메뉴 건너뛰기




Volumn 14, Issue 1, 2015, Pages

BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells

Author keywords

BMP4; Lung cancer; Metastasis; miR 200

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; MEMBRANE PROTEIN; MICRORNA 200; MYOSIN; PROTEIN JAG2; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; JAG2 PROTEIN, MOUSE; MICRORNA; PROTEIN JAGGED 2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR GATA 5;

EID: 84942367330     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0441-y     Document Type: Article
Times cited : (58)

References (36)
  • 2
    • 84904607389 scopus 로고    scopus 로고
    • Biomarkers that currently affect clinical practice in lung cancer: EGFR, ALK, MET, ROS-1, and KRAS
    • Korpanty GJ, Graham DM, Vincent MD, Leighl NB. Biomarkers that currently affect clinical practice in lung cancer: EGFR, ALK, MET, ROS-1, and KRAS. Front Oncol. 2014;4:204.
    • (2014) Front Oncol , vol.4 , pp. 204
    • Korpanty, G.J.1    Graham, D.M.2    Vincent, M.D.3    Leighl, N.B.4
  • 3
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009;119:1420-8.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 5
    • 35349020997 scopus 로고    scopus 로고
    • A genetic mouse model for metastatic lung cancer with gender differences in survival
    • Zheng S, El-Naggar AK, Kim ES, Kurie JM, Lozano G. A genetic mouse model for metastatic lung cancer with gender differences in survival. Oncogene. 2007;26:6896-904.
    • (2007) Oncogene , vol.26 , pp. 6896-6904
    • Zheng, S.1    El-Naggar, A.K.2    Kim, E.S.3    Kurie, J.M.4    Lozano, G.5
  • 6
    • 70349142665 scopus 로고    scopus 로고
    • Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
    • Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, Goodall GJ, et al. Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev. 2009;23:2140-51.
    • (2009) Genes Dev , vol.23 , pp. 2140-2151
    • Gibbons, D.L.1    Lin, W.2    Creighton, C.J.3    Rizvi, Z.H.4    Gregory, P.A.5    Goodall, G.J.6
  • 7
    • 77956230322 scopus 로고    scopus 로고
    • The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?
    • Brabletz S, Brabletz T. The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer? EMBO Rep. 2010;11:670-7.
    • (2010) EMBO Rep , vol.11 , pp. 670-677
    • Brabletz, S.1    Brabletz, T.2
  • 8
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 2008;68:7846-54.
    • (2008) Cancer Res , vol.68 , pp. 7846-7854
    • Bracken, C.P.1    Gregory, P.A.2    Kolesnikoff, N.3    Bert, A.G.4    Wang, J.5    Shannon, M.F.6
  • 9
    • 84865858355 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior
    • Kallioniemi A. Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior. Cancer Genet. 2012;205:267-77.
    • (2012) Cancer Genet , vol.205 , pp. 267-277
    • Kallioniemi, A.1
  • 10
    • 33845610993 scopus 로고    scopus 로고
    • Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
    • Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, Broggi G, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature. 2006;444:761-5.
    • (2006) Nature , vol.444 , pp. 761-765
    • Piccirillo, S.G.1    Reynolds, B.A.2    Zanetti, N.3    Lamorte, G.4    Binda, E.5    Broggi, G.6
  • 11
    • 35848963864 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 induces epithelial-mesenchymal transition through MSX2 induction on pancreatic cancer cell line
    • Hamada S, Satoh K, Hirota M, Kimura K, Kanno A, Masamune A, et al. Bone morphogenetic protein 4 induces epithelial-mesenchymal transition through MSX2 induction on pancreatic cancer cell line. J Cell Physiol. 2007;213:768-74.
    • (2007) J Cell Physiol , vol.213 , pp. 768-774
    • Hamada, S.1    Satoh, K.2    Hirota, M.3    Kimura, K.4    Kanno, A.5    Masamune, A.6
  • 12
    • 79953329774 scopus 로고    scopus 로고
    • The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
    • Yang Y, Ahn YH, Gibbons DL, Zang Y, Lin W, Thilaganathan N, et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest. 2011;121:1373-85.
    • (2011) J Clin Invest , vol.121 , pp. 1373-1385
    • Yang, Y.1    Ahn, Y.H.2    Gibbons, D.L.3    Zang, Y.4    Lin, W.5    Thilaganathan, N.6
  • 13
    • 84902152865 scopus 로고    scopus 로고
    • ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism
    • Yang Y, Ahn YH, Chen Y, Tan X, Guo L, Gibbons DL, et al. ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism. J Clin Invest. 2014;124:2696-708.
    • (2014) J Clin Invest , vol.124 , pp. 2696-2708
    • Yang, Y.1    Ahn, Y.H.2    Chen, Y.3    Tan, X.4    Guo, L.5    Gibbons, D.L.6
  • 14
    • 0037330475 scopus 로고    scopus 로고
    • Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6
    • Nemer G, Nemer M. Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6. Dev Biol. 2003;254:131-48.
    • (2003) Dev Biol , vol.254 , pp. 131-148
    • Nemer, G.1    Nemer, M.2
  • 15
    • 0032711514 scopus 로고    scopus 로고
    • Smad1 and Smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo
    • Dick A, Meier A, Hammerschmidt M. Smad1 and Smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo. Dev Dyn. 1999;216:285-98.
    • (1999) Dev Dyn , vol.216 , pp. 285-298
    • Dick, A.1    Meier, A.2    Hammerschmidt, M.3
  • 16
  • 17
    • 58149191544 scopus 로고    scopus 로고
    • Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
    • Jaffe AB, Kaji N, Durgan J, Hall A. Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J Cell Biol. 2008;183:625-33.
    • (2008) J Cell Biol , vol.183 , pp. 625-633
    • Jaffe, A.B.1    Kaji, N.2    Durgan, J.3    Hall, A.4
  • 18
    • 77951174042 scopus 로고    scopus 로고
    • LGN regulates mitotic spindle orientation during epithelial morphogenesis
    • Zheng Z, Zhu H, Wan Q, Liu J, Xiao Z, Siderovski DP, et al. LGN regulates mitotic spindle orientation during epithelial morphogenesis. J Cell Biol. 2010;189:275-88.
    • (2010) J Cell Biol , vol.189 , pp. 275-288
    • Zheng, Z.1    Zhu, H.2    Wan, Q.3    Liu, J.4    Xiao, Z.5    Siderovski, D.P.6
  • 19
    • 84859196315 scopus 로고    scopus 로고
    • RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization
    • Lordier L, Bluteau D, Jalil A, Legrand C, Pan J, Rameau P, et al. RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization. Nat Commun. 2012;3:717.
    • (2012) Nat Commun , vol.3 , pp. 717
    • Lordier, L.1    Bluteau, D.2    Jalil, A.3    Legrand, C.4    Pan, J.5    Rameau, P.6
  • 20
    • 0347519180 scopus 로고    scopus 로고
    • Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation
    • Dahlqvist C, Blokzijl A, Chapman G, Falk A, Dannaeus K, Ibanez CF, et al. Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation. Development. 2003;130:6089-99.
    • (2003) Development , vol.130 , pp. 6089-6099
    • Dahlqvist, C.1    Blokzijl, A.2    Chapman, G.3    Falk, A.4    Dannaeus, K.5    Ibanez, C.F.6
  • 21
    • 0029162584 scopus 로고
    • Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
    • Liem Jr KF, Tremml G, Roelink H, Jessell TM. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell. 1995;82:969-79.
    • (1995) Cell , vol.82 , pp. 969-979
    • Liem, K.F.1    Tremml, G.2    Roelink, H.3    Jessell, T.M.4
  • 22
    • 0029936125 scopus 로고    scopus 로고
    • A role for BMP-4 in the development of subcutaneous cartilage
    • Watanabe Y, Le Douarin NM. A role for BMP-4 in the development of subcutaneous cartilage. Mech Dev. 1996;57:69-78.
    • (1996) Mech Dev , vol.57 , pp. 69-78
    • Watanabe, Y.1    Douarin, N.M.2
  • 23
    • 84865133667 scopus 로고    scopus 로고
    • BMP4 administration induces differentiation of CD133+ hepatic cancer stem cells, blocking their contributions to hepatocellular carcinoma
    • Zhang L, Sun H, Zhao F, Lu P, Ge C, Li H, et al. BMP4 administration induces differentiation of CD133+ hepatic cancer stem cells, blocking their contributions to hepatocellular carcinoma. Cancer Res. 2012;72:4276-85.
    • (2012) Cancer Res , vol.72 , pp. 4276-4285
    • Zhang, L.1    Sun, H.2    Zhao, F.3    Lu, P.4    Ge, C.5    Li, H.6
  • 24
    • 81255124262 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 and -4 play tumor suppressive roles in human diffuse-type gastric carcinoma
    • Shirai YT, Ehata S, Yashiro M, Yanagihara K, Hirakawa K, Miyazono K. Bone morphogenetic protein-2 and -4 play tumor suppressive roles in human diffuse-type gastric carcinoma. Am J Pathol. 2011;179:2920-30.
    • (2011) Am J Pathol , vol.179 , pp. 2920-2930
    • Shirai, Y.T.1    Ehata, S.2    Yashiro, M.3    Yanagihara, K.4    Hirakawa, K.5    Miyazono, K.6
  • 27
    • 84858785411 scopus 로고    scopus 로고
    • Regulation of GATA4 transcriptional activity in cardiovascular development and disease
    • Zhou P, He A, Pu WT. Regulation of GATA4 transcriptional activity in cardiovascular development and disease. Curr Top Dev Biol. 2012;100:143-69.
    • (2012) Curr Top Dev Biol , vol.100 , pp. 143-169
    • Zhou, P.1    He, A.2    Pu, W.T.3
  • 28
    • 84879660620 scopus 로고    scopus 로고
    • DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation
    • Oda M, Kumaki Y, Shigeta M, Jakt LM, Matsuoka C, Yamagiwa A, et al. DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation. PLoS Genet. 2013;9:e1003574.
    • (2013) PLoS Genet , vol.9 , pp. e1003574
    • Oda, M.1    Kumaki, Y.2    Shigeta, M.3    Jakt, L.M.4    Matsuoka, C.5    Yamagiwa, A.6
  • 29
    • 84923251407 scopus 로고    scopus 로고
    • Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
    • Chen L, Gibbons DL, Goswami S, Cortez MA, Ahn YH, Byers LA, et al. Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression. Nat Commun. 2014;5:5241.
    • (2014) Nat Commun , vol.5 , pp. 5241
    • Chen, L.1    Gibbons, D.L.2    Goswami, S.3    Cortez, M.A.4    Ahn, Y.H.5    Byers, L.A.6
  • 30
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008;9:582-9.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6
  • 31
    • 84255191994 scopus 로고    scopus 로고
    • Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer
    • Schliekelman MJ, Gibbons DL, Faca VM, Creighton CJ, Rizvi ZH, Zhang Q, et al. Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. Cancer Res. 2011;71:7670-82.
    • (2011) Cancer Res , vol.71 , pp. 7670-7682
    • Schliekelman, M.J.1    Gibbons, D.L.2    Faca, V.M.3    Creighton, C.J.4    Rizvi, Z.H.5    Zhang, Q.6
  • 32
    • 79953293527 scopus 로고    scopus 로고
    • Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis
    • Durgan J, Kaji N, Jin D, Hall A. Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis. J Biol Chem. 2011;286:12461-74.
    • (2011) J Biol Chem , vol.286 , pp. 12461-12474
    • Durgan, J.1    Kaji, N.2    Jin, D.3    Hall, A.4
  • 33
    • 0032006529 scopus 로고    scopus 로고
    • Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis
    • Giansanti MG, Bonaccorsi S, Williams B, Williams EV, Santolamazza C, Goldberg ML, et al. Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis. Genes Dev. 1998;12:396-410.
    • (1998) Genes Dev , vol.12 , pp. 396-410
    • Giansanti, M.G.1    Bonaccorsi, S.2    Williams, B.3    Williams, E.V.4    Santolamazza, C.5    Goldberg, M.L.6
  • 34
    • 84900969668 scopus 로고    scopus 로고
    • miR-200a-mediated suppression of non-muscle heavy chain IIb inhibits meningioma cell migration and tumor growth in vivo
    • Senol O, Schaaij-Visser TB, Erkan EP, Dorfer C, Lewandrowski G, Pham TV, et al. miR-200a-mediated suppression of non-muscle heavy chain IIb inhibits meningioma cell migration and tumor growth in vivo. Oncogene. 2015;34:1790-8.
    • (2015) Oncogene , vol.34 , pp. 1790-1798
    • Senol, O.1    Schaaij-Visser, T.B.2    Erkan, E.P.3    Dorfer, C.4    Lewandrowski, G.5    Pham, T.V.6
  • 35
    • 84886150771 scopus 로고    scopus 로고
    • Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin
    • Langenfeld E, Deen M, Zachariah E, Langenfeld J. Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin. Mol Cancer. 2013;12:129.
    • (2013) Mol Cancer , vol.12 , pp. 129
    • Langenfeld, E.1    Deen, M.2    Zachariah, E.3    Langenfeld, J.4
  • 36
    • 51649091930 scopus 로고    scopus 로고
    • Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis
    • Creighton CJ, Casa A, Lazard Z, Huang S, Tsimelzon A, Hilsenbeck SG, et al. Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis. J Clin Oncol. 2008;26:4078-85.
    • (2008) J Clin Oncol , vol.26 , pp. 4078-4085
    • Creighton, C.J.1    Casa, A.2    Lazard, Z.3    Huang, S.4    Tsimelzon, A.5    Hilsenbeck, S.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.