Association of HIV, hepatitis C virus and liver fibrosis severity with interleukin-6 and C-reactive protein levels

AIDS

Volumn 29, Issue 11, 2015, Pages 1325-1333

  Shah, Shailja ^a   Ma, Yifei ^b   Scherzer, Rebecca ^a,c   Huhn, Greg ^d   French, Audrey L ^d   Plankey, Michael ^e   Peters, Marion G ^a   Grunfeld, Carl ^a,c   Tien, Phyllis C ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d RUSH MEDICAL COLLEGE   (United States)

^e GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

C reactive protein; hepatitis C virus; HIV; IL 6; transient elastography

Indexed keywords

ALANINE AMINOTRANSFERASE; APOLIPOPROTEIN B; ASPARTATE AMINOTRANSFERASE; C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VIRUS RNA; C-REACTIVE PROTEIN RECEPTOR, HUMAN; IL6 PROTEIN, HUMAN; IMMUNOGLOBULIN RECEPTOR;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CANNABIS USE; CD4 LYMPHOCYTE COUNT; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; CORRELATION ANALYSIS; DISEASE SEVERITY; ELASTOGRAPHY; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIMIT OF DETECTION; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MIXED INFECTION; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; SMOKING; TRIACYLGLYCEROL BLOOD LEVEL; VIRUS REPLICATION; WAIST CIRCUMFERENCE; BLOOD; CHRONIC HEPATITIS C; COMPLICATION; GENETICS; HEPACIVIRUS; LIVER CIRRHOSIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL;

ADULT; COINFECTION; ELASTICITY IMAGING TECHNIQUES; FEMALE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HIV INFECTIONS; HUMANS; INTERLEUKIN-6; LINEAR MODELS; LIVER CIRRHOSIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROSPECTIVE STUDIES; RECEPTORS, IMMUNOLOGIC; SEVERITY OF ILLNESS INDEX;

EID: 84941564162     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0000000000000654     Document Type: Article

References (31)

1. Freiberg MS, Chang CC, Skanderson M, McGinnis K, Kuller LH, Kraemer KL, et al. The risk of incident coronary heart disease among veterans with and without HIV and hepatitis C. Circ Cardiovasc Qual Outcomes 2011; 4:425-432.
2. Bedimo R, Westfall AO, Mugavero M, Drechsler H, Khanna N, Saag M. Hepatitis C virus coinfection and the risk of cardiovascular disease among HIV-infected patients. HIV Med 2010; 11:462-468.
3. Butt AA, McGinnis K, Rodriguez-Barradas MC, Crystal S, Simberkoff M, Goetz MB, et al. HIV infection and the risk of diabetes mellitus. AIDS 2009; 23:1227-1234.
4. Tsui JI, Whooley MA, Monto A, Seal K, Tien PC, Shlipak M. Association of hepatitis C virus seropositivity with inflammatory markers and heart failure in persons with coronary heart disease: data from the Heart and Soul study. J Card Fail 2009; 15:451-456.
5. Oliveira CP, Kappel CR, Siqueira ER, Lima VM, Stefano JT, Michalczuk MT, et al. Effects of hepatitis C virus on cardiovascular risk in infected patients: a comparative study. Int J Cardiol 2013; 164:221-226.
6. Danesh J, Kaptoge S, Mann AG, Sarwar N, Wood A, Angleman SB, et al. Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review. PLoS Med 2008; 5:e78.
7. Lee JK, Bettencourt R, Brenner D, Le TA, Barrett-Connor E, Loomba R. Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study. PLoS One 2012; 7:e34218.
8. Volpato S, Guralnik JM, Ferrucci L, Balfour J, Chaves P, Fried LP, et al. Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study. Circulation 2001; 103:947-953.
9. Salter ML, Lau B, Mehta SH, Go VF, Leng S, Kirk GD. Correlates of elevated interleukin-6 and C-reactive protein in persons with or at high risk for HCV and HIV infections. J Acquir Immune Defic Syndr 2013; 64:488-495.
10. Reingold J, Wanke C, Kotler D, Lewis C, Tracy R, Heymsfield S, et al. Association of HIV infection and HIV/HCV coinfection with C-reactive protein levels: the fat redistribution and metabolic change in HIV infection (FRAM) study. J Acquir Immune Defic Syndr 2008; 48:142-148.
11. Arciello M, Petta S, Leoni V, Iannucci G, Labbadia G, Camma C, et al. Inverse correlation between plasma oxysterol and LDLcholesterol levels in hepatitis C virus-infected patients. Dig Liver Dis 2012; 44:245-250.
12. Syed GH, Amako Y, Siddiqui A. Hepatitis C virus hijacks host lipid metabolism. Trends Endocrinol Metab 2010; 21:33-40.
13. Bacon MC, Von Wyl V, Alden C, Sharp G, Robison E, Hessol N, et al. The Women's Interagency HIV Study: an observational cohort brings clinical sciences to the bench. Clin Diagn Lab Immunol 2005; 12:1013-1019.
14. Barkan SE, Melnick SL, Preston-Martin S, Weber K, Kalish LA, Miotti P, et al. The women's interagency HIV study. Epidemiology 1998; 9:117-125.
15. Bailony MR, Scherzer R, Huhn G, Plankey MW, Peters MG, Tien PC. Association of HIV infection, hepatitis C virus infection, and metabolic factors with liver stiffness measured by transient elastography. J Infect Dis 2013; 208:1776-1783.
16. Gilks WR, Richardson S, Spiegelhalter DJ. Markov chain Monte Carlo in practice. London: Chapman & Hall; 1996.
17. Vergara S, Mac?ás J, Rivero A, Gutiérrez-Valencia A, González-Serrano M, Merino D, et al. The use of transient elastometry for assessing liver fibrosis in patients with HIV and hepatitis Cvirus coinfection. Clin InfectDis 2007; 45:969-974.
18. Kirk GD, Astemborski J, Mehta SH, Spoler C, Fisher C, Allen D, et al. Assessment of liver fibrosis by transient elastography in persons with hepatitis C virus infection or HIV-hepatitis C virus coinfection. Clin Infect Dis 2009; 48:963-972.
19. Manning WG, Mullahy J. Estimating log models: to transform or not to transform? J Health Econ 2001; 20:461-494.
20. Santos Silva J, Tenreyro S. The log of gravity. Rev Econ Stait 2006; 88:641-658.
21. Santos Silva J, Tenreyro S. On the existence of the maximum likelihood estimates in Poisson regression. Econ Lett 2010; 107:310-312.
22. Armah KA, Quinn EK, Cheng DM, Tracy RP, Baker JV, Samet JH, et al. Human immunodeficiency virus, hepatitis C, and inflammatory biomarkers in individuals with alcohol problems: a cross-sectional study. BMC Infect Dis 2013; 13:399.
23. Fuster D, Tsui JI, Cheng DM, Quinn EK, Armah KA, Nunes D, et al. Interleukin-6 is associated with noninvasive markers of liver fibrosis in HIV-infected patients with alcohol problems. AIDS Res Hum Retroviruses 2013; 29:1110-1116.
24. Charpentier C, Champenois K, Gervais A, Landman R, Joly V, Le Gac S, et al. Predictive value of liver enzymes and inflammatory biomarkers for the severity of liver fibrosis stage in HIV/HCV co-infected patients. PLoS One 2013; 8:e59205.
25. Kalabay L, Nemesanszky E, Csepregi A, Pusztay M, David K, Horvath G, et al. Paradoxical alteration of acute-phase protein levels in patients with chronic hepatitis C treated with IFNalpha2b. Int Immunol 2004; 16:51-54.
26. Gale M Jr, Foy EM. Evasion of intracellular host defence by hepatitis C virus. Nature 2005; 436:939-945.
27. Floris-Moore M, Howard AA, Lo Y, Schoenbaum EE, Arnsten JH, Klein RS. Hepatitis C infection is associated with lower lipids and high-sensitivity C-reactive protein in HIV-infected men. AIDS Patient Care STDS 2007; 21:479-491.
28. Wheeler AL, Scherzer R, Lee D, Delaney JA, Bacchetti P, Shlipak MG, et al. HIV/hepatitis C virus coinfection ameliorates the atherogenic lipoprotein abnormalities of HIV infection. AIDS 2014; 28:49-58.
29. Lapice E, Maione S, Patti L, Cipriano P, Rivellese AA, Riccardi G, et al. Abdominal adiposity is associated with elevated C-reactive protein independent of BMI in healthy nonobese people. Diabetes Care 2009; 32:1734-1736.
30. Nakamura H, Ito H, Egami Y, Kaji Y, Maruyama T, Koike G, et al. Waist circumference is the main determinant of elevated C-reactive protein in metabolic syndrome. Diabetes Res Clin Pract 2008; 79:330-336.
31. Dolan SE, Hadigan C, Killilea KM, Sullivan MP, Hemphill L, Lees RS, et al. Increased cardiovascular disease risk indices in HIV-infected women. J Acquir Immune Defic Syndr 2005; 39: 44-54.