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Volumn 211, Issue 5, 2015, Pages 729-735

Response-guided boceprevir-based triple therapy in HIV/HCV-coinfected patients: The HIVCOBOC-RGT study

Author keywords

Antiviral agents; Boceprevir; Hepatitis C; HIV; Response guided therapy

Indexed keywords

ALPHA2A INTERFERON; ANTIBIOTIC AGENT; BOCEPREVIR; INTERLEUKIN 28B; RIBAVIRIN; ALPHA INTERFERON; ANTIVIRUS AGENT; MACROGOL DERIVATIVE; N-(3-AMINO-1-(CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL)-3-(2-((((1,1-DIMETHYLETHYL)AMINO)CARBONYL)AMINO)-3,3-DIMETHYL-1-OXOBUTYL)-6,6-DIMETHYL-3-AZABICYCLO(3.1.0)HEXAN-2-CARBOXAMIDE; PEGINTERFERON ALPHA2A; PROLINE; RECOMBINANT PROTEIN; VIRUS RNA;

EID: 84942328942     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu516     Document Type: Article
Times cited : (13)

References (34)
  • 1
    • 77953913058 scopus 로고    scopus 로고
    • Factors associated with specific causes of death amongst HIV-positive individuals in the D: A: D Study
    • Smith C, Sabin CA, Lundgren JD, et al. Factors associated with specific causes of death amongst HIV-positive individuals in the D:A:D Study. AIDS 2010;24:1537-48.
    • (2010) AIDS , vol.24 , pp. 1537-1548
    • Smith, C.1    Sabin, C.A.2    Lundgren, J.D.3
  • 2
    • 30144437514 scopus 로고    scopus 로고
    • Epidemiology of viral hepatitis and HIV co-infection
    • Alter MJ. Epidemiology of viral hepatitis and HIV co-infection. J Hep-atol 2006;44:S6-9.
    • (2006) J Hep-atol , vol.44 , pp. S6-S9
    • Alter, M.J.1
  • 3
    • 84896703070 scopus 로고    scopus 로고
    • Fibrosis progression in human immunodeficiency virus/hepatitis C virus coinfected adults: Prospective analysis of 435 liver biopsy pairs
    • Konerman MA, Mehta SH, Sutcliffe CG, et al. Fibrosis progression in human immunodeficiency virus/hepatitis C virus coinfected adults: prospective analysis of 435 liver biopsy pairs. Hepatology 2014;59:767-75.
    • (2014) Hepatology , vol.59 , pp. 767-775
    • Konerman, M.A.1    Mehta, S.H.2    Sutcliffe, C.G.3
  • 4
    • 84922712746 scopus 로고    scopus 로고
    • Revisiting liver disease progression in HIV/HCV-coinfected patients: The influence of Vitamin D, insulin resistance, immune status, IL28B and PNPLA3
    • Mandorfer M, Payer BA, Schwabl P, et al. Revisiting liver disease progression in HIV/HCV-coinfected patients: the influence of vitamin D, insulin resistance, immune status, IL28B and PNPLA3. Liver Int 2014; doi:10.1111/liv. 12615.
    • (2014) Liver Int
    • Mandorfer, M.1    Payer, B.A.2    Schwabl, P.3
  • 5
    • 0035882187 scopus 로고    scopus 로고
    • Influence of human immunodeficiency virus infection on the course of hepatitis C virus infection: A meta-analysis
    • Graham CS, Baden LR, Yu E, et al. Influence of human immunodeficiency virus infection on the course of hepatitis C virus infection: a meta-analysis. Clin Infect Dis 2001;33:562-9.
    • (2001) Clin Infect Dis , vol.33 , pp. 562-569
    • Graham, C.S.1    Baden, L.R.2    Yu, E.3
  • 6
    • 68949183159 scopus 로고    scopus 로고
    • Sustained virological response to interferon plus ribavirin reduces liver-related complications and mortality in patients coinfected with human immunodeficiency virus and hepatitis C virus
    • Berenguer J, Alvarez-Pellicer J, Martin PM, et al. Sustained virological response to interferon plus ribavirin reduces liver-related complications and mortality in patients coinfected with human immunodeficiency virus and hepatitis C virus. Hepatology 2009;50:407-13.
    • (2009) Hepatology , vol.50 , pp. 407-413
    • Berenguer, J.1    Alvarez-Pellicer, J.2    Martin, P.M.3
  • 7
    • 84864915019 scopus 로고    scopus 로고
    • Sustained virological response to interferon plus ribavirin reduces non-liver-related mortality in patients coinfected with HIV and Hepatitis C virus
    • Berenguer J, Rodriguez E, Miralles P, et al. Sustained virological response to interferon plus ribavirin reduces non-liver-related mortality in patients coinfected with HIV and Hepatitis C virus. Clin Infect Dis 2012;55:728-36.
    • (2012) Clin Infect Dis , vol.55 , pp. 728-736
    • Berenguer, J.1    Rodriguez, E.2    Miralles, P.3
  • 8
    • 84888296566 scopus 로고    scopus 로고
    • The impact of interleukin 28B rs12979860 single nucleotide polymorphism and liver fibrosis stage on response-guided therapy in HIV/HCV-coinfected patients
    • Mandorfer M, Neukam K, Reiberger T, et al. The impact of interleukin 28B rs12979860 single nucleotide polymorphism and liver fibrosis stage on response-guided therapy in HIV/HCV-coinfected patients. AIDS 2013;27:2707-14.
    • (2013) AIDS , vol.27 , pp. 2707-2714
    • Mandorfer, M.1    Neukam, K.2    Reiberger, T.3
  • 9
    • 84864323143 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for HIV-HCV genotype 1 coinfected patients: A randomized international trial
    • Rodriguez-Torres M, Slim J, Bhatti L, et al. Peginterferon alfa-2a plus ribavirin for HIV-HCV genotype 1 coinfected patients: a randomized international trial. HIV Clin Trials 2012;13:142-52.
    • (2012) HIV Clin Trials , vol.13 , pp. 142-152
    • Rodriguez-Torres, M.1    Slim, J.2    Bhatti, L.3
  • 10
    • 84899829423 scopus 로고    scopus 로고
    • Therapeutic potential of and treatment with boceprevir/telaprevir-based triple-therapy in HIV/chronic hepatitis C co-infected patients in a real-world setting
    • Mandorfer M, Payer BA, Niederecker A, et al. Therapeutic potential of and treatment with boceprevir/telaprevir-based triple-therapy in HIV/chronic hepatitis C co-infected patients in a real-world setting. AIDS Patient Care STDS 2014;28:221-7.
    • (2014) AIDS Patient Care STDS , vol.28 , pp. 221-227
    • Mandorfer, M.1    Payer, B.A.2    Niederecker, A.3
  • 11
    • 84879799809 scopus 로고    scopus 로고
    • Combination therapy with telaprevir for chronic hepatitis C virus genotype 1 infection in patients with HIV: A randomized trial
    • Sulkowski MS, Sherman KE, Dieterich DT, et al. Combination therapy with telaprevir for chronic hepatitis C virus genotype 1 infection in patients with HIV: a randomized trial. Ann Intern Med 2013;159:86-96.
    • (2013) Ann Intern Med , vol.159 , pp. 86-96
    • Sulkowski, M.S.1    Sherman, K.E.2    Dieterich, D.T.3
  • 12
    • 84879795434 scopus 로고    scopus 로고
    • Boceprevir versus placebo with pegylated interferon alfa-2b and ribavirin for treatment of hepatitis C virus genotype 1 in patients with HIV: A randomised, double-blind, controlled phase 2 trial
    • Sulkowski M, Pol S, Mallolas J, et al. Boceprevir versus placebo with pegylated interferon alfa-2b and ribavirin for treatment of hepatitis C virus genotype 1 in patients with HIV: a randomised, double-blind, controlled phase 2 trial. Lancet Infect Dis 2013;13:597-605.
    • (2013) Lancet Infect Dis , vol.13 , pp. 597-605
    • Sulkowski, M.1    Pol, S.2    Mallolas, J.3
  • 13
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011;364:1195-206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone, J.2    Bacon, B.R.3
  • 14
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011;364:1207-17.
    • (2011) N Engl J Med , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 15
    • 84881316397 scopus 로고    scopus 로고
    • High SVR rates (SVR4) for 12-week total telaprevir combination therapy in IL28B CC treatment-naïves and prior relapsers with G1 chronic hepatitis C: CONCISE interim analysis
    • Nelson DR, Poordad F, Feld JJ, et al. High SVR rates (SVR4) for 12-week total telaprevir combination therapy in IL28B CC treatment-naïves and prior relapsers with G1 chronic hepatitis C: CONCISE interim analysis. J Hepatol 2013;58:S362.
    • (2013) J Hepatol , vol.58 , pp. S362
    • Nelson, D.R.1    Poordad, F.2    Feld, J.J.3
  • 17
    • 84870018201 scopus 로고    scopus 로고
    • Recommendations for standardized nomenclature and definitions of viral response in trials of hepatitis C virus investigational agents
    • Wedemeyer H, Jensen DM, Godofsky E, et al. Recommendations for standardized nomenclature and definitions of viral response in trials of hepatitis C virus investigational agents. Hepatology 2012;56:2398-403.
    • (2012) Hepatology , vol.56 , pp. 2398-2403
    • Wedemeyer, H.1    Jensen, D.M.2    Godofsky, E.3
  • 18
    • 84860919169 scopus 로고    scopus 로고
    • IL28B and interferon-gamma in-ducible protein 10 for prediction of rapid virologic response and sustained virologic response in HIV-HCV-coinfected patients
    • Payer BA, Reiberger T, Aberle J, et al. IL28B and interferon-gamma in-ducible protein 10 for prediction of rapid virologic response and sustained virologic response in HIV-HCV-coinfected patients. Eur J Clin Invest 2012;42:599-606.
    • (2012) Eur J Clin Invest , vol.42 , pp. 599-606
    • Payer, B.A.1    Reiberger, T.2    Aberle, J.3
  • 19
    • 84864031085 scopus 로고    scopus 로고
    • Noninvasive screening for liver fibrosis and portal hypertension by transient elastography- A large single center experience
    • Reiberger T, Ferlitsch A, Payer BA, et al. Noninvasive screening for liver fibrosis and portal hypertension by transient elastography- A large single center experience. Wiener Klinische Wochenschrift 2012;124:395-402.
    • (2012) Wiener Klinische Wochenschrift , vol.124 , pp. 395-402
    • Reiberger, T.1    Ferlitsch, A.2    Payer, B.A.3
  • 20
    • 34848908660 scopus 로고    scopus 로고
    • The use of transient elastometry for assessing liver fibrosis in patients with HIV and hepatitis C virus coin-fection
    • Vergara S, Macias J, Rivero A, et al. The use of transient elastometry for assessing liver fibrosis in patients with HIV and hepatitis C virus coin-fection. Clin Infect Dis 2007;45:969-74.
    • (2007) Clin Infect Dis , vol.45 , pp. 969-974
    • Vergara, S.1    Macias, J.2    Rivero, A.3
  • 21
    • 84890566568 scopus 로고    scopus 로고
    • Revisiting predictors of virologic response to PEGIFN + RBV therapy in HIV-/HCV-coinfected patients: The role of metabolic factors and elevated GGT levels
    • Mandorfer M, Reiberger T, Payer BA, et al. Revisiting predictors of virologic response to PEGIFN + RBV therapy in HIV-/HCV-coinfected patients: the role of metabolic factors and elevated GGT levels. J Viral Hepat 2014;21:33-41.
    • (2014) J Viral Hepat , vol.21 , pp. 33-41
    • Mandorfer, M.1    Reiberger, T.2    Payer, B.A.3
  • 22
    • 84922730255 scopus 로고    scopus 로고
    • Strategies for assignment of HIV/HCV genotype 1-coinfected patients to either dual-therapy or direct-acting antiviral agent based triple therapy
    • Mandorfer M, Neukam K, Rivero A, et al. Strategies for assignment of HIV/HCV genotype 1-coinfected patients to either dual-therapy or direct-acting antiviral agent based triple therapy. Antivir Ther 2014;19:407-14.
    • (2014) Antivir Ther , vol.19 , pp. 407-414
    • Mandorfer, M.1    Neukam, K.2    Rivero, A.3
  • 23
    • 84858706070 scopus 로고    scopus 로고
    • Prediction of response to pegy-lated interferon plus ribavirin in HIV/hepatitis C virus (HCV)-coinfected patients using HCV genotype, IL28B variations, and HCV-RNA load
    • Neukam K, Camacho A, Caruz A, et al. Prediction of response to pegy-lated interferon plus ribavirin in HIV/hepatitis C virus (HCV)-coinfected patients using HCV genotype, IL28B variations, and HCV-RNA load. J Hepatol 2012;56:788-94.
    • (2012) J Hepatol , vol.56 , pp. 788-794
    • Neukam, K.1    Camacho, A.2    Caruz, A.3
  • 24
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011;364:2405-16.
    • (2011) N Engl J Med , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 25
    • 84871231459 scopus 로고    scopus 로고
    • Revisiting the predictors of a sustained virologic response in the era of direct-acting antiviral therapy for hepatitis C virus
    • Beinhardt S, Rutter K, Stattermayer AF, Ferenci P. Revisiting the predictors of a sustained virologic response in the era of direct-acting antiviral therapy for hepatitis C virus. Clin Infect Dis 2013;56:118-22.
    • (2013) Clin Infect Dis , vol.56 , pp. 118-122
    • Beinhardt, S.1    Rutter, K.2    Stattermayer, A.F.3    Ferenci, P.4
  • 26
    • 84865494240 scopus 로고    scopus 로고
    • Factors that predict response of patients with hepatitis C virus infection to boceprevir
    • Poordad F, Bronowicki JP, Gordon SC, et al. Factors that predict response of patients with hepatitis C virus infection to boceprevir. Gastro-enterology 2012;143:608-18.
    • (2012) Gastro-enterology , vol.143 , pp. 608-618
    • Poordad, F.1    Bronowicki, J.P.2    Gordon, S.C.3
  • 27
    • 84878366252 scopus 로고    scopus 로고
    • Pegylated interferon plus ribavirin is suboptimal in IL28B CC carriers without rapid response
    • Neukam K, Barreiro P, Rivero-Juarez A, et al. Pegylated interferon plus ribavirin is suboptimal in IL28B CC carriers without rapid response. J Infect 2013;67:59-64.
    • (2013) J Infect , vol.67 , pp. 59-64
    • Neukam, K.1    Barreiro, P.2    Rivero-Juarez, A.3
  • 28
    • 84899651307 scopus 로고    scopus 로고
    • Peg-inter-feron plus ribavirin with or without boceprevir or telaprevir for HCV genotype 1: A meta-analysis on the role of response predictors
    • Coppola N, Pisaturo M, Sagnelli C, Sagnelli E, Angelillo IF. Peg-inter-feron plus ribavirin with or without boceprevir or telaprevir for HCV genotype 1: a meta-analysis on the role of response predictors. PLOS One 2014;9:e94542.
    • (2014) PLOS One , vol.9 , pp. e94542
    • Coppola, N.1    Pisaturo, M.2    Sagnelli, C.3    Sagnelli, E.4    Angelillo, I.F.5
  • 29
    • 84890115492 scopus 로고    scopus 로고
    • Health-related quality of life and severity of fatigue in HIV/HCV co-infected patients before, during, and after antiviral therapy with pegylated interferon plus ribavirin
    • Mandorfer M, Payer BA, Scheiner B, et al. Health-related quality of life and severity of fatigue in HIV/HCV co-infected patients before, during, and after antiviral therapy with pegylated interferon plus ribavirin. Liver Int 2014;34:69-77.
    • (2014) Liver Int , vol.34 , pp. 69-77
    • Mandorfer, M.1    Payer, B.A.2    Scheiner, B.3
  • 30
    • 84895930592 scopus 로고    scopus 로고
    • Sustained virological response in HIV/HCV co-infected patients treated with pegylated inter-feron/ribavirin can be predicted from the overall rate of viral load decline over the first 4 weeks of therapy
    • Rivero-Juarez A, Neukam K, Labarga P, et al. Sustained virological response in HIV/HCV co-infected patients treated with pegylated inter-feron/ribavirin can be predicted from the overall rate of viral load decline over the first 4 weeks of therapy. J Infect 2014;68:372-7.
    • (2014) J Infect , vol.68 , pp. 372-377
    • Rivero-Juarez, A.1    Neukam, K.2    Labarga, P.3
  • 32
    • 84881313643 scopus 로고    scopus 로고
    • Safety of triple therapy with telaprevir or boceprevir in hepatitis C patients with advanced liver disease-predictive factors for sepsis
    • Rutter K, Ferlitsch A, Maieron A, et al. Safety of triple therapy with telaprevir or boceprevir in hepatitis C patients with advanced liver disease-predictive factors for sepsis. J Hepatol 2013;58:S30.
    • (2013) J Hepatol , vol.58 , pp. S30
    • Rutter, K.1    Ferlitsch, A.2    Maieron, A.3
  • 33
    • 84882908504 scopus 로고    scopus 로고
    • Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC)-NCT01514890
    • Hezode C, Fontaine H, Dorival C, et al. Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC)-NCT01514890. J Hepatol 2013;59:434-41.
    • (2013) J Hepatol , vol.59 , pp. 434-441
    • Hezode, C.1    Fontaine, H.2    Dorival, C.3
  • 34
    • 84862988105 scopus 로고    scopus 로고
    • The risk of infections in HIV-HCV coinfected patients during antiviral therapy with pegIFN-+RBV
    • Payer BA, Reiberger T, Breitenecker F, et al. The risk of infections in HIV-HCV coinfected patients during antiviral therapy with pegIFN-+RBV. J Infect 2012;65:142-9.
    • (2012) J Infect , vol.65 , pp. 142-149
    • Payer, B.A.1    Reiberger, T.2    Breitenecker, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.