Standardized test for anti-Tr/DNER in patients with paraneoplastic cerebellar degeneration

Neurology: Neuroimmunology and NeuroInflammation

Volumn 2, Issue 2, 2015, Pages e68-

  Probst, Christian ^a   Komorowski, Lars ^a   De Graaff, Esther ^b   Van Coevorden Hameete, Marleen ^b,c   Rogemond, Veronique ^d,e,f   Honnorat, Jerome ^d,e,f   Sabeter, Lidia ^g   Graus, Francesc ^g   Jarius, Sven ^h   Voltz, Raymond ⁱ   Wildemann, Brigitte ^h   Franciotta, Diego ^j   Blocker, Inga M ^a   Schlumberger, Wolfgang ^a   Stocker, Winfried ^a   Smitt, Peter A E Sillevis ^c  

^a Institute of Experimental Immunology   (Germany)

^b UTRECHT UNIVERSITY   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d HÔPITAL NEUROLOGIQUE   (France)

^e LYON NEUROSCIENCE RESEARCH CENTER   (France)

^f UNIVERSITÉ LYON 1   (France)

^g INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^h UNIVERSITY OF HEIDELBERG   (Germany)

ⁱ UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^j C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

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Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CDR2 PROTEIN; CDR2L PROTEIN; CYTOKINE; DELTA NOTCH LIKE EPIDERMAL GROWTH FACTOR RELATED RECEPTOR; DELTA NOTCH LIKE EPIDERMAL GROWTH FACTOR RELATED RECEPTOR ANTIBODY; RECOMBINANT RECEPTOR; TR ANTIBODY; TUMOR MARKER; UNCLASSIFIED DRUG; YO ANTIBODY;

ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; BLOOD DONOR; CEREBELLUM; CLINICAL ARTICLE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; HEK293 CELL LINE; HODGKIN DISEASE; HUMAN; HUMAN CELL; IMMUNOADSORPTION; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; NONHUMAN; PARANEOPLASTIC NEUROPATHY; PRIORITY JOURNAL; RECOMBINANT CELL BASED INDIRECT IMMUNOFLUORESCENCE ASSAY; RHEUMATIC DISEASE; SENSITIVITY AND SPECIFICITY;

EID: 84941757370     PISSN: None     EISSN: 23327812     Source Type: Journal    
DOI: 10.1212/NXI.0000000000000068     Document Type: Article

References (22)

1. Darnell RB, Posner JB. Paraneoplastic Syndromes. New York: Oxford University Press, Inc.; 2011.
2. Graus F, Delattre JY, Antoine JC, et al. Recommended diagnostic criteria for paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry 2004;75:1135-1140.
3. de Beukelaar JW, Sillevis Smitt PA. Managing paraneoplas-tic neurological disorders. Oncologist 2006;11:292-305.
4. Shams'ili S, Grefkens J, de LB, et al. Paraneoplastic cere-bellar degeneration associated with antineuronal antibodies: analysis of 50 patients. Brain 2003;126:1409-1418.
5. Horwich L, Buxton PH, Ryan GM. Cerebellar degeneration with Hodgkin's disease. J Neurol Neurosurg Psychiatry 1966;29:45-51.
6. Trotter JL, Hendin BA, Osterland CK. Cerebellar degeneration with Hodgkin disease. An immunological study. Arch Neurol 1976;33:660-661.
7. Graus F, Dalmau J, Valldeoriola F, et al. Immunological characterization of a neuronal antibody (anti-Tr) associ-ated with paraneoplastic cerebellar degeneration and Hodgkin's disease. J Neuroimmunol 1997;74:55-61.
8. Graus F, Gultekin SH, Ferrer I, Reiriz J, Alberch J, Dalmau J. Localization of the neuronal antigen recognized by anti-Tr antibodies from patients with paraneoplastic cerebellar degeneration and Hodgkin's disease in the rat nervous system. Acta Neuropathol 1998;96:1-7.
9. Bernal F, Shams'ili S, Rojas I, et al. Anti-Tr antibodies as markers of paraneoplastic cerebellar degeneration and Hodgkin's disease. Neurology 2003;60:230-234.
10. de Graaff E, Maat P, Hulsenboom E, et al. Identification of delta/notch-like epidermal growth factor-related recep-tor as the Tr antigen in paraneoplastic cerebellar degeneration. Ann Neurol 2012;71:815-824.
11. Greene M, Lai Y, Baella N, Dalmau J, Lancaster E. Antibodies to Delta/notch-like epidermal growth factor-related receptor in patients with anti-Tr, paraneoplastic cerebellar degeneration, and Hodgkin lymphoma. JAMA Neurol 2014;71:1003-8.
12. Bernal F, Graus F, Pifarre A, Saiz A, Benyahia B, Ribalta T. Immunohistochemical analysis of anti-Hu-associated paraneoplastic encephalomyelitis. Acta Neuropathol 2002;103:509-515.
13. Stöcker W, Otte M, Ulrich S, et al. Autoimmunity to pancreatic juice in Crohn's disease. Results of an autoan-tibody screening in patients with chronic inflammatory bowel disease. Scand J Gastroenterol Suppl 1987;139: 41-52.
14. Schmidt E, Dähnrich C, Rosemann A, et al. Novel ELISA systems for antibodies to desmoglein 1 and 3: correlation of disease activity with serum autoantibody levels in indi vidual pemphigus patients. Exp Dermatol 2010;19: 458-463.
15. Koy C, Mikkat S, Raptakis E, et al. Matrix-assisted laser desorption/ionization-quadrupole ion trap-time of flight mass spectrometry sequencing resolves structures of unidentified peptides obtained by in-gel tryptic digestion of haptoglobin derivatives from human plasma proteomes. Proteomics 2003;3:851-858.
16. Pruss H, Dalmau J, Harms L, et al. Retrospective analysis of NMDA receptor antibodies in encephalitis of unknown origin. Neurology 2010;75:1735-1739.
17. Jarius S, Probst C, Borowski K, et al. Standardized method for the detection of antibodies to aquaporin-4 based on a highly sensitive immunofluorescence assay employing recombinant target antigen. J Neurol Sci 2010;291:52-56.
18. Jarius S, Wildemann B. Aquaporin-4 antibodies (NMO-IgG) as a serological marker of neuromyelitis optica: a critical review of the literature. Brain Pathol 2013;23: 661-683.
19. Jaeckle KA, Graus F, Houghton A, Cardon-Cardo C, Nielsen SL, Posner JB. Autoimmune response of patients with paraneoplastic cerebellar degeneration to a Purkinje cell cytoplasmic protein antigen. Ann Neurol 1985;18: 592-600.
20. Graus F, Cordon-Cardo C, Posner JB. Neuronal antinu-clear antibody in sensory neuronopathy from lung cancer. Neurology 1985;35:538-543.
21. Honnorat J, Antoine JC, Derrington E, Aguera M, Belin MF. Antibodies to a subpopulation of glial cells and a 66 kDa developmental protein in patients with par-aneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry 1996;61:270-278.
22. Hoftberger R, Dalmau J, Graus F. Clinical neuropathol-ogy practice guide 5-2012: updated guideline for the diagnosis of antineuronal antibodies. Clin Neuropathol 2012; 31:337-341.