Histone deacetylase inhibition via RGFP966 releases the brakes on sensory cortical plasticity and the specificity of memory formation

Journal of Neuroscience

Volumn 35, Issue 38, 2015, Pages 13124-13132

  Bieszczad, Kasia M ^a,b,c   Bechay, Kiro ^a   Rusche, James R ^d   Jacques, Vincent ^d   Kudugunti, Shashi ^d   Miao, Wenyan ^d   Weinberger, Norman M ^a   McGaugh, James L ^a   Wood, Marcelo A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Institute for Advanced Study Berlin   (Germany)

^c RUTGERS UNIVERSITY   (United States)

^d REPLIGEN CORPORATION   (United States)

Author keywords

Auditory cortex; Chromatin modification; Cortical plasticity; Epigenetics; Histone acetylation; Memory

Indexed keywords

HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; RGFP966; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; PHENYLENEDIAMINE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY CORTEX; AUDITORY MEMORY; BEHAVIOR ASSESSMENT; CONTROLLED STUDY; DEACETYLATION; DRUG DISTRIBUTION; ELECTROPHYSIOLOGY; ENZYME INHIBITION; EPIGENETICS; HISTONE ACETYLATION; IMMUNOFLUORESCENCE TEST; LEARNING; LIQUID CHROMATOGRAPHY; LONG TERM MEMORY; MALE; MASS SPECTROMETRY; MEMORY TEST; NERVE CELL PLASTICITY; NONHUMAN; PRIMARY AUDITORY CORTEX; PRIORITY JOURNAL; RAT; REWARD; TASK PERFORMANCE; ANIMAL; DRUG EFFECTS; EVOKED RESPONSE; INSTRUMENTAL CONDITIONING; MEMORY; METABOLISM; NONPARAMETRIC TEST; PHYSIOLOGY; REACTION TIME; SPRAGUE DAWLEY RAT; TIME FACTOR; WATER DEPRIVATION;

ACRYLAMIDES; ANIMALS; AUDITORY CORTEX; CONDITIONING, OPERANT; EVOKED POTENTIALS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; MALE; MEMORY; NEURONAL PLASTICITY; PHENYLENEDIAMINES; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; STATISTICS, NONPARAMETRIC; TIME FACTORS; WATER DEPRIVATION;

EID: 84942133647     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/jneurosci.0914-15.2015     Document Type: Article

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