Antidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial

Diabetologia

Volumn 58, Issue 10, 2015, Pages 2336-2343

  Wasko, Mary Chester M ^a   McClure, Candace K ^b   Kelsey, Sheryl F ^b   Huber, Kimberly ^c   Orchard, Trevor ^b   Toledo, Frederico G S ^c  

^a ALLEGHENY HEALTH NETWORK   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Beta cell function; Hydroxychloroquine; Insulin sensitivity

Indexed keywords

ADIPONECTIN; HEMOGLOBIN A1C; HYDROXYCHLOROQUINE; INSULIN; INTERLEUKIN 1; INTERLEUKIN 6; PLACEBO; CYTOKINE; GLUCOSE BLOOD LEVEL; INTERCELLULAR ADHESION MOLECULE 1;

ADULT; ANTIDIABETIC ACTIVITY; ARTICLE; CELL ADHESION; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; NATIONAL HEALTH ORGANIZATION; OBESITY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RHEUMATIC DISEASE; TREATMENT DURATION; BLOOD; DOUBLE BLIND PROCEDURE; DRUG EFFECTS; METABOLISM; MIDDLE AGED; PANCREAS ISLET BETA CELL; PHYSIOLOGY; TREATMENT OUTCOME;

ADULT; BLOOD GLUCOSE; CYTOKINES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYDROXYCHLOROQUINE; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; TREATMENT OUTCOME;

EID: 84942198542     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3689-2     Document Type: Article

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