Preoperative Neutrophil-to-Lymphocyte Ratio and Neutrophilia Are Independent Predictors of Recurrence in Patients with Localized Papillary Renal Cell Carcinoma

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Huang, Jiwei ^a   Dahl, Douglas M ^b   Dong, Liang ^a   Liu, Qiang ^a   Cornejo, Kristine ^b   Wang, Qi ^c   Wu, Shulin ^b   Feldman, Adam S ^b   Huang, Yiran ^a   Xue, Wei ^a   Wu, Chin Lee ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSOLUTE LYMPHOCYTE COUNT; ABSOLUTE NEUTROPHIL COUNT; ADULT; ARTICLE; CANCER LOCALIZATION; CANCER PATIENT; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SIZE; CANCER STAGING; CANCER SURVIVAL; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; KIDNEY CARCINOMA; LYMPH NODE METASTASIS; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL COUNT; NEUTROPHIL LYMPHOCYTE RATIO; NEUTROPHILIA; PAPILLARY CARCINOMA; PAPILLARY RENAL CELL CARCINOMA; PARTIAL NEPHRECTOMY; PREOPERATIVE CARE; PREOPERATIVE PERIOD; RECURRENCE FREE SURVIVAL; RETROSPECTIVE STUDY; TUMOR NECROSIS; CARCINOMA, RENAL CELL; CLINICAL TRIAL; INCIDENCE; KIDNEY NEOPLASMS; LEUKOCYTE COUNT; LEUKOCYTE DISORDERS; LYMPHOCYTE; MASSACHUSETTS; MIDDLE AGED; MULTICENTER STUDY; NEUTROPHIL; PATHOLOGY; PROCEDURES; PROGNOSIS; REPRODUCIBILITY; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; STATISTICS AND NUMERICAL DATA; TUMOR RECURRENCE;

BOSTON; CARCINOMA, RENAL CELL; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; INCIDENCE; KIDNEY NEOPLASMS; LEUKOCYTE COUNT; LEUKOCYTE DISORDERS; LYMPHOCYTES; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEUTROPHILS; PREOPERATIVE CARE; PROGNOSIS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

EID: 84941619666     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/891045     Document Type: Article

References (23)

1. J. C. Cheville, C. M. Lohse, H. Zincke, A. L. Weaver, and M. L. Blute, "Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma,"American Journal of Surgical Pathology, vol. 27, no. 5, pp. 612-624, 2003.
2. P. E. Teloken, R. H. Thompson, S. K. Tickoo et al., "Prognostic impact of histological subtype on surgically treated localized renal cell carcinoma," The Journal of Urology, vol. 182, no. 5, pp. 2132-2136, 2009.
3. T. Klatte and A. J. Pantuck, "Molecular biology of renal cortical tumors," Urologic Clinics of North America, vol. 35, no. 4, pp. 573-580, 2008.
4. T. Klatte, J. S. Lam, B. Shuch, A. S. Belldegrun, andA. J. Pantuck, "Surveillance for renal cell carcinoma: why and how? When and how often?" Urologic Oncology: Seminars and Original Investigations, vol. 26, no. 5, pp. 550-554, 2008.
5. M. W. Kattan, V. Reuter, R. J. Motzer, J. Katz, and P. Russo, "A postoperative prognostic nomogram for renal cell carcinoma," The Journal of Urology, vol. 166, no. 1, pp. 63-67, 2001.
6. A. Zisman, A. J. Pantuck, F.Dorey et al., "Improved prognostication of renal cell carcinoma using an integrated staging system," Journal of Clinical Oncology, vol. 19, no. 6, pp. 1649-1657, 2001.
7. B. C. Leibovich, M. L. Blute, J. C. Cheville et al., "Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: a stratification tool for prospective clinical trials," Cancer, vol. 97, no. 7, pp. 1663-1671, 2003.
8. C. S. D. Roxburgh and D. C. McMillan, "Role of systemic inflammatory response in predicting survival in patients with primary operable cancer," Future Oncology, vol. 6, no. 1,pp. 149-163, 2010.
9. Y. Ohno, J. Nakashima, M. Ohori, T.Hatano, and M. Tachibana, "Pretreatment neutrophil-to-lymphocyte ratio as an independent predictor of recurrence in patients with nonmetastatic renal cell carcinoma," Journal of Urology, vol. 184, no. 3, pp. 873-878, 2010.
10. M. Pichler, G. C. Hutterer, C. Stoeckigt et al., "Validation of the pre-treatment neutrophil-lymphocyte ratio as a prognostic factor in a large European cohort of renal cell carcinoma patients," British Journal of Cancer, vol. 108, no. 4, pp. 901-907, 2013.
11. S. Saroha, R. G. Uzzo, E. R. Plimack, K. Ruth, and T. Al-Saleem, "Lymphopenia is an independent predictor of inferior outcome in clear cell renal carcinoma," Journal of Urology, vol. 189, no. 2, pp. 454-460, 2013.
12. Y. Ohno, J. Nakashima, M. Ohori, T. Gondo, T. Hatano, and M. Tachibana, "Followup of neutrophil-to-lymphocyte ratio and recurrence of clear cell renal cell carcinoma," Journal of Urology, vol. 187, no. 2, pp. 411-417, 2012.
13. M. de Martino, A. J. Pantuck, S. Hofbauer et al., "Prognostic impact of preoperative neutrophil-to-lymphocyte ratio in localized nonclear cell renal cell carcinoma," The Journal of Urology, vol. 190, no. 6, pp. 1999-2004, 2013.
14. R. Mehrazin, R. G. Uzzo, A. Kutikov et al., "Lymphopenia is an independent predictor of inferior outcomein papillary renal cell carcinoma," Urologic Oncology, 2014.
15. G.Novara, V. Ficarra, A. Antonelli et al., "Validation of the 2009 TNM version in a large multi-institutional cohort of patients treated for renal cell carcinoma: are further improvements needed?" European Urology, vol. 58, pp. 588-595, 2010.
16. S. A. Fuhrman, L. C. Lasky, and C. Limas, "Prognostic significance of morphologic parameters in renal cell carcinoma," American Journal of Surgical Pathology, vol. 6, no. 7, pp. 655-663, 1982.
17. B. Delahunt and J. N. Eble, "Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors," Modern Pathology, vol. 10, no. 6, pp. 537-544, 1997.
18. F. E. Harrell Jr., R. M. Califf, D. B. Pryor, K. L. Lee, and R. A. Rosati, "Evaluating the yield of medical tests," The Journal of the American Medical Association, vol. 247, no. 18, pp. 2543-2546, 1982.
19. Y.Yuan, E.M.Van Allen, L.Omberg et al., "Assessing the clinical utility of cancer genomic and proteomic data across tumor types," Nature Biotechnology, vol. 32, no. 7, pp. 644-652, 2014.
20. M. Gerlinger, A. J. Rowan, S. Horswell et al., "Intratumor heterogeneity and branched evolution revealed by multiregion sequencing,"The New England Journal ofMedicine, vol. 366, no. 10, pp. 883-892, 2012.
21. M. deMartino, T.Klatte,C. Seemann et al., "Validation of serum C-reactive protein (CRP) as an independent prognostic factor for disease-free survival in patients with localised renal cell carcinoma (RCC)," BJU International, vol. 111, no. 8, pp. E348-E353, 2013.
22. L. M. Coussens and Z. Werb, "Inflammation and cancer," Nature, vol. 420, no. 6917, pp. 860-867, 2002.
23. H. K. Jensen, F. Donskov, N. Marcussen, M. Nordsmark, F. Lundbeck, and H. von der Maase, "Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma," Journal of Clinical Oncology, vol. 27, no. 28, pp. 4709-4717, 2009.