A crystallin fold in the interleukin-4-inducing principle of schistosoma mansoni eggs (IPSE/α-1) mediates IgE binding for antigen-independent basophil activation

Journal of Biological Chemistry

Volumn 290, Issue 36, 2015, Pages 22111-22126

  Meyer, N Helge ^f   Mayerhofer, Hubert ^c   Tripsianes, Konstantinos ^g   Blindow, Silke ^d   Barths, Daniela ^d   Mewes, Astrid ^d   Weimar, Thomas ^e   Köhli, Thies ^e   Bade, Steffen ^d   Madl, Tobias ^h   Frey, Andreas ^d   Haas, Helmut ^d   Mueller Dieckmann, Jochen ^c   Sattler, Michael ^a,b   Schramm, Gabriele ^d  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d RESEARCH CENTER BORSTEL   (Germany)

^e UNIVERSITY OF LÜBECK   (Germany)

^f UNIVERSITY OF OLDENBURG   (Germany)

^g MASARYK UNIVERSITY   (Czech Republic)

^h MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

CRYSTALLIN; IGE BINDINGS; IMMUNE RESPONSE; INTERLEUKIN-13; INTERLEUKIN-4; NEW MEMBERS; SCHISTOSOMA MANSONI;

ANTIGENS;

CRYSTALLIN; FC RECEPTOR; HELMINTH PROTEIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 4 INDUCING PRINCIPLE FROM SCHISTOSOMA MANSONI EGG; THREONINE; TYROSINE; UNCLASSIFIED DRUG; EGG PROTEIN; INTERLEUKIN 4; IPSE PROTEIN, SCHISTOSOMA MANSONI; PARASITE ANTIGEN; PROTEIN BINDING;

ARTICLE; BASOPHIL; BINDING AFFINITY; CELL ACTIVATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; HUMAN; HUMAN CELL; HYDROPHOBICITY; MUTATIONAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; SIZE EXCLUSION CHROMATOGRAPHY; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMISTRY; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; MUTATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN ANALYSIS; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SCHISTOSOMA MANSONI; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, HELMINTH; BASOPHILS; BINDING SITES; BLOTTING, WESTERN; CHROMATOGRAPHY, GEL; CRYSTALLINS; CRYSTALLOGRAPHY, X-RAY; EGG PROTEINS; HELMINTH PROTEINS; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-4; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SCHISTOSOMA MANSONI; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84941353131     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.675066     Document Type: Article

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