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Volumn 60, Issue 10, 2015, Pages 3044-3052

MicroRNA-145 and MicroRNA-133a Inhibited Proliferation, Migration, and Invasion, While Promoted Apoptosis in Hepatocellular Carcinoma Cells Via Targeting FSCN1

Author keywords

FSCN1; Hepatocellular carcinoma; MicroRNA 133a; MicroRNA 145

Indexed keywords

FASCIN; FASCIN1; MICRORNA; MICRORNA 133A; MICRORNA 145; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CARRIER PROTEIN; FSCN1 PROTEIN, HUMAN; MIRN133 MICRORNA, HUMAN; MIRN145 MICRORNA, HUMAN;

EID: 84942080095     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-015-3706-9     Document Type: Article
Times cited : (36)

References (29)
  • 1
    • 84865510127 scopus 로고    scopus 로고
    • Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation
    • COI: 1:CAS:528:DC%2BC38Xht1KjtbzM
    • Chiba T, Marusawa H, Ushijima T. Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation. Gastroenterology. 2012;143:550–563.
    • (2012) Gastroenterology , vol.143 , pp. 550-563
    • Chiba, T.1    Marusawa, H.2    Ushijima, T.3
  • 2
    • 84901837328 scopus 로고    scopus 로고
    • Virus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC2cXhs1Glu7s%3D
    • Shlomai A, de Jong YP, Rice CM. Virus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma. Semin Cancer Biol. 2014;26:78–88.
    • (2014) Semin Cancer Biol , vol.26 , pp. 78-88
    • Shlomai, A.1    de Jong, Y.P.2    Rice, C.M.3
  • 3
    • 84872572939 scopus 로고    scopus 로고
    • Cancer stem cell as a potential therapeutic target in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC38XhslaqsrnE
    • Pang RW, Poon RT. Cancer stem cell as a potential therapeutic target in hepatocellular carcinoma. Curr Cancer Drug Targets. 2012;12:1081–1094.
    • (2012) Curr Cancer Drug Targets , vol.12 , pp. 1081-1094
    • Pang, R.W.1    Poon, R.T.2
  • 4
    • 84861619812 scopus 로고    scopus 로고
    • MicroRNAs in liver disease
    • COI: 1:CAS:528:DC%2BC38XnslSnsrc%3D
    • Wang XW, Heegaard NH, Orum H. MicroRNAs in liver disease. Gastroenterology. 2012;142:1431–1443.
    • (2012) Gastroenterology , vol.142 , pp. 1431-1443
    • Wang, X.W.1    Heegaard, N.H.2    Orum, H.3
  • 5
    • 84861195622 scopus 로고    scopus 로고
    • Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC38Xnt12mt70%3D
    • Borel F, Konstantinova P, Jansen PL. Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma. J Hepatol. 2012;56:1371–1383.
    • (2012) J Hepatol , vol.56 , pp. 1371-1383
    • Borel, F.1    Konstantinova, P.2    Jansen, P.L.3
  • 6
    • 84867863624 scopus 로고    scopus 로고
    • MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells
    • COI: 1:CAS:528:DC%2BC38XhsFWhs7nJ
    • Wang Z, Zhang X, Yang Z, et al. MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells. Biochem Biophys Res Commun. 2012;427:444–449.
    • (2012) Biochem Biophys Res Commun , vol.427 , pp. 444-449
    • Wang, Z.1    Zhang, X.2    Yang, Z.3
  • 7
    • 84874444612 scopus 로고    scopus 로고
    • miRNA-145 targets v-ets erythroblastosis virus E26 oncogene homolog 1 to suppress the invasion, metastasis, and angiogenesis of gastric cancer cells
    • COI: 1:CAS:528:DC%2BC3sXislOntbw%3D
    • Zheng L, Pu J, Qi T, et al. miRNA-145 targets v-ets erythroblastosis virus E26 oncogene homolog 1 to suppress the invasion, metastasis, and angiogenesis of gastric cancer cells. Mol Cancer Res. 2013;11:182–193.
    • (2013) Mol Cancer Res , vol.11 , pp. 182-193
    • Zheng, L.1    Pu, J.2    Qi, T.3
  • 8
    • 84878249332 scopus 로고    scopus 로고
    • MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer
    • COI: 1:CAS:528:DC%2BC3sXksFOku78%3D
    • Noh JH, Chang YG, Kim MG, et al. MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer. Cancer Lett. 2013;335:455–462.
    • (2013) Cancer Lett , vol.335 , pp. 455-462
    • Noh, J.H.1    Chang, Y.G.2    Kim, M.G.3
  • 9
    • 84902356223 scopus 로고    scopus 로고
    • Establishment of robust controls for the normalization of miRNA expression in neuroendocrine tumors of the ileum and pancreas
    • COI: 1:CAS:528:DC%2BC2cXis1agu70%3D
    • Sperveslage J, Hoffmeister M, Henopp T, et al. Establishment of robust controls for the normalization of miRNA expression in neuroendocrine tumors of the ileum and pancreas. Endocrine. 2014;46:226–230.
    • (2014) Endocrine , vol.46 , pp. 226-230
    • Sperveslage, J.1    Hoffmeister, M.2    Henopp, T.3
  • 10
    • 44949142045 scopus 로고    scopus 로고
    • Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling
    • COI: 1:CAS:528:DC%2BD1cXnsF2jsLk%3D
    • Wong TS, Liu XB, Chung-Wai HA, et al. Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling. Int J Cancer. 2008;123:251–257.
    • (2008) Int J Cancer , vol.123 , pp. 251-257
    • Wong, T.S.1    Liu, X.B.2    Chung-Wai, H.A.3
  • 11
    • 48549091046 scopus 로고    scopus 로고
    • Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis
    • COI: 1:CAS:528:DC%2BD1cXnvFOqtLg%3D
    • Datta J, Kutay H, Nasser MW, et al. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res. 2008;68:5049–5058.
    • (2008) Cancer Res , vol.68 , pp. 5049-5058
    • Datta, J.1    Kutay, H.2    Nasser, M.W.3
  • 12
    • 57749089758 scopus 로고    scopus 로고
    • Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1
    • COI: 1:CAS:528:DC%2BD1cXhsVSgt7zF
    • Nasser MW, Datta J, Nuovo G, et al. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J Biol Chem. 2008;283:33394–33405.
    • (2008) J Biol Chem , vol.283 , pp. 33394-33405
    • Nasser, M.W.1    Datta, J.2    Nuovo, G.3
  • 13
    • 21844439742 scopus 로고    scopus 로고
    • Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker?
    • COI: 1:CAS:528:DC%2BD2MXmt1WhsLk%3D
    • Hashimoto Y, Skacel M, Adams JC. Roles of fascin in human carcinoma motility and signaling: prospects for a novel biomarker? Int J Biochem Cell Biol. 2005;37:1787–1804.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 1787-1804
    • Hashimoto, Y.1    Skacel, M.2    Adams, J.C.3
  • 14
    • 77049108859 scopus 로고    scopus 로고
    • The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion
    • COI: 1:CAS:528:DC%2BC3cXitlWrtL4%3D
    • Li A, Dawson JC, Forero-Vargas M, et al. The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr Biol. 2010;20:339–345.
    • (2010) Curr Biol , vol.20 , pp. 339-345
    • Li, A.1    Dawson, J.C.2    Forero-Vargas, M.3
  • 15
    • 77951875068 scopus 로고    scopus 로고
    • Fascin expression predicts survival after potentially curative resection of node-positive colon cancer
    • Chan C, Jankova L, Fung CL, et al. Fascin expression predicts survival after potentially curative resection of node-positive colon cancer. Am J Surg Pathol. 2010;34:656–666.
    • (2010) Am J Surg Pathol , vol.34 , pp. 656-666
    • Chan, C.1    Jankova, L.2    Fung, C.L.3
  • 16
    • 68949111887 scopus 로고    scopus 로고
    • TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways
    • COI: 1:CAS:528:DC%2BD1MXpvF2hs70%3D
    • Fu H, Hu Z, Wen J, et al. TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways. Acta Biochim Biophys Sin. 2009;41:648–656.
    • (2009) Acta Biochim Biophys Sin , vol.41 , pp. 648-656
    • Fu, H.1    Hu, Z.2    Wen, J.3
  • 17
    • 33748535444 scopus 로고    scopus 로고
    • Role of fascin in filopodial protrusion
    • COI: 1:CAS:528:DC%2BD28XpvVGhurg%3D
    • Vignjevic D, Kojima S, Aratyn Y, et al. Role of fascin in filopodial protrusion. J Cell Biol. 2006;174:863–875.
    • (2006) J Cell Biol , vol.174 , pp. 863-875
    • Vignjevic, D.1    Kojima, S.2    Aratyn, Y.3
  • 18
    • 77049108859 scopus 로고    scopus 로고
    • The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion
    • COI: 1:CAS:528:DC%2BC3cXitlWrtL4%3D
    • Li A, Dawson JC, Forero-Vargas M, et al. The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr Biol. 2010;20:339–345.
    • (2010) Curr Biol , vol.20 , pp. 339-345
    • Li, A.1    Dawson, J.C.2    Forero-Vargas, M.3
  • 19
    • 79956208360 scopus 로고    scopus 로고
    • Fascin: invasive filopodia promoting metastasis
    • Machesky LM, Li A. Fascin: invasive filopodia promoting metastasis. Commun Integr Biol. 2010;3:263–270.
    • (2010) Commun Integr Biol , vol.3 , pp. 263-270
    • Machesky, L.M.1    Li, A.2
  • 20
    • 68949199565 scopus 로고    scopus 로고
    • Fascin expression in serous tumors of ovary correlates with aggressiveness of malignancy
    • Wen YH, Yee H, Goswami S, et al. Fascin expression in serous tumors of ovary correlates with aggressiveness of malignancy. Int J Gynecol Pathol. 2009;28:187–192.
    • (2009) Int J Gynecol Pathol , vol.28 , pp. 187-192
    • Wen, Y.H.1    Yee, H.2    Goswami, S.3
  • 21
    • 71549135533 scopus 로고    scopus 로고
    • Fascin expression in progression and prognosis of hepatocellular carcinoma
    • Iguchi T, Aishima S, Umeda K, et al. Fascin expression in progression and prognosis of hepatocellular carcinoma. J Surg Oncol. 2009;100:575–579.
    • (2009) J Surg Oncol , vol.100 , pp. 575-579
    • Iguchi, T.1    Aishima, S.2    Umeda, K.3
  • 22
    • 79956194652 scopus 로고    scopus 로고
    • Fascin-1 expression correlates with repression of E-cadherin expression in hepatocellular carcinoma cells and augments their invasiveness in combination with matrix metalloproteinases
    • COI: 1:CAS:528:DC%2BC3MXnvVGqtrg%3D
    • Hayashi Y, Osanai M, Lee GH. Fascin-1 expression correlates with repression of E-cadherin expression in hepatocellular carcinoma cells and augments their invasiveness in combination with matrix metalloproteinases. Cancer Sci. 2011;102:1228–1235.
    • (2011) Cancer Sci , vol.102 , pp. 1228-1235
    • Hayashi, Y.1    Osanai, M.2    Lee, G.H.3
  • 23
    • 84862908024 scopus 로고    scopus 로고
    • MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis
    • COI: 1:CAS:528:DC%2BC38XosFCqtA%3D%3D
    • Xu Q, Liu LZ, Qian X, et al. MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. Nucleic Acids Res. 2012;40:761–774.
    • (2012) Nucleic Acids Res , vol.40 , pp. 761-774
    • Xu, Q.1    Liu, L.Z.2    Qian, X.3
  • 24
    • 74249123376 scopus 로고    scopus 로고
    • miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells
    • COI: 1:CAS:528:DC%2BC3cXjt12hsw%3D%3D
    • Spizzo R, Nicoloso MS, Lupini L, et al. miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells. Cell Death Differ. 2010;17:246–254.
    • (2010) Cell Death Differ , vol.17 , pp. 246-254
    • Spizzo, R.1    Nicoloso, M.S.2    Lupini, L.3
  • 25
    • 84899490560 scopus 로고    scopus 로고
    • MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling
    • COI: 1:CAS:528:DC%2BC2cXmtVaht7Y%3D
    • Wang Y, Hu C, Cheng J, et al. MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling. Biochem Biophys Res Commun. 2014;446:1255–1260.
    • (2014) Biochem Biophys Res Commun , vol.446 , pp. 1255-1260
    • Wang, Y.1    Hu, C.2    Cheng, J.3
  • 26
    • 84891875021 scopus 로고    scopus 로고
    • MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer
    • COI: 1:CAS:528:DC%2BC3sXhslGntb7L
    • Akanuma N, Hoshino I, Akutsu Y, et al. MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer. Br J Cancer. 2014;110:189–198.
    • (2014) Br J Cancer , vol.110 , pp. 189-198
    • Akanuma, N.1    Hoshino, I.2    Akutsu, Y.3
  • 27
    • 84862801756 scopus 로고    scopus 로고
    • Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion
    • COI: 1:CAS:528:DC%2BC38XksFGksb8%3D
    • Wu ZS, Wang CQ, Xiang R, et al. Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion. BMC Cancer. 2012;12:51.
    • (2012) BMC Cancer , vol.12 , pp. 51
    • Wu, Z.S.1    Wang, C.Q.2    Xiang, R.3
  • 28
    • 77649271930 scopus 로고    scopus 로고
    • miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer
    • COI: 1:CAS:528:DC%2BC3cXis1ygsrw%3D
    • Chiyomaru T, Enokida H, Tatarano S, et al. miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer. 2010;102:883–891.
    • (2010) Br J Cancer , vol.102 , pp. 883-891
    • Chiyomaru, T.1    Enokida, H.2    Tatarano, S.3
  • 29
    • 77956181723 scopus 로고    scopus 로고
    • miR-145, miR-133a and miR-133b: tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma
    • COI: 1:CAS:528:DC%2BC3cXhtlWhs7fI
    • Kano M, Seki N, Kikkawa N, et al. miR-145, miR-133a and miR-133b: tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. Int J Cancer. 2010;127:2804–2814.
    • (2010) Int J Cancer , vol.127 , pp. 2804-2814
    • Kano, M.1    Seki, N.2    Kikkawa, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.