Feasibility of large-scale genomic testing to facilitate enrollment onto genomically matched clinical trials

Journal of Clinical Oncology

Volumn 33, Issue 25, 2015, Pages 2753-2762

  Meric Bernstam, Funda ^a   Brusco, Lauren ^a   Shaw, Kenna ^a   Horombe, Chacha ^a   Kopetz, Scott ^a   Davies, Michael A ^a   Routbort, Mark ^a   Piha Paul, Sarina A ^a   Janku, Filip ^a   Ueno, Naoto ^a   Hong, David ^a   De Groot, John ^a   Ravi, Vinod ^a   Li, Yisheng ^a   Luthra, Raja ^a   Patel, Keyur ^a   Broaddus, Russell ^a   Mendelsohn, John ^a   Mills, Gordon B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; K RAS PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE B; PROTEIN P53; RAS PROTEIN; AKT1 PROTEIN, HUMAN; BRAF PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3CA PROTEIN, HUMAN; PTEN PROTEIN, HUMAN; TUMOR MARKER;

ADOLESCENT; ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER GENETICS; CANCER PATIENT; CANCER THERAPY; CHEMILUMINESCENCE IMMUNOASSAY; CHILD; CLINICAL TRIAL (TOPIC); COLON CANCER; EXPERIMENTAL THERAPY; GENETIC SCREENING; GENOMICS; GENOTYPE; GERMLINE MUTATION; HUMAN; HUMAN TISSUE; LOCAL THERAPY; LUNG CANCER; MAJOR CLINICAL STUDY; MELANOMA; MULTIPLEX HOTSPOT TESTING; MUTATIONAL ANALYSIS; OBSERVATIONAL STUDY; PATIENT PREFERENCE; POINT OF CARE TESTING; PRIORITY JOURNAL; PROSPECTIVE STUDY; SOLID TUMOR; SOMATIC MUTATION; VERY ELDERLY; FEASIBILITY STUDY; FEMALE; GENETICS; MALE; MIDDLE AGED; MUTATION; NEOPLASMS; PATIENT SELECTION; PROCEDURES; TRENDS;

ADULT; AGED; BIOMARKERS, TUMOR; CLINICAL TRIALS AS TOPIC; FEASIBILITY STUDIES; FEMALE; GENETIC TESTING; GENOMICS; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASMS; PATIENT SELECTION; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE;

EID: 84941361474     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2014.60.4165     Document Type: Article

References (10)

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