-
1
-
-
84941887593
-
-
Instituto Nacional do Câncer José Alencar Gomes da Silva [homepage on the Internet]. Rio de Janeiro: INCA [cited 2014 Nov 26]. Estimativa 2014 - Incidência de Câncer no Brasil 2014. [Adobe Acrobat document, 126p.]. Available from
-
Ministério da Saúde. Instituto Nacional do Câncer José Alencar Gomes da Silva [homepage on the Internet]. Rio de Janeiro: INCA [cited 2014 Nov 26]. Estimativa 2014 - Incidência de Câncer no Brasil 2014. [Adobe Acrobat document, 126p.]. Available from: http://www.inca.gov.br/estimativa/2014/estimativa-24012014.pdf
-
-
-
-
2
-
-
84941907110
-
-
GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [monograph on the Internet]. Lyon, France: International Agency for Research on Cancer; 2013 [cited 2015 Mar 23]. Available from
-
Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [monograph on the Internet]. Lyon, France: International Agency for Research on Cancer; 2013 [cited 2015 Mar 23]. Available from: http://globocan.iarc.fr
-
-
-
Ferlay, J.1
Soerjomataram, I.2
Ervik, M.3
Dikshit, R.4
Eser, S.5
Mathers, C.6
-
3
-
-
84889670814
-
Mortality distribution due to tracheal, lung, and bronchial cancer by gender, Brazil, 1980-2010
-
Guimarães RM, Santos TS. Mortality distribution due to tracheal, lung, and bronchial cancer by gender, Brazil, 1980-2010. J Bras Pneumol. 2013;39(5):633-5. http://dx.doi.org/10.1590/S1806-37132013000500016
-
(2013)
J Bras Pneumol
, vol.39
, Issue.5
, pp. 633-635
-
-
Guimarães, R.M.1
Santos, T.S.2
-
4
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 2002;346(2):92-8. http://dx.doi.org/10.1056/NEJMoa011954
-
(2002)
N Engl J Med
, vol.346
, Issue.2
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
Langer, C.4
Sandler, A.5
Krook, J.6
-
5
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304(5676):1497-500. http://dx.doi.org/10.1126/science.1099314
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
6
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350(21):2129-39. http://dx.doi.org/10.1056/NEJMoa040938
-
(2004)
N Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
7
-
-
0013825447
-
The stimulation of epidermal proliferation by a specific protein (EGF)
-
Cohen S. The stimulation of epidermal proliferation by a specific protein (EGF). Dev Biol. 1965;12(3):394-407. http://dx.doi.org/10.1016/0012-1606(65)90005-9
-
(1965)
Dev Biol
, vol.12
, Issue.3
, pp. 394-407
-
-
Cohen, S.1
-
8
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene. 2000;19(56):6550-65. http://dx.doi.org/10.1038/sj.onc.1204082
-
(2000)
Oncogene
, vol.19
, Issue.56
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
9
-
-
0031028273
-
Two EGF molecules contribute additively to stabilization of the EGFR dimer
-
Lemmon MA, Bu Z, Ladbury JE, Zhou M, Pinchasi D, Lax I, et al. Two EGF molecules contribute additively to stabilization of the EGFR dimer. EMBO J. 1997;16(2):281-94. http://dx.doi.org/10.1093/emboj/16.2.281
-
(1997)
EMBO J
, vol.16
, Issue.2
, pp. 281-294
-
-
Lemmon, M.A.1
Bu, Z.2
Ladbury, J.E.3
Zhou, M.4
Pinchasi, D.5
Lax, I.6
-
10
-
-
0021204118
-
Autophosphorylation sites on the epidermal growth factor receptor
-
Downward J, Parker P, Waterfield MD. Autophosphorylation sites on the epidermal growth factor receptor. Nature. 1984;311(5985):483-5. http://dx.doi.org/10.1038/311483a0
-
(1984)
Nature
, vol.311
, Issue.5985
, pp. 483-485
-
-
Downward, J.1
Parker, P.2
Waterfield, M.D.3
-
11
-
-
0028888604
-
The PTB domain: A new protein module implicated in signal transduction
-
van der Geer P, Pawson T. The PTB domain: a new protein module implicated in signal transduction. Trends Biochem Sci. 1995;20(7):277-80. http://dx.doi.org/10.1016/S0968-0004(00)89043-X
-
(1995)
Trends Biochem Sci
, vol.20
, Issue.7
, pp. 277-280
-
-
Van Der Geer, P.1
Pawson, T.2
-
12
-
-
0029011218
-
The MAPK signaling cascade
-
Seger R, Krebs EG. The MAPK signaling cascade. FASEB J. 1995;9(9):726-35.
-
(1995)
FASEB J
, vol.9
, Issue.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
13
-
-
0027153103
-
Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor
-
Buday L, Downward J. Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell. 1993;73(3):611-20. http://dx.doi.org/10.1016/0092-8674(93)90146-H
-
(1993)
Cell
, vol.73
, Issue.3
, pp. 611-620
-
-
Buday, L.1
Downward, J.2
-
14
-
-
1642617693
-
PI3K/Akt signalling pathway and cancer
-
Fresno Vara JA, Casado E, de Castro J, Cejas P, Belda- Iniesta C, González-Barón M. PI3K/Akt signalling pathway and cancer. Cancer Treat Rev. 2004;30(2):193-204. http://dx.doi.org/10.1016/j.ctrv.2003.07.007
-
(2004)
Cancer Treat Rev
, vol.30
, Issue.2
, pp. 193-204
-
-
Fresno Vara, J.A.1
Casado, E.2
De Castro, J.3
Cejas, P.4
Belda-Iniesta, C.5
González-Barón, M.6
-
15
-
-
0021281324
-
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
-
Downward J, Yarden Y, Mayes E, Scrace G, Totty N, Stockwell P, et al. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature. 1984;307(5951):521-7. http://dx.doi.org/10.1038/307521a0
-
(1984)
Nature
, vol.307
, Issue.5951
, pp. 521-527
-
-
Downward, J.1
Yarden, Y.2
Mayes, E.3
Scrace, G.4
Totty, N.5
Stockwell, P.6
-
16
-
-
0035256698
-
Untangling the ErbB signalling network
-
Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol. 2001;2(2):127-37. http://dx.doi.org/10.1038/35052073
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, Issue.2
, pp. 127-137
-
-
Yarden, Y.1
Sliwkowski, M.X.2
-
17
-
-
12144287534
-
United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets
-
Cohen MH, Williams GA, Sridhara R, Chen G, McGuinn WD Jr, Morse D, et al. United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets. Clin Cancer Res. 2004;10(4):1212-8. http://dx.doi.org/10.1158/1078-0432.CCR-03-0564
-
(2004)
Clin Cancer Res
, vol.10
, Issue.4
, pp. 1212-1218
-
-
Cohen, M.H.1
Williams, G.A.2
Sridhara, R.3
Chen, G.4
McGuinn, W.D.5
Morse, D.6
-
18
-
-
24644458654
-
FDA drug approval summary: Erlotinib (Tarceva) tablets
-
Cohen MH, Johnson JR, Chen YF, Sridhara R, Pazdur R. FDA drug approval summary: erlotinib (Tarceva) tablets. Oncologist. 2005;10(7):461-6. http://dx.doi.org/10.1634/theoncologist.10-7-461
-
(2005)
Oncologist
, vol.10
, Issue.7
, pp. 461-466
-
-
Cohen, M.H.1
Johnson, J.R.2
Chen, Y.F.3
Sridhara, R.4
Pazdur, R.5
-
19
-
-
84884640384
-
Afatinib: First global approval
-
Dungo RT, Keating GM. Afatinib: first global approval. Drugs. 2013;73(13):1503-15. http://dx.doi.org/10.1007/s40265-013-0111-6
-
(2013)
Drugs
, vol.73
, Issue.13
, pp. 1503-1515
-
-
Dungo, R.T.1
Keating, G.M.2
-
20
-
-
0036817040
-
Epithelial growth factor receptor interacting agents
-
Baselga J, Albanell J. Epithelial growth factor receptor interacting agents. Hematol Oncol Clin North Am. 2002;16(5):1041-63. http://dx.doi.org/10.1016/S0889-8588(02)00055-2
-
(2002)
Hematol Oncol Clin North Am
, vol.16
, Issue.5
, pp. 1041-1063
-
-
Baselga, J.1
Albanell, J.2
-
21
-
-
0036795061
-
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa)
-
Bianco C, Tortora G, Bianco R, Caputo R, Veneziani BM, Caputo R, et al. Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa). Clin Cancer Res. 2002;8(10):3250-8.
-
(2002)
Clin Cancer Res
, vol.8
, Issue.10
, pp. 3250-3258
-
-
Bianco, C.1
Tortora, G.2
Bianco, R.3
Caputo, R.4
Veneziani, B.M.5
Caputo, R.6
-
22
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
-
Erratum in: J Clin Oncol. 2004 Dec 1;22(23):4863
-
Fukuoka M, Yano S, Giaccone G, Tamura T, Nakagawa K, Douillard JY, et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol. 2003;21(12):2237-46. Erratum in: J Clin Oncol. 2004 Dec 1;22(23):4863. http://dx.doi.org/10.1200/JCO.2003.10.038
-
(2003)
J Clin Oncol
, vol.21
, Issue.12
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
Tamura, T.4
Nakagawa, K.5
Douillard, J.Y.6
-
23
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
-
Kris MG, Natale RB, Herbst RS, Lynch TJ Jr, Prager D, Belani CP, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA. 2003;290(16):2149-58. http://dx.doi.org/10.1001/jama.290.16.2149
-
(2003)
JAMA
, vol.290
, Issue.16
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch, T.J.4
Prager, D.5
Belani, C.P.6
-
24
-
-
1542503746
-
Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial--INTACT 1
-
Giaccone G, Herbst RS, Manegold C, Scagliotti G, Rosell R, Miller V, et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial--INTACT 1. J Clin Oncol. 2004;22(5):777-84. http://dx.doi.org/10.1200/JCO.2004.08.001
-
(2004)
J Clin Oncol
, vol.22
, Issue.5
, pp. 777-784
-
-
Giaccone, G.1
Herbst, R.S.2
Manegold, C.3
Scagliotti, G.4
Rosell, R.5
Miller, V.6
-
25
-
-
1542713370
-
Gefitinib in combination with paclitaxel and carboplatin in advanced non-smallcell lung cancer: A phase III trial--INTACT 2
-
Herbst RS, Giaccone G, Schiller JH, Natale RB, Miller V, Manegold C, et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-smallcell lung cancer: a phase III trial--INTACT 2. J Clin Oncol. 2004;22(5):785-94. http://dx.doi.org/10.1200/JCO.2004.07.215
-
(2004)
J Clin Oncol
, vol.22
, Issue.5
, pp. 785-794
-
-
Herbst, R.S.1
Giaccone, G.2
Schiller, J.H.3
Natale, R.B.4
Miller, V.5
Manegold, C.6
-
26
-
-
24944440830
-
TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
-
Herbst RS, Prager D, Hermann R, Fehrenbacher L, Johnson BE, Sandler A, et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol. 2005;23(25):5892-9. http://dx.doi.org/10.1200/JCO.2005.02.840
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 5892-5899
-
-
Herbst, R.S.1
Prager, D.2
Hermann, R.3
Fehrenbacher, L.4
Johnson, B.E.5
Sandler, A.6
-
27
-
-
34248140107
-
Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial
-
Gatzemeier U, Pluzanska A, Szczesna A, Kaukel E, Roubec J, De Rosa F, et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: the Tarceva Lung Cancer Investigation Trial. J Clin Oncol. 2007;25(12):1545-52. http://dx.doi.org/10.1200/JCO.2005.05.1474
-
(2007)
J Clin Oncol
, vol.25
, Issue.12
, pp. 1545-1552
-
-
Gatzemeier, U.1
Pluzanska, A.2
Szczesna, A.3
Kaukel, E.4
Roubec, J.5
De Rosa, F.6
-
28
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, Tan EH, Hirsh V, Thongprasert S, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med. 2005;353(2):123-32. http://dx.doi.org/10.1056/NEJMoa050753
-
(2005)
N Engl J Med
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
Tan, E.H.4
Hirsh, V.5
Thongprasert, S.6
-
29
-
-
2642539590
-
Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, “Iressa”) on an expanded access study
-
Jänne PA, Gurubhagavatula S, Yeap BY, Lucca J, Ostler P, Skarin AT, et al. Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, “Iressa”) on an expanded access study. Lung Cancer. 2004;44(2):221-30. http://dx.doi.org/10.1016/j.lungcan.2003.12.014
-
(2004)
Lung Cancer
, vol.44
, Issue.2
, pp. 221-230
-
-
Jänne, P.A.1
Gurubhagavatula, S.2
Yeap, B.Y.3
Lucca, J.4
Ostler, P.5
Skarin, A.T.6
-
30
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
Thatcher N, Chang A, Parikh P, Rodrigues Pereira J, Ciuleanu T, von Pawel J, et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet. 2005;366(9496):1527-37. http://dx.doi.org/10.1016/S0140-6736(05)67625-8
-
(2005)
Lancet
, vol.366
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
Rodrigues Pereira, J.4
Ciuleanu, T.5
Von Pawel, J.6
-
31
-
-
56249109644
-
Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial
-
Kim ES, Hirsh V, Mok T, Socinski MA, Gervais R, Wu YL, et al. Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. Lancet. 2008;372(9652):1809-18. http://dx.doi.org/10.1016/S0140-6736(08)61758-4
-
(2008)
Lancet
, vol.372
, pp. 1809-1818
-
-
Kim, E.S.1
Hirsh, V.2
Mok, T.3
Socinski, M.A.4
Gervais, R.5
Wu, Y.L.6
-
32
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
Hanna N, Shepherd FA, Fossella FV, Pereira JR, De Marinis F, von Pawel J, et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol. 2004;22(9):1589-97. http://dx.doi.org/10.1200/JCO.2004.08.163
-
(2004)
J Clin Oncol
, vol.22
, Issue.9
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
Pereira, J.R.4
De Marinis, F.5
Von Pawel, J.6
-
33
-
-
41049100716
-
Mutations in the epidermal growth factor receptor gene and effects of EGFR-tyrosine kinase inhibitors on lung cancers
-
Fukui T, Mitsudomi T. Mutations in the epidermal growth factor receptor gene and effects of EGFR-tyrosine kinase inhibitors on lung cancers. Gen Thorac Cardiovasc Surg. 2008;56(3):97-103. http://dx.doi.org/10.1007/s11748-007-0193-8
-
(2008)
Gen Thorac Cardiovasc Surg
, vol.56
, Issue.3
, pp. 97-103
-
-
Fukui, T.1
Mitsudomi, T.2
-
34
-
-
28444478439
-
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants
-
Greulich H, Chen TH, Feng W, Jänne PA, Alvarez JV, Zappaterra M, et al. Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants. PLoS Med. 2005;2(11):e313. http://dx.doi.org/10.1371/journal. pmed.0020313
-
(2005)
Plos Med
, vol.2
, Issue.11
-
-
Greulich, H.1
Chen, T.H.2
Feng, W.3
Jänne, P.A.4
Alvarez, J.V.5
Zappaterra, M.6
-
35
-
-
33947224133
-
Differential constitutive activation of the epidermal growth factor receptor in non-small cell lung cancer cells bearing EGFR gene mutation and amplification
-
Okabe T, Okamoto I, Tamura K, Terashima M, Yoshida T, Satoh T, et al. Differential constitutive activation of the epidermal growth factor receptor in non-small cell lung cancer cells bearing EGFR gene mutation and amplification. Cancer Res. 2007;67(5):2046-53. http://dx.doi.org/10.1158/0008-5472.CAN-06-3339
-
(2007)
Cancer Res
, vol.67
, Issue.5
, pp. 2046-2053
-
-
Okabe, T.1
Okamoto, I.2
Tamura, K.3
Terashima, M.4
Yoshida, T.5
Satoh, T.6
-
36
-
-
34250833290
-
Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cells
-
Akca H, Tani M, Hishida T, Matsumoto S, Yokota J. Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cells. Lung Cancer. 2006;54(1):25-33. http://dx.doi.org/10.1016/j.lungcan.2006.06.007
-
(2006)
Lung Cancer
, vol.54
, Issue.1
, pp. 25-33
-
-
Akca, H.1
Tani, M.2
Hishida, T.3
Matsumoto, S.4
Yokota, J.5
-
37
-
-
84902811306
-
EGFR mutation screening in non-small cell lung cancer: Results from an access program in Brazil
-
5s (suppl; abstr 1526)
-
Pontes LDEB, Bacchi CE, Queiroga EM, Piha T, Miranda PA, Freire S, et al. EGFR mutation screening in non-small cell lung cancer: results from an access program in Brazil. J Clin Oncol. 2014;32:5s (suppl; abstr 1526).
-
(2014)
J Clin Oncol
, vol.32
-
-
Pontes, L.1
Bacchi, C.E.2
Queiroga, E.M.3
Piha, T.4
Miranda, P.A.5
Freire, S.6
-
38
-
-
84863980235
-
Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients
-
Bacchi CE, Ciol H, Queiroga EM, Benine LC, Silva LH, Ojopi EB, et al. Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients. Clinics (Sao Paulo). 2012;67(5): 419–24. http://dx.doi.org/10.6061/clinics/2012(05)03
-
(2012)
Clinics (Sao Paulo)
, vol.67
, Issue.5
, pp. 419-424
-
-
Bacchi, C.E.1
Ciol, H.2
Queiroga, E.M.3
Benine, L.C.4
Silva, L.H.5
Ojopi, E.B.6
-
39
-
-
49149118719
-
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
-
Li D, Ambrogio L, Shimamura T, Kubo S, Takahashi M, Chirieac LR, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 2008;27(34):4702-11. http://dx.doi.org/10.1038/onc.2008.109
-
(2008)
Oncogene
, vol.27
, Issue.34
, pp. 4702-4711
-
-
Li, D.1
Ambrogio, L.2
Shimamura, T.3
Kubo, S.4
Takahashi, M.5
Chirieac, L.R.6
-
40
-
-
80052511675
-
Final efficacy results from OAM4558g, a randomized phase II study evaluating MetMAb or placebo in combination with erlotinib in advanced NSCLC
-
(suppl; abstr 7505)
-
Spigel DR, Ervin TJ, Ramlau R, Daniel DB, Goldschmidt JH, Blumenschein GR, et al. Final efficacy results from OAM4558g, a randomized phase II study evaluating MetMAb or placebo in combination with erlotinib in advanced NSCLC. J Clin Oncol. 2011;29 (suppl; abstr 7505).
-
(2011)
J Clin Oncol
, vol.29
-
-
Spigel, D.R.1
Ervin, T.J.2
Ramlau, R.3
Daniel, D.B.4
Goldschmidt, J.H.5
Blumenschein, G.R.6
-
41
-
-
84865506979
-
Rationale and design of MARQUEE: A phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer
-
Scagliotti GV, Novello S, Schiller JH, Hirsh V, Sequist LV, Soria JC, et al. Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer. Clin Lung Cancer. 2012;13(5):391-5. http://dx.doi.org/10.1016/j.cllc.2012.01.003
-
(2012)
Clin Lung Cancer
, vol.13
, Issue.5
, pp. 391-395
-
-
Scagliotti, G.V.1
Novello, S.2
Schiller, J.H.3
Hirsh, V.4
Sequist, L.V.5
Soria, J.C.6
-
42
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, Yang CH, Chu DT, Saijo N et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009;361(10):947-57. http://dx.doi.org/10.1056/NEJMoa0810699
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
Yang, C.H.4
Chu, D.T.5
Saijo, N.6
-
43
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K, Sugawara S, Oizumi S, Isobe H, et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med. 2010;362(25):2380-8. http://dx.doi.org/10.1056/NEJMoa0909530
-
(2010)
N Engl J Med
, vol.362
, Issue.25
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
Sugawara, S.4
Oizumi, S.5
Isobe, H.6
-
44
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
-
Mitsudomi T, Morita S, Yatabe Y, Negoro S, Okamoto I, Tsurutani J, et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol. 2010;11(2):121-8. http://dx.doi.org/10.1016/S1470-2045(09)70364-X
-
(2010)
Lancet Oncol
, vol.11
, Issue.2
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
Negoro, S.4
Okamoto, I.5
Tsurutani, J.6
-
45
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou C, Wu YL, Chen G, Feng J, Liu XQ, Wang C, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol. 2011;12(8):735-42. http://dx.doi.org/10.1016/S1470-2045(11)70184-X
-
(2011)
Lancet Oncol
, vol.12
, Issue.8
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
Feng, J.4
Liu, X.Q.5
Wang, C.6
-
46
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R, Vergnenegre A, Massuti B, Felip E, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol. 2012;13(3):239-46. http://dx.doi.org/10.1016/S1470-2045(11)70393-X
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
Vergnenegre, A.4
Massuti, B.5
Felip, E.6
-
47
-
-
84884736973
-
Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
-
Sequist LV, Yang JC, Yamamoto N, O’Byrne K, Hirsh V, Mok T, et al. Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol. 2013;31(27):3327-34. http://dx.doi.org/10.1200/JCO.2012.44.2806
-
(2013)
J Clin Oncol
, vol.31
, Issue.27
, pp. 3327-3334
-
-
Sequist, L.V.1
Yang, J.C.2
Yamamoto, N.3
O’Byrne, K.4
Hirsh, V.5
Mok, T.6
-
48
-
-
84892997539
-
Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-smallcell lung cancer harbouring EGFR mutations (LUX-Lung 6): An open-label, randomised phase 3 trial
-
Wu YL, Zhou C, Hu CP, Feng J, Lu S, Huang Y, et al. Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-smallcell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial. Lancet Oncol. 2014;15(2):213-22. http://dx.doi.org/10.1016/S1470-2045(13)70604-1
-
(2014)
Lancet Oncol
, vol.15
, Issue.2
, pp. 213-222
-
-
Wu, Y.L.1
Zhou, C.2
Hu, C.P.3
Feng, J.4
Lu, S.5
Huang, Y.6
-
49
-
-
84921892043
-
Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): Analysis of overall survival data from two randomised, phase 3 trials
-
Yang JC, Wu YL, Schuler M, Sebastian M, Popat S, Yamamoto N, et al. Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials. Lancet Oncol. 2015;16(2):141-51. http://dx.doi.org/10.1016/S1470-2045(14)71173-8
-
(2015)
Lancet Oncol
, vol.16
, Issue.2
, pp. 141-151
-
-
Yang, J.C.1
Wu, Y.L.2
Schuler, M.3
Sebastian, M.4
Popat, S.5
Yamamoto, N.6
-
50
-
-
79960702788
-
Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS)
-
Fukuoka M, Wu YL, Thongprasert S, Sunpaweravong P, Leong SS, Sriuranpong V, et al. Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS). J Clin Oncol. 2011;29(21):2866-74. http://dx.doi.org/10.1200/JCO.2010.33.4235
-
(2011)
J Clin Oncol
, vol.29
, Issue.21
, pp. 2866-2874
-
-
Fukuoka, M.1
Wu, Y.L.2
Thongprasert, S.3
Sunpaweravong, P.4
Leong, S.S.5
Sriuranpong, V.6
-
51
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R, Moran T, Queralt C, Porta R, Cardenal F, Camps C, et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med. 2009;361(10):958-67. http://dx.doi.org/10.1056/NEJMoa0904554
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
Porta, R.4
Cardenal, F.5
Camps, C.6
-
52
-
-
84984568870
-
Clinical practice guidelines for the prevention and treatment of EGFR inhibitorassociated dermatologic toxicities
-
Lacouture ME, Anadkat MJ, Bensadoun RJ, Bryce J, Chan A, Epstein JB, et al. Clinical practice guidelines for the prevention and treatment of EGFR inhibitorassociated dermatologic toxicities. Support Care Cancer. 2011;19(8):1079-95. http://dx.doi.org/10.1007/s00520-011-1197-6
-
(2011)
Support Care Cancer
, vol.19
, Issue.8
, pp. 1079-1095
-
-
Lacouture, M.E.1
Anadkat, M.J.2
Bensadoun, R.J.3
Bryce, J.4
Chan, A.5
Epstein, J.B.6
-
53
-
-
84877109191
-
CNS metastases in non-small-cell lung cancer: Current role of EGFR-TKI therapy and future perspectives
-
Berger LA, Riesenberg H, Bokemeyer C, Atanackovic D. CNS metastases in non-small-cell lung cancer: current role of EGFR-TKI therapy and future perspectives. Lung Cancer. 2013;80(3):242-8. http://dx.doi.org/10.1016/j.lungcan.2013.02.004
-
(2013)
Lung Cancer
, vol.80
, Issue.3
, pp. 242-248
-
-
Berger, L.A.1
Riesenberg, H.2
Bokemeyer, C.3
Atanackovic, D.4
-
54
-
-
84937525369
-
ASPIRATION: First-line erlotinib (E) until and beyond RECIST progression (PD) in Asian patients (pts) with EGFR mutation-positive (mut+) NSCLC
-
Park K, Ahn M, Yu C, Kim S, Lin M, Sriuranpong V, et al. ASPIRATION: first-line erlotinib (E) until and beyond RECIST progression (PD) in Asian patients (pts) with EGFR mutation-positive (mut+) NSCLC. Ann Oncol. 2014;25 (suppl 4):iv426-iv427. http://dx.doi.org/10.1093/annonc/mdu349.2
-
(2014)
Ann Oncol
, vol.25
, pp. iv426-iv427
-
-
Park, K.1
Ahn, M.2
Yu, C.3
Kim, S.4
Lin, M.5
Sriuranpong, V.6
-
55
-
-
79952376771
-
Treatment of non–small-cell lung cancer with erlotinib or gefitinib
-
Cataldo VD, Gibbons DL, Pérez-Soler R, Quintás-Cardama A. Treatment of non–small-cell lung cancer with erlotinib or gefitinib. N Engl J Med. 2011;364(10):947-55. http://dx.doi.org/10.1056/NEJMct0807960
-
(2011)
N Engl J Med
, vol.364
, Issue.10
, pp. 947-955
-
-
Cataldo, V.D.1
Gibbons, D.L.2
Pérez-Soler, R.3
Quintás-Cardama, A.4
-
56
-
-
84881230220
-
Biomarkers (BM) France: Results of routine EGFR, HER2, KRAS, BRAF, PI3KCA mutations detection and EML4-ALK gene fusion assessment on the first 10,000 non-small cell lung cancer (NSCLC) patients (pts)
-
(suppl; abstr 8000)
-
Barlesi F, Blons H, Beau-Faller M, Rouquette I, Ouafik L, Mosser J, et al. Biomarkers (BM) France: Results of routine EGFR, HER2, KRAS, BRAF, PI3KCA mutations detection and EML4-ALK gene fusion assessment on the first 10,000 non-small cell lung cancer (NSCLC) patients (pts). J Clin Oncol. 2013;31 (suppl; abstr 8000).
-
(2013)
J Clin Oncol
, vol.31
-
-
Barlesi, F.1
Blons, H.2
Beau-Faller, M.3
Rouquette, I.4
Ouafik, L.5
Mosser, J.6
-
57
-
-
84880917028
-
Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
-
Lindeman NI, Cagle PT, Beasley MB, Chitale DA, Dacic S, Giaccone G, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology. J Thorac Oncol. 2013;8(7):823-59. http://dx.doi.org/10.1097/JTO.0b013e318290868f
-
(2013)
J Thorac Oncol
, vol.8
, Issue.7
, pp. 823-859
-
-
Lindeman, N.I.1
Cagle, P.T.2
Beasley, M.B.3
Chitale, D.A.4
Dacic, S.5
Giaccone, G.6
-
58
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, et al. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med. 2008;359(4):366-77. http://dx.doi.org/10.1056/NEJMoa0800668
-
(2008)
N Engl J Med
, vol.359
, Issue.4
, pp. 366-377
-
-
Maheswaran, S.1
Sequist, L.V.2
Nagrath, S.3
Ulkus, L.4
Brannigan, B.5
Collura, C.V.6
-
59
-
-
0017681196
-
DNA sequencing with chain-terminating inhibitors
-
Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1977;74(12):5463-7. http://dx.doi.org/10.1073/pnas.74.12.5463
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, Issue.12
, pp. 5463-5467
-
-
Sanger, F.1
Nicklen, S.2
Coulson, A.R.3
-
60
-
-
34548849132
-
Epidermal growth factor receptor mutation testing in lung cancer: Searching for the ideal method
-
Pao W, Ladanyi M. Epidermal growth factor receptor mutation testing in lung cancer: searching for the ideal method. Clin Cancer Res. 2007;13(17):4954-5. http://dx.doi.org/10.1158/1078-0432.CCR-07-1387
-
(2007)
Clin Cancer Res
, vol.13
, Issue.17
, pp. 4954-4955
-
-
Pao, W.1
Ladanyi, M.2
-
61
-
-
33746100318
-
Detection of epidermal growth factor receptor mutations in serum as a predictor of the response to gefitinib in patients with non-small-cell lung cancer
-
Kimura H, Kasahara K, Kawaishi M, Kunitoh H, Tamura T, Holloway B, et al. Detection of epidermal growth factor receptor mutations in serum as a predictor of the response to gefitinib in patients with non-small-cell lung cancer. Clin Cancer Res. 2006;12(13):3915-21. http://dx.doi.org/10.1158/1078-0432.CCR-05-2324
-
(2006)
Clin Cancer Res
, vol.12
, Issue.13
, pp. 3915-3921
-
-
Kimura, H.1
Kasahara, K.2
Kawaishi, M.3
Kunitoh, H.4
Tamura, T.5
Holloway, B.6
-
62
-
-
84911866971
-
Molecular testing for selection of patients with lung cancer for Epidermal Growth Factor Receptor and Anaplastic Lymphoma Kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology guideline
-
Leighl NB, Rekhtman N, Biermann WA, Huang J, Mino-Kenudson M, Ramalingam SS, et al. Molecular testing for selection of patients with lung cancer for Epidermal Growth Factor Receptor and Anaplastic Lymphoma Kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology guideline. J Clin Oncol. 2014;32(32):3673-9. http://dx.doi.org/10.1200/JCO.2014.57.3055
-
(2014)
J Clin Oncol
, vol.32
, Issue.32
, pp. 3673-3679
-
-
Leighl, N.B.1
Rekhtman, N.2
Biermann, W.A.3
Huang, J.4
Mino-Kenudson, M.5
Ramalingam, S.S.6
-
63
-
-
77955486952
-
Prediction of epidermal growth factor receptor mutations in the plasma/pleural effusion to efficacy of gefitinib treatment in advanced non-small cell lung cancer
-
Jian G, Songwen Z, Ling Z, Qinfang D, Jie Z, Liang T, et al. Prediction of epidermal growth factor receptor mutations in the plasma/pleural effusion to efficacy of gefitinib treatment in advanced non-small cell lung cancer. J Cancer Res Clin Oncol. 2010;136(9):1341-7. http://dx.doi.org/10.1007/s00432-010-0785-z
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, Issue.9
, pp. 1341-1347
-
-
Jian, G.1
Songwen, Z.2
Ling, Z.3
Qinfang, D.4
Jie, Z.5
Liang, T.6
-
64
-
-
31544459265
-
Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay
-
Asano H, Toyooka S, Tokumo M, Ichimura K, Aoe K, Ito S, et al. Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay. Clin Cancer Res. 2006;12(1):43-8. http://dx.doi.org/10.1158/1078-0432.CCR-05-0934
-
(2006)
Clin Cancer Res
, vol.12
, Issue.1
, pp. 43-48
-
-
Asano, H.1
Toyooka, S.2
Tokumo, M.3
Ichimura, K.4
Aoe, K.5
Ito, S.6
-
65
-
-
23844544647
-
Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinomas
-
Pan Q, Pao W, Ladanyi M. Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinomas. J Mol Diagn. 2005;7(3):396-403. http://dx.doi.org/10.1016/S1525-1578(10)60569-7
-
(2005)
J Mol Diagn
, vol.7
, Issue.3
, pp. 396-403
-
-
Pan, Q.1
Pao, W.2
Ladanyi, M.3
-
66
-
-
33745985181
-
A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer
-
Yatabe Y, Hida T, Horio Y, Kosaka T, Takahashi T, Mitsudomi T. A rapid, sensitive assay to detect EGFR mutation in small biopsy specimens from lung cancer. J Mol Diagn. 2006;8(3):335-41. http://dx.doi.org/10.2353/jmoldx.2006.050104
-
(2006)
J Mol Diagn
, vol.8
, Issue.3
, pp. 335-341
-
-
Yatabe, Y.1
Hida, T.2
Horio, Y.3
Kosaka, T.4
Takahashi, T.5
Mitsudomi, T.6
-
67
-
-
33845989517
-
Detection of epidermal growth factor receptor variations by partially denaturing HPLC
-
Chin TM, Anuar D, Soo R, Salto-Tellez M, Li WQ, Ahmad B, et al. Detection of epidermal growth factor receptor variations by partially denaturing HPLC. Clin Chem. 2007;53(1):62-70. http://dx.doi.org/10.1373/clinchem.2006.074831
-
(2007)
Clin Chem
, vol.53
, Issue.1
, pp. 62-70
-
-
Chin, T.M.1
Anuar, D.2
Soo, R.3
Salto-Tellez, M.4
Li, W.Q.5
Ahmad, B.6
-
68
-
-
78650928556
-
Detection of EGFR mutations with mutation-specific antibodies in stage IV non-smallcell lung cancer
-
Simonetti S, Molina MA, Queralt C, de Aguirre I, Mayo C, Bertran-Alamillo J, et al. Detection of EGFR mutations with mutation-specific antibodies in stage IV non-smallcell lung cancer. J Transl Med. 2010;8:135. http://dx.doi.org/10.1186/1479-5876-8-135
-
(2010)
J Transl Med
, vol.8
, pp. 135
-
-
Simonetti, S.1
Molina, M.A.2
Queralt, C.3
De Aguirre, I.4
Mayo, C.5
Bertran-Alamillo, J.6
-
69
-
-
79551563284
-
International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma
-
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol. 2011;6(2):244-85. http://dx.doi.org/10.1097/JTO.0b013e318206a221
-
(2011)
J Thorac Oncol
, vol.6
, Issue.2
, pp. 244-285
-
-
Travis, W.D.1
Brambilla, E.2
Noguchi, M.3
Nicholson, A.G.4
Geisinger, K.R.5
Yatabe, Y.6
-
70
-
-
84879071011
-
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
-
Shaw AT, Kim DW, Nakagawa K, Seto T, Crinó L, Ahn MJ, et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med. 2013;368(25):2385-94. http://dx.doi.org/10.1056/NEJMoa1214886
-
(2013)
N Engl J Med
, vol.368
, Issue.25
, pp. 2385-2394
-
-
Shaw, A.T.1
Kim, D.W.2
Nakagawa, K.3
Seto, T.4
Crinó, L.5
Ahn, M.J.6
-
71
-
-
36248980204
-
Characterizing the cancer genome in lung adenocarcinoma
-
Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, et al. Characterizing the cancer genome in lung adenocarcinoma. Nature. 2007;450(7171):893-8. http://dx.doi.org/10.1038/nature06358
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 893-898
-
-
Weir, B.A.1
Woo, M.S.2
Getz, G.3
Perner, S.4
Ding, L.5
Beroukhim, R.6
-
72
-
-
84905029258
-
Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma
-
Erratum in: Nature. 2014;514(7521):262
-
Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014;511(7511):543-50. Erratum in: Nature. 2014;514(7521):262. http://dx.doi.org/10.1038/nature13385
-
(2014)
Nature
, vol.511
, Issue.7511
, pp. 543-550
-
-
-
73
-
-
84883055532
-
Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): A randomised controlled trial
-
Garassino MC, Martelli O, Broggini M, Farina G, Veronese S, Rulli E, et al. Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial. Lancet Oncol. 2013;14(10):981-8. http://dx.doi.org/10.1016/S1470-2045(13)70310-3
-
(2013)
Lancet Oncol
, vol.14
, Issue.10
, pp. 981-988
-
-
Garassino, M.C.1
Martelli, O.2
Broggini, M.3
Farina, G.4
Veronese, S.5
Rulli, E.6
-
74
-
-
74949110711
-
Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Jackman D, Pao W, Riely GJ, Engelman JA, Kris MG, Jänne PA, et al. Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. J Clin Oncol. 2010;28(2):357-60. http://dx.doi.org/10.1200/JCO.2009.24.7049
-
(2010)
J Clin Oncol
, vol.28
, Issue.2
, pp. 357-360
-
-
Jackman, D.1
Pao, W.2
Riely, G.J.3
Engelman, J.A.4
Kris, M.G.5
Jänne, P.A.6
-
75
-
-
77953541527
-
Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: A multicentre, randomised, placebo-controlled phase 3 study
-
Cappuzzo F, Ciuleanu T, Stelmakh L, Cicenas S, Szczésna A, Juhász E, et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol. 2010;11(6):521-9. http://dx.doi.org/10.1016/S1470-2045(10)70112-1
-
(2010)
Lancet Oncol
, vol.11
, Issue.6
, pp. 521-529
-
-
Cappuzzo, F.1
Ciuleanu, T.2
Stelmakh, L.3
Cicenas, S.4
Szczésna, A.5
Juhász, E.6
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