Concomitant proton-pump inhibitor use, platelet activity, and clinical outcomes in patients with acute coronary syndromes treated with prasugrel versus clopidogrel and managed without revascularization: Insights from the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes trial

American Heart Journal

Volumn 170, Issue 4, 2015, Pages 683-694.e3

  Nicolau, Jose Carlos ^a   Bhatt, Deepak L ^b   Roe, Matthew T ^c,d   Lokhnygina, Yuliya ^d   Neely, Benjamin ^d   Corbalán, Ramón ^e   Leiva Pons, José L ^f   Martinez, Felipe ^g   Goodman, Shaun G ^h   Winters, Kenneth J ⁱ   Verheugt, Freek W A ^j   Armstrong, Paul W ^k   White, Harvey D ^l   Fox, Keith A A ^m   Prabhakaran, Dorairaj ⁿ   Ohman, E Magnus ^c,d  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^e PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^f Hospital Central Dr Morones Prieto   (Mexico)

^g UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^h ST MICHAEL'S HOSPITAL   (Canada)

ⁱ ELI LILLY AND COMPANY   (United States)

^j ONZE LIEVE VROUWE GASTHUIS   (Netherlands)

^k UNIVERSITY OF ALBERTA   (Canada)

^l AUCKLAND CITY HOSPITAL   (New Zealand)

^m UNIVERSITY OF EDINBURGH   (United Kingdom)

ⁿ PUBLIC HEALTH FOUNDATION OF INDIA   (India)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; OMEPRAZOLE; PANTOPRAZOLE; PRASUGREL; PROTON PUMP INHIBITOR; ANTITHROMBOCYTIC AGENT; PURINERGIC P2Y RECEPTOR ANTAGONIST; TICLOPIDINE;

ACUTE CORONARY SYNDROME; ADULT; AGED; ANGIOGRAPHY; ARTICLE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; COHORT ANALYSIS; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DEPENDENT VARIABLE; DOUBLE BLIND PROCEDURE; DRUG POTENTIATION; DRUG USE; FEMALE; FOLLOW UP; GASTROINTESTINAL HEMORRHAGE; HEART INFARCTION; HUMAN; INCIDENCE; LOADING DRUG DOSE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MORBIDITY; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; OUTCOME ASSESSMENT; PATIENT HISTORY OF CORONARY ARTERY BYPASS GRAFT; PEPTIC ULCER; PLATELET REACTIVITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; ANALOGS AND DERIVATIVES; BLOOD; CLINICAL TRIAL; DOSE RESPONSE; DRUG COMBINATION; DRUG EFFECTS; MIDDLE AGED; MULTICENTER STUDY; PERCUTANEOUS CORONARY INTERVENTION; PRACTICE GUIDELINE; THROMBOCYTE ACTIVATION; TIME;

ACUTE CORONARY SYNDROME; AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; PRACTICE GUIDELINES AS TOPIC; PRASUGREL HYDROCHLORIDE; PROTON PUMP INHIBITORS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; TICLOPIDINE; TIME FACTORS; TREATMENT OUTCOME;

EID: 84941939517     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2015.05.017     Document Type: Article

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