Human papillomaviruses: Shared and distinct pathways for pathogenesis

Current Opinion in Virology

Volumn 14, Issue , 2015, Pages 87-92

  Galloway, Denise A ^a   Laimins, Laimonis A ^b  

^a USA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN E6; PROTEIN E7;

ARTICLE; GENE EXPRESSION; HUMAN; LIFE CYCLE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; RISK FACTOR; VERRUCA VULGARIS; VIRUS CARCINOGENESIS; VIRUS PATHOGENESIS; WART VIRUS; CARCINOGENESIS; COMPARATIVE STUDY; EPITHELIUM CELL; HOST PATHOGEN INTERACTION; PAPILLOMAVIRIDAE; PHYSIOLOGY; VIROLOGY;

CARCINOGENESIS; EPITHELIAL CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; PAPILLOMAVIRIDAE;

EID: 84942103363     PISSN: 18796257     EISSN: 18796265     Source Type: Journal    
DOI: 10.1016/j.coviro.2015.09.001     Document Type: Review

References (56)

1. H.U. Bernard, R.D. Burk, Z. Chen, K. van Doorslaer, H. zur Hausen, and E.M. de Villiers Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments Virology 401 2010 70 79
2. H. zur Hausen Papillomaviruses in the causation of human cancers - a brief historical account Virology 384 2009 260 265
3. L.A. Koutsky, D.A. Galloway, and K.K. Holmes Epidemiology of genital human papillomavirus infection Epidemiol Rev 10 1988 122 163
4. G.Y. Ho, R. Bierman, L. Beardsley, C.J. Chang, and R.D. Burk Natural history of cervicovaginal papillomavirus infection in young women N Engl J Med 338 1998 423 428
5. G.Y. Ho, R.D. Burk, S. Klein, A.S. Kadish, C.J. Chang, P. Palan, J. Basu, R. Tachezy, R. Lewis, and S. Romney Persistent genital human papillomavirus infection as a risk factor for persistent cervical dysplasia J Natl Cancer Inst 87 1995 1365 1371
6. R. Herrero, A. Hildesheim, C. Bratti, M.E. Sherman, M. Hutchinson, J. Morales, I. Balmaceda, M.D. Greenberg, M. Alfaro, R.D. Burk, and et al. Population-based study of human papillomavirus infection and cervical neoplasia in rural Costa Rica J Natl Cancer Inst 92 2000 464 474
7. E. Schwarz, M. Durst, C. Demankowski, O. Lattermann, R. Zech, E. Wolfsperger, S. Suhai, and H. zur Hausen DNA sequence and genome organization of genital human papillomavirus type 6b EMBO J 2 1983 2341 2348
8. B.A. Van Tine, J.C. Kappes, N.S. Banerjee, J. Knops, L. Lai, R.D. Steenbergen, C.L. Meijer, P.J. Snijders, P. Chatis, T.R. Broker, and et al. Clonal selection for transcriptionally active viral oncogenes during progression to cancer J Virol 78 2004 11172 11186
9. P.M. Howley, and H.J. Pfister Beta genus papillomaviruses and skin cancer Virology 479-480 2015 290 296
10. K.M. Michael, T. Waterboer, H. Pfister, M. Gariglio, S. Majewski, M. Favre, and M. Pawlita Seroreactivity of 38 human papillomavirus types in epidermodysplasia verruciformis patients, relatives, and controls J Invest Dermatol 130 2010 841 848
11. M.A. Lutzner, G. Orth, V. Dutronquay, M.F. Ducasse, H. Kreis, and J. Crosnier Detection of human papillomavirus type 5 DNA in skin cancers of an immunosuppressed renal allograft recipient Lancet 2 1983 422 424
12. S. Jackson, C. Harwood, M. Thomas, L. Banks, and A. Storey Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins Genes Dev 14 2000 3065 3073
13. N.A. Wallace, K. Robinson, H.L. Howie, and D.A. Galloway HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage PLoS Pathog 8 2012 e1002807
14. G.P. Marcuzzi, M. Hufbauer, H.U. Kasper, S.J. Weissenborn, S. Smola, and H. Pfister Spontaneous tumour development in human papillomavirus type 8 E6 transgenic mice and rapid induction by UV-light exposure and wounding J Gen Virol 90 2009 2855 2864
15. D. Viarisio, K. Mueller-Decker, U. Kloz, B. Aengeneyndt, A. Kopp-Schneider, H.J. Grone, T. Gheit, C. Flechtenmacher, L. Gissmann, and M. Tommasino E6 and E7 from beta HPV38 cooperate with ultraviolet light in the development of actinic keratosis-like lesions and squamous cell carcinoma in mice PLoS Pathog 7 2011 e1002125
16. C.A. Moody, and L.A. Laimins Human papillomavirus oncoproteins: pathways to transformation Nat Rev Cancer 10 2011 550 560
17. C.A. Moody, and L.A. Laimins Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation PLoS Pathog 5 2009 e1000605
18. K.A. Gillespie, K.P. Mehta, L.A. Laimins, and C.A. Moody Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers J Virol 86 2013 9520 9526
19. K. Mehta, V. Gunasekharan, A. Satsuka, and L.A. Laimins Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators PLoS Pathog 11 2015 e1004763
20. D.C. Anacker, D. Gautam, K.A. Gillespie, W.H. Chappell, and C.A. Moody Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1 J Virol 88 2014 8528 8544
21. G.A. Sowd, D. Mody, J. Eggold, D. Cortez, K.L. Friedman, and E. Fanning SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products PLoS Pathog 10 2014 e1004536
22. N.A. Wallace, K. Robinson, H.L. Howie, and D.A. Galloway beta-HPV 5 and 8 E6 disrupt homology dependent double strand break repair by attenuating BRCA1 and BRCA2 expression and foci formation PLoS Pathog 11 2015 e1004687
23. K. Munger, and D.L. Jones Human papillomavirus carcinogenesis: an identity crisis in the retinoblastoma tumor suppressor pathway J Virol 89 2015 4708 4711
24. A.M. Helt, and D.A. Galloway Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes J Virol 75 2001 6737 6747
25. K. Huh, X. Zhou, H. Hayakawa, J.Y. Cho, T.A. Libermann, J. Jin, J.W. Harper, and K. Munger Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor J Virol 81 2007 9737 9747
26. B. Zhang, W. Chen, and A. Roman The E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradation Proc Natl Acad Sci U S A 103 2006 437 442
27. F.K.D. Fehrman, and L. Laimins The E5 protein of HPV 31 acts to augment cell proliferation and activation of differentiation-dependent late viral functions J Virol 2003
28. S.S. Genther, S. Duensing, K. Munger, C. Sattler, P. Lambert, and P. Lambert Quantitative role of HPV 16 E5 gene during the productive stage of viral life cycle J Virol 77 2003 2832 2842
29. S. Hong, and L.A. Laimins Regulation of the life cycle of HPVs by differentiation and the DNA damage response Future Microbiol 8 2013 1547 1557
30. A.A. McBride The papillomavirus E2 proteins Virology 445 2013 57 79
31. S. Schwartz Papillomavirus transcripts and posttranscriptional regulation Virology 445 2013 187 196
32. X. Cai, G. Li, L.A. Laimins, and B.R. Cullen Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication J Virol 80 2006 10890 10893
33. V. Gunasekharan, and L.A. Laimins Human papillomaviruses modulate microRNA 145 expression to directly control genome amplification J Virol 87 2013 6037 6043
34. E.A. Mesri, M.A. Feitelson, and K. Munger Human viral oncogenesis: a cancer hallmarks analysis Cell Host Microbe 15 2014 266 282
35. R.A. Katzenellenbogen, P. Vliet-Gregg, M. Xu, and D.A. Galloway NFX1-123 increases hTERT expression and telomerase activity posttranscriptionally in human papillomavirus type 16 E6 keratinocytes J Virol 83 2009 6446 6456
36. K. Ganti, J. Broniarczyk, W. Manoubi, P. Massimi, S. Mittal, D. Pim, A. Szalmas, J. Thatte, M. Thomas, V. Tomaic, and et al. The human papillomavirus E6 PDZ binding motif: from life cycle to malignancy Viruses 7 2015 3530 3551
37. E.A. White, R.E. Kramer, M.J. Tan, S.D. Hayes, J.W. Harper, and P.M. Howley Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity J Virol 86 2012 13174 13186
38. C.M. Hebner, and L.A. Laimins Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity Rev Med Virol 16 2006 83 97
39. C.C. McKinney, K.L. Hussmann, and A.A. McBride The role of the DNA damage response throughout the papillomavirus life cycle Viruses 7 2015 2450 2469
40. M.S. Longworth, and L.A. Laimins The binding of histone deacetylases and the integrity of zinc finger-like motifs of the E7 protein are essential for the life cycle of human papillomavirus type 31 J Virol 78 2004 3533 3541
41. J.P. Maufort, A. Shai, H.C. Pitot, and P.F. Lambert A role for HPV16 E5 in cervical carcinogenesis Cancer Res 70 2010 2924 2931
42. M.P. Underbrink, H.L. Howie, K.M. Bedard, J.I. Koop, and D.A. Galloway E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation J Virol 82 2008 10408 10417
43. H.L. Howie, J.I. Koop, J. Weese, K. Robinson, G. Wipf, L. Kim, and D.A. Galloway Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association PLoS Pathog 7 2011 e1002211
44. D. Patel, S.M. Huang, L.A. Baglia, and D.J. McCance The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300 EMBO J 18 1999 5061 5072
45. J.M. Huibregtse, M. Scheffner, and P.M. Howley Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53 Mol Cell Biol 13 1993 775 784
46. N. Brimer, C. Lyons, A.E. Wallberg, and S.B. Vande Pol Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling Oncogene 31 2012 4639 4646
47. I.L. Boxman, L.H. Mulder, F. Noya, V. de Waard, S. Gibbs, T.R. Broker, F. ten Kate, L.T. Chow, and J. ter Schegget Transduction of the E6 and E7 genes of epidermodysplasia-verruciformis-associated human papillomaviruses alters human keratinocyte growth and differentiation in organotypic cultures J Invest Dermatol 117 2001 1397 1404
48. K. Munger, B. Werness, N. Dyson, W. Phelps, E. Harlow, and P. Howley Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product EMBO J 8 1989 4099 4105
49. M.S. Barbosa, W.C. Vass, D.R. Lowy, and J.T. Schiller In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential J Virol 65 1991 292 298
50. S. Caldeira, I. Zehbe, R. Accardi, I. Malanchi, W. Dong, M. Giarre, E.M. de Villiers, R. Filotico, P. Boukamp, and M. Tommasino The E6 and E7 proteins of the cutaneous human papillomavirus type 38 display transforming properties J Virol 77 2003 2195 2206
51. E.A. White, M.E. Sowa, M.J. Tan, S. Jeudy, S.D. Hayes, S. Santha, K. Munger, J.W. Harper, and P.M. Howley Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses Proc Natl Acad Sci U S A 109 2012 E260 E267
52. K.M. Bedard, M.P. Underbrink, H.L. Howie, and D.A. Galloway The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes J Virol 82 2008 3894 3902
53. P. Massimi, P. Zori, S. Roberts, and L. Banks Differential regulation of cell-cell contact, invasion and anoikis by hScrib and hDlg in keratinocytes PLoS ONE 7 2012 e40279
54. I. Cornet, V. Bouvard, M.S. Campo, M. Thomas, L. Banks, L. Gissmann, J. Lamartine, B.S. Sylla, R. Accardi, and M. Tommasino Comparative analysis of transforming properties of E6 and E7 from different beta human papillomavirus types J Virol 86 2012 2366 2370
55. I.D. Schaper, G.P. Marcuzzi, S.J. Weissenborn, H.U. Kasper, V. Dries, N. Smyth, P. Fuchs, and H. Pfister Development of skin tumors in mice transgenic for early genes of human papillomavirus type 8 Cancer Res 65 2005 1394 1400
56. S. Jackson, and A. Storey E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage Oncogene 19 2000 592 598