Uncoupling of dopaminergic and subthalamic stimulation: Life-threatening DBS withdrawal syndrome

Movement Disorders

Volumn 30, Issue 10, 2015, Pages 1407-1413

  Reuter, Sigrid ^a   Deuschl, Günther ^a   Falk, Daniela ^a   Mehdorn, Maximilian ^a   Witt, Karsten ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Deep brain stimulation; Dopamine; Infection; Parkinson's disease; Subthalamic nucleus

Indexed keywords

AMANTADINE; APOMORPHINE; CARBIDOPA PLUS LEVODOPA; CEFOTAXIME; CEFPODOXIME; CEFTRIAXONE; CLINDAMYCIN; CLOZAPINE; DOPAMINE; GENTAMICIN; LEVODOPA; MEROPENEM; METRONIDAZOLE; MOXIFLOXACIN; RIFAMPICIN; VANCOMYCIN; DOPAMINE RECEPTOR STIMULATING AGENT;

ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BRAIN DEPTH STIMULATION; CASE REPORT; CONTINUOUS INFUSION; DEATH; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSARTHRIA; DYSPHAGIA; FEMALE; HALLUCINATION; HUMAN; INFECTION; MALE; MIDDLE AGED; PARKINSON DISEASE; PNEUMONIA; PRIORITY JOURNAL; STAPHYLOCOCCUS INFECTION; SUBTHALAMIC NUCLEUS; UNIFIED PARKINSON DISEASE RATING SCALE; URINARY TRACT INFECTION; WITHDRAWAL SYNDROME; ADVERSE EFFECTS; DEVICE REMOVAL; DEVICES;

ADULT; AGED; DEEP BRAIN STIMULATION; DEVICE REMOVAL; DOPAMINE AGENTS; FEMALE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; SUBTHALAMIC NUCLEUS;

EID: 84941187256     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.26324     Document Type: Article

References (22)

1. Deuschl G, Agid Y. Subthalamic neurostimulation for Parkinson's disease with early fluctuations: balancing the risks and benefits. Lancet Neurol 2013;12:1025-1034.
2. Blomstedt P, Bjartmarz H. Intracerebral infections as a complication of deep brain stimulation. Stereotact Funct Neurosurg 2012;90:92-96.
3. Bhatia R, Dalton A, Richards M, Hopkins C, Aziz T, Nandi D. The incidence of deep brain stimulator hardware infection: the effect of change in antibiotic prophylaxis regimen and review of the literature. Br J Neurosurg 2011;25:625-631.
4. Vergani F, Landi A, Pirillo D, Cilia R, Antonini A, Sganzerla EP. Surgical, medical, and hardware adverse events in a series of 141 patients undergoing subthalamic deep brain stimulation for Parkinson disease. World Neurosurg 2010;73:338-344.
5. Sixel-Doring F, Trenkwalder C, Kappus C, Hellwig D. Skin complications in deep brain stimulation for Parkinson's disease: frequency, time course, and risk factors. Acta Neurochir (Wien) 2010;152:195-200.
6. Hamani C, Lozano AM. Hardware-related complications of deep brain stimulation: a review of the published literature. Stereotact Funct Neurosurg 2006;84:248-251.
7. Fenoy AJ, Simpson RK. Management of device-related wound complications in deep brain stimulation surgery. J Neurosurg 2012;116:1324-1332.
8. Pepper J, Zrinzo L, Mirza B, Foltynie T, Limousin P, Hariz M. The risk of hardware infection in deep brain stimulation surgery is greater at impulse generator replacement than at the primary procedure. Stereotact Funct Neurosurg 2013;91:56-65.
9. Onofrj M, Bonanni L, Cossu G, Manca D, Stocchi F, Thomas A. Emergencies in parkinsonism: akinetic crisis, life-threatening dyskinesias, and polyneuropathy during L-dopa gel treatment. Parkinsonism Relat Disord 2009;15(Suppl 3):S233-236.
10. Schuepbach WM, Rau J, Knudsen K, et al. Neurostimulation for Parkinson's disease with early motor complications. N Engl J Med 2013;368:610-622.
11. Fily F, Haegelen C, Tattevin P, et al. Deep brain stimulation hardware-related infections: a report of 12 cases and review of the literature. Clin Infect Dis 2011;52:1020-1023.
12. Piacentino M, Pilleri M, Bartolomei L. Hardware-related infections after deep brain stimulation surgery: review of incidence, severity and management in 212 single-center procedures in the first year after implantation. Acta Neurochir 2011;153:2337-2341.
13. Morishita T, Foote KD, Burdick AP, et al. Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies. Parkinsonism Relat Disord 2010;16:153-162.
14. Neuneier J, Barbe MT, Dohmen C, et al. Malignant deep brain stimulation-withdrawal syndrome in a patient with Parkinson's disease. Mov Disord 2013;28:1640-1641.
15. Braak H, Del Tredici K. Cortico-basal ganglia-cortical circuitry in Parkinson's disease reconsidered. Exp Neurol 2008;212:226-229.
16. Braak H, Del Tredici K. [A new look at the corticostriatal-thalamocortical circuit in sporadic Parkinson's disease]. Nervenarzt 2008;79:1440-1445.
17. Braak H, Del Tredici K. Invited article: nervous system pathology in sporadic Parkinson disease. Neurology 2008;70:1916-1925.
18. Day M, Wang Z, Ding J, et al. Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nat Neurosci 2006;9:251-259.
19. Stephens B, Mueller AJ, Shering AF, et al. Evidence of a breakdown of corticostriatal connections in Parkinson's disease. Neuroscience 2005;132:741-754.
20. Braak H, Sastre M, Del Tredici K. Development of alpha-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson's disease. Acta Neuropathol 2007;114:231-241.
21. Kang G, Lowery MM. Effects of antidromic and orthodromic activation of STN afferent axons during DBS in Parkinson's disease: a simulation study. Front Comput Neurosci 2014;8:32.
22. Li S, Arbuthnott GW, Jutras MJ, Goldberg JA, Jaeger D. Resonant antidromic cortical circuit activation as a consequence of high-frequency subthalamic deep-brain stimulation. J Neurophysiol 2007;98:3525-3537.