Determination of Saponins and Flavonoids in Ivy leaf extracts using HPLC-DAD

Journal of Chromatographic Science

Volumn 53, Issue 4, 2015, Pages 478-483

  Yu, Miao ^a   Shin, Young June ^b   Kim, Nanyoung ^c   Yoo, Guijae ^c   Park, SeonJu ^c   Kim, Seung Hyun ^c  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Central RandD Center Ahn Gook Pharm Co Ltd   (South Korea)

^c Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVONOID; PLANT EXTRACT; SAPONIN;

CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IVY; PLANT LEAF; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVONOIDS; HEDERA; LINEAR MODELS; PLANT EXTRACTS; PLANT LEAVES; REPRODUCIBILITY OF RESULTS; SAPONINS; SENSITIVITY AND SPECIFICITY;

EID: 84941644600     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/bmu068     Document Type: Article

References (19)

1. Stauss-Grabo, M., Atiye, S., Warnke, A., Wedemeyer, R.S., Donath, F., Blume, H.H.; Observational study on the tolerability and safety of filmcoated tablets containing ivy extract (Prospanw Cough Tablets) in the treatment of colds accompanied by coughing; Phytomedicine, (2011); 18: 433-436
2. Cwientzek, U., Ottillinger, B., Arenberger, P.; Acute bronchitis therapy with ivy leaves extracts in a two-Arm study A double-blind, randomised study vs. another ivy leaves extract; Phytomedicine, (2011); 18: 1105-1109
3. European Medicines Agency, Committee on Herbal Medicinal Products; Assessment report on Hedera helix L., folium; European Medicines Agency, London, (2011)
4. Fazio, S., Pouso, J., Dolinsky, D., Fernandez, A., Hernandez, M., Clavier, G., et al.; Tolerance, safety and efficacy of Hedera helix extract in inflammatory bronchial diseases under clinical practice conditions: a prospective, open, multicentre postmarketing study in 9657 patients; Phytomedicine, (2009); 16: 17-24
5. Holzinger, F., Chenot, J.-F.; Systematic review of clinical trials assessing the effectiveness of ivy leaf (Hedera helix) for acute upper respiratory tract infections; Evidence-Based Complementary and Alternative Medicine, (2010); 2011: 1-9
6. Bedir, E., Kirmizipekmez, H., Sticher, O., Çalis, I.; Triterpene saponins from the fruits of Hedera helix; Phytochemistry, (2000); 53: 905-909
7. Christensen, L.P., Lam, J., Thomasen, T.; Polyacetylenes from the fruits of Hedera helix; Phytochemistry, (1991); 30: 4151-4152
8. Sieben, A., Prenner, L., Sorkalla, T., Wolf, A., Jakobs, D., Runkel, F., et al.; a-Hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of b2-Adrenergic receptors; Biochemistry, (2009); 48: 3477-3482
9. European Directorate for the Quality of Medicines & Healthcare; European pharmacopoeia; 8th ed., (2014), pp. 1448-1449
10. National Institute of Food and Drug Safety Evaluation; Korean pharmaceutical codex; 3rd ed., Ministry of Food and Drug Safety, Seoul, (2007), pp. 50-51
11. Demirci, B., Goppel, M., Demirci, F., Franz, G.; HPLC profiling and quantification of active principles in leaves of Hedera helix L.; Die Pharmazie, (2004); 59: 770-774
12. Gaillard, Y., Blaise, P., Darre, A., Barbier, T., Pepin, G.; An unusual case of death: suffocation caused by leaves of common ivy (Hedera helix). Detection of hederacoside C, a-hederin, and hederagenin by LC-EI/MS-MS; Journal of Analytical Toxicology, (2003); 27: 257-262
13. Trute, A., Nahrstedt, A.; Identification and quantitative analysis of phenolic compounds from the dry extract of Hedera helix; Planta Medica, (1997); 63: 177-179
14. Sekine T., Arita, J., Yamaguchi, A., Saito, K., Okonogi, S., Morisaki, N., et al.; Two flavonol glycosides from seeds of Camellia sinensis; Phytochemistry, (1991); 30: 991-995
15. Sano, K., Sanada, S., Ida, Y., Shoji, J.; Studies on the constituents of the bark of Kalopanax pictus NAKAI; Chemical & Pharmaceutical Bulletin, (1991); 39: 865-870
16. Ding, Q., Yang, L.X., Yang, H.W., Jiang, C., Wang, Y.F., Wang, S.; Cytotoxic and antibacterial triterpenoids derivatives from Clematis ganpiniana; Journal of Ethnopharmacology, (2009); 126: 382-385
17. Cui, H., He, C., Zhao, G.; Determination of polyphenols by highperformance liquid chromatography with inhibited chemiluminescence detection; Journal of chromatography A, (1999); 855: 171-179
18. Oleszek, W., Bialy, Z.; Chromatographic determination of plant saponins-An update (2002-2005); Journal of chromatography A, (2006); 1112: 78-91
19. Khdair, A., Mohammad, M.K., Tawaha, K., Al-Hamarsheh, E., AlKhatib, H.S., Al-khalidi, B., et al.; A validated RP HPLC-PAD method for the determination of hederacoside C in ivy-Thyme cough syrup; International Journal of Analytical Chemistry, (2010); 1-5, Article ID 478143