Phthalocyanine photosensitizers as contrast agents for in vivo photoacoustic tumor imaging

Biomedical Optics Express

Volumn 6, Issue 2, 2015, Pages 591-598

  Attia, Amalina Bte Ebrahim ^a   Balasundaram, Ghayathri ^a   Driessen, Wouter ^b,c   Ntziachristos, Vasilis ^b   Olivo, Malini ^a,d  

^a AGENCY FOR SCIENCE   (Singapore)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c ITHERA MEDICAL GMBH   (Germany)

^d NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM COMPOUNDS; CHLORINE COMPOUNDS; DIAGNOSIS; MAMMALS; NONINVASIVE MEDICAL PROCEDURES; PHOTODYNAMIC THERAPY; TUMORS; ZINC COMPOUNDS;

BIODISTRIBUTIONS; BIOLOGICAL TISSUES; CONTRAST AGENT; MULTI-SPECTRAL; NON-INVASIVE DIAGNOSTICS; OPTOACOUSTIC TOMOGRAPHY; PHOTOACOUSTIC SIGNALS; ZN PHTHALOCYANINES;

PHOTOSENSITIZERS;

CONTRAST MEDIUM; PHTHALOCYANINE; PHTHALOCYANINE TETRASULFONIC ACID; TETRASULFOPHTHALOCYANINE ALUMINUM; TETRASULFOPHTHALOCYANINE ZINC; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATOPHORE; CONTROLLED STUDY; FEMALE; FLUORESCENCE IMAGING; HEMOGLOBIN BLOOD LEVEL; IMAGE RECONSTRUCTION; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; NON INVASIVE PROCEDURE; NONHUMAN; PHOTOACOUSTIC TOMOGRAPHY; PHOTOACOUSTIC TUMOR IMAGING; PHOTODYNAMIC THERAPY; SIGNAL PROCESSING;

MUS;

EID: 84942365117     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.6.000591     Document Type: Article

References (33)

1. A. Hellebust and R. Richards-Kortum, “Advances in molecular imaging: targeted optical contrast agents for cancer diagnostics,” Nanomedicine (Lond) 7(3), 429–445 (2012).
2. V. Ntziachristos, C. Bremer, and R. Weissleder, “Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging,” Eur. Radiol. 13(1), 195–208 (2003).
3. J. G. Fujimoto, C. Pitris, S. A. Boppart, and M. E. Brezinski, “Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy,” Neoplasia 2(1-2), 9–25 (2000).
4. L. V. Wang, “Multiscale photoacoustic microscopy and computed tomography,” Nat. Photonics 3(9), 503–509 (2009).
5. L. V. Wang and S. Hu, “Photoacoustic tomography: in vivo imaging from organelles to organs,” Science 335(6075), 1458–1462 (2012).
6. R. O. Esenaliev, A. A. Karabutov, and A. A. Oraevsky, “Sensitivity of laser opto-acoustic imaging in detection of small deeply embedded tumors,” IEEE J. Sel. Top. Quantum Electron. 5(4), 981–988 (1999).
7. G. Ku and L. V. Wang, “Deeply penetrating photoacoustic tomography in biological tissues enhanced with an optical contrast agent,” Opt. Lett. 30(5), 507–509 (2005).
8. T. L. Troy, D. L. Page, and E. M. Sevick-Muraca, “Optical properties of normal and diseased breast tissues: prognosis for optical mammography,” J. Biomed. Opt. 1(3), 342–355 (1996).
9. G. P. Luke, D. Yeager, and S. Y. Emelianov, “Biomedical applications of photoacoustic imaging with exogenous contrast agents,” Ann. Biomed. Eng. 40(2), 422–437 (2012).
10. L. Nie and X. Chen, “Structural and functional photoacoustic molecular tomography aided by emerging contrast agents,” Chem. Soc. Rev. 43(20), 7132–7170 (2014).
11. W. S. Poon, K. T. Schomacker, T. F. Deutsch, and R. L. Martuza, “Laser-induced fluorescence: experimental intraoperative delineation of tumor resection margins,” J. Neurosurg. 76(4), 679–686 (1992).
12. M. J. Witjes, O. C. Speelman, P. G. Nikkels, C. A. Nooren, J. M. Nauta, B. van der Holt, H. L. van Leengoed, W. M. Star, and J. L. Roodenburg, “In vivo fluorescence kinetics and localisation of aluminum phthalocyanine disulphonate in an autologous tumour model,” Br. J. Cancer 73(5), 573–580 (1996).
13. G. A. Wagnières, W. M. Star, and B. C. Wilson, “In vivo fluorescence spectroscopy and imaging for oncological applications,” Photochem. Photobiol. 68(5), 603–632 (1998).
14. C. J. H. Ho, G. Balasundaram, W. Driessen, R. McLaren, C. L. Wong, U. S. Dinish, A. B. E. Attia, V. Ntziachristos, and M. Olivo, “Multifunctional Photosensitizer-Based Contrast Agents for Photoacoustic Imaging,” Sci. Rep. 4, 5342 (2014).
15. N. Sekkat, H. van den Bergh, T. Nyokong, and N. Lange, “Like a bolt from the blue: phthalocyanines in biomedical optics,” Molecules 17(1), 98–144 (2012).
16. A. Beeby, S. FitzGerald, and C. F. Stanley, “A photophysical study of protonated (tetra-tertbutylphthalocyaninato) zinc,” J. Chem. Soc., Perkin Trans. 2 2001(10), 1978–1982 (2001).
17. H. L. van Leengoed, V. Cuomo, A. A. Versteeg, N. van der Veen, G. Jori, and W. M. Star, “In vivo fluorescence and photodynamic activity of zinc phthalocyanine administered in liposomes,” Br. J. Cancer 69(5), 840–845 (1994).
18. A. Beeby, S. FitzGerald, and C. F. Stanley, “Protonation of Tetrasulfonated Zinc Phthalocyanine in Aqueous Acetonitrile Solution,” Photochem. Photobiol. 74(4), 566–569 (2001).
19. N. B. R. Vittar, C. G. Prucca, C. Strassert, J. Awruch, and V. A. Rivarola, “Cellular inactivation and antitumor efficacy of a new zinc phthalocyanine with potential use in photodynamic therapy,” Int. J. Biochem. Cell Biol. 40(10), 2192–2205 (2008).
20. B. Zhao, J.-J. Yin, P. J. Bilski, C. F. Chignell, J. E. Roberts, and Y.-Y. He, “Enhanced photodynamic efficacy towards melanoma cells by encapsulation of Pc4 in silica nanoparticles,” Toxicol. Appl. Pharmacol. 241(2), 163–172 (2009).
21. R. Ma, A. Taruttis, V. Ntziachristos, and D. Razansky, “Multispectral optoacoustic tomography (MSOT) scanner for whole-body small animal imaging,” Opt. Express 17(24), 21414–21426 (2009).
22. V. Ntziachristos and D. Razansky, “Molecular imaging by means of multispectral optoacoustic tomography (MSOT),” Chem. Rev. 110(5), 2783–2794 (2010).
23. A. Rosenthal, D. Razansky, and V. Ntziachristos, “Fast semi-analytical model-based acoustic inversion for quantitative optoacoustic tomography,” IEEE Trans. Med. Imaging 29(6), 1275–1285 (2010).
24. S. Tzoumas, N. Deliolanis, S. Morscher, and V. Ntziachristos, “Un-mixing Molecular Agents from Absorbing Tissue in Multispectral Optoacoustic Tomography,” IEEE Trans. Med. Imaging 33(1), 48–60 (2014).
25. D. Razansky, C. Vinegoni, and V. Ntziachristos, “Multispectral photoacoustic imaging of fluorochromes in small animals,” Opt. Lett. 32(19), 2891–2893 (2007).
26. Z. Li, H. Li, Z. Zeng, W. Xie, and W. R. Chen, “Determination of optical absorption coefficient with focusing photoacoustic imaging,” J. Biomed. Opt. 17(6), 061216 (2012).
27. J. Liu, J. Geng, L.-D. Liao, N. Thakor, X. Gao, and B. Liu, “Conjugated polymer nanoparticles for photoacoustic vascular imaging,” Polym. Chem. 5(8), 2854–2862 (2014).
28. A. Abuteen, S. Zanganeh, J. Akhigbe, L. P. Samankumara, A. Aguirre, N. Biswal, M. Braune, A. Vollertsen, B. Röder, C. Brückner, and Q. Zhu, “The evaluation of NIR-absorbing porphyrin derivatives as contrast agents in photoacoustic imaging,” Phys. Chem. Chem. Phys. 15(42), 18502–18509 (2013).
29. A. Ogunsipe and T. Nyokong, “Photophysical and photochemical studies of sulphonated non-transition metal phthalocyanines in aqueous and non-aqueous media,” J. Photochem. Photobiol. Chem. 173(2), 211–220 (2005).
30. A. Borgatti-Jeffreys, S. B. Hooser, M. A. Miller, and M. D. Lucroy, “Phase I clinical trial of the use of zinc phthalocyanine tetrasulfonate as a photosensitizer for photodynamic therapy in dogs,” Am. J. Vet. Res. 68(4), 399–404 (2007).
31. University of Arkansas for Medical Sciences, Department of Neurobiology and Developmental Sciences, “Arteries of the Abdomen- Arranged Alphabetically,” http://anatomy.uams.edu/arteries_abdomen.html.
32. University of Arkansas for Medical Sciences, Department of Neurobiology and Developmental Sciences, “Selected Veins of the Abdomen - Listed Alphabetically,” http://anatomy.uams.edu/veins_abdomen.html.
33. H. L. van Leengoed, N. van der Veen, A. A. Versteeg, R. Ouellet, J. E. van Lier, and W. M. Star, “In vivo fluorescence kinetics of phthalocyanines in a skin-fold observation chamber model: role of central metal ion and degree of sulfonation,” Photochem. Photobiol. 58(2), 233–237 (1993).