MiR-155 and miR-146b negatively regulates IL6 in Helicobacter pylori (cagA+) infected gastroduodenal ulcer

European Review for Medical and Pharmacological Sciences

Volumn 19, Issue 4, 2015, Pages 607-613

  Cheng, S F ^a   Li, L ^a   Wang, L M ^a  

^a THE SECOND AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Gastroduodenal ulcer; Gene IL6; H. pylori; MiR 146b; MiR 155

Indexed keywords

CAGA PROTEIN; INTERLEUKIN 6; MICRORNA; MICRORNA 146B; MICRORNA 155; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CAGA PROTEIN, HELICOBACTER PYLORI; IL6 PROTEIN, HUMAN; MIRN146 MICRORNA, HUMAN; MIRN155 MICRORNA, HUMAN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DUODENUM BIOPSY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; PEPTIC ULCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH EPITHELIUM; UPREGULATION; WESTERN BLOTTING; CASE CONTROL STUDY; CELL CULTURE; COMPLICATION; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CASE-CONTROL STUDIES; CELLS, CULTURED; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTERLEUKIN-6; MICRORNAS; PEPTIC ULCER;

EID: 84942241420     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. FIGURA N. Identifiable Helicobacter pylori strains or factors important in the development of duodenal ulcer disease. Helicobacter 1997; 2 Suppl 1: S3-12
2. SUZUKI R, SHIOTA S, YAMAOKA Y. Molecular epidemiology, population genetics, and pathogenic role of Helicobacter pylori. Infect Genet Evol 2012; 12: 203-213
3. DI RIENZO TA, D'ANGELO G, OJETTI V, CAMPANALE MC, TORTORA A, CESARIO V, Z UCCALA G, FRANCESCHI F. 13CUrea breath test for the diagnosis of Helicobacter pylori infection. Eur Rev Med Pharmacol Sci 2013; 17 Suppl 2: 51-58
4. SUZUKI H, IWASAKI E AND HIBI T. Helicobacter pylori and gastric cancer.Gastric Cancer 2009; 12: 79-87
5. WROBLEWSKI LE, PEEK RM JR, WILSON KT. Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev 2010; 23: 713-739
6. DHAR SK, SONI RK, DAS BK, MUKHOPADHYAY G. Molecular mechanism of action of major Helicobacter pylori virulence factors. Mol Cell Biochem 2003; 253: 207-215
7. COMPARE D, RO CCO A, NARDONE G. Risk factors in gastric cancer. Eur Rev Med Pharmacol Sci 2010; 14: 302-308
8. ATESHKADI A, LAM NP, JOHNSON CA. Helicobacter pylori and peptic ulcer disease. Clin Pharm 1993; 12: 34-48
9. BARTEL DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233
10. NOTO JM, PEEK RM. The role of microRNAs in Helicobacter pylori pathogenesis and gastric carcinogenesis. Front Cell Infect Microbiol 2011; 1: 21
11. KLOOSTERMAN WP, PLASTERK RH. The diverse functions of microRNAs in animal development and disease. Dev Cell 2006; 11: 441-450
12. LU J, GETZ G, MISKA EA, ALVAREZ-SAAVEDRA E, LAMB J, PECK D, SWEET-CORDERO A, EBERT BL, MAK RH, FERRANDO AA, DOWNING JR, JACKS T, H ORVITZ HR, GOLUB TR. MicroRNA expression profiles classify human cancers. Nature 2005; 435: 834-838
13. SUN EH, ZHOU Q, LIU KS, WEI W, WANG CM, LIU XF, LU C, MA DY. Scree ning miRNAs related to different subtypes of breast cancer with miRNAs microarray. Eur Rev Med Pharmacol Sci 2014; 18: 2783-2788
14. SONKOLY E, PIVARCSI A. Advances in microRNAs: implications for immunity and inflammatory diseases. J Cell Mol Med 2009; 13: 24-38
15. WU F,ZIKUSOKA M,TRINDADE A,DASSOPOULOS T,HARRIS ML,BAYLESS TM,BRANT SR,CHAKRAVARTI S,KWON JH. MicroRNA s are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha Gastroenterology 2008 135 1624-1635 e1624
16. NISHIZAWA T, SUZUKI H. The Role of microRNA in Gastric Malignancy. Int J Mol Sci 2013; 14: 9487-9496
17. BLASER MJ, BERG DE. Helicobacter pylori genetic diversity and risk of human disease. J Clin Invest 2001; 107: 767-773
18. XIAO B, LIU Z, LI BS, TANG B, LI W, GUO G, SHI Y, WANG F, WU Y, TONG WD, GUO H, MAO XH AND ZOU QM. Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response. J Infect Dis 2009; 200: 916-925
19. SHI C, ZHU L, CHEN X, GU N, C HEN L, ZHU L, YANG L, PANG L, GUO X, JI C, ZHANG C. IL-6 and TNF-Alpha induced obesity-related inflammatory response through transcriptional regulation of miR-146b. J Interferon Cytokine Res 2014; 34: 342-348
20. KANG JM, KIM N, LEE DH, PARK JH, LEE MK, KIM JS, JUNG HC, SONG IS. The effects of genetic polymorphisms of IL-6, IL-8, and IL-10 on Helicobacter pylori-induced gastroduodenal diseases in Korea . J Clin Gastroenterol 2009; 43: 420-428
21. BLASER MJ. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis 1990; 161: 626-633