Sepsis-associated outcomes in critically ill patients with malignancies

Annals of the American Thoracic Society

Volumn 12, Issue 8, 2015, Pages 1185-1192

  Torres, Viviane B L ^a   Azevedo, Luciano C P ^b,c   Silva, Ulysses V A ^d   Caruso, Pedro ^e   Torelly, André P ^f   Silva, Eliezer ^g   Carvalho, Frederico B ^h   Vianna, Arthur ⁱ   Souza, Paulo C P ^j   Godoy, Michele M G ^k   Azevedo, José R A ^l   Spector, Nelson ^a   Bozza, Fernando A ^i,m   Salluh, Jorge I F ^a,b,i   Soares, Marcio ^a,b,i  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^c Education and Research Center Siacute rio Libanês Hospital   (Brazil)

^d BARRETOS CANCER HOSPITAL   (Brazil)

^e A C CAMARGO CANCER CENTER   (Brazil)

^f Irmandade da Santa Casa de Miserico rdia de Porto Alegre   (Brazil)

^g HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^h Hospital Mater Dei SA   (Brazil)

ⁱ INSTITUTO OSWALDO CRUZ   (Brazil)

^j Hospital de Clinicas de Niteroi   (Brazil)

^k FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^l ICU Hospital São Domingos São Lúis   (Brazil)

^m Funda??o Oswaldo Cruz   (Brazil)

more..

Author keywords

Cancer; Infection; Intensive care; Malignancy; Sepsis

Indexed keywords

ABDOMINAL INFECTION; ADULT; ARTICLE; BLOODSTREAM INFECTION; BRAZILIAN; CANCER MORTALITY; CANCER PATIENT; CANCER PROGNOSIS; COHORT ANALYSIS; CRITICALLY ILL PATIENT; FEMALE; HEMATOLOGIC MALIGNANCY; HUMAN; INTENSIVE CARE UNIT; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PROSPECTIVE STUDY; RISK FACTOR; SEPSIS; SEPTIC SHOCK; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SIMPLIFIED ACUTE PHYSIOLOGY SCORE; URINARY TRACT INFECTION; AGED; BRAZIL; CLINICAL TRIAL; COMPLICATION; CRITICAL ILLNESS; HOSPITAL MORTALITY; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; NEOPLASM; ODDS RATIO; PROGNOSIS; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; STATISTICAL MODEL; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BRAZIL; CRITICAL ILLNESS; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE UNITS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASMS; ODDS RATIO; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC;

EID: 84942241271     PISSN: 23296933     EISSN: 23256621     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201501-046OC     Document Type: Article

References (31)

1. Rosolem MM, Rabello LS, Lisboa T, Caruso P, Costa RT, Leal JV, Salluh JI, Soares M. Critically ill patients with cancer and sepsis: Clinical course and prognostic factors. J Crit Care 2012; 27: 301-307.
2. Danai PA, Moss M, Mannino DM, Martin GS. The epidemiology of sepsis in patients with malignancy. Chest 2006; 129: 1432-1440.
3. Soares M, Lisboa T. Caring for cancer patients with severe sepsis: The more I see, the more I know, the less I understand.... Crit Care Med 2012; 40: 308-310.
4. Soares M, Caruso P, Silva E, Teles JM, Lobo SM, Friedman G, Dal Pizzol F, Mello PV, Bozza FA, Silva UV, et al.; Brazilian Research in Intensive Care Network (BRICNet). Characteristics and outcomes of patients with cancer requiring admission to intensive care units: A prospective multicenter study. Crit Care Med 2010; 38: 9-15.
5. Williams MD, Braun LA, Cooper LM, Johnston J, Weiss RV, Qualy RL, Linde-Zwirble W. Hospitalized cancer patients with severe sepsis: Analysis of incidence, mortality, and associated costs of care. Crit Care 2004; 8: R291-R298.
6. Soares M, Salluh JI. Advanced supportive care for patients with cancer in Latin America. Lancet Oncol 2013; 14: E337.
7. Bozza FA, Salluh JI. An urban perspective on sepsis in developing countries. Lancet Infect Dis 2010; 10: 290-291.
8. Azevedo LC, Caruso P, Silva UV, Torelly AP, Silva E, Rezende E, Netto JJ, Piras C, Lobo SM, Knibel MF, et al. Outcomes for patients with cancer admitted to the ICU requiring ventilatory support: Results from a prospective multicenter study. Chest 2014; 146: 257-266.
9. Taccone FS, Artigas AA, Sprung CL, Moreno R, Sakr Y, Vincent JL. Characteristics and outcomes of cancer patients in European ICUs. Crit Care 2009; 13: R15.
10. Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, Moreno R, Carlet J, Le Gall JR, Payen D; Sepsis Occurrence in Acutely Ill Patients Investigators. Sepsis in European intensive care units: Results of the SOAP study. Crit Care Med 2006; 34: 344-353.
11. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G; SCCM/ESICM/ACCP/ATS/SIS. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003; 31: 1250-1256.
12. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG; Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 1996; 22: 707-710.
13. Moreno RP, Metnitz PG, Almeida E, Jordan B, Bauer P, Campos RA, Iapichino G, Edbrooke D, Capuzzo M, Le Gall JR Jr; SAPS 3 Investigators. SAPS 3-From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission. Intensive Care Med 2005; 31: 1345-1355.
14. Kallogjeri D, Piccirillo JF, Spitznagel EL Jr, Steyerberg EW. Comparison of scoring methods for ACE-27: Simpler is better. J Geriatr Oncol 2012; 3: 238-245.
15. Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: Results of a multicenter, prospective study. Crit Care Med 1998; 26: 1793-1800.
16. Zubrod CG, Schneiderman M, Frei E III, Brindley C, Gold GL, Shnider B, Oviedo R, Gorman J, Jones R Jr, Jonsson U, et al.; Eastern Cooperative Group in Solid Tumor Chemotherapy USA. Appraisal of methods for the study of chemotherapy of cancer in man: Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide. J Chronic Dis 1960; 11: 7-33.
17. Hosmer DW, Lemeshow S. Applied logistic regression, 2nd ed. New York: Wiley-Interscience; 2000.
18. de Montmollin E, Tandjaoui-Lambiotte Y, Legrand M, Lambert J, Mokart D, Kouatchet A, Lemiale V, Pè ne F, Bruneel F, Vincent F, et al. Outcomes in critically ill cancer patients with septic shock of pulmonary origin. Shock 2013; 39: 250-254.
19. Aygencel G, Turkoglu M, Turkoz Sucak G, Benekli M. Prognostic factors in critically ill cancer patients admitted to the intensive care unit. J Crit Care 2014; 29: 618-626.
20. Azoulay E, Soares M, Darmon M, Benoit D, Pastores S, Afessa B. Intensive care of the cancer patient: Recent achievements and remaining challenges. Ann Intensive Care 2011; 1: 5.
21. Song JU, Suh GY, Park HY, Lim SY, Han SG, Kang YR, Kwon OJ, Woo S, Jeon K. Early intervention on the outcomes in critically ill cancer patients admitted to intensive care units. Intensive Care Med 2012; 38: 1505-1513.
22. Khassawneh BY, White P Jr, Anaissie EJ, Barlogie B, Hiller FC. Outcome from mechanical ventilation after autologous peripheral blood stem cell transplantation. Chest 2002; 121: 185-188.
23. Legrand M, Max A, Peigne V, Mariotte E, Canet E, Debrumetz A, Lemiale V, Seguin A, Darmon M, Schlemmer B, et al. Survival in neutropenic patients with severe sepsis or septic shock. Crit Care Med 2012; 40: 43-49.
24. Larché J, Azoulay E, Fieux F, Mesnard L, Moreau D, Thiery G, Darmon M, Le Gall JR, Schlemmer B. Improved survival of critically ill cancer patients with septic shock. Intensive Care Med 2003; 29: 1688-1695.
25. Azoulay E, Mokart D, Pè ne F, Lambert J, Kouatchet A, Mayaux J, Vincent F, Nyunga M, Bruneel F, Laisne LM, et al. Outcomes of critically ill patients with hematologic malignancies: Prospective multicenter data from France and Belgium-A groupe de recherche respiratoire en réanimation onco-hématologique study. J Clin Oncol 2013; 31: 2810-2818.
26. Yadegarynia D, Tarrand J, Raad I, Rolston K. Current spectrum of bacterial infections in patients with cancer. Clin Infect Dis 2003; 37: 1144-1145.
27. Wisplinghoff H, Seifert H, Wenzel RP, Edmond MB. Current trends in the epidemiology of nosocomial bloodstream infections in patients with hematological malignancies and solid neoplasms in hospitals in the United States. Clin Infect Dis 2003; 36: 1103-1110.
28. Rolston KV. Challenges in the treatment of infections caused by grampositive and gram-negative bacteria in patients with cancer and neutropenia. Clin Infect Dis 2005; 40 Suppl 4: S246-S252.
29. McKenzie FE. Case mortality in polymicrobial bloodstream infections. J Clin Epidemiol 2006; 59: 760-761.
30. Elting LS, Bodey GP, Fainstein V. Polymicrobial septicemia in the cancer patient. Medicine (Baltimore) 1986; 65: 218-225.
31. Marin M, Gudiol C, Ardanuy C, Garcia-Vidal C, Calvo M, Arnan M, Carratalà J. Bloodstream infections in neutropenic patients with cancer: Differences between patients with haematological malignancies and solid tumours. J Infect 2014; 69: 417-423.