Small fiber neuropathy in women with fibromyalgia. An in vivo assessment using corneal confocal bio-microscopy

Seminars in Arthritis and Rheumatism

Volumn 45, Issue 2, 2015, Pages 214-219

  Ramírez, Manuel ^a   Martínez Martínez, Laura Aline ^b   Hernández Quintela, Everardo ^a   Velazco Casapía, Jorge ^a   Vargas, Angélica ^b   Martínez Lavín, Manuel ^b  

^a Asociacion para Evitar la Ceguera en Mexico IAP   (Mexico)

^b INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

Author keywords

Corneal confocal microscopy; Dorsal root ganglia; Fibromyalgia; Neuropathic pain; Small fiber neuropathy; Sympathetic pain

Indexed keywords

ADULT; ARTICLE; BIOMICROSCOPY; CENTRAL CORNEAL THICKNESS; CLINICAL ARTICLE; CONFOCAL MICROSCOPE; CONTROLLED STUDY; CORNEA; CORNEAL CONFOCAL BIOMICROSCOPY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; FIBROMYALGIA; HUMAN; IN VIVO STUDY; NEUROPATHIC PAIN; NON INVASIVE PROCEDURE; OPHTHALMOLOGIST; PATHOGENESIS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; QUESTIONNAIRE; SKIN BIOPSY; SMALL FIBER NEUROPATHY; COMPLICATION; CONFOCAL MICROSCOPY; ERYTHROMELALGIA; INNERVATION; MIDDLE AGED; PAIN MEASUREMENT; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

ADULT; CORNEA; ERYTHROMELALGIA; FEMALE; FIBROMYALGIA; HUMANS; MICROSCOPY, CONFOCAL; MIDDLE AGED; PAIN MEASUREMENT; SEVERITY OF ILLNESS INDEX;

EID: 84941739480     PISSN: 00490172     EISSN: 1532866X     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2015.03.003     Document Type: Article

References (32)

1. Wolfe F., Clauw D.J., Fitzcharles M.A., Goldenberg D.L., Katz R.S., Mease P., et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res (Hoboken) 2010, 62:600-610.
2. Martinez-Lavin M. Fibromyalgia: when distress becomes (un)sympathetic pain. Pain Res Treat 2012, 2012:981565.
3. Uceyler N., Zeller D., Kahn A.K., Kewenig S., Kittel-Schneider S., Schmid A., et al. Small fibre pathology in patients with fibromyalgia syndrome. Brain 2013, 136:1857-1867.
4. Oaklander A.L., Herzog Z.D., Downs H.M., Klein M.M. Objective evidence that small-fiber polyneuropathy underlies some illnesses currently labeled as fibromyalgia. Pain 2013, 154:2310-2316.
5. Serra J., Collado A., Sola R., Antonelli F., Torres X., Salgueiro M., et al. Hyperexcitable C nociceptors in fibromyalgia. Ann Neurol 2014, 75:196-208.
6. Giannoccaro M.P., Donadio V., Incensi A., Avoni P., Liguori R. Small nerve fiber involvement in patients referred for fibromyalgia. Muscle Nerve 2014, 49:757-759.
7. Caro X.J., Winter E.F. Evidence of abnormal epidermal nerve fiber density in fibromyalgia: clinical and immunologic implications. Arthritis Rheumatol 2014, 66:1945-1954.
8. Kosmidis M.L., Koutsogeorgopoulou L., Alexopoulos H., Mamali I., Vlachoyiannopoulos P.G., Voulgarelis M., et al. Reduction of Intraepidermal Nerve Fiber Density (IENFD) in the skin biopsies of patients with fibromyalgia: a controlled study. J Neurol Sci 2014, 347:143-147.
9. Tavee J., Zhou L. Small fiber neuropathy: a burning problem. Cleve Clin J Med 2009, 76:297-305.
10. Tavakoli M., Marshall A., Pitceathly R., Fadavi H., Gow D., Roberts M.E., et al. Corneal confocal microscopy: a novel means to detect nerve fibre damage in idiopathic small fibre neuropathy. Exp Neurol 2010, 223:245-250.
11. Cavanagh H.D., Jester J.V., Essepian J., Shields W., Lemp M.A. Confocal microscopy of the living eye. Clao J 1990, 16:65-73.
12. Fishbaugh J. Cornea: confocal microscopy. Insight 1994, 19:26-27.
13. Ramirez M., Hernandez-Quintela E., Naranjo-Tackman R. Epi-LASIK: a confocal microscopy analysis of the corneal epithelium and anterior stroma. Ophthalmic Surg Lasers Imaging 2012, 43:319-322.
14. Ramirez M., Hernandez-Quintela E., Naranjo-Tackman R. Early confocal microscopy findings after cross-linking treatment. Arch Soc Esp Oftalmol 2013, 88:179-183.
15. Ramirez Fernandez M., Hernandez Quintela E., Naranjo Tackman R. Comparison of stromal corneal nerves between normal and keratoconus patients using confocal microscopy. Arch Soc Esp Oftalmol 2014, 89:308-312.
16. Burckhardt C.S., Clark S.R., Bennett R.M. The fibromyalgia impact questionnaire: development and validation. J Rheumatol 1991, 18:728-733.
17. Hays R.D., Stewart A.L. Sleep measures. In Measuring Functioning and Well-Being: The Medical Outcomes Study Approach 1992, 235-259. Duke University Press. A. Stewart, J. Ware, N.C. Durham (Eds.).
18. Suarez G.A., Opfer-Gehrking T.L., Offord K.P., Atkinson E.J., O[U+05F3]Brien P.C., Low P.A. The autonomic symptom profile: a new instrument to assess autonomic symptoms. Neurology 1999, 52:523-528.
19. Zigmond A.S., Snaith R.P. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983, 67:361-370.
20. Piper B., Lindsey A., Dodd M., Ferketich S., Paul S., Weller S. The development of an instrument to measure the subjective dimension of fatigue. In key aspects of comfort. Management of Pain, Fatigue, and Nausea 1989, 199-207. Springer, New York. S. Funk, E. Tornquist, M. Champagne, R. Wiese (Eds.).
21. Ware J.E., Sherbourne C.D. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992, 30:473-483.
22. Bennett M. The LANSS pain scale: the Leeds assessment of neuropathic symptoms and signs. Pain 2001, 92:147-157.
23. Bouhassira D., Attal N. Diagnosis and assessment of neuropathic pain: the saga of clinical tools. Pain 2011, 152:S74-S83.
24. Asghar O., Petropoulos I.N., Alam U., Jones W., Jeziorska M., Marshall A., et al. Corneal confocal microscopy detects neuropathy in subjects with impaired glucose tolerance. Diabetes Care 2014, 37:2643-2646.
25. Persson A.K., Liu S., Faber C.G., Merkies I.S., Black J.A., Waxman S.G. Neuropathy-associated Nav1.7 variant I228M impairs integrity of dorsal root ganglion neuron axons. Ann Neurol 2013, 73:140-145.
26. McLachlan E.M., Janig W., Devor M., Michaelis M. Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature 1993, 363:543-546.
27. Vargas-Alarcon G., Alvarez-Leon E., Fragoso J.M., Vargas A., Martinez A., Vallejo M., et al. A SCN9A gene-encoded dorsal root ganglia sodium channel polymorphism associated with severe fibromyalgia. BMC Musculoskelet Disord 2012, 13:23.
28. Faber C.G., Hoeijmakers J.G., Ahn H.S., Cheng X., Han C., Choi J.S., et al. Gain of function Nanu1.7 mutations in idiopathic small fiber neuropathy. Ann Neurol 2012, 71:26-39.
29. Martinez-Lavin M., Lopez S., Medina M., Nava A. Use of the Leeds assessment of neuropathic symptoms and signs questionnaire in patients with fibromyalgia. Semin Arthritis Rheum 2003, 32:407-411.
30. Lerma C., Martinez A., Ruiz N., Vargas A., Infante O., Martinez-Lavin M. Nocturnal heart rate variability parameters as potential fibromyalgia biomarker: correlation with symptoms severity. Arthritis Res Ther 2011, 13:R185.
31. Martinez-Lavin M., Vidal M., Barbosa R.E., Pineda C., Casanova J.M., Nava A. Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]. BMC Musculoskelet Disord 2002, 3:2.
32. Clauw D.J. Fibromyalgia: a clinical review. J Am Med Assoc 2014, 311:1547-1555.