메뉴 건너뛰기




Volumn 173, Issue 2, 2015, Pages 498-509

Risk of skin ulcerations associated with oral nicorandil therapy: A population-based study

Author keywords

[No Author keywords available]

Indexed keywords

NICORANDIL; VASODILATOR AGENT;

EID: 84941170275     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/bjd.13884     Document Type: Article
Times cited : (12)

References (46)
  • 1
    • 84868194182 scopus 로고    scopus 로고
    • Nicorandil: Do the dermatological and gastrointestinal risks outweigh the benefits?
    • Smith VM, Lyon CC,. Nicorandil: do the dermatological and gastrointestinal risks outweigh the benefits? Br J Dermatol 2012; 167: 1048-52.
    • (2012) Br J Dermatol , vol.167 , pp. 1048-1052
    • Smith, V.M.1    Lyon, C.C.2
  • 2
    • 12944255781 scopus 로고    scopus 로고
    • Effects of intravenous nicorandil on coronary circulation in humans: Plasma concentration and action mechanism
    • Nakae I, Matsumoto T, Horie H, et al,. Effects of intravenous nicorandil on coronary circulation in humans: plasma concentration and action mechanism. J Cardiovasc Pharmacol 2000; 35: 919-25.
    • (2000) J Cardiovasc Pharmacol , vol.35 , pp. 919-925
    • Nakae, I.1    Matsumoto, T.2    Horie, H.3
  • 3
    • 0023485276 scopus 로고
    • Similarity and dissimilarity in the mode and mechanism of action between nicorandil and classical nitrates: An overview
    • Taira N,. Similarity and dissimilarity in the mode and mechanism of action between nicorandil and classical nitrates: an overview. J Cardiovasc Pharmacol 1987; 10 (Suppl. 8): S1-9.
    • (1987) J Cardiovasc Pharmacol , vol.10 , pp. S1-S9
    • Taira, N.1
  • 4
    • 79959715387 scopus 로고    scopus 로고
    • Use of nicorandil in cardiovascular disease and its optimization
    • Horinaka S,. Use of nicorandil in cardiovascular disease and its optimization. Drugs 2011; 71: 1105-19.
    • (2011) Drugs , vol.71 , pp. 1105-1119
    • Horinaka, S.1
  • 5
    • 0024995674 scopus 로고
    • Comparison of nicorandil and atenolol in stable angina pectoris
    • Hughes LO, Rose EL, Lahiri A, et al,. Comparison of nicorandil and atenolol in stable angina pectoris. Am J Cardiol 1990; 66: 679-82.
    • (1990) Am J Cardiol , vol.66 , pp. 679-682
    • Hughes, L.O.1    Rose, E.L.2    Lahiri, A.3
  • 6
    • 0027471593 scopus 로고
    • A double-blind comparison of nicorandil and metoprolol in stable effort angina pectoris
    • Di Somma S, Liguori V, Petitto M, et al,. A double-blind comparison of nicorandil and metoprolol in stable effort angina pectoris. Cardiovasc Drugs Ther 1993; 7: 119-23.
    • (1993) Cardiovasc Drugs Ther , vol.7 , pp. 119-123
    • Di Somma, S.1    Liguori, V.2    Petitto, M.3
  • 7
    • 0026671883 scopus 로고
    • Efficacy of nicorandil versus propranolol in mild stable angina pectoris of effort: A long-term, double-blind, randomized study
    • Meeter K, Kelder JC, Tijssen JG, et al,. Efficacy of nicorandil versus propranolol in mild stable angina pectoris of effort: a long-term, double-blind, randomized study. J Cardiovasc Pharmacol 1992; 20 (Suppl. 3): S59-66.
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. S59-S66
    • Meeter, K.1    Kelder, J.C.2    Tijssen, J.G.3
  • 8
    • 0026214338 scopus 로고
    • A new anti-ischemic drug for the treatment of stable effort angina pectoris: Nicorandil. Comparison with placebo and isosorbide-5-mononitrate
    • (in Italian)
    • Lai C, Onnis E, Solinas R, et al,. [A new anti-ischemic drug for the treatment of stable effort angina pectoris: nicorandil. Comparison with placebo and isosorbide-5-mononitrate]. Cardiologia 1991; 36: 703-11 (in Italian).
    • (1991) Cardiologia , vol.36 , pp. 703-711
    • Lai, C.1    Onnis, E.2    Solinas, R.3
  • 9
    • 34249706865 scopus 로고    scopus 로고
    • Double-blind, multicenter, active-controlled, randomized clinical trial to assess the safety and efficacy of orally administered nicorandil in patients with stable angina pectoris in China
    • Zhu WL, Shan YD, Guo JX, et al,. Double-blind, multicenter, active-controlled, randomized clinical trial to assess the safety and efficacy of orally administered nicorandil in patients with stable angina pectoris in China. Circ J 2007; 71: 826-33.
    • (2007) Circ J , vol.71 , pp. 826-833
    • Zhu, W.L.1    Shan, Y.D.2    Guo, J.X.3
  • 10
    • 0026745121 scopus 로고
    • Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: Results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients
    • Doring G,. Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients. J Cardiovasc Pharmacol 1992; 20 (Suppl. 3): S74-81.
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. S74-S81
    • Doring, G.1
  • 11
    • 0026526233 scopus 로고
    • A multicenter comparison of nicorandil and diltiazem on serum lipid, apolipoprotein, and lipoprotein levels in patients with ischemic heart disease
    • Sasaki J, Saeki Y, Kawasaki K, et al,. A multicenter comparison of nicorandil and diltiazem on serum lipid, apolipoprotein, and lipoprotein levels in patients with ischemic heart disease. Cardiovasc Drugs Ther 1992; 6: 471-4.
    • (1992) Cardiovasc Drugs Ther , vol.6 , pp. 471-474
    • Sasaki, J.1    Saeki, Y.2    Kawasaki, K.3
  • 12
    • 0027244102 scopus 로고
    • A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris
    • Guermonprez JL, Blin P, Peterlongo F,. A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris. Eur Heart J 1993; 14 (Suppl. B): 30-4.
    • (1993) Eur Heart J , vol.14 , pp. 30-34
    • Guermonprez, J.L.1    Blin, P.2    Peterlongo, F.3
  • 13
    • 0026739852 scopus 로고
    • Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: A double-blind, randomized, multicenter study
    • Ulvenstam G, Diderholm E, Frithz G, et al,. Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study. J Cardiovasc Pharmacol 1992; 20 (Suppl. 3): S67-73.
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. S67-S73
    • Ulvenstam, G.1    Diderholm, E.2    Frithz, G.3
  • 14
    • 0033405112 scopus 로고    scopus 로고
    • Comparison of the antiischaemic and antianginal effects of nicorandil and amlodipine in patients with symptomatic stable angina pectoris: The SWAN study
    • Swan Study Group
    • Swan Study Group. Comparison of the antiischaemic and antianginal effects of nicorandil and amlodipine in patients with symptomatic stable angina pectoris: the SWAN study. J Clin Basic Cardiol 1999; 2: 213-17.
    • (1999) J Clin Basic Cardiol , vol.2 , pp. 213-217
  • 15
    • 0030981241 scopus 로고    scopus 로고
    • [Giant buccal aphthosis caused by nicorandil]
    • (in French)
    • Boulinguez S, Bedane C, Bouyssou-Gauthier ML, et al,. [Giant buccal aphthosis caused by nicorandil]. Presse Med 1997; 26: 558 (in French).
    • (1997) Presse Med , vol.26 , pp. 558
    • Boulinguez, S.1    Bedane, C.2    Bouyssou-Gauthier, M.L.3
  • 16
    • 0031051232 scopus 로고    scopus 로고
    • Major aphthous stomatitis induced by nicorandil
    • Reichert S, Antunes A, Trechot P, et al,. Major aphthous stomatitis induced by nicorandil. Eur J Dermatol 1997; 7: 132-3.
    • (1997) Eur J Dermatol , vol.7 , pp. 132-133
    • Reichert, S.1    Antunes, A.2    Trechot, P.3
  • 17
    • 84922008041 scopus 로고    scopus 로고
    • Ulceration of the nasal dorsum: A rare cause?
    • Salim F, Joshi A, Hopkins C,. Ulceration of the nasal dorsum: a rare cause? J Laryngol Otol 2014; 128: 289-91.
    • (2014) J Laryngol Otol , vol.128 , pp. 289-291
    • Salim, F.1    Joshi, A.2    Hopkins, C.3
  • 18
    • 84862221387 scopus 로고    scopus 로고
    • Nicorandil as a cause of perineal ulceration
    • Robinson A, Baker P, Stevenson H,. Nicorandil as a cause of perineal ulceration. Ulster Med J 2012; 81: 97.
    • (2012) Ulster Med J , vol.81 , pp. 97
    • Robinson, A.1    Baker, P.2    Stevenson, H.3
  • 19
    • 84873724254 scopus 로고    scopus 로고
    • Leg ulcers associated with nicorandil are possibly underdiagnosed
    • Shams K, Mukkanna KS, Loney MD, et al,. Leg ulcers associated with nicorandil are possibly underdiagnosed. Clin Exp Dermatol 2013; 38: 193-4.
    • (2013) Clin Exp Dermatol , vol.38 , pp. 193-194
    • Shams, K.1    Mukkanna, K.S.2    Loney, M.D.3
  • 20
    • 79955955581 scopus 로고    scopus 로고
    • Nicorandil-induced leg ulceration without mucosal involvement
    • Mikeljevic J, Highet AS,. Nicorandil-induced leg ulceration without mucosal involvement. Clin Exp Dermatol 2011; 36: 372-3.
    • (2011) Clin Exp Dermatol , vol.36 , pp. 372-373
    • Mikeljevic, J.1    Highet, A.S.2
  • 21
    • 78651094679 scopus 로고    scopus 로고
    • Nicorandil-induced penile ulcerations: A case series
    • Yap T, Philippou P, Perry M, et al,. Nicorandil-induced penile ulcerations: a case series. BJU Int 2011; 107: 268-71.
    • (2011) BJU Int , vol.107 , pp. 268-271
    • Yap, T.1    Philippou, P.2    Perry, M.3
  • 23
    • 68849102923 scopus 로고    scopus 로고
    • Vulvovaginal ulceration during prolonged treatment with nicorandil
    • Chan SK, Harris MD, Baldwin PJ, et al,. Vulvovaginal ulceration during prolonged treatment with nicorandil. BJOG 2009; 116: 1403-5.
    • (2009) BJOG , vol.116 , pp. 1403-1405
    • Chan, S.K.1    Harris, M.D.2    Baldwin, P.J.3
  • 24
    • 68849093053 scopus 로고    scopus 로고
    • Vulval ulceration induced by the potassium-channel activator Nicorandil: A case series of five patients
    • Fraser SJ, Pinion SB, Adamson B, et al,. Vulval ulceration induced by the potassium-channel activator Nicorandil: a case series of five patients. BJOG 2009; 116: 1400-2.
    • (2009) BJOG , vol.116 , pp. 1400-1402
    • Fraser, S.J.1    Pinion, S.B.2    Adamson, B.3
  • 25
    • 65249174030 scopus 로고    scopus 로고
    • Nicorandil-induced foreskin ulceration
    • Bhatti I, Cohen SN, Bleiker T, et al,. Nicorandil-induced foreskin ulceration. Colorectal Dis 2009; 11: 424-5.
    • (2009) Colorectal Dis , vol.11 , pp. 424-425
    • Bhatti, I.1    Cohen, S.N.2    Bleiker, T.3
  • 26
    • 79960939137 scopus 로고    scopus 로고
    • Nicorandil associated colonic ulceration: Case series of an increasingly recognized complication
    • Lee BC, Allen PB, Caddy GR, et al,. Nicorandil associated colonic ulceration: case series of an increasingly recognized complication. Dig Dis Sci 2011; 56: 2404-8.
    • (2011) Dig Dis Sci , vol.56 , pp. 2404-2408
    • Lee, B.C.1    Allen, P.B.2    Caddy, G.R.3
  • 27
    • 79960393953 scopus 로고    scopus 로고
    • Rectal ulceration caused by the anti-anginal nicorandil: Case report of a preventable complication
    • Malde S, Wilson A,. Rectal ulceration caused by the anti-anginal nicorandil: case report of a preventable complication. Patient Saf Surg 2010; 4: 10.
    • (2010) Patient Saf Surg , vol.4 , pp. 10
    • Malde, S.1    Wilson, A.2
  • 28
    • 33750930719 scopus 로고    scopus 로고
    • Nicorandil-associated para-stomal ulceration: Case series
    • Abdelrazeq AS, Owen C, Smith L, et al,. Nicorandil-associated para-stomal ulceration: Case series. Eur J Gastroenterol Hepatol 2006; 18: 1293-5.
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 1293-1295
    • Abdelrazeq, A.S.1    Owen, C.2    Smith, L.3
  • 29
    • 33748563102 scopus 로고    scopus 로고
    • Anal ulceration associated with Nicorandil: Case series and review of the literature
    • Toquero L, Briggs CD, Bassuini MM, et al,. Anal ulceration associated with Nicorandil: case series and review of the literature. Colorectal Dis 2006; 8: 717-20.
    • (2006) Colorectal Dis , vol.8 , pp. 717-720
    • Toquero, L.1    Briggs, C.D.2    Bassuini, M.M.3
  • 30
    • 33645968149 scopus 로고    scopus 로고
    • Nicorandil may be associated with gastrointestinal ulceration
    • Egred M, Andron M, Morrison WL,. Nicorandil may be associated with gastrointestinal ulceration. BMJ 2006; 332: 889.
    • (2006) BMJ , vol.332 , pp. 889
    • Egred, M.1    Andron, M.2    Morrison, W.L.3
  • 31
    • 84901356679 scopus 로고    scopus 로고
    • Corneal perforation: Another side effect of nicorandil
    • Campolmi N, Guy C, Cinotti E, et al,. Corneal perforation: another side effect of nicorandil. Cutan Ocul Toxicol 2014; 33: 96-8.
    • (2014) Cutan Ocul Toxicol , vol.33 , pp. 96-98
    • Campolmi, N.1    Guy, C.2    Cinotti, E.3
  • 32
    • 84901376793 scopus 로고    scopus 로고
    • Conjunctival and corneal ulceration associated with nicorandil
    • Fraunfelder FW, Fraunfelder FT,. Conjunctival and corneal ulceration associated with nicorandil. Cutan Ocul Toxicol 2014; 33: 120-1.
    • (2014) Cutan Ocul Toxicol , vol.33 , pp. 120-121
    • Fraunfelder, F.W.1    Fraunfelder, F.T.2
  • 33
    • 84900432271 scopus 로고    scopus 로고
    • A case of nicorandil-induced unilateral corneal ulceration
    • Trechot F, Batta B, Petitpain N, et al,. A case of nicorandil-induced unilateral corneal ulceration. Int Wound J 2014; 11: 238-9.
    • (2014) Int Wound J , vol.11 , pp. 238-239
    • Trechot, F.1    Batta, B.2    Petitpain, N.3
  • 35
    • 84859760984 scopus 로고    scopus 로고
    • Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus
    • Chang CH, Lin JW, Wu LC, et al,. Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus. Hepatology 2012; 55: 1462-72.
    • (2012) Hepatology , vol.55 , pp. 1462-1472
    • Chang, C.H.1    Lin, J.W.2    Wu, L.C.3
  • 36
    • 84879124959 scopus 로고    scopus 로고
    • Association between traditional systemic antipsoriatic drugs and tuberculosis risk in patients with psoriasis with or without psoriatic arthritis: Results of a nationwide cohort study from Taiwan
    • Chen YJ, Wu CY, Shen JL, et al,. Association between traditional systemic antipsoriatic drugs and tuberculosis risk in patients with psoriasis with or without psoriatic arthritis: results of a nationwide cohort study from Taiwan. J Am Acad Dermatol 2013; 69: 25-33.
    • (2013) J Am Acad Dermatol , vol.69 , pp. 25-33
    • Chen, Y.J.1    Wu, C.Y.2    Shen, J.L.3
  • 37
    • 84871099014 scopus 로고    scopus 로고
    • Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
    • Murray CJ, Vos T, Lozano R, et al,. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2197-223.
    • (2012) Lancet , vol.380 , pp. 2197-2223
    • Murray, C.J.1    Vos, T.2    Lozano, R.3
  • 38
    • 0142157169 scopus 로고    scopus 로고
    • Evaluating medication effects outside of clinical trials: New-user designs
    • Ray WA,. Evaluating medication effects outside of clinical trials: new-user designs. Am J Epidemiol 2003; 158: 915-20.
    • (2003) Am J Epidemiol , vol.158 , pp. 915-920
    • Ray, W.A.1
  • 39
    • 33747032013 scopus 로고    scopus 로고
    • The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology
    • Bickers DR, Lim HW, Margolis D, et al,. The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. J Am Acad Dermatol 2006; 55: 490-500.
    • (2006) J Am Acad Dermatol , vol.55 , pp. 490-500
    • Bickers, D.R.1    Lim, H.W.2    Margolis, D.3
  • 40
    • 0034913876 scopus 로고    scopus 로고
    • Quality of care for hospitalized Medicare patients at risk for pressure ulcers
    • Lyder CH, Preston J, Grady JN, et al,. Quality of care for hospitalized Medicare patients at risk for pressure ulcers. Arch Intern Med 2001; 161: 1549-54.
    • (2001) Arch Intern Med , vol.161 , pp. 1549-1554
    • Lyder, C.H.1    Preston, J.2    Grady, J.N.3
  • 41
    • 3142619572 scopus 로고    scopus 로고
    • Direct health care costs of 4 common skin ulcers in New Mexico Medicaid fee-for-service patients
    • Kumar RN, Gupchup GV, Dodd MA, et al,. Direct health care costs of 4 common skin ulcers in New Mexico Medicaid fee-for-service patients. Adv Skin Wound Care 2004; 17: 143-9.
    • (2004) Adv Skin Wound Care , vol.17 , pp. 143-149
    • Kumar, R.N.1    Gupchup, G.V.2    Dodd, M.A.3
  • 42
    • 84941739932 scopus 로고    scopus 로고
    • Role of nicotinic acid and nicotinamide in nicorandil-induced ulcerations: From hypothesis to demonstration
    • Trechot P, Jouzeau JY, Brouillard C, et al,. Role of nicotinic acid and nicotinamide in nicorandil-induced ulcerations: from hypothesis to demonstration. Int Wound J 2013; doi: 10.1111/iwj.12147.
    • (2013) Int Wound J
    • Trechot, P.1    Jouzeau, J.Y.2    Brouillard, C.3
  • 43
    • 84941168989 scopus 로고    scopus 로고
    • Medicines and Healthcare products Regulatory Agency. Available at: (last accessed 30 April 2015)
    • Medicines and Healthcare products Regulatory Agency. Nicorandil 10 mg and 20 mg tablets. Available at: http://www.mhra.gov.uk/home/groups/par/documents/websiteresources/con126185.pdf (last accessed 30 April 2015).
    • Nicorandil 10 Mg and 20 Mg Tablets
  • 44
    • 32844475096 scopus 로고    scopus 로고
    • Venous and arterial leg ulcers
    • Grey JE, Harding KG, Enoch S,. Venous and arterial leg ulcers. BMJ 2006; 332: 347-50.
    • (2006) BMJ , vol.332 , pp. 347-350
    • Grey, J.E.1    Harding, K.G.2    Enoch, S.3
  • 45
    • 0013901427 scopus 로고
    • Hypertensive ischemic ulcer. A review of 40 cases
    • Schnier BR, Sheps SG, Juergens JL,. Hypertensive ischemic ulcer. A review of 40 cases. Am J Cardiol 1966; 17: 560-5.
    • (1966) Am J Cardiol , vol.17 , pp. 560-565
    • Schnier, B.R.1    Sheps, S.G.2    Juergens, J.L.3
  • 46
    • 0027968619 scopus 로고
    • Evidence of the depletion of susceptibles effect in non-experimental pharmacoepidemiologic research
    • Yola M, Lucien A,. Evidence of the depletion of susceptibles effect in non-experimental pharmacoepidemiologic research. J Clin Epidemiol 1994; 47: 731-7.
    • (1994) J Clin Epidemiol , vol.47 , pp. 731-737
    • Yola, M.1    Lucien, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.