Assembly of human mitochondrial ATP synthase through two separate intermediates, F1-c-ring and b-e-g complex

FEBS Letters

Volumn 589, Issue 19, 2015, Pages 2707-2712

  Fujikawa, Makoto ^a,b   Sugawara, Kanako ^a,c,d   Tanabe, Tsutomu ^b   Yoshida, Masasuke ^a,d  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c JAPAN WOMEN'S UNIVERSITY   (Japan)

^d KYOTO SANGYO UNIVERSITY   (Japan)

Author keywords

Abbreviations MASC assay mitochondrial activity of SLO permeabilized cells assay; VDAC voltage dependent anion channel of mitochondria

Indexed keywords

PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; MITOCHONDRIAL PROTEIN; PROTEIN AGGREGATE; PROTEIN SUBUNIT;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; HELA CELL LINE; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; ROTOR SHAFT; STATOR STALK; BIOSYNTHESIS; CHEMISTRY; DEFICIENCY; GENE SILENCING; GENETICS; METABOLISM; PROTEIN SUBUNIT;

GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; MITOCHONDRIAL PROTEINS; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; PROTEIN AGGREGATES; PROTEIN SUBUNITS;

EID: 84941416709     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.08.006     Document Type: Article

References (23)

1. A.G. Stewart, E.M. Laming, M. Sobti, and D. Stock Rotary ATPases - dynamic molecular machines Curr. Opin. Struct. Biol. 25 2014 40 48
2. o ATPase can be purified by immunocapture from heart tissue and fibroblast cell lines. Subunit structure and activity studies J. Biol. Chem. 277 2002 33906 33912
3. B. Meyer, I. Wittig, E. Trifilieff, M. Karas, and H. Schägger Identification of two proteins associated with mammalian ATP synthase Mol. Cell. Proteomics 6 2007 1690 1699
4. M.J. Runswick, J.V. Bason, M.G. Montgomery, G.C. Robinson, I.M. Fearnley, and J.E. Walker The affinity purification and characterization of ATP synthase complexes from mitochondria Open Biol. 3 2013 120160
5. J. Hoffmann, L. Sokolova, L. Preiss, D.B. Hicks, T.A. Krulwich, N. Morgner, I. Wittig, H. Schägger, T. Meier, and B. Brutschy ATP synthases: cellular nanomotors characterized by LILBID mass spectrometry Phys. Chem. Chem. Phys. 12 2010 13375 13382
6. M. Yoshida, E. Muneyuki, and T. Hisabori ATP synthase - a marvellous rotary engine of the cell Nat. Rev. Mol. Cell Biol. 2 2001 669 677
7. 1-ATPase motor Nat. Chem. Biol. 10 2014 930 936
8. S. Ohsakaya, M. Fujikawa, T. Hisabori, and M. Yoshida Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria J. Biol. Chem. 286 2011 20292 20296
9. M. Fujikawa, S. Ohsakaya, K. Sugawara, and M. Yoshida Population of ATP synthase molecules in mitochondria is limited by available 6.8-kDa proteolipid protein (MLQ) Genes Cells 19 2014 153 160
10. I. Wittig, M. Karas, and H. Schägger High resolution clear native electrophoresis for in-gel functional assays and fluorescence studies of membrane protein complexes Mol. Cell. Proteomics 6 2007 1215 1225
11. Q.J. Bjerrum, C. Schafer-Nielsen, Buffer Systems and Transfer Parameters for Semidry Electroblotting with a Horizontal Apparatus, in Dunn M.J., (Ed.), Electrophoresis '86: Proceedings of the Fifth meeting of the International Electrophoresis Society, 1986, pp. 315-327.
12. M. Fujikawa, and M. Yoshida A sensitive, simple assay of mitochondrial ATP synthesis of cultured mammalian cells suitable for high-throughput analysis Biochem. Biophys. Res. Commun. 401 2010 538 543
13. M.D. Ginsberg, A. Feliciello, J.K. Jones, E.V. Avvedimento, and M.E. Gottesman PKA-dependent binding of mRNA to the mitochondrial AKAP121 protein J. Mol. Biol. 327 2003 885 897
14. 1-ATPase from bovine heart mitochondria Nature 370 1994 621 628
15. I.N. Watt, M.G. Montgomery, M.J. Runswick, A.G.W. Leslie, and J.E. Walker Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria Proc. Natl. Acad. Sci. U.S.A. 107 2010 16823 16827
16. L.G. Nijtmans, P. Klement, J. Houstěk, and C. van den Bogert Assembly of mitochondrial ATP synthase in cultured human cells: implications for mitochondrial diseases Biochim. Biophys. Acta 1272 1995 190 198
17. R. Carrozzo, I. Wittig, F.M. Santorelli, E. Bertini, S. Hofmann, U. Brandt, and H. Schägger Subcomplexes of human ATP synthase mark mitochondrial biosynthesis disorders Ann. Neurol. 59 2006 265 275
18. J. Houstěk, P. Klement, J. Hermanská, H. Houstková, H. Hansíková, C. van den Bogert, and J. Zeman Altered properties of mitochondrial ATP-synthase in patients with a T - >G mutation in the ATPase 6 (subunit a) gene at position 8993 of mtDNA Biochim. Biophys. Acta 1271 1995 349 357
19. L.G. Nijtmans, N.S. Henderson, G. Attardi, and I.J. Holt Impaired ATP synthase assembly associated with a mutation in the human ATP synthase subunit 6 gene J. Biol. Chem. 276 2001 6755 6762
20. D.M. Rees, A.G.W. Leslie, and J.E. Walker The structure of the membrane extrinsic region of bovine ATP synthase Proc. Natl. Acad. Sci. U.S.A. 106 2009 21597 21601
21. I. Wittig, B. Meyer, H. Heide, M. Steger, L. Bleier, Z. Wumaier, M. Karas, and H. Schägger Assembly and oligomerization of human ATP synthase lacking mitochondrial subunits a and A6L Biochim. Biophys. Acta 1797 2010 1004 1011
22. M. Rak, S. Gokova, and A. Tzagoloff Modular assembly of yeast mitochondrial ATP synthase EMBO J30 2011 920 930
23. 1 ATP synthase J. Biol. Chem. 288 2013 25880 25894