-
1
-
-
0003859843
-
-
July 2015, posting date. World Health Organization, Geneva, Switzerland
-
World Health Organization. July 2015, posting date. Hepatitis B fact sheet. World Health Organization, Geneva, Switzerland. http://www.who.int/mediacentre/factsheets/fs204/en/.
-
Hepatitis B fact sheet
-
-
-
2
-
-
84895072870
-
New therapeutic vaccination strategies for the treatment of chronic hepatitis B
-
Liu J, Kosinska A, Lu M, Roggendorf M. 2014. New therapeutic vaccination strategies for the treatment of chronic hepatitis B. Virol Sin 29:10-16. http://dx.doi.org/10.1007/s12250-014-3410-5.
-
(2014)
Virol Sin
, vol.29
, pp. 10-16
-
-
Liu, J.1
Kosinska, A.2
Lu, M.3
Roggendorf, M.4
-
3
-
-
17344369213
-
Genetic immunization of chimpanzees chronically infected with the hepatitis B virus, using a recombinant retroviral vector encoding the hepatitis B virus core antigen
-
Sällberg M, Hughes J, Javadian A, Ronlov G, Hultgren C, Townsend K, Anderson CG, O'Dea J, Alfonso J, Eason R, Murthy KK, Jolly DJ, Chang SM, Mento SJ, Milich D, Lee WT. 1998. Genetic immunization of chimpanzees chronically infected with the hepatitis B virus, using a recombinant retroviral vector encoding the hepatitis B virus core antigen. Hum Gene Ther 9:1719-1729. http://dx.doi.org/10.1089/hum.1998.9.12-1719.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1719-1729
-
-
Sällberg, M.1
Hughes, J.2
Javadian, A.3
Ronlov, G.4
Hultgren, C.5
Townsend, K.6
Anderson, C.G.7
O'Dea, J.8
Alfonso, J.9
Eason, R.10
Murthy, K.K.11
Jolly, D.J.12
Chang, S.M.13
Mento, S.J.14
Milich, D.15
Lee, W.T.16
-
4
-
-
84879549459
-
Combination of DNA prime-adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model
-
Kosinska AD, Zhang E, Johrden L, Liu J, Seiz PL, Zhang X, Ma Z, Kemper T, Fiedler M, Glebe D, Wildner O, Dittmer U, Lu M, Roggendorf M. 2013. Combination of DNA prime-adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model. PLoS Pathog 9:e1003391. http://dx.doi.org/10.1371/journal.ppat.1003391.
-
(2013)
PLoS Pathog
, vol.9
-
-
Kosinska, A.D.1
Zhang, E.2
Johrden, L.3
Liu, J.4
Seiz, P.L.5
Zhang, X.6
Ma, Z.7
Kemper, T.8
Fiedler, M.9
Glebe, D.10
Wildner, O.11
Dittmer, U.12
Lu, M.13
Roggendorf, M.14
-
5
-
-
84938109131
-
TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice
-
26 November 2014
-
Martin P, Dubois C, Jacquier E, Dion S, Mancini-Bourgine M, Godon O, Kratzer R, Lelu-Santolaria K, Evlachev A, Meritet JF, Schlesinger Y, Villeval D, Strub JM, Van Dorsselaer A, Marchand JB, Geist M, Brandely R, Findeli A, Boukhebza H, Menguy T, Silvestre N, Michel ML, Inchauspe G. 26 November 2014. TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice. Gut http://dx.doi.org/10.1136/gutjnl-2014-308041.
-
Gut
-
-
Martin, P.1
Dubois, C.2
Jacquier, E.3
Dion, S.4
Mancini-Bourgine, M.5
Godon, O.6
Kratzer, R.7
Lelu-Santolaria, K.8
Evlachev, A.9
Meritet, J.F.10
Schlesinger, Y.11
Villeval, D.12
Strub, J.M.13
Van Dorsselaer, A.14
Marchand, J.B.15
Geist, M.16
Brandely, R.17
Findeli, A.18
Boukhebza, H.19
Menguy, T.20
Silvestre, N.21
Michel, M.L.22
Inchauspe, G.23
more..
-
6
-
-
84874727114
-
A vesicular stomatitis virusbased therapeutic vaccine generates a functional CD8 T cell response to hepatitis B virus in transgenic mice
-
Cobleigh MA, Wei X, Robek MD. 2013. A vesicular stomatitis virusbased therapeutic vaccine generates a functional CD8 T cell response to hepatitis B virus in transgenic mice. J Virol 87:2969-2973. http://dx.doi.org/10.1128/JVI.02111-12.
-
(2013)
J Virol
, vol.87
, pp. 2969-2973
-
-
Cobleigh, M.A.1
Wei, X.2
Robek, M.D.3
-
7
-
-
44449112674
-
Hybrid alphavirus-rhabdovirus propagating replicon particles are versatile and potent vaccine vectors
-
Rose NF, Publicover J, Chattopadhyay A, Rose JK. 2008. Hybrid alphavirus-rhabdovirus propagating replicon particles are versatile and potent vaccine vectors. Proc Natl Acad Sci U S A 105:5839-5843. http://dx.doi.org/10.1073/pnas.0800280105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5839-5843
-
-
Rose, N.F.1
Publicover, J.2
Chattopadhyay, A.3
Rose, J.K.4
-
8
-
-
79958083876
-
Significant protection against high-dose simian immunodeficiency virus challenge conferred by a new prime-boost vaccine regimen
-
Schell JB, Rose NF, Bahl K, Diller K, Buonocore L, Hunter M, Marx PA, Gambhira R, Tang H, Montefiori DC, Johnson WE, Rose JK. 2011. Significant protection against high-dose simian immunodeficiency virus challenge conferred by a new prime-boost vaccine regimen. J Virol 85: 5764-5772. http://dx.doi.org/10.1128/JVI.00342-11.
-
(2011)
J Virol
, vol.85
, pp. 5764-5772
-
-
Schell, J.B.1
Rose, N.F.2
Bahl, K.3
Diller, K.4
Buonocore, L.5
Hunter, M.6
Marx, P.A.7
Gambhira, R.8
Tang, H.9
Montefiori, D.C.10
Johnson, W.E.11
Rose, J.K.12
-
9
-
-
77954505687
-
Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest virus replication complexes from the plasma membrane to modified lysosomes
-
Spuul P, Balistreri G, Kaariainen L, Ahola T. 2010. Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest virus replication complexes from the plasma membrane to modified lysosomes. J Virol 84:7543-7557. http://dx.doi.org/10.1128/JVI.00477-10.
-
(2010)
J Virol
, vol.84
, pp. 7543-7557
-
-
Spuul, P.1
Balistreri, G.2
Kaariainen, L.3
Ahola, T.4
-
10
-
-
0027986768
-
Novel infectious particles generated by expression of the vesicular stomatitis virus glycoprotein from a self-replicating RNA
-
Rolls MM, Webster P, Balba NH, Rose JK. 1994. Novel infectious particles generated by expression of the vesicular stomatitis virus glycoprotein from a self-replicating RNA. Cell 79:497-506. http://dx.doi.org/10.1016/0092-8674(94)90258-5.
-
(1994)
Cell
, vol.79
, pp. 497-506
-
-
Rolls, M.M.1
Webster, P.2
Balba, N.H.3
Rose, J.K.4
-
11
-
-
84912050138
-
In vitro evolution of high-titer, virus-like vesicles containing a single structural protein
-
Rose NF, Buonocore L, Schell JB, Chattopadhyay A, Bahl K, Liu X, Rose JK. 2014. In vitro evolution of high-titer, virus-like vesicles containing a single structural protein. Proc Natl Acad SciUSA111:16866-16871. http://dx.doi.org/10.1073/pnas.1414991111.
-
(2014)
Proc Natl Acad SciUSA
, vol.111
, pp. 16866-16871
-
-
Rose, N.F.1
Buonocore, L.2
Schell, J.B.3
Chattopadhyay, A.4
Bahl, K.5
Liu, X.6
Rose, J.K.7
-
12
-
-
0030013730
-
Expression of additional genes in a vector derived from a minimal RNA virus
-
Rolls MM, Haglund K, Rose JK. 1996. Expression of additional genes in a vector derived from a minimal RNA virus. Virology 218:406-411. http://dx.doi.org/10.1006/viro.1996.0211.
-
(1996)
Virology
, vol.218
, pp. 406-411
-
-
Rolls, M.M.1
Haglund, K.2
Rose, J.K.3
-
13
-
-
46149120568
-
Site-specific release of nascent chains from ribosomes at a sense codon
-
Doronina VA, Wu C, de Felipe P, Sachs MS, Ryan MD, Brown JD. 2008. Site-specific release of nascent chains from ribosomes at a sense codon. Mol Cell Biol 28:4227-4239. http://dx.doi.org/10.1128/MCB.00421-08.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4227-4239
-
-
Doronina, V.A.1
Wu, C.2
de Felipe, P.3
Sachs, M.S.4
Ryan, M.D.5
Brown, J.D.6
-
14
-
-
77954522700
-
A vesicular stomatitis virus-based hepatitis B virus vaccine vector provides protection against challenge in a single dose
-
Cobleigh MA, Buonocore L, Uprichard SL, Rose JK, Robek MD. 2010. A vesicular stomatitis virus-based hepatitis B virus vaccine vector provides protection against challenge in a single dose. J Virol 84:7513-7522. http://dx.doi.org/10.1128/JVI.00200-10.
-
(2010)
J Virol
, vol.84
, pp. 7513-7522
-
-
Cobleigh, M.A.1
Buonocore, L.2
Uprichard, S.L.3
Rose, J.K.4
Robek, M.D.5
-
15
-
-
0029130068
-
High-level hepatitis B virus replication in transgenic mice
-
Guidotti LG, Matzke B, Schaller H, Chisari FV. 1995. High-level hepatitis B virus replication in transgenic mice. J Virol 69:6158-6169.
-
(1995)
J Virol
, vol.69
, pp. 6158-6169
-
-
Guidotti, L.G.1
Matzke, B.2
Schaller, H.3
Chisari, F.V.4
-
16
-
-
0037108818
-
Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection
-
Yang PL, Althage A, Chung J, Chisari FV. 2002. Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proc Natl Acad Sci U S A 99:13825-13830. http://dx.doi.org/10.1073/pnas.202398599.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13825-13830
-
-
Yang, P.L.1
Althage, A.2
Chung, J.3
Chisari, F.V.4
-
17
-
-
0025719119
-
Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen
-
Penna A, Chisari FV, Bertoletti A, Missale G, Fowler P, Giuberti T, Fiaccadori F, Ferrari C. 1991. Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen. J Exp Med 174:1565-1570. http://dx.doi.org/10.1084/jem.174.6.1565.
-
(1991)
J Exp Med
, vol.174
, pp. 1565-1570
-
-
Penna, A.1
Chisari, F.V.2
Bertoletti, A.3
Missale, G.4
Fowler, P.5
Giuberti, T.6
Fiaccadori, F.7
Ferrari, C.8
-
18
-
-
0027297761
-
HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection
-
Nayersina R, Fowler P, Guilhot S, Missale G, Cerny A, Schlicht HJ, Vitiello A, Chesnut R, Person JL, Redeker AG, Chisari FV. 1993. HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection. J Immunol 150:4659-4671.
-
(1993)
J Immunol
, vol.150
, pp. 4659-4671
-
-
Nayersina, R.1
Fowler, P.2
Guilhot, S.3
Missale, G.4
Cerny, A.5
Schlicht, H.J.6
Vitiello, A.7
Chesnut, R.8
Person, J.L.9
Redeker, A.G.10
Chisari, F.V.11
-
19
-
-
0034953906
-
Identification of hepatitis B virus-specific CTL epitopes presented by HLA-A*2402, the most common HLA class I allele in East Asia
-
Sobao Y, Sugi K, Tomiyama H, Saito S, Fujiyama S, Morimoto M, Hasuike S, Tsubouchi H, Tanaka K, Takiguch M. 2001. Identification of hepatitis B virus-specific CTL epitopes presented by HLA-A*2402, the most common HLA class I allele in East Asia. J Hepatol 34:922-929. http://dx.doi.org/10.1016/S0168-8278(01)00048-4.
-
(2001)
J Hepatol
, vol.34
, pp. 922-929
-
-
Sobao, Y.1
Sugi, K.2
Tomiyama, H.3
Saito, S.4
Fujiyama, S.5
Morimoto, M.6
Hasuike, S.7
Tsubouchi, H.8
Tanaka, K.9
Takiguch, M.10
-
20
-
-
0036337681
-
Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections
-
Kakimi K, Isogawa M, Chung J, Sette A, Chisari FV. 2002. Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections. J Virol 76:8609-8620. http://dx.doi.org/10.1128/JVI.76.17.8609-8620.2002.
-
(2002)
J Virol
, vol.76
, pp. 8609-8620
-
-
Kakimi, K.1
Isogawa, M.2
Chung, J.3
Sette, A.4
Chisari, F.V.5
-
21
-
-
0026742308
-
Stability of the recombinant hepatitis B core antigen
-
Nath N, Hickman K, Nowlan S, Shah D, Phillips J, Babler S. 1992. Stability of the recombinant hepatitis B core antigen. J Clin Microbiol 30:1617-1619.
-
(1992)
J Clin Microbiol
, vol.30
, pp. 1617-1619
-
-
Nath, N.1
Hickman, K.2
Nowlan, S.3
Shah, D.4
Phillips, J.5
Babler, S.6
-
22
-
-
0032519919
-
The secreted hepatitis B precore antigen can modulate the immune response to the nucleocapsid: a mechanism for persistence
-
Milich DR, Chen MK, Hughes JL, Jones JE. 1998. The secreted hepatitis B precore antigen can modulate the immune response to the nucleocapsid: a mechanism for persistence. J Immunol 160:2013-2021.
-
(1998)
J Immunol
, vol.160
, pp. 2013-2021
-
-
Milich, D.R.1
Chen, M.K.2
Hughes, J.L.3
Jones, J.E.4
-
23
-
-
0004182325
-
Hepatitis B virus gene function: the precore region targets the core antigen to cellular membranes and causes the secretion of the e antigen
-
Ou JH, Laub O, Rutter WJ. 1986. Hepatitis B virus gene function: the precore region targets the core antigen to cellular membranes and causes the secretion of the e antigen. Proc Natl Acad Sci U S A 83:1578-1582. http://dx.doi.org/10.1073/pnas.83.6.1578.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 1578-1582
-
-
Ou, J.H.1
Laub, O.2
Rutter, W.J.3
-
24
-
-
0025741653
-
Immunology and the liver
-
Peters M, Vierling J, Gershwin ME, Milich D, Chisari FV, Hoofnagle JH. 1991. Immunology and the liver. Hepatology 13:977-994. http://dx.doi.org/10.1002/hep.1840130529.
-
(1991)
Hepatology
, vol.13
, pp. 977-994
-
-
Peters, M.1
Vierling, J.2
Gershwin, M.E.3
Milich, D.4
Chisari, F.V.5
Hoofnagle, J.H.6
-
25
-
-
33846502163
-
Hepatitis B virus morphogenesis
-
Bruss V. 2007. Hepatitis B virus morphogenesis. World J Gastroenterol 13:65-73. http://dx.doi.org/10.3748/wjg.v13.i1.65.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 65-73
-
-
Bruss, V.1
-
26
-
-
0030021968
-
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes
-
Guidotti LG, Ishikawa T, Hobbs MV, Matzke B, Schreiber R, Chisari FV. 1996. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 4:25-36. http://dx.doi.org/10.1016/S1074-7613(00)80295-2.
-
(1996)
Immunity
, vol.4
, pp. 25-36
-
-
Guidotti, L.G.1
Ishikawa, T.2
Hobbs, M.V.3
Matzke, B.4
Schreiber, R.5
Chisari, F.V.6
-
27
-
-
0037213545
-
CD8( ) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection
-
Thimme R, Wieland S, Steiger C, Ghrayeb J, Reimann KA, Purcell RH, Chisari FV. 2003. CD8( ) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. J Virol 77:68-76. http://dx.doi.org/10.1128/JVI.77.1.68-76.2003.
-
(2003)
J Virol
, vol.77
, pp. 68-76
-
-
Thimme, R.1
Wieland, S.2
Steiger, C.3
Ghrayeb, J.4
Reimann, K.A.5
Purcell, R.H.6
Chisari, F.V.7
-
28
-
-
0036550559
-
Effector and memory T-cell differentiation: implications for vaccine development
-
Kaech SM, Wherry EJ, Ahmed R. 2002. Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol 2:251-262. http://dx.doi.org/10.1038/nri778.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 251-262
-
-
Kaech, S.M.1
Wherry, E.J.2
Ahmed, R.3
-
29
-
-
80053592167
-
Strategies and implications for prime-boost vaccination to generate memory CD8 T cells
-
Nolz JC, Harty JT. 2011. Strategies and implications for prime-boost vaccination to generate memory CD8 T cells. Adv Exp Med Biol 780:69-83. http://dx.doi.org/10.1007/978-1-4419-5632-3_7.
-
(2011)
Adv Exp Med Biol
, vol.780
, pp. 69-83
-
-
Nolz, J.C.1
Harty, J.T.2
-
30
-
-
0027453541
-
Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis
-
Ando K, Moriyama T, Guidotti LG, Wirth S, Schreiber RD, Schlicht HJ, Huang SN, Chisari FV. 1993. Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med 178:1541-1554.
-
(1993)
J Exp Med
, vol.178
, pp. 1541-1554
-
-
Ando, K.1
Moriyama, T.2
Guidotti, L.G.3
Wirth, S.4
Schreiber, R.D.5
Schlicht, H.J.6
Huang, S.N.7
Chisari, F.V.8
-
31
-
-
0141539335
-
Different immunogenicity of H-2 Kb-restricted epitopes in natural variants of the hepatitis B surface antigen
-
Schirmbeck R, Bohm W, Fissolo N, Melber K, Reimann J. 2003. Different immunogenicity of H-2 Kb-restricted epitopes in natural variants of the hepatitis B surface antigen. Eur J Immunol 33:2429-2438. http://dx.doi.org/10.1002/eji.200324125.
-
(2003)
Eur J Immunol
, vol.33
, pp. 2429-2438
-
-
Schirmbeck, R.1
Bohm, W.2
Fissolo, N.3
Melber, K.4
Reimann, J.5
-
32
-
-
0035863924
-
Overcoming T cell tolerance to the hepatitis B virus surface antigen in hepatitis B virus-transgenic mice
-
Sette AD, Oseroff C, Sidney J, Alexander J, Chesnut RW, Kakimi K, Guidotti LG, Chisari FV. 2001. Overcoming T cell tolerance to the hepatitis B virus surface antigen in hepatitis B virus-transgenic mice. J Immunol 166:1389-1397. http://dx.doi.org/10.4049/jimmunol.166.2.1389.
-
(2001)
J Immunol
, vol.166
, pp. 1389-1397
-
-
Sette, A.D.1
Oseroff, C.2
Sidney, J.3
Alexander, J.4
Chesnut, R.W.5
Kakimi, K.6
Guidotti, L.G.7
Chisari, F.V.8
-
33
-
-
0346121477
-
Breaking tolerance in hepatitis B surface antigen (HBsAg) transgenic mice by vaccination with crossreactive, natural HBsAg variants
-
Schirmbeck R, Dikopoulos N, Kwissa M, Leithauser F, Lamberth K, Buus S, Melber K, Reimann J. 2003. Breaking tolerance in hepatitis B surface antigen (HBsAg) transgenic mice by vaccination with crossreactive, natural HBsAg variants. Eur J Immunol 33:3342-3352. http://dx.doi.org/10.1002/eji.200324403.
-
(2003)
Eur J Immunol
, vol.33
, pp. 3342-3352
-
-
Schirmbeck, R.1
Dikopoulos, N.2
Kwissa, M.3
Leithauser, F.4
Lamberth, K.5
Buus, S.6
Melber, K.7
Reimann, J.8
-
34
-
-
0030751906
-
DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb-and Kd-restricted epitopes
-
Kuhröber A, Wild J, Pudollek HP, Chisari FV, Reimann J. 1997. DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb-and Kd-restricted epitopes. Int Immunol 9:1203-1212. http://dx.doi.org/10.1093/intimm/9.8.1203.
-
(1997)
Int Immunol
, vol.9
, pp. 1203-1212
-
-
Kuhröber, A.1
Wild, J.2
Pudollek, H.P.3
Chisari, F.V.4
Reimann, J.5
-
35
-
-
0029913027
-
DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice
-
Kuhöber A, Pudollek HP, Reifenberg K, Chisari FV, Schlicht HJ, Reimann J, Schirmbeck R. 1996. DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice. J Immunol 156:3687-3695.
-
(1996)
J Immunol
, vol.156
, pp. 3687-3695
-
-
Kuhöber, A.1
Pudollek, H.P.2
Reifenberg, K.3
Chisari, F.V.4
Schlicht, H.J.5
Reimann, J.6
Schirmbeck, R.7
-
36
-
-
17444397463
-
H-2 Kd-restricted hepatitis B virus-derived epitope whose specific CD8+ T lymphocytes can produce gamma interferon without cytotoxicity
-
Chen A, Wang L, Zhang J, Zou L, Jia Z, Zhou W, Wan Y, Wu Y. 2005. H-2 Kd-restricted hepatitis B virus-derived epitope whose specific CD8+ T lymphocytes can produce gamma interferon without cytotoxicity. J Virol 79:5568-5576. http://dx.doi.org/10.1128/JVI.79.9.5568-5576.2005.
-
(2005)
J Virol
, vol.79
, pp. 5568-5576
-
-
Chen, A.1
Wang, L.2
Zhang, J.3
Zou, L.4
Jia, Z.5
Zhou, W.6
Wan, Y.7
Wu, Y.8
|