miR-34a inhibits cell proliferation in prostate cancer by downregulation of SIRT1 expression

Oncology Letters

Volumn 10, Issue 5, 2015, Pages 3223-3227

  Duan, Kun ^a   Ge, Yong Chao ^a   Zhang, Xue Pei ^b   Wu, Shu Yi ^c   Feng, Jin Shun ^a   Chen, Shi Lin ^a   Zhang, Li ^a   Yuan, Zhi Hao ^a   Fu, Chao Hong ^a  

^a The Third People s Hospital of Zhengzhou   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^c HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Cell proliferation; Human prostate cancer cell; MicroRNA 34a; Sirtuin 1

Indexed keywords

MICRORNA 34A; SIRTUIN 1;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; DOWN REGULATION; DRUG TARGETING; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; PROSTATE CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84942422717     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2015.3645     Document Type: Article

References (32)

1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D and Bray F: Cancer incidence and mortality worldwide: Sources, methods, and major patterns in GLOBOCAN 2012. Int J Cancer 136: E359-E386, 2015.
2. Gade TP, Hassen W, Santos E, Gunset G, Saudemont A, Gong MC, Brentjens R, Zhong XS, Stephan M, Stefanski J, et al: Targeted elimination of prostate cancer by genetically directed human T lymphocytes. Cancer Res 65: 9080-9088, 2005.
3. Salter KH, Acharya CR, Walters KS, Redman R, Anguiano A, Garman KS, Anders CK, Mukherjee S, Dressman HK, Barry WT, et al: An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer. PLoS One 3: e1908, 2008.
4. Denli AM, Tops BB, Plasterk RH, Ketting RF and Hannon GJ: Processing of primary microRNAs by the Microprocessor complex. Nature 432: 231-235, 2004.
5. Huntzinger E and Izaurralde E: Gene silencing by microRNAs: Contributions of translational repression and mRNA decay. Nat Rev Genet 12: 99-110, 2011.
6. Kloosterman WP and Plasterk RH: The diverse functions of microRNAs in animal development and disease. Dev Cell 11: 441-450, 2006.
7. Li XJ, Ren ZJ and Tang JH: MicroRNA-34a: A potential therapeutic target in human cancer. Cell Death Dis 5: e1327, 2014.
8. Guessous F, Zhang Y, Kofman A, Catania A, Li Y, Schiff D, Purow B and Abounader R: MicroRNA-34a is tumor suppressive in brain tumors and glioma stem cells. Cell Cycle 9: 1031-1036, 2010.
9. Ji Q, Hao X, Meng Y, Zhang M, Desano J, Fan D and Xu L: Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer 8: 266, 2008.
10. Maroof H, Salajegheh A, Smith RA and Lam AK: Role of microRNA-34 family in cancer with particular reference to cancer angiogenesis. Exp Mol Pathol 97: 298-304, 2014.
11. Satoh A, Stein L and Imai S: The role of mammalian sirtuins in the regulation of metabolism, aging and longevity. Handb Exp Pharmacol 206: 125-162, 2011.
12. Kabra N, Li Z, Chen L, Li B, Zhang X, Wang C, Yeatman T, Coppola D and Chen J: SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem 284: 18210-18217, 2009.
13. Jung W, Hong KD, Jung WY, Lee E, Shin BK, Kim HK, Kim A and Kim BH: SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer. Korean J Pathol 47: 332-339, 2013.
14. Kim JR, Moon YJ, Kwon KS, Bae JS, Wagle S, Yu TK, Kim KM, Park HS, Lee JH, Moon WS, et al: Expression of SIRT1 and DBC1 is associated with poor prognosis of soft tissue sarcomas. PLoS One 8: e74738, 2013.
15. Leko V, Park G, Lao U, et al: Enterocyte-specific inactivation of SIRT1 reduces tumor load in the APC (+/min) mouse model. PLoS One 8: e66283, 2013.
16. Knight JR, Allison SJ and Milner J: Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity. Open Biol 3: 130-135, 2013.
17. Revollo JR and Li X: The ways and means that fine tune SIRT1 activity. Trends Biochem Sci 38: 160-167, 2013.
18. Zhang XL, Chen ML and Zhou SL: Fentanyl increases colorectal carcinoma cell apoptosis by inhibition of NF-κB in a Sirt1-dependent manner. Asian Pac J Cancer Prev 15: 10015-10020, 2014.
19. The American Joint Committee on Cancer: The 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol 17: 1471-1474, 2010.
20. Welch C, Chen Y and Stallings RL: MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 26: 5017-5022, 2007.
21. Moretti RM, Montagnani Mareli M, Taylor DM, Martini PG, Marzagalli M and Limonta P: Gonadotropin-releasing hormone agonists sensitize and resensitize, prostate cancer cells to docetaxel in a p53-dependent manner. PLoS One 9: e93713, 2014.
22. Lodygin D, Tarasov V, Epanchintsev A, Berking C, Knyazeva T, Körner H, Knyazev P, Diebold J and Hermeking H: Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 7: 2591-2600, 2008.
23. Yamakuchi M, Ferlito M and Lowenstein CJ: MiR-34a repression of SIRT1 regulates apoptosis. Proc Natl Acad Sci U S A 105: 13421-13426, 2008.
24. Hwang BJ, Madabushi A, Jin J, Lin SY and Lu AL: Histone/protein deacetylase SIRT1 is an anticancer therapeutic target. Am J Cancer Res 4: 211-221, 2014.
25. Zhao T, Li J and Chen AF: MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1. Am J Physiol Endocrinol Metab 299: E110-E116, 2010.
26. Akao Y, Noguchi S, Iio A, Kojima K, Takagi T and Naoe T: Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells. Cancer Lett 300: 197-204, 2011.
27. Li L, Yuan L, Luo J, Gao J, Guo J and Xie X: MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1. Clin Exp Med 13: 109-117, 2013.
28. Chapman EJ, Kelly G and Knowles MA: Genes involved in differentiation, stem cell renewal and tumorigenesis are modulated in telomerase-immortalized human urothelial cells. Mol Cancer Res 6: 1154-1168, 2008.
29. Audrito V, Rossi D, Gottardi D, et al: Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network. Cancer Res 71: 4473-4483, 2011.
30. Bommer GT, Feng Y, Kaczorowski AJ, Gerin I, Kuick R, Love RE, Zhai Y, Giordano TJ, et al: p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 17: 1298-1307, 2007.
31. Chen F and Hu SJ: Effect of microRNA-34a in cell cycle, differentiation and apoptosis: A review. J Biochem Mol Toxicol 26: 79-86, 2012.
32. Ito T, Yagi S and Yamakuchi M: MicroRNA-34a regulation of endothelial senescence. Biochem Biophys Res Commun 398: 735-740, 2010.