Evaluation of a pulsed xenon ultraviolet disinfection system for reduction of healthcare-associated pathogens in hospital rooms

Infection Control and Hospital Epidemiology

Volumn 36, Issue 2, 2015, Pages 192-197

  Nerandzic, Michelle M ^a   Thota, Priyaleela ^b   Sankar C, Thriveen ^b   Jencson, Annette ^a   Cadnum, Jennifer L ^b   Ray, Amy J ^b,c   Salata, Robert A ^b,c   Watkins, Richard R ^d   Donskey, Curtis J ^a,b,c  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^d AKRON GENERAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL SPORE; COLONY FORMING UNIT; DISINFECTION SYSTEM; ENVIRONMENTAL EXPOSURE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL CONTAMINATION; NONHUMAN; PATHOGEN CLEARANCE; PATHOGEN LOAD; PEPTOCLOSTRIDIUM DIFFICILE; PULSED XENON ULTRAVIOLET DISINFECTION SYSTEM; RECOVERY ROOM; ULTRAVIOLET IRRADIATION; VANCOMYCIN RESISTANT ENTEROCOCCUS; BACTERIAL COUNT; CROSS INFECTION; DISINFECTION; EVALUATION STUDY; FOMITE; HEALTH CARE FACILITY; MICROBIOLOGY; PROCEDURES; RADIATION RESPONSE; TIME; ULTRAVIOLET RADIATION;

XENON;

CLOSTRIDIUM DIFFICILE; COLONY COUNT, MICROBIAL; CROSS INFECTION; DISINFECTION; FOMITES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PATIENTS' ROOMS; SPORES, BACTERIAL; TIME FACTORS; ULTRAVIOLET RAYS; VANCOMYCIN-RESISTANT ENTEROCOCCI; XENON;

EID: 84922702269     PISSN: 0899823X     EISSN: 15596834     Source Type: Journal    
DOI: 10.1017/ice.2014.36     Document Type: Article

References (22)

1. Conner-Kerr TA, Sullivan PK, Gaillard J, Jones RM. The effects of ultraviolet radiation on antibiotic-resistant bacteria in vitro. Ostomy Wound Manage 1998;44:50-56.
2. Griego VM, Spence KD. Inactivation of Bacillus thuringiensis spores by ultraviolet and visible light. Appl Env Microbiol 1977;35:906-910.
3. Hercik F. Action of ultraviolet light on spores and vegetative forms of Bacillus megatherium sp. J Gen Physiol 1936;20:589-594.
4. Setlow P. Spores of Bacillus subtilis: their resistance to and killing by radiation, heat and chemicals. J Appl Microbiol 2006;101:514-525.
5. Setlow P. Resistance of spores of Bacillus species to ultraviolet light. Environ Mol Mutagen 2001;38:97-104.
6. Thai TP, Keast DH, Campbell KE, Woodbury MG, Houghton PE. Effect of ultraviolet light C on bacterial colonization in chronic wounds. Ostomy Wound Manage 2005;51:32-45.
7. Owens MU, Deal DR, Shoemaker MO, et al. High-dose ultra-violet C light inactivates spores of Bacillus subtilis var. niger and Bacillus anthracis Sterne on non-reflective surfaces. Appl Biosafety 2005;10:240-247.
8. Jinadatha C, Quezada R, Huber TW, Williams JB, Zeber JE, Copeland LA. Evaluation of a pulsed-xenon ultraviolet room disinfection device for impact on contamination levels of methicillin-resistant Staphylococcus aureus. BMC Infect Dis 2014;14:187.
9. Levin J, Riley LS, Parrish C, English D, Ahn S. The effect of portable pulsed xenon ultraviolet light after terminal cleaning on hospital-associated Clostridium difficile infection in a community hospital. Am J Infect Control 2013;41:746-748.
10. Otaki M, Okuda A, Tajima K, Iwasaki T, Kinoshita S, Ohgaki S. Inactivation differences of microorganisms by low pressure UV and pulsed xenon lamps. Water Sci Technol 2003; 47:185-190.
11. Stibich M, Stachowiak J, Tanner B, et al. Evaluation of a pulsed-xenon ultraviolet room disinfection device for impact on hospital operations and microbial reduction. Infect Control Hosp Epidemiol 2011;32:286-288.
12. Umezawa K, Asai S, Inokuchi S, Miyachi H. A comparative study of the bactericidal activity and daily disinfection housekeeping surfaces by a new portable pulsed UV radiation device. Curr Microbiol 2012;64:581-587.
13. Nerandzic MM, Cadnum JL, Pultz MJ, Donskey CJ. Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms. BMC Infect Dis 2010;10:197.
14. Sorg JA, Sonenshein AL. Bile salts and glycine as cogerminants for Clostridium difficile spores. J Bacteriol 2008;190(7):2505-2512.
15. Nerandzic MM, Donskey CJ. Effective and reduced-cost modified selective medium for isolation of Clostridium difficile. J Clin Microbiol 2009;47(2):397-400.
16. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, M7. Wayne, PA: Clinical and Laboratory Institute, 2005.
17. Nerandzic MM, Cadnum JL, Eckart KE, Donskey CJ. Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens. BMC Infect Dis 2012;12:120.
18. Nerandzic MM, Fisher CW, Donskey CJ. Sorting through the wealth of options: Comparative evaluation of 2 ultraviolet disinfection systems. PLOS ONE, 9:e107444.
19. Zhang A, Nerandzic MM, Kundrapu S, Donskey CJ. Does organic material on hospital surfaces reduce the effectiveness of hypochlorite and UV radiation for disinfection of Clostridium difficile? Infect Control Hosp Epidemiol 2013;34:1106-1108.
20. Barbut F, Menuet D, Verachten M, Girou E. Comparison of the efficacy of a hydrogen peroxide dry-mist disinfection system and sodium hypochlorite solution for reduction of Clostridium difficile spores. Infect Control Hosp Epidemiol 2009;30:507-514.
21. Boyce JM, Havill NL, Otter JA, et al. Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting. Infect Control Hosp Epidemiol 2008;29:723-729.
22. Haas JP, Menz J, Dusza S, Montecalvo MA. Implementation and impact of ultraviolet environmental disinfection in an acute care setting. Am J Infect Control 2014;42:586-590.