Observation of Distressed Conspecific as a Model of Emotional Trauma Generates Silent Synapses in the Prefrontal-Amygdala Pathway and Enhances Fear Learning, but Ketamine Abolishes those Effects

Neuropsychopharmacology

Volumn 40, Issue 11, 2015, Pages 2536-2545

  Ito, Wataru ^a   Erisir, Alev ^b   Morozov, Alexei ^a,c  

^a VIRGINIA TECH CARILION SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORPHENIRAMINE MALEATE PLUS PHENYLEPHRINE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; AMPA RECEPTOR; GLUTAMIC ACID; PSYCHOTROPIC AGENT;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DISTRESS SYNDROME; FEAR; GLUTAMATERGIC SYNAPSE; IMMOBILIZATION STRESS; IMMUNOREACTIVITY; LATENT PERIOD; MALE; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PSYCHOTRAUMA; REVERSAL POTENTIAL; SYNAPSE; SYNAPTIC TRANSMISSION; 129 MOUSE; ANIMAL; BASOLATERAL AMYGDALA; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; DRUG THERAPY; ELECTRIC SHOCK; MENTAL STRESS; METABOLISM; NERVE TRACT; PATHOPHYSIOLOGY; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE; VISION;

ANIMALS; AVOIDANCE LEARNING; BASOLATERAL NUCLEAR COMPLEX; DISEASE MODELS, ANIMAL; ELECTROSHOCK; FEAR; GLUTAMIC ACID; KETAMINE; MALE; MICE, 129 STRAIN; MICE, INBRED C57BL; NEURAL PATHWAYS; PREFRONTAL CORTEX; PSYCHOTROPIC DRUGS; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; STRESS, PSYCHOLOGICAL; SYNAPSES; SYNAPTIC TRANSMISSION; TISSUE CULTURE TECHNIQUES; VISUAL PERCEPTION;

EID: 84941318141     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.100     Document Type: Article

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