Mycolic acid-containing bacteria activate heterologous secondary metabolite expression in Streptomyces lividans

Journal of Antibiotics

Volumn 68, Issue 9, 2015, Pages 594-597

  Onaka, Hiroyasu ^a,b   Ozaki, Taro ^a   Mori, Yukiko ^b   Izawa, Masumi ^b   Hayashi, Shohei ^a   Asamizu, Shumpei ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MYCOLIC ACID; REBECCAMYCIN; STAUROSPORINE;

ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CELL INTERACTION; CORYNEBACTERIUM GLUTAMICUM; GENE CLUSTER; HETEROLOGOUS EXPRESSION; LECHEVALIERIA AEROCOLONIGENES; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHODOCOCCUS ERYTHROPOLIS; SECONDARY METABOLISM; STREPTOMYCES LIVIDANS; BACTERIUM; GENETICS; METABOLISM;

BACTERIA; MYCOLIC ACIDS; SECONDARY METABOLISM; STREPTOMYCES LIVIDANS;

EID: 84942581618     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2015.31     Document Type: Article

References (15)

1. Ikeda, H., Shin-ya, K. & Omura, S. Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters. J. Ind. Microbiol. Biotechnol. 41, 233-250 (2014).
2. Bertrand, S., Bohni, N., Schnee, S., Schumpp, O., Gindro, K. & Wolfender, J. L. Metabolite induction via microorganism co-culture: A potential way to enhance chemical diversity for drug discovery. Biotechnol. Adv. 32, 1180-1204 (2014).
3. Onaka, H., Mori, Y., Igarashi, Y. & Furumai, T. Mycolic acid-containing bacteria induce natural-product biosynthesis in Streptomyces species. Appl. Environ. Microbiol. 77, 400-406 (2011).
4. Marrakchi, H., Laneelle, M. A. & Daffe, M. Mycolic acids: structures, biosynthesis, and beyond. Chem. Biol. 21, 67-85 (2014).
5. Igarashi, Y. et al. Alchivemycin A, a bioactive polycyclic polyketide with an unprecedented skeleton from Streptomyces sp. Org. Lett. 12, 3402-3405 (2010).
6. Kim, Y., In, Y., Ishida, T., Onaka, H. & Igarashi, Y. Biosynthetic origin of alchivemycin A, a new polyketide from Streptomyces and absolute configuration of alchivemycin B. Org. Lett. 15, 3514-3517 (2013).
7. Hoshino, S., Zhang, L., Awakawa, T., Wakimoto, T., Onaka, H. & Abe, I. Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acidcontaining bacteria and Streptomyces cinnamoneus NBRC 13823. J. Antibiot. 68, 342-344 (2015).
8. Onaka, H., Nakaho, M., Hayashi, K., Igarashi, Y. & Furumai, T. Cloning and characterization of the goadsporin biosynthetic gene cluster from Streptomyces sp. TP-A0584. Microbiology 151, 3923-3933 (2005).
9. Onaka, H., Taniguchi, S., Igarashi, Y. & Furumai, T. Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans. J. Antibiot. (Tokyo) 55, 1063-1071 (2002).
10. Onaka, H., Taniguchi, S., Ikeda, H., Igarashi, Y. & Furumai, T. pTOYAMAcos, pTYM18, and pTYM19, actinomycete-Escherichia coli integrating vectors for heterologous gene expression. J. Antibiot. (Tokyo) 56, 950-956 (2003).
11. Arnison, P. G. et al. Ribosomally synthesized and post-Translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat. Prod. Rep. 30, 108-160 (2013).
12. Onaka, H., Tabata, H., Igarashi, Y., Sato, Y. & Furumai, T. Goadsporin, a chemical substance which promotes secondary metabolism and morphogenesis in streptomycetes. I. Purification and characterization. J. Antibiot. (Tokyo) 54, 1036-1044 (2001).
13. Onaka, H., Taniguchi, S., Igarashi, Y. & Furumai, T. Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243. Biosci. Biotechnol. Biochem. 67, 127-138 (2003).
14. Sanchez, C., Mendez, C. & Salas, J. A. Indolocarbazole natural products: occurrence, biosynthesis, and biological activity. Nat. Prod. Rep. 23, 1007-1045 (2006).
15. Nakano, H. & Omura, S. Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine. J. Antibiot. (Tokyo) 62, 17-26 (2009).