A distinct alleles and genetic recombination of pmrCAB operon in species of Acinetobacter baumannii complex isolates

Diagnostic Microbiology and Infectious Disease

Volumn 82, Issue 3, 2015, Pages 183-188

  Kim, Dae Hun ^a   Ko, Kwan Soo ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Acinetobacter nosocomialis; Acinetobacter pittii; Acinetobacter seifertii; pmrCAB

Indexed keywords

COLISTIN; POLYMYXIN B; BACTERIAL DNA; BACTERIAL PROTEIN;

ACINETOBACTER; ACINETOBACTER BAUMANNII; ACINETOBACTER NOSOCOMIALIS; ALLELE; AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; CONTROLLED STUDY; GENETIC RECOMBINATION; GENETIC VARIABILITY; KOREA; MULTILOCUS SEQUENCE TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PHYLOGENETIC TREE; PMRCAB GENE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ACINETOBACTER INFECTION; CHEMISTRY; CLUSTER ANALYSIS; DNA SEQUENCE; GENETIC POLYMORPHISM; GENETICS; HOSPITAL; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; MOLECULAR GENETICS; PHYLOGENY; SEQUENCE HOMOLOGY;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; ALLELES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CLUSTER ANALYSIS; DNA, BACTERIAL; HOSPITALS; HUMANS; KOREA; MOLECULAR SEQUENCE DATA; OPERON; PHYLOGENY; POLYMORPHISM, GENETIC; RECOMBINATION, GENETIC; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84941874905     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2015.03.021     Document Type: Article

References (23)

1. Adams M.D., Nickel G.C., Bajaksouzian S., Lavender H., Murthy A.R., Jacobs M.R., et al. Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system. Antimicrob Agents Chemother 2009, 53:3628-3634.
2. Arroyo L.A., Herrera C.M., Fernandez L., Hankins J.V., Trent M.S., Hancock R.E. The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17978 and clinical isolates through phosphoethanolamine modification of lipid A. Antimicrob Agents Chemother 2011, 55:3743-3751.
3. Bartual S.G., Seifert H., Hippler C., Luzon M.A.D., Wisplinghoff H., Rodriguez-Valera F. Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J Clin Microbiol 2005, 43:4382-4390.
4. Beceiro A., Llobet E., Aranda J., Bengoechea J.A., Doumith M., Horsney M., et al. Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system. Antimicrob Agents Chemother 2011, 55:3370-3379.
5. Cai Y., Chai D., Wang R., Liang B., Bai N. Colistin resistance of Acinetobactor baumannii: clinical reports, mechanisms and antimicrobial strategies. J Antimicrob Chemother 2012, 67:1607-1615.
6. Clinical and Laboratory Standards Institute (CLSI) Performance standards for antimicrobial susceptibility testing; 19th informational supplement. M100-S19 2013, Clinical and Laboratory Standards Institute, Wayne, PA.
7. Dijkshoorn L., Nemec A., Seifert H. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat Rev Microbiol 2007, 5:939-951.
8. Falagas M.E., Kasiakou S.K. Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clin Infect Dis 2005, 40:1333-1341.
9. Fishbain J., Peleg A.Y. Treatment of Acinetobacter infections. Clin Infect Dis 2010, 51:79-84.
10. Kim D.H., Park Y.K., Choi J.Y., Ko K.S. Identification of genetic recombination between Acinetobacter species based on multilocus sequence analysis. Diagn Microbiol Infect Dis 2012, 73:284-286.
11. Ko K.S., Suh J.Y., Kwon K.T., Jung S.I., Park K.H., Kang C.I., et al. High rates of resistance to colistin and polymyxin B in subgroups of Acinetobacter baumannii isolates from Korea. J Antimicrob Chemother 2007, 60:1163-1167.
12. Lesho E., Yoon E.J., McGann P., Snesrud E., Kwak Y., Milillo M., et al. Emergence of colistin-resistance in extremely drug-resistant Acinetobacter baumannii containing a novel pmrCAB operon during colistin therapy of wound infections. J Infect Dis 2013, 208:1142-1151.
13. Li J., Nation R.L., Milne R.W., Turnidge J.D., Coulthard K. Evaluation of colistin as an agent against multi-resistant Gram-negative bacteria. Int J Antimicrob Agents 2005, 25:11-25.
14. Lopez-Rojas R., Jimenez-Mejias M.E., Lepe J.A., Pachon J. Acinetobacter baumannii resistant to colistin alters its antibiotic resistance profile: a case report from Spain. J Infect Dis 2011, 204:1147-1148.
15. Mitrophanov A.Y., Jewett M.W., Hadley T.J., Groisman E.A. Evolution and dynamics of regulatory architectures controlling polymyxin B resistance in enteric bacteria. PLoS Genet 2008, 4:e1000233.
16. Moffatt J.H., Harper M., Harrison P., Hale J.D., Vinogradov E., Seemann T., et al. Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production. Antimicrob Agents Chemother 2010, 54:4971-4977.
17. Moffatt J.H., Harper M., Adler B., Nation R.L., Li J., Boyce J.D. Insertion sequence ISAba1 is involved in colistin resistance and loss of lipolysaccharide in Acinetobacter baumannii. Antimicrob Agents Chemother 2011, 55:3022-3024.
18. Nemec A., Krizova L., Maixnerova M., van der Reijden T.J.K., Deschaght P., Passet V., et al. Genotypic and phenotypic characterization of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex with the proposal of Acinetobacter pittii sp. nov. (formerly Acinetobacter genomic species 3) and Acinetobacter nosocomialis sp. nov. (formerly Acinetobacter genomic species 13TU). Res Microbiol 2011, 162:393-404.
19. Park Y.K., Jung S.I., Park K.H., Cheong D.R., Peck K.R., Song J.H., et al. Independent emergence of colistin-resistant Acinetobacter spp. isolates from Korea. Diagn Microbiol Infect Dis 2009, 64:51-59.
20. Park Y.K., Choi J.Y., Shin D., Ko K.S. Correlation between overexpression and amino acid substitution of the PmrAB locus and colistin resistance in Acinetobacter baumannii. Int J Antimicrob Agents 2011, 37:525-530.
21. Park Y.K., Jung S.I., Park K.H., Kim D.H., Choi J.Y., Kim S.H., et al. Changes in antimicrobial susceptibility and major clones of Acinetobacter calcoaceticus-baumannii complex isolates from a single hospital in Korea over 7 years. J Med Microbiol 2012, 61:71-79.
22. Peleg A., Seifert H., Paterson D.L. Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 2008, 21:538-558.
23. Pournaras S., Poulou A., Dafopoulou K., Chabane Y.N., Kristo I., Makris D., et al. Growth retardation, reduced invasiveness, and impaired colistin-mediated cell death associated with colistin resistance development in Acinetobacter baumannii. Antimicrob Agents Chemother 2014, 58:828-832.