Bridges to cross, burn, and mend: Cells of renin lineage as podocyte progenitors

American Journal of Physiology - Renal Physiology

Volumn 309, Issue 6, 2015, Pages F499-F500

  Altintas, Mehmet M ^a   Reiser, Jochen ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RENIN;

BOWMAN CAPSULE; CELL LINEAGE; CELL MIGRATION; CELL REGENERATION; CHRONIC KIDNEY DISEASE; EDITORIAL; ELECTRON MICROSCOPY; EPITHELIUM CELL; FOCAL GLOMERULOSCLEROSIS; GLOMERULAR FILTRATION BARRIER; GLOMERULOPATHY; HUMAN; JUXTAGLOMERULAR APPARATUS; KIDNEY; KIDNEY DISEASE; NEPHRECTOMY; NONHUMAN; PARIETAL EPITHELIAL CELL; PERICYTE; PHENOTYPE; PODOCYTE; PRIORITY JOURNAL; STEM CELL; UNINEPHRECTOMY; AGING; ANIMAL; GENETICS; PATHOLOGY;

AGING; ANIMALS; CELL LINEAGE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; PHENOTYPE; PODOCYTES; RENIN;

EID: 84941652297     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00301.2015     Document Type: Editorial

References (10)

1. Appel D, Kershaw DB, Smeets B, Yuan G, Fuss A, Frye B, Elger M, Kriz W, Floege J, Moeller MJ. Recruitment of podocytes from glomerular parietal epithelial cells. J Am Soc Nephrol 20: 333–343, 2009.
2. Benigni A, Morigi M, Rizzo P, Gagliardini E, Rota C, Abbate M, Ghezzi S, Remuzzi A, Remuzzi G. Inhibiting angiotensin-converting enzyme promotes renal repair by limiting progenitor cell proliferation and restoring the glomerular architecture. Am J Pathol 179: 628–638, 2011.
3. Hackl MJ, Burford JL, Villanueva K, Lam L, Suszták K, Schermer B, Benzing T, Peti-Peterdi J. Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nat Med 19: 1661–1666, 2013.
4. Mundel P, Shankland SJ. Podocyte biology and response to injury. J Am Soc Nephrol 13: 3005–3015, 2002.
5. Pavenstädt H, Kriz W, Kretzler M. Cell biology of the glomerular podocyte. Physiol Rev 83: 253–307, 2003.
6. Pippin JW, Glenn ST, Krofft RD, Rusiniak ME, Alpers CE, Hudkins K, Duffield JS, Gross KW, Shankland SJ. Cells of renin lineage take on a podocyte phenotype in aging nephropathy. Am J Physiol Renal Physiol 306: F1198–F1209, 2014.
7. Pippin JW, Kaverina NV, Eng DG, Krofft RD, Glenn ST, Duffield JS, Gross KW, Shankland SJ. Cells of renin lineage are adult pluripotent progenitors in experimental glomerular disease. Am J Physiol Renal Physiol 309: F341–F358, 2015.
8. Pippin JW, Sparks MA, Glenn ST, Buitrago S, Coffman TM, Duffield JS, Gross KW, Shankland SJ: Cells of renin lineage are progenitors of podocytes, and parietal epithelial cells in experimental glomerular disease. Am J Pathol 183: 542–557, 2013.
9. Ronconi E, Sagrinati C, Angelotti ML, Lazzeri E, Mazzinghi B, Ballerini L, Parente E, Becherucci F, Gacci M, Carini M, Maggi E, Serio M, Vannelli GB, Lasagni L, Romagnani S, Romagnani P. Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol 20: 322–332, 2009.
10. Shankland SJ, Smeets B, Pippin JW, Moeller MJ. The emergence of the glomerular parietal epithelial cell. Nat Rev Nephrol 10: 158–173, 2014.