Clostridium difficile infections before and during use of ultraviolet disinfection

American Journal of Infection Control

Volumn 43, Issue 9, 2015, Pages 940-945

  Nagaraja, Aarathi ^a   Visintainer, Paul ^b   Haas, Janet P ^a,c   Menz, Jonathan ^c   Wormser, Gary P ^a   Montecalvo, Marisa A ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WESTCHESTER MEDICAL CENTER   (United States)

Author keywords

Clostridium difficile; Hospital acquired; Ultraviolet disinfection

Indexed keywords

ADULT; ARTICLE; CHILD; CLOSTRIDIUM DIFFICILE INFECTION; COMMUNITY ACQUIRED INFECTION; DISINFECTION; HOSPITAL BED UTILIZATION; HOSPITAL DISCHARGE; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; NONHUMAN; PEDIATRIC WARD; PEPTOCLOSTRIDIUM DIFFICILE; RADIATION EQUIPMENT; ULTRAVIOLET DISINFECTION; ULTRAVIOLET RADIATION; CLOSTRIDIUM INFECTION; CROSS INFECTION; PROCEDURES; RADIATION RESPONSE;

XENON;

CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; CROSS INFECTION; DISINFECTION; HUMANS; ULTRAVIOLET RAYS; XENON;

EID: 84941599004     PISSN: 01966553     EISSN: 15273296     Source Type: Journal    
DOI: 10.1016/j.ajic.2015.05.003     Document Type: Article

References (38)

1. V.G. Loo, L. Poirier, M.A. Miller, M. Oughton, M.D. Libman, S. Michaud, and et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality N Engl J Med 353 2005 2442 2449
2. D.N. Gerding, C.A. Muto, and R.C. Owens Jr. Measures to control and prevent Clostridium difficile infection Clin Infect Dis 46 Suppl 2008 S43 S49
3. S.K. Abbett, D.S. Yokoe, S.R. Lipsitz, A.M. Bader, W.R. Berry, E.M. Tamplin, and et al. Proposed checklist of hospital interventions to decrease the incidence of healthcare-associated Clostridium difficile infection Infect Control Hosp Epidemiol 30 2009 1062 1069
4. L.V. McFarland, M.E. Mulligan, R.Y. Kwok, and W.E. Stamm Nosocomial acquisition of Clostridium difficile infection N Engl J Med 320 1989 204 210
5. L.V. McFarland What's lurking under the bed? Persistence and predominance of particular Clostridium difficile strains in a hospital and the potential role of environmental contamination Infect Control Hosp Epidemiol 23 2002 639 640
6. M.M. Riggs, A.K. Sethi, T.F. Zabarsky, E.C. Eckstein, R.L. Jump, and C.J. Donskey Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents Clin Infect Dis 45 2007 992 998
7. G.S. Bobulsky, W.N. Al-Nassir, M.M. Riggs, A.K. Sethi, and C.J. Donskey Clostridium difficile skin contamination in patients with C. difficile-associated disease Clin Infect Dis 46 2008 447 450
8. F. Trillis 3rd, E.C. Eckstein, R. Budavich, M.J. Pultz, and C.J. Donskey Contamination of hospital curtains with healthcare-associated pathogens Infect Control Hosp Epidemiol 29 2008 1074 1076
9. R.K. Vajravelu, D.M. Guerrero, L.A. Jury, and C.J. Donskey Evaluation of stethoscopes as vectors of Clostridium difficile and methicillin-resistant Staphylococcus aureus Infect Control Hosp Epidemiol 33 2012 96 98
10. D.M. Guerrero, M.M. Nerandzic, L.A. Jury, S. Jinno, S. Chang, and C.J. Donskey Acquisition of spores on gloved hands after contact with the skin of patients with Clostridium difficile infection and with environmental surfaces in their rooms Am J Infect Control 40 2012 556 558
11. L.A. Jury, D.M. Guerrero, C.J. Burant, J.L. Cadnum, and C.J. Donskey Effectiveness of routine patient bathing to decrease the burden of spores on the skin of patients with Clostridium difficile infection Infect Control Hosp Epidemiol 32 2011 181 184
12. A.K. Sethi, W.N. Al-Nassir, M.M. Nerandzic, G.S. Bobulsky, and C.J. Donskey Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection Infect Control Hosp Epidemiol 31 2010 21 27
13. S. Jinno, S. Kundrapu, D.M. Guerrero, L.A. Jury, M.M. Nerandzic, and C.J. Donskey Potential for transmission of Clostridium difficile by asymptomatic acute care patients and long-term care facility residents with prior C. difficile infection Infect Control Hosp Epidemiol 33 2012 638 639
14. M.K. Shaughnessy, R.L. Micielli, D.D. DePestel, J. Arndt, C.L. Strachan, K.B. Welch, and et al. Evaluation of hospital room assignment and acquisition of Clostridium difficile infection Infect Control Hosp Epidemiol 32 2011 201 206
15. K.H. Kim, R. Fekety, D.H. Batts, D. Brown, M. Cudmore, J. Silva Jr., and et al. Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-associated colitis J Infect Dis 143 1981 42 50
16. S.H. Cohen, D.N. Gerding, S. Johnson, C.P. Kelly, V.G. Loo, L.C. McDonald, and et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA) Infect Control Hosp Epidemiol 31 2010 431 455
17. J.L. Mayfield, T. Leet, J. Miller, and L.M. Mundy Environmental control to reduce transmission of Clostridium difficile Clin Infect Dis 31 2000 995 1000
18. P.C. Carling, S. Von Beheren, P. Kim, C. Woods Healthcare Environmental Hygiene Study Group Intensive care unit environmental cleaning: an evaluation in sixteen hospitals using a novel assessment tool J Hosp Infect 68 2008 39 44
19. B.C. Eckstein, D.A. Adams, E.C. Eckstein, A. Rao, A.K. Sethi, G.K. Yadavalli, and et al. Reduction of Clostridium Difficile and vancomycin-resistant Enterococcus contamination of environmental surfaces after an intervention to improve cleaning methods BMC Infect Dis 7 2007 61
20. B. Sitzlar, A. Deshpande, D. Fertelli, S. Kundrapu, A.K. Sethi, and C.J. Donskey An environmental disinfection odyssey: evaluation of sequential interventions to improve disinfection of Clostridium difficile isolation rooms Infect Control Hosp Epidemiol 34 2013 459 465
21. D.M. Guerrero, P.C. Carling, L.A. Jury, S. Ponnada, M.M. Nerandzic, and C.J. Donskey Beyond the Hawthorne effect: reduction of Clostridium difficile environmental contamination through active intervention to improve cleaning practices Infect Control Hosp Epidemiol 34 2013 524 526
22. S. Kundrapu, V. Sunkesula, L.A. Jury, B.M. Sitzlar, and C.J. Donskey Daily disinfection of high-touch surfaces in isolation rooms to reduce contamination of healthcare workers' hands Infect Control Hosp Epidemiol 33 2012 1039 1042
23. C.J. Donskey Preventing transmission of Clostridium difficile: is the answer blowing in the wind? Clin Infect Dis 50 2010 1458 1461
24. D.J. Weber, and W.A. Rutala Understanding and preventing transmission of healthcare-associated pathogens due to the contaminated hospital environment Infect Control Hosp Epidemiol 34 2013 449 452
25. N.M. Nerandzic, J.I. Cadnum, M.J. Pultz, and C.J. Donsky Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms BMC Infect Dis 10 2010 197
26. V.K. Rastogi, L. Wallace, and L.S. Smith Disinfection of Acinetobacter baumannii- contaminated surfaces relevant to medical treatment facilities with ultraviolet C light Mil Med 172 2007 1166 1169
27. W.A. Rutala, M.F. Gergen, and D.J. Weber Room decontamination with UV radiation Infect Control Hosp Epidemiol 31 2010 1025 1029
28. J.M. Boyce, N.L. Havill, and B.A. Moore Terminal decontamination of patient rooms using an automated mobile UV light unit Infect Control Hosp Epidemiol 32 2011 737 742
29. M.M. Nerandzic, J.L. Cadnum, K.E. Eckart, and C.J. Donskey Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens BMC Infect Dis 12 2012 120
30. B. Sitzlar, R.K. Vajravelu, L. Jury, C.J. Donskey, and R.L. Jump Environmental decontamination with ultraviolet radiation to prevent recurrent Clostridium difficile infection in 2 roommates in a long-term care facility Infect Control Hosp Epidemiol 33 2012 534 536
31. M. Stibich, J. Stachowiak, B. Tanner, M. Berkheiser, L. Moore, I. Raad, and et al. Evaluation of a pulsed-xenon ultraviolet room disinfection device for impact on hospital operations and microbial reduction Infect Control Hosp Epidemiol 32 2011 286 288
32. J.P. Haas, J. Menz, P. Ortiz, and M.A. Montecalvo Implementation and impact of ultraviolet environmental disinfection in an acute care setting Am J Infect Control 42 2014 586 590
33. B. Rosner Fundamentals of Biostatistics 6th ed. 2006 Duxbury Press Belmont, CA
34. New York State Department of Health. Hospital-acquired infections: New York State 2013. Available from: https://www.health.ny.gov/statistics/facilities/hospital/hospital-acquired-infections/2013/docs/hospital-acquired-infection.pdf. January 31, 2015.
35. E.R. Dubberke, K.A. Reske, M.A. Olsen, K.M. McMullen, J.L. Mayfield, L.C. McDonald, and et al. Evaluation of Clostridium difficile -associated disease pressure as a risk factor for C. difficile-associated disease Arch Intern Med 167 2007 1092 1097
36. D.W. Eyre, M.L. Cule, D.J. Wilson, D. Griffiths, A. Vaughan, L. O'Connor, and et al. Diverse sources of C. difficile infection identified on whole-genome sequencing N Engl J Med 369 2013 1195 1205
37. Xenex. Reducing healthcare associated infections (HAIs): not all UV light is the same. Available from: http://www.xenex.com/article/reducing-healthcare-associated-infections-hais-uv-light. January 31, 2015.
38. M.M. Nerandzic, P. Thota, C.T. Sankar, A. Jencson, J.L. Cadnum, A.J. Ray, and et al. Evaluation of a pulsed xenon ultraviolet disinfection system for reduction of healthcare-associated pathogens in hospital rooms Infect Control Hosp Epidemiol 36 2015 192 197