE ENDDIASTOLIC VOLUME; HEART STROKE VOLUME; HUMAN; HYPERTENSION; INCIDENCE; KIDNEY FUNCTION; LUNG FUNCTION; NONHUMAN; OBESITY; PARASYMPATHETIC TONE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; QUESTIONNAIRE; REVIEW; RISK FACTOR; SMOKING; SYMPATHETIC TONE; AGING; EXERCISE TOLERANCE; HEALTH PROMOTION; HEART VENTRICLE REMODELING; KINESIOTHERAPY; MOTOR ACTIVITY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; PSYCHOLOGY; RISK REDUCTION; SEDENTARY LIFESTYLE;

AGING; EXERCISE THERAPY; EXERCISE TOLERANCE; HEALTH PROMOTION; HEART FAILURE; HUMANS; MOTOR ACTIVITY; RISK REDUCTION BEHAVIOR; SEDENTARY LIFESTYLE; STROKE VOLUME; VENTRICULAR REMODELING;

EID: 84942587923     PISSN: 02684705     EISSN: 15317080     Source Type: Journal    
DOI: 10.1097/HCO.0000000000000206     Document Type: Review

References (50)

1. Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics-2015 update: a report from the American Heart Association. Circulation 2015; 131:e29-e322.
2. Dunlay SM,Roger VL. Understanding the epidemic of heart failure: past, present, and future Curr Heart Fail Rep 2014 11 404-415.
3. Luscher TF. Heart failure: the cardiovascular epidemic of the 21st century. Eur Heart J 2015; 36:395-397.
4. Eckel RH, Jakicic JM, Ard JD, et al. 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of th e American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014; 63:2960-2984.
5. Yancy CW, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA guidel ine for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2013; 62:e147-e239.
6. Baggish A L, Wood MJ. Athlete's heart and cardiovascular care of the athlete: scientific and clinical update. Circulation 2011; 123:2723-2735.
7. Kannel WB, Sorlie P. Some health benefits of physical activity. The Framingham Study. Arch Intern Med 1979; 139:857-861.
8. Larson EB, Wang L, Bowen JD, et al. Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Ann Intern Med 2006; 144:73-81.
9. Fried LP, Kronmal RA, Newman AB, et al. Risk factors for 5-year mortality in older adults: the Cardiovascular Health Study. JAMA 1998; 279:585-592.
10. Pluim BM, Zwinderman AH, van der Laarse A, van der Wall EE. The athlete's heart. A meta-Analysis of cardiac structure and function. Circulation 2000; 101:336-344.
11. Djoussé L, Driver JA, Gaziano JM. Relation between modifiable lifestyle factors and lifetime risk of heart failure. JAMA 2009; 302:394-400.
12. Agha G, Loucks EB, Tinker LF, et al. Healthy lifestyle and decreasing risk of heart failure in women. J Am Coll Cardiol 2014; 64:1777-1785.
13. He J, Ogden LG, Bazzano LA, et al. Risk factors for congestive heart failure in US men and women: NHANES I epidemiologic follow-up study. Arch Intern Med 2001; 161:996-1002.
14. Young DR, Reynolds K, Sidell M, et al. Effects of physical activity and sedentar y time on the risk of heart failure. Circ Heart Fail 2014; 7:21-27. A large cohort study evaluating the associations of both physical activity and sedentary time with incident heart failure. This study showed that both less physical activity and more sedentary time contributed to increased risk of heart failure.
15. Kraigher-Krainer E, Lyass A, Massaro JM, et al. Association of physical activity and heart failure with preserved vs. reduced ejecti on fraction in the elderly: the Framingham Heart Study. Eur J Heart Fail 2013; 15:742-746.
16. Hu G, Jousilahti P, Antikainen R, et al. Joint effects of physical activity, body mass index, waist circumference, and waist-to-hip ratio on the risk of heart failure. Circulation 2010; 121:237-244 .
17. Farrell SW, Finley CE, Radford NB, Haskell WL. Cardiorespiratory fitness, body mass index, and heart failure mortality in men: Cooper Center Longitudinal Study. Circ Heart Fail 2013; 6:898-905.
18. Physical activity and cardiovascular health. NIH Consensus Development Panel on Physical Activity and Cardiovascular Health. JAMA 1996; 276:241-246.
19. Turkbey EB, Jorgensen NW, Johnson WC, et al. Physical activity and physiological cardiac remodelling in a community setting: the Multi-Ethnic Study of Atherosclerosis (MESA). Heart 2010; 96:42-48.
20. Andersson C, Lyass A , Larson MG, et al. Physical activity measured by accelerometry and its associations with cardiac structure and vascular function in young and middle-Aged adults. J Am Heart Assoc 2015; 4:e001528. These investigators used an objecti v e measure of physical activity (accelerometry) over the course of one week, and demonstrated direct associations of greater physical activity with LV mass and left atrial size, and an inverse association with vascular stiffness.
21. Brinker SK, Pandey A, Ayers CR, et al. Association of cardiorespiratory fitness with left ventricular remodeling and diastolic function: the Cooper Center Longitudinal Study. JACC Heart Fail 2014; 2:238-246. Cross-se ctional report of the association of higher cardiorespiratory fitness with greater physiologic cardiac remodeling in nonathletes.
22. Cheng S, Xanthakis V, Sullivan LM, et al. Correlates of echocardiographic indices o f cardiac remodeling over the adult life course: longitudinal observations from the Framingham Heart Study. Circulation 2010; 122:570-578.
23. Redfield MM, Jacobsen SJ, Borlaug BA, et al. Age-And gender-related ventricular-vascular stiffening: a community-based study. Circulation 2005; 112:2254-2262.
24. Arbab-Zadeh A, Dijk E, Prasad A, et al. Effect of aging and physical activity on left ventricular compliance. Circulation 2004; 110:1799-1805.
25. Bhella PS, Hastings JL, Fujimoto N, et al. Impact of lifelong exercise ' dose' on left ventricular compliance and distensibility. J Am Coll Cardiol 2014; 64:1257-1266. Cross-sectional associations of the 'dose' of physical activity achieved and cardiac structure and function in 102 healthy seniors. Committed exercisers and Masters athletes had healthy left vent ricular compliance as opposed to the increased ventricular stiffness observed in more sedentary groups.
26. Arbab-Zadeh A, Perhonen M, Howden E, et al. Cardiac remodeling in response to 1 year of intensive endurance training. Circulation 2014; 130:2152-2161.
27. Fujimoto N, Prasad A, Hastings JL, et al. Cardiovascular effects of 1 year of progressive and vigorous exercise training in previously sedentary individuals older than 65 years of age. Circulation 2010; 1 22:1797-1805.
28. O'Connor CM,Whellan DJ,Lee KL,et al. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial JAMA 2009 301: 1439-1450.
29. Flynn KE, Pina IL, Whellan DJ, et al. Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA 2009; 301:1451-1459.
30. Hambrecht R, Gielen S, Linke A, et al. Effects of exercise training on left ventricular function and periphera l resistance in patients with chronic heart failure: a randomized trial. JAMA 2000; 283:3095-3101.
31. Haykowsky MJ, Timmons MP, Kruger C, et al. Meta-Analysis of aerobic interval training on exe rcise capacity and systolic function in patients with heart failure and reduced ejection fractions. Am J Cardiol 2013; 111:1466-1469.
32. Edelmann F, Gelbrich G, Dungen HD, et al. Exercise train ing improves exercise capacity and diastolic function in patients with heart failure with preserved ejection fraction: results of the Ex-DHF (Exercise training in Diastolic Heart Failure) pilot study. J Am Coll Cardiol 2011; 58:1780-1791.
33. Pandey A,Parashar A,Kumbhani DJ,et al. Exercise training in patients with heart failure and preserved ejection fraction: meta-Analysis of randomized control trials Circ Heart Fail 2015 8 33-40. Meta-Analysis of the effects of exercise in 276 patients with HFPEF. Cardiorespiratory fitness and quality of life were improved without statistically significant changes in LV diastolic function or remodeling.
34. Giele n S, Schuler G, Adams V. Cardiovascular effects of exercise training: molecular mechanisms. Circulation 2010; 122:1221-1238.
35. Levine BD, Zuckerman JH, Pawelczyk JA. Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism for orthostatic intolerance. Circulation 1997; 96:517-525.
36. Ellison GM, Waring CD, Vicinanza C, Torella D. Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms. Heart 2012; 98:5-10. 37.
37. Wei X, Liu X, Rosenzweig A. What do we know about the cardiac benefits of exercise Trends Cardiovasc Me d 2014. [Epub ahead of print] An excellent review of molecular mechanisms underlying improved cardiac function with exercise, with a particular focus on cardiomyocyte proliferation.
38. Siu PM, Bryner RW, Martyn JK, Alway SE. Apoptotic adaptations from exercise training in skeletal and cardiac muscles. FASEB J 2004; 18:1150-1152.
39. Bostrom P, Mann N, Wu J, et al. C/EBPbeta controls exercise-induced cardiac growth and protects against pathological cardiac remodeling. Cell 2010; 143:1072-1083.
40. Miyachi M, Yazawa H, Furukawa M, et al. Exercise training alters left ventricular geometry a nd attenuates heart failure in dahl salt-sensitive hypertensive rats. Hypertension 2009; 53:701-707.
41. Sarma S, Carrick-Ranson G, Fujimoto N, et al. Effects of age and aerobic fitness on myocardial lipid content. Circ Cardiovasc Imaging 2013; 6:1048-1055.
42. Hidalgo C, Saripalli C, Granzier HL. Effect of exercise training on posttranslational and posttranscriptional regulation of titin s tiffness in striated muscle of wild type and IG KO mice. Arch Biochem Biophys 2014; 552-553:100-107.
43. Coats AJ, Adamopoulos S, Radaelli A, et al. Controlled trial of physical training i n chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function. Circulation 1992; 85:2119-2131.
44. Xu X, Wan W, Powers AS, et al. Effects of exercise training on cardiac function and myocardial remodeling in post myocardial infarction rats. J Mol Cell Cardiol 2008; 44:114-122.
45. Ho JE, Larson MG, Ghorbani A, et al. Long-term cardiovascular risks associated with an elevated heart rate: the Framingham Heart Study. J Am Heart Assoc 2014; 3:e000668.
46. Dhakal BP, Malhotra R, Murphy RM, et al. Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: the role of abnormal peripheral oxygen extraction. Circ Heart Fail 2015; 8:286-294.
47. Ventura-Clapier R. Exercise training, energy metabolism, and heart failure. Appl Physiol Nutr Metab 2009; 34:336-339.
48. Al Dandachi G, Londner C, Caumont-Prim A, et al. Ageing and endurance training effects on quantity and quality of pulmonary vascular bed in healthy men. Respir Res 2014; 15:8. Demonstration of cross-sectional associations between endurance sport participation and higher pulmonary vascula r compliance.
49. Hawkins MS, Sevick MA, Richardson CR, et al. Association between physical activity and kidney function: National Health and Nutrition Examination Survey. Med Sci Sports Exerc 2011; 43: 1457-1464.
50. Kokkinos P, Faselis C, Myers J, et al. Exercise capacity and risk of chronic kidney disease in US veterans: a cohort study. Mayo Clin Proc 2015; 90:461-468.