-
1
-
-
84878774249
-
The importance of molecular profiling in predicting response to epidermal growth factor receptor family inhibitors in non-smallcell lung cancer: focus on clinical trial results
-
Tsao AS, Papadimitrakopoulou V. The importance of molecular profiling in predicting response to epidermal growth factor receptor family inhibitors in non-smallcell lung cancer: focus on clinical trial results. Clin Lung Cancer 2013;14:311-21.
-
(2013)
Clin Lung Cancer
, vol.14
, pp. 311-321
-
-
Tsao, A.S.1
Papadimitrakopoulou, V.2
-
3
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 2006;441:424-30.
-
(2006)
Nature
, vol.441
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
5
-
-
40849094167
-
Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site
-
Platz A, Egyhazi S, Ringborg U, et al. Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site. Mol Oncol 2008;1:395-405.
-
(2008)
Mol Oncol
, vol.1
, pp. 395-405
-
-
Platz, A.1
Egyhazi, S.2
Ringborg, U.3
-
6
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002;417:949-54.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
7
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
Wan PT, Garnett MJ, Roe SM, et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 2004;116:855-67.
-
(2004)
Cell
, vol.116
, pp. 855-867
-
-
Wan, P.T.1
Garnett, M.J.2
Roe, S.M.3
-
8
-
-
33745590413
-
ERK MAP kinase in G cell cycle progression and cancer
-
Torii S, Yamamoto T, Tsuchiya Y, et al. ERK MAP kinase in G cell cycle progression and cancer. Cancer Sci 2006;97:697-702.
-
(2006)
Cancer Sci
, vol.97
, pp. 697-702
-
-
Torii, S.1
Yamamoto, T.2
Tsuchiya, Y.3
-
9
-
-
84864285704
-
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
-
Hauschild A, Grob JJ, Demidov LV, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 2012;380:358-65.
-
(2012)
Lancet
, vol.380
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
-
10
-
-
79551563284
-
International association for the study of lung cancer/American thoracic society/European respiratory society international multidisciplinary classification of lung adenocarcinoma
-
Travis WD, Brambilla E, Noguchi M, et al. International association for the study of lung cancer/American thoracic society/European respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011;6:244-85.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 244-285
-
-
Travis, W.D.1
Brambilla, E.2
Noguchi, M.3
-
11
-
-
33847293670
-
Highthroughput oncogene mutation profiling in human cancer
-
Thomas RK, Baker AC, Debiasi RM, et al. Highthroughput oncogene mutation profiling in human cancer. Nat Genet 2007;39:347-51.
-
(2007)
Nat Genet
, vol.39
, pp. 347-351
-
-
Thomas, R.K.1
Baker, A.C.2
Debiasi, R.M.3
-
12
-
-
70849116358
-
Profiling critical cancer gene mutations in clinical tumor samples
-
MacConaill LE, Campbell CD, Kehoe SM, et al. Profiling critical cancer gene mutations in clinical tumor samples. PLoS One 2009;4:e7887.
-
(2009)
PLoS One
, vol.4
-
-
MacConaill, L.E.1
Campbell, C.D.2
Kehoe, S.M.3
-
13
-
-
84863304598
-
-
R Foundation for Statistical Computing, Vienna, Austria,
-
R Development Core Team. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria, 2011.
-
(2011)
R: a language and environment for statistical computing
-
-
-
14
-
-
80053014471
-
Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations
-
Marchetti A, Felicioni L, Malatesta S, et al. Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations. J Clin Oncol 2011;29:3574-9.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3574-3579
-
-
Marchetti, A.1
Felicioni, L.2
Malatesta, S.3
-
15
-
-
68049088934
-
EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases
-
Schmid K, Oehl N, Wrba F, et al. EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clin Cancer Res 2009;15:4554-60.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4554-4560
-
-
Schmid, K.1
Oehl, N.2
Wrba, F.3
-
16
-
-
79956316170
-
Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations
-
Paik PK, Arcila ME, Fara M, et al. Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. J Clin Oncol 2011;29:2046-51.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2046-2051
-
-
Paik, P.K.1
Arcila, M.E.2
Fara, M.3
-
17
-
-
84875392086
-
Patterns of DNA mutations and ALK rearrangement in resected node negative lung adenocarcinoma
-
Yip PY, Yu B, Cooper WA, et al. Patterns of DNA mutations and ALK rearrangement in resected node negative lung adenocarcinoma. J Thorac Oncol 2013;8:408-14.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 408-414
-
-
Yip, P.Y.1
Yu, B.2
Cooper, W.A.3
-
18
-
-
80155191727
-
-
Cancer series no. 64. Australian Institute of Health and Welfare, Canberra,
-
Australian Institute of Health and Welfare. Lung cancer in Australia: an overview. Cancer series no. 64. Australian Institute of Health and Welfare, Canberra, 2011.
-
(2011)
Lung cancer in Australia: an overview
-
-
-
19
-
-
84861083983
-
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial
-
Falchook GS, Long GV, Kurzrock R, et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet 2012;379:1893-901.
-
(2012)
Lancet
, vol.379
, pp. 1893-1901
-
-
Falchook, G.S.1
Long, G.V.2
Kurzrock, R.3
-
20
-
-
74249123333
-
ALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancer
-
Solomon B, Varella-Garcia M, Camidge DR. ALK gene rearrangements: a new therapeutic target in a molecularly defined subset of non-small cell lung cancer. J Thorac Oncol 2009;4:1450-4.
-
(2009)
J Thorac Oncol
, vol.4
, pp. 1450-1454
-
-
Solomon, B.1
Varella-Garcia, M.2
Camidge, D.R.3
-
21
-
-
22044453790
-
Erlotinib in lung cancer-molecular and clinical predictors of outcome
-
Tsao MS, Sakurada A, Cutz JC, et al. Erlotinib in lung cancer-molecular and clinical predictors of outcome. N Engl J Med 2005;353:133-44.
-
(2005)
N Engl J Med
, vol.353
, pp. 133-144
-
-
Tsao, M.S.1
Sakurada, A.2
Cutz, J.C.3
-
22
-
-
75549087826
-
COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer
-
Forbes SA, Tang G, Bindal N, et al. COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer. Nucleic Acids Res 2010;38:D652-7.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. D652-D657
-
-
Forbes, S.A.1
Tang, G.2
Bindal, N.3
-
23
-
-
75749102647
-
Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial
-
Roth AD, Tejpar S, Delorenzi M, et al. Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol 2010;28:466-74.
-
(2010)
J Clin Oncol
, vol.28
, pp. 466-474
-
-
Roth, A.D.1
Tejpar, S.2
Delorenzi, M.3
-
24
-
-
85047689482
-
BRAF mutations in colorectal cancer are associated with distinct clinical characteristics and worse prognosis
-
Kalady MF, Dejulius KL, Sanchez JA, et al. BRAF mutations in colorectal cancer are associated with distinct clinical characteristics and worse prognosis. Dis Colon Rectum 2012;55:128-33.
-
(2012)
Dis Colon Rectum
, vol.55
, pp. 128-133
-
-
Kalady, M.F.1
Dejulius, K.L.2
Sanchez, J.A.3
-
25
-
-
69949088331
-
Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation
-
Raso MG, Behrens C, Herynk MH, et al. Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation. Clin Cancer Res 2009;15:5359-68.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5359-5368
-
-
Raso, M.G.1
Behrens, C.2
Herynk, M.H.3
-
26
-
-
65349111219
-
Micropapillary lung adenocarcinoma: EGFR, K-ras, and BRAF mutational profile
-
De Oliveira Duarte Achcar R, Nikiforova MN, Yousem SA. Micropapillary lung adenocarcinoma: EGFR, K-ras, and BRAF mutational profile. Am J Clin Pathol 2009;131:694-700.
-
(2009)
Am J Clin Pathol
, vol.131
, pp. 694-700
-
-
De Oliveira Duarte Achcar, R.1
Nikiforova, M.N.2
Yousem, S.A.3
-
27
-
-
0036894746
-
BRAF and RAS mutations in human lung cancer and melanoma
-
Brose MS, Volpe P, Feldman M, et al. BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res 2002;62:6997-7000.
-
(2002)
Cancer Res
, vol.62
, pp. 6997-7000
-
-
Brose, M.S.1
Volpe, P.2
Feldman, M.3
-
28
-
-
20944448124
-
Functional consequences of mutations in a putative Akt phosphorylation motif of B-raf in human cancers
-
Ikenoue T, Kanai F, Hikiba Y, et al. Functional consequences of mutations in a putative Akt phosphorylation motif of B-raf in human cancers. Mol Carcinog 2005;43:59-63.
-
(2005)
Mol Carcinog
, vol.43
, pp. 59-63
-
-
Ikenoue, T.1
Kanai, F.2
Hikiba, Y.3
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