Role of the Atg9a gene in intrauterine growth and survival of fetal mice

Reproductive Biology

Volumn 15, Issue 3, 2015, Pages 131-138

  Kojima, Takashi ^a   Yamada, Takahiro ^a   Akaishi, Rina ^a   Furuta, Itsuko ^a   Saitoh, Tatsuya ^b,f   Nakabayashi, Kazuhiko ^c   Nakayama, Keiichi I ^d   Nakayama, Keiko ^e   Akira, Shizuo ^b   Minakami, Hisanori ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

^e TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Autophagy; Fetal growth restriction; Hypertension; Hypoxia; Intrauterine fetal death

Indexed keywords

ATG9A PROTEIN, MOUSE; CDKN1C PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1C; MEMBRANE PROTEIN; VESICULAR TRANSPORT PROTEIN;

ALLELE; ANIMAL; AUTOPHAGY; FEMALE; FETUS DEVELOPMENT; GENETICS; HETEROZYGOTE; INTRAUTERINE GROWTH RETARDATION; KNOCKOUT MOUSE; MATERNAL HYPERTENSION; METABOLISM; MOUSE; PREGNANCY;

ALLELES; ANIMALS; AUTOPHAGY; CYCLIN-DEPENDENT KINASE INHIBITOR P57; FEMALE; FETAL DEVELOPMENT; FETAL GROWTH RETARDATION; HETEROZYGOTE; HYPERTENSION, PREGNANCY-INDUCED; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PREGNANCY; VESICULAR TRANSPORT PROTEINS;

EID: 84941318259     PISSN: 1642431X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.repbio.2015.05.001     Document Type: Article

References (24)

1. Mizushima N., Ohsumi Y., Yoshimori T. Autophagosome formation in mammalian cells. Cell Struct Funct 2002, 27:421-429.
2. Lum J.J., DeBerardinis R.J., Thompson C.B. Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol 2005, 6:439-448.
3. Xie Z., Klionsky D.J. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007, 9:1102-1109.
4. Klionsky D.J., Cregg J.M., Dunn W.A., Emr S.D., Sakai Y., Sandoval I.V., et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell 2003, 5:539-545.
5. Tsukada M., Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 1993, 333:169-174.
6. Kuma A., Hatano M., Matsui M., Yamamoto A., Nakaya H., Yoshimori T., et al. The role of autophagy during the early neonatal starvation period. Nature 2004, 432:1032-1036.
7. Komatsu M., Waguri S., Ueno T., Iwata J., Murata S., Tanida I., et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005, 169:425-434.
8. Saitoh T., Fujita N., Jang M.H., Uematsu S., Yang B.G., Satoh T., et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008, 456:264-268.
9. Saitoh T., Fujita N., Hayashi T., Takahara K., Satoh T., Lee H., et al. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc Natl Acad Sci U S A 2009, 106:20842-20846.
10. Sou Y.S., Waguri S., Iwata J., Ueno T., Fujimura T., Hara T., et al. The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice. Mol Biol Cell 2008, 19:4762-4775.
11. Albaiges G., Missfelder-Lobos H., Lees C., Parra M., Nicolaides K.H. One-stage screening for pregnancy complications by color Doppler assessment of the uterine arteries at 23 weeks' gestation. Obstet Gynecol 2000, 96:559-564.
12. Steegers E.A., von Dadelszen P., Duvekot J.J., Pijnenborg R. Pre-eclampsia. Lancet 2010, 376:631-644.
13. Contro E., Cha D.H., De Maggio I., Ismail S.Y., Falcone V., Gabrielli S., et al. Uterine artery Doppler longitudinal changes in pregnancies complicated with intrauterine growth restriction without preeclampsia. Prenat Diagn 2014, 34:1332-1336.
14. Yue Z., Jin S., Yang C., Levine A.J., Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 2003, 100:15077-15082.
15. Yamada T., Carson A.R., Caniggia I., Umebayashi K., Yoshimori T., Nakabayashi K., et al. Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast. J Biol Chem 2005, 280:18283-18290.
16. Hatada I., Mukai T. Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouse. Nat Genet 1995, 11:204-206.
17. Matsuoka S., Thompson J.S., Edwards M.C., Bartletta J.M., Grundy P., Kalikin L.M., et al. Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15. Proc Natl Acad Sci U S A 1996, 93:3026-3030.
18. Kanayama N., Takahashi K., Matsuura T., Sugimura M., Kobayashi T., Moniwa N., et al. Deficiency in p57Kip2 expression induces preeclampsia-like symptoms in mice. Mol Hum Reprod 2002, 8:1129-1135.
19. Takahashi K., Nakayama K. Mice lacking a CDK inhibitor, p57Kip2, exhibit skeletal abnormalities and growth retardation. J Biochem 2000, 127:73-83.
20. Oh S.Y., Choi S.J., Kim K.H., Cho E.Y., Kim J.H., Roh C.R. Autophagy-related proteins, LC3 and Beclin-1, in placentas from pregnancies complicated by preeclampsia. Reprod Sci 2008, 15:912-920.
21. Hung T.H., Chen S.F., Lo L.M., Li M.J., Yeh Y.L., Hsieh T.T. Increased autophagy in placentas of intrauterine growth-restricted pregnancies. PLoS ONE 2012, 7:e40957.
22. Chang Y.L., Wang T.H., Chang S.D., Chao A.S., Hsieh P.C., Wang C.N. Increased autophagy in the placental territory of selective intrauterine growth-restricted monochorionic twins. Prenat Diagn 2013, 33:187-190.
23. Curtis S., Jones C.J., Garrod A., Hulme C.H., Heazell A.E. Identification of autophagic vacuoles and regulators of autophagy in villous trophoblast from normal term pregnancies and in fetal growth restriction. J Matern Fetal Neonatal Med 2013, 26:339-346.
24. Akaishi R., Yamada T., Nakabayashi K., Nishihara H., Furuta I., Kojima T., et al. Autophagy in the placenta of women with hypertensive disorders in pregnancy. Placenta 2014, 35:974-980.