Comparison of locus-specific databases for BRCA1 and BRCA2 variants reveals disparity in variant classification within and among databases

Journal of Community Genetics

Volumn 6, Issue 4, 2015, Pages 351-359

  Vail, Paris J ^a   Morris, Brian ^a   van Kan, Aric ^a   Burdett, Brianna C ^a   Moyes, Kelsey ^a   Theisen, Aaron ^a   Kerr, Iain D ^a   Wenstrup, Richard J ^a   Eggington, Julie M ^a  

^a Myriad Genetic Laboratories   (United States)

Author keywords

BRCA1; BRCA2; Locus specific variant databases; Variant classification; Variants of uncertain significance

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ACCESS TO INFORMATION; ARTICLE; CLINICAL PRACTICE; CONTROLLED STUDY; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; PRACTICE GUIDELINE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TUMOR SUPPRESSOR GENE; UNITED STATES;

EID: 84941996137     PISSN: 1868310X     EISSN: 18686001     Source Type: Journal    
DOI: 10.1007/s12687-015-0220-x     Document Type: Article

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