Two novel prediction models improve predictions of skin corrosive sub-categories by test methods of OECD Test Guideline No. 431

Toxicology in Vitro

Volumn 29, Issue 8, 2015, Pages 2055-2080

  Desprez, Bertrand ^a   Barroso, João ^a   Griesinger, Claudius ^a   Kandárová, Helena ^b   Alépée, Nathalie ^c   Fuchs, Horst W ^d  

^a JOINT RESEARCH CENTRE   (Italy)

^b MatTek In vitro Life Science Laboratories   (Slovakia)

^c L ORÉAL RECHERCHE   (France)

^d Biotechnologie Vertrieb GmbH   (Germany)

Author keywords

OECD; Prediction model; Skin corrosion; Sub categorization; UN GHS

Indexed keywords

10 UNDECENOIC ACID; 2 METHYLBUTYRIC ACID; 2 OXOGLUTARIC ACID; 2 PROPANOL; ACRYLIC ACID; BICARBONATE; BISULFITE; BUTYRIC ACID; CARVACROL; CINNAMALDEHYDE; CYCLOHEXYLAMINE; DODECYL SULFATE SODIUM; ETHANOLAMINE; EUGENOL; FORMIC ACID; HYDROBROMIC ACID; HYDROCHLORIC ACID; LACTIC ACID; LAURIC ACID; MALEIC ANHYDRIDE; OXALIC ACID; PALMITIC ACID METHYL ESTER; PHENOL; PHOSPHORIC ACID; POTASSIUM HYDROXIDE; PROPIONIC ACID; SILVER NITRATE; SODIUM CARBONATE; TETRACHLOROETHYLENE; CAUSTIC AGENT;

ACCURACY; ARTICLE; CELL VIABILITY; EPICS TEST METHOD; EPIDERM TEST METHOD; EPISKIN TEST METHOD; INTERMETHOD COMPARISON; INVESTIGATIVE PROCEDURES; NONBIOLOGICAL MODEL; POST HOC ANALYSIS; PREDICTION; PREDICTION MODEL; PROCESS DESIGN; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SKINETHIC TEST METHOD; ANIMAL TESTING ALTERNATIVE; CHEMICALLY INDUCED; EPIDERMIS; HUMAN; PATHOLOGY; PRACTICE GUIDELINE; PREDICTIVE VALUE; PROCEDURES; REPRODUCIBILITY; SKIN DISEASE; STANDARDS; TOXICITY TESTING;

ANIMAL TESTING ALTERNATIVES; CAUSTICS; EPIDERMIS; GUIDELINES AS TOPIC; HUMANS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SKIN DISEASES; SKIN IRRITANCY TESTS; TOXICITY TESTS;

EID: 84941711151     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.08.015     Document Type: Article

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