Disruption of phactr-1 pathway triggers pro-inflammatory and pro-atherogenic factors: New insights in atherosclerosis development

Biochimie

Volumn 118, Issue , 2015, Pages 151-161

  Jarray, Rafika ^a,b   Pavoni, Serena ^b   Borriello, Lucia ^c   Allain, Barbara ^c   Lopez, Nicolas ^d   Bianco, Sara ^c   Liu, Wang Qing ^c   Biard, Denis ^b   Demange, Luc ^c,h   Hermine, Olivier ^e,f,g   Garbay, Christiane ^c   Raynaud, Françoise ^c   Lepelletier, Yves ^e,f,g  

^a The Higher Institute of Biotechnologies of Paris   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d Paris Graduate School of Management (ESG)   (France)

^e INSERM   (France)

^f PARIS DESCARTES SORBONNE PARIS CITÉ UNIVERSITY   (France)

^g CNRS   (France)

^h UNIVERSITÉ DE NICE SOPHIA ANTIPOLIS   (France)

Author keywords

Atherosclerotic factors; MMP regulators; Neuropilin; Phactr 1; VEGF

Indexed keywords

ADAM 9 PROTEIN; ADAM PROTEIN; AMINE OXIDASE (COPPER CONTAINING); CADHERIN; CADHERIN 13; CD36 ANTIGEN; CLUSTERIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE 2; GALECTIN 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIPOPROTEIN RECEPTOR; MATRIX METALLOPROTEINASE; PAXILLIN; PHACTR 1 PROTEIN; PROTEIN; REVERSION INDUCING CYSTEINE RICH PROTEIN WITH KAZAL MOTIF; THROMBIN; THROMBIN RECEPTOR; THROMBIN RECEPTOR 1; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; TROMBOSPONDIN 2; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; VASCULOTROPIN A; ACTIN BINDING PROTEIN; NEUROPILIN; PHACTR-1 PROTEIN, HUMAN; SMALL INTERFERING RNA; VEGFA PROTEIN, HUMAN;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; METABOLIC STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; GENETIC TRANSFECTION; METABOLISM; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

ATHEROSCLEROSIS; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; MICROFILAMENT PROTEINS; NEUROPILINS; POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84942088211     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2015.09.008     Document Type: Article

References (48)

1. P.B. Allen, A.T. Greenfield, P. Svenningsson, D.C. Haspeslagh, and P. Greengard Phactrs 1-4: a family of protein phosphatase 1 and actin regulatory proteins Proc. Natl. Acad. Sci. U. S. A. 101 2004 7187 7192
2. C.J. O'Donnell, M. Kavousi, A.V. Smith, and et al. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction Circulation 124 2011 2855 2864
3. R.S. Patel, A.A. Morris, Y. Ahmed, and et al. A genetic risk variant for myocardial infarction on chromosome 6p24 is associated with impaired central hemodynamic indexes Am. J. Hypertens. 25 2012 797 803
4. J. van Setten, I. Isgum, J. Smolonska, and et al. Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction Atherosclerosis 228 2013 400 405
5. Z. Aherrahrou, and H. Schunkert Genetics of atherosclerosis and vascular calcification go hand-in-hand Atherosclerosis 228 2013 325 326
6. H. Schunkert, I.R. Konig, S. Kathiresan, and et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease Nat. Genet. 43 2011 333 338
7. S. Bevan, M. Traylor, P. Adib-Samii, and et al. Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations Stroke 43 2012 3161 3167
8. L. Qi, L. Parast, T. Cai, and et al. Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies J. Am. Coll. Cardiol. 58 2011 2675 2682
9. S. Kathiresan, B.F. Voight, S. Purcell, and et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants Nat. Genet. 41 2009 334 341
10. B. Allain, R. Jarray, L. Borriello, and et al. Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells Cell Signal 24 2012 214 223
11. S. Koch Neuropilin signalling in angiogenesis Biochem. Soc. Trans. 40 2012 20 25
12. C.A. Staton, I. Kumar, M.W. Reed, and N.J. Brown Neuropilins in physiological and pathological angiogenesis J. Pathol. 212 2007 237 248
13. A. Kawakami, T. Kitsukawa, S. Takagi, and H. Fujisawa Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system J. Neurobiol. 29 1996 1 17
14. A. Eichmann, T. Makinen, and K. Alitalo Neural guidance molecules regulate vascular remodeling and vessel navigation Genes Dev. 19 2005 1013 1021
15. A. Lanahan, X. Zhang, A. Fantin, and et al. The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis Dev. Cell 25 2013 156 168
16. T. Kawasaki, T. Kitsukawa, Y. Bekku, and et al. A requirement for neuropilin-1 in embryonic vessel formation Development 126 1999 4895 4902
17. T. Kitsukawa, A. Shimono, A. Kawakami, H. Kondoh, and H. Fujisawa Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs Development 121 1995 4309 4318
18. F. Li, H. Zhao, Y. Liao, and et al. Higher mortality in heterozygous neuropilin-1 mice after cardiac pressure overload Biochem. Biophys. Res. Commun. 370 2008 317 321
19. D.M. Baston-Buest, A.C. Porn, A. Schanz, and et al. Expression of the vascular endothelial growth factor receptor neuropilin-1 at the human embryo-maternal interface Eur. J. Obstet. Gynecol. Reprod. Biol. 154 2011 151 156
20. C. Pellet-Many, P. Frankel, I.M. Evans, and et al. Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas Biochem. J. 435 2011 609 618
21. J.R. Wild, C.A. Staton, K. Chapple, and B.M. Corfe Neuropilins: expression and roles in the epithelium Int. J. Exp. Pathol. 93 2012 81 103
22. A. Kumanogoh, and H. Kikutani Immunological functions of the neuropilins and plexins as receptors for semaphorins Nat. Rev. Immunol. 13 2013 802 814
23. Z. Vadasz, D. Attias, A. Kessel, and E. Toubi Neuropilins and semaphorins - from angiogenesis to autoimmunity Autoimmun. Rev. 9 2010 825 829
24. S. Soker, S. Takashima, H.Q. Miao, G. Neufeld, and M. Klagsbrun Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor Cell 92 1998 735 745
25. S. Koch, and L. Claesson-Welsh Signal transduction by vascular endothelial growth factor receptors Cold Spring Harb. Perspect. Med. 2 2012 a006502
26. F.S. Grunewald, A.E. Prota, A. Giese, and K. Ballmer-Hofer Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling Biochim. Biophys. Acta 1804 2010 567 580
27. F. Bahram, and L. Claesson-Welsh VEGF-mediated signal transduction in lymphatic endothelial cells Pathophysiology 17 2010 253 261
28. R.G. Keck, L. Berleau, R. Harris, and B.A. Keyt Disulfide structure of the heparin binding domain in vascular endothelial growth factor: characterization of posttranslational modifications in VEGF Arch. Biochem. Biophys. 344 1997 103 113
29. W.J. Fairbrother, M.A. Champe, H.W. Christinger, B.A. Keyt, and M.A. Starovasnik Solution structure of the heparin-binding domain of vascular endothelial growth factor Structure 6 1998 637 648
30. S.J. Harper, and D.O. Bates VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat. Rev. Cancer 8 2008 880 887
31. W.B. Saunders, B.L. Bohnsack, J.B. Faske, and et al. Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3 J. Cell Biol. 175 2006 179 191
32. T. Akahane, M. Akahane, A. Shah, C.M. Connor, and U.P. Thorgeirsson TIMP-1 inhibits microvascular endothelial cell migration by MMP-dependent and MMP-independent mechanisms Exp. Cell Res. 301 2004 158 167
33. S.K. Mitra, D.A. Hanson, and D.D. Schlaepfer Focal adhesion kinase: in command and control of cell motility Nat. Rev. Mol. Cell Biol. 6 2005 56 68
34. J. Oh, T. Diaz, B. Wei, and et al. TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118 Oncogene 25 2006 4230 4234
35. J. Oh, D.W. Seo, T. Diaz, and et al. Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK Cancer Res. 64 2004 9062 9069
36. N. Meng, Y. Li, H. Zhang, and X.F. Sun RECK, a novel matrix metalloproteinase regulator Histol. Histopathol. 23 2008 1003 1010
37. The myocardial infarction-associated gene PHACTR1 is controlled by MEF2 [abstract 2106w] ASHG Meeting 2013
38. H.C. Champion Targeting protein phosphatase 1 in heart failure Circ. Res. 96 2005 708 710
39. L.K. MacDougall, L.R. Jones, and P. Cohen Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban Eur. J. Biochem. 196 1991 725 734
40. J. Heijman, M. Dewenter, A. El-Armouche, and D. Dobrev Function and regulation of serine/threonine phosphatases in the healthy and diseased heart J. Mol. Cell Cardiol. 64 2013 90 98
41. L. Wen, Z. Chen, F. Zhang, and et al. Ca2+/calmodulin-dependent protein kinase kinase beta phosphorylation of Sirtuin 1 in endothelium is atheroprotective Proc. Natl. Acad. Sci. U. S. A. 110 2013 E2420 E2427
42. J. Kalz, H. ten Cate, and H.M. Spronk Thrombin generation and atherosclerosis J. Thromb. Thrombolysis 37 2014 45 55
43. M. Papaspyridonos, E. McNeill, J.P. de Bono, and et al. Galectin-3 is an amplifier of inflammation in atherosclerotic plaque progression through macrophage activation and monocyte chemoattraction Arterioscler. Thromb. Vasc. Biol. 28 2008 433 440
44. J. Golledge, P. Clancy, G.J. Hankey, and P.E. Norman Relation between serum thrombospondin-2 and cardiovascular mortality in older men screened for abdominal aortic aneurysm Am. J. Cardiol. 111 2013 1800 1804
45. N. Oksala, M. Levula, N. Airla, and et al. ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries-Tampere vascular study Ann. Med. 41 2009 279 290
46. E.R. O'Brien, K.L. Bennett, M.R. Garvin, and et al. Beta ig-h3, a transforming growth factor-beta-inducible gene, is overexpressed in atherosclerotic and restenotic human vascular lesions Arterioscler. Thromb. Vasc. Biol. 16 1996 576 584
47. P. Matyus, B. Dajka-Halasz, A. Foldi, and et al. Semicarbazide-sensitive amine oxidase: current status and perspectives Curr. Med. Chem. 11 2004 1285 1298
48. The semicarbazide-sensitive amine oxidase (SSAO): a new actor in atherosclerosis in the APOE mouse model? [abstract p4.10] Artery 6 2011 162