An unusual case of death: Suffocation caused by leaves of common ivy (Hedera helix). Detection of hederacoside C, α-hederin, and hederagenin by LC-EI/MS

Journal of Analytical Toxicology

Volumn 27, Issue 4, 2003, Pages 257-262

  Gaillard, Yvan ^a   Blaise, Pierre ^b   Darré, Alexandre ^a   Barbier, Thierry ^b   Pépin, Gilbert ^a  

^a Laboratoire d'Expertises TOXLAB   (France)

^b Thermo Finnigan France   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HEDERIN; HEDELIX; HEDERACOSIDE C; HEDERAGENIN; SAPONIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASPHYXIA; AUTOPSY; BODY FLUID; CAUSE OF DEATH; CLINICAL FEATURE; HUMAN; INTOXICATION; IVY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; PLANT; QUANTITATIVE ANALYSIS; SOLID PHASE EXTRACTION; STOMACH JUICE; SUICIDE;

HEDERA; HEDERA HELIX;

EID: 0038620221     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/27.4.257     Document Type: Article

References (16)

1. J. Bruneton. Plantes Toxiques. Végétaux Dangereux Pour l'Homme et les Animaux. Lavoisier, Paris, France, 1996.
2. F. Couplan. Les Belles Vénéneuses. Plantes Sauvages Toxiques. Equilibre, Flers, France, 1990.
3. A.M. Debelmas and M. Delaveau. Guide des Plantes Dangereuses, 2nd ed. Maloine, Paris, France, 1983.
4. E. Bedir, H. Kirmizipekmez, O Sticher, and I. Calis. Triterpene saponins from the fruit of Hedera helix. Phytochemistry 53: 905-909 (2000).
5. H.M. Zhong, C.X. Chen, X. Tian, Y.X. Chui, and Y.Z. Chen. Triterpenoid saponins from Clematis tangutica. Planta Med. 67; 484-488 (2001).
6. C. Lavaud, M.L. Crubbet, I. Pouny, M. Litaudon, and T. Sevenet. Triterpenoid saponins from the stem bark of Elattostachys apetala. Phytochemistry 57: 469-478 (2001).
7. W.J. Sun, D.K. Zhang, Z.F. Sha, H.L. Zhang, and X.L. Zhang. Studies on the saponin constituents of Kalopanax septembolus (Thumb.) koidz. Yao Xue Xue Bao 25: 29-34 (1990).
8. Q. Mao and X.S. Jia. Studies on the chemical constituents of Lonicera fulvotomentosa Hsu et SC Cheng. Yao Xue Xue Bao 24: 269-274 (1989).
9. A. Trute, J. Gross, E. Mutschler, and A. Nahrstedt. In vitro anti-spasmodic compounds of the dry extract obtained from Hedera helix. Planta Med. 63: 125-129 (1997).
10. P. Timon-David, J. Julien, M. Gasquet, G. Balansart, and P. Bernard. Research of antifungal activity from several active principle extracts from climbing ivy: Hedera helix. Ann. Pharm. Fr. 38: 545-549 (1980).
11. J. Julien, M. Gasquet, C. Maillard, and P. Timon-David. Extracts of the ivy plant Hedera helix and their anthelmintic activity on the liver flukes. Planta Med. 51: 25-32 (1985).
12. S.S. Muthu Kamara and B. Tan Kwong Huat. Extraction, isolation and characterization of antitumor principle, a-hederin, from the seeds of Nigella sativa. Planta Med. 67: 29-32 (2001).
13. G. Gault. Epidémiologie des intoxications végétales chez les animaux domestiques et sauvages à partir des données du CNITV-Lyon de 1990 à 1992. Etude de la toxicologie de quelques plantes. Thesis, University CI. Bernard, Lyon, France, 1993.
14. Y. Gaillard and G. Pépin. Screening and identification of drugs in human hair by high-performance liquid chromatography-photodiode array detection and gas chromatography-mass spectrometry after solid phase extraction. A powerful tool in forensic medicine. J. Chromatogr. A 762: 251-267 (1997).
15. Y. Gaillard, and G. Pépin. Testing hair for pharmaceuticals. J. Chromatogr. B 733: 231-246 (1999).
16. Y. Gaillard, C. Peyrefitte, V. Cheminel, J.M. Prévosto, and J.F. Chaulet. Stratégie de validation de méthode: hypothèse de linéarité et intérêt du test de Hartley dans le choix de la régression linéaire-pondérée ou non-pondérée. Exemple du dosage plasmatique du midazolam par HPLC. Lyon Pharmaceutique 46/2: 67-78 (1995).