Post-acute care use and hospital readmission after sepsis

Annals of the American Thoracic Society

Volumn 12, Issue 6, 2015, Pages 904-913

  Jones, Tiffanie K ^a,b   Fuchs, Barry D ^a,b   Small, Dylan S ^c   Halpern, Scott D ^a,b,c,d   Hanish, Asaf ^c   Umscheid, Craig A ^a,b,c   Baillie, Charles A ^b   Kerlin, Meeta Prasad ^a,b,c   Gaieski, David F ^a   Mikkelsen, Mark E ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Critical care; Emergency department use; Hospital readmission; Infection; Sepsis

Indexed keywords

HEMOGLOBIN;

ADULT; AGE; COHORT ANALYSIS; CONFERENCE PAPER; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; ERYTHROCYTE PARAMETERS; FEMALE; HEALTH CARE SYSTEM; HEALTH CARE UTILIZATION; HEMOGLOBIN BLOOD LEVEL; HOSPICE CARE; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; INTENSIVE CARE; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MEDICAL PROCEDURES; MORBIDITY; MORTALITY; MULTICENTER STUDY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; POST ACUTE CARE; RED CELL DISTRIBUTION WIDTH; RETROSPECTIVE STUDY; RISK FACTOR; SEPSIS; UNITED STATES; UNIVERSITY HOSPITAL; AGED; CLINICAL TRIAL; HOSPITAL DISCHARGE; INSURANCE; MEAN CORPUSCULAR VOLUME; MEDICARE; MIDDLE AGED; NEOPLASMS; PROCEDURES; RISK ASSESSMENT; STATISTICS AND NUMERICAL DATA;

ADULT; AGE FACTORS; AGED; CRITICAL CARE; ERYTHROCYTE INDICES; FEMALE; HEMOGLOBINS; HUMANS; INSURANCE CLAIM REVIEW; MALE; MEDICARE; MIDDLE AGED; NEOPLASMS; PATIENT DISCHARGE; PATIENT READMISSION; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SEPSIS; UNITED STATES;

EID: 84942242297     PISSN: 23296933     EISSN: 23256621     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201411-504OC     Document Type: Conference Paper

References (53)

1. Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med 2013;369:840-851.
2. Gaieski DF, Edwards JM, Kallan MJ, Carr BG. Benchmarking the incidence and mortality of severe sepsis in the United States. Crit Care Med 2013;41:1167-1174.
3. Kaukonen KM, Bailey M, Suzuki S, Pilcher D, Bellomo R. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012. JAMA 2014; 311:1308-1316.
4. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-1377.
5. Jones AE, Shapiro NI, Trzeciak S, Arnold RC, Claremont HA, Kline JA; Emergency Medicine Shock Research Network (EMShockNet) Investigators. Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA 2010;303:739-746.
6. Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, et al.; ProCESS Investigators. A randomized trial of protocol-based care for early septic shock. N Engl J Med 2014;370:1683-1693.
7. Iwashyna TJ, Cooke CR, Wunsch H, Kahn JM. Population burden of long-term survivorship after severe sepsis in older Americans. J Am Geriatr Soc 2012;60:1070-1077.
8. Yende S, Angus DC. Long-term outcomes from sepsis. Curr Infect Dis Rep 2007;9:382-386.
9. Yende S, D'Angelo G, Kellum JA, Weissfeld L, Fine J, Welch RD, Kong L, Carter M, Angus DC; GenIMS Investigators. Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. Am J Respir Crit CareMed 2008;177:1242-1247.
10. Iwashyna TJ, Ely EW, Smith DM, Langa KM. Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA 2010;304:1787-1794.
11. Unroe M, Kahn JM, Carson SS, Govert JA, Martinu T, Sathy SJ, Clay AS, Chia J, Gray A, Tulsky JA, et al. One-year trajectories of care and resource utilization for recipients of prolonged mechanical ventilation: a cohort study. Ann Intern Med 2010; 153:167-175.
12. Mechanic R. Post-acute care-the next frontier for controlling Medicare spending. N Engl J Med 2014;370:692-694.
13. Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med 2009; 360:1418-1428. [Published erratum appears in N Engl J Med 2011; 364:1582.].
14. Elixhauser A, Steiner C. Readmissions to US hospital by diagnosis, 2010. Statistical Brief #161. Rockville, MD: Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality; April 2013 [accessed 2015 Mar 19]. Available from: http://www.hcup-us. ahrq.gov/reports/statbriefs/sb153.pdf.
15. Liu V, Lei X, Prescott HC, Kipnis P, Iwashyna TJ, Escobar GJ. Hospital readmission and healthcare utilization following sepsis in community settings. J Hosp Med 2014;9:502-507.
16. Prescott HC, Langa KM, Liu V, Escobar GJ, Iwashyna TJ. Increased 1-year healthcare use in survivors of severe sepsis. Am J Respir Crit Care Med 2014;190:62-69.
17. Ortego A, Gaieski DF, Fuchs BD, Jones T, Halpern SD, Small DS, Sante SC, Drumheller B, Christie JD, Mikkelsen ME. Hospital-based acute care use in survivors of septic shock. Crit Care Med 2015; 43:729-737.
18. Whittaker SA, Mikkelsen ME, Gaieski DF, Koshy S, Kean C, Fuchs BD. Severe sepsis cohorts derived from claims-based strategies appear to be biased toward a more severely ill patient population. Crit Care Med 2013;41:945-953.
19. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29:1303-1310.
20. Iwashyna TJ, Odden A, Rohde J, Bonham C, Kuhn L, Malani P, Chen L, Flanders S. Identifying patients with severe sepsis using administrative claims: patient-level validation of the Angus implementation of the international consensus conference definition of severe sepsis. Med Care 2014;52:e39-e43.
21. Baillie CA, VanZandbergen C, Tait G, Hanish A, Leas B, French B, Hanson CW, Behta M, Umscheid CA. The readmission risk flag: using the electronic health record to automatically identify patients at risk for 30-day readmission. J Hosp Med 2013;8:689-695.
22. Dharmarajan K, Hsieh AF, Lin Z, Bueno H, Ross JS, Horwitz LI, Barreto-Filho JA, Kim N, Bernheim SM, Suter LG, et al. Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia. JAMA 2013;309:355-363.
23. Vashi AA, Fox JP, Carr BG, D'Onofrio G, Pines JM, Ross JS, Gross CP. Use of hospital-based acute care among patients recently discharged from the hospital. JAMA 2013;309:364-371.
24. DonzéJ, Aujesky D, Williams D, Schnipper JL. Potentially avoidable 30-day hospital readmissions in medical patients: derivation and validation of a prediction model. JAMA Intern Med 2013;173: 632-638.
25. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-383.
26. Maldonado G, Greenland S. Simulation study of confounder-selection strategies. Am J Epidemiol 1993;138:923-936.
27. Barnato AE, Albert SM, Angus DC, Lave JR, Degenholtz HB. Disability among elderly survivors of mechanical ventilation. Am J Respir Crit Care Med 2011;183:1037-1042.
28. Guerra C, Linde-Zwirble WT, Wunsch H. Risk factors for dementia after critical illness in elderly Medicare beneficiaries. Crit Care 2012;16:R233.
29. Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, et al.; BRAIN-ICU Study Investigators. Long-term cognitive impairment after critical illness. N Engl J Med 2013;369:1306-1316.
30. Hunziker S, Celi LA, Lee J, Howell MD. Red cell distribution width improves the simplified acute physiology score for risk prediction in unselected critically ill patients. Crit Care 2012;16:R89.
31. Purtle SW, Moromizato T, McKane CK, Gibbons FK, Christopher KB. The association of red cell distribution width at hospital discharge and out-of-hospital mortality following critical illness. Crit Care Med 2014;42:918-929.
32. Liu V, Escobar GJ, Greene JD, Soule J, Whippy A, Angus DC, Iwashyna TJ. Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA 2014;312:90-92.
33. de Gonzalo-Calvo D, de Luxán-Delgado B, Rodríguez-González S, García-Macia M, Suárez FM, Solano JJ, Rodríguez-Colunga MJ, Coto-Montes A. Interleukin 6, soluble tumor necrosis factor receptor I and red blood cell distribution width as biological markers of functional dependence in an elderly population: a translational approach. Cytokine 2012;58:193-198.
34. Cooke CR, Iwashyna TJ. Sepsis mandates: improving inpatient care while advancing quality improvement. JAMA 2014;312:1397-1398.
35. Lindenauer PK, Lagu T, Shieh MS, Pekow PS, Rothberg MB. Association of diagnostic coding with trends in hospitalizations and mortality of patients with pneumonia, 2003-2009. JAMA 2012; 307:1405-1413.
36. Rothberg MB, Pekow PS, Priya A, Lindenauer PK. Variation in diagnostic coding of patients with pneumonia and its association with hospital risk-standardized mortality rates: a cross-sectional analysis. Ann Intern Med 2014;160:380-388.
37. Walton AH, Muenzer JT, Rasche D, Boomer JS, Sato B, Brownstein BH, Pachot A, Brooks TL, Deych E, Shannon WD, et al. Reactivation of multiple viruses in patients with sepsis. PLoS One 2014;9:e98819.
38. Wang T, Derhovanessian A, De Cruz S, Belperio JA, Deng JC, Hoo GS. Subsequent infections in survivors of sepsis: epidemiology and outcomes. J Intensive Care Med 2014;29:87-95.
39. Sutton JP, Friedman B. Trends in septicemia hospitalizations and readmissions in selected HCUP states, 2005 and 2010. Statistical Brief #161. Rockville, MD: Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality; September 2013 [accessed 2015 Mar 19]. Available from: http://www.hcup-us.ahrq.gov/reports/statbriefs/sb161.pdf.
40. Rohde JM, Dimcheff DE, Blumberg N, Saint S, Langa KM, Kuhn L, Hickner A, Rogers MA. Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis. JAMA 2014;311:1317-1326.
41. Lavenberg JG, Leas B, Umscheid CA, Williams K, Goldmann DR, Kripalani S. Assessing preventability in the quest to reduce hospital readmissions. J Hosp Med 2014;9:598-603.
42. Hansen LO, Young RS, Hinami K, Leung A, Williams MV. Interventions to reduce 30-day rehospitalization: a systematic review. Ann Intern Med 2011;155:520-528.
43. Chastre J, Wolff M, Fagon JY, Chevret S, Thomas F, Wermert D, Clementi E, Gonzalez J, Jusserand D, Asfar P, et al.; PneumA Trial Group. Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial. JAMA 2003;290:2588-2598.
44. Keller SC, Ciuffetelli D, Bilker W, Norris A, Timko D, Rosen A, Myers JS, Hines J, Metlay J. The impact of an infectious diseases transition service on the care of outpatients on parenteral antimicrobial therapy. J Pharm Technol 2013;29:205-214.
45. Kvedar J, Coye MJ, Everett W. Connected health: a review of technologies and strategies to improve patient care with telemedicine and telehealth. Health Aff (Millwood) 2014;33:194-199.
46. Burke RE, Juarez-Colunga E, Levy C, Prochazka AV, Coleman EA, Ginde AA. Rise of post-acute care facilities as a discharge destination of US hospitalizations. JAMA Intern Med 2015;175: 295-296.
47. Chao PW, Shih CJ, Lee YJ, Tseng CM, Kuo SC, Shih YN, Chou KT, Tarng DC, Li SY, Ou SM, et al. Association of postdischarge rehabilitation with mortality in intensive care unit survivors of sepsis. Am J Respir Crit Care Med 2014;190:1003-1011.
48. Sochalski J, Jaarsma T, Krumholz HM, Laramee A, McMurray JJV, Naylor MD, Rich MW, Riegel B, Stewart S. What works in chronic care management: the case of heart failure. Health Aff (Millwood) 2009;28:179-189.
49. Hernandez AF, Greiner MA, Fonarow GC, Hammill BG, Heidenreich PA, Yancy CW, Peterson ED, Curtis LH. Relationship between early physician follow-up and 30-day readmission among Medicare beneficiaries hospitalized for heart failure. JAMA 2010; 303:1716-1722.
50. Bowles KH, Ratcliffe SJ, Holmes JH, Liberatore M, Nydick R, Naylor MD. Post-acute referral decisions made by multidisciplinary experts compared to hospital clinicians and the patients' 12-week outcomes. Med Care 2008;46:158-166.
51. Bowles KH, Hanlon A, Holland D, Potashnik SL, Topaz M. Impact of discharge planning decision support on time to readmission among older adult medical patients. Prof Case Manag 2014;19:29-38.
52. Iwashyna TJ, Netzer G, Langa KM, Cigolle C. Spurious inferences about long-term outcomes: the case of severe sepsis and geriatric conditions. Am J Respir Crit Care Med 2012;185:835-841.
53. Stuart EA. Matching methods for causal inference: a review and a look forward. Stat Sci 2010;25:1-21.