Lower Coated-Platelet Levels Are Associated with Increased Mortality after Spontaneous Intracerebral Hemorrhage

Stroke

Volumn 46, Issue 7, 2015, Pages 1819-1825

  Prodan, Calin I ^a,d   Stoner, Julie A ^b   Dale, George L ^c  

^a Departments of Neurology   (United States)

^b Departments of Biostatistics and Epidemiology   (United States)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

hemorrhage; platelets; stroke; thrombosis

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN HEMORRHAGE; COATED PLATELET; CONTROLLED STUDY; DEATH; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; THROMBOCYTE; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; TREND STUDY; BLOOD; BLOOD CLOTTING PARAMETERS; CEREBRAL HEMORRHAGE; METABOLISM; MIDDLE AGED; RISK FACTOR; TRENDS; VERY ELDERLY;

COLLAGEN; THROMBIN;

ADULT; AGED; AGED, 80 AND OVER; BLOOD PLATELETS; CEREBRAL HEMORRHAGE; COLLAGEN; FEMALE; HUMANS; MALE; MIDDLE AGED; MORTALITY; PLATELET FUNCTION TESTS; PROSPECTIVE STUDIES; RISK FACTORS; THROMBIN;

EID: 84941103497     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.115.009068     Document Type: Article

References (30)

1. Dale GL, Friese P, Batar P, Hamilton SF, Reed GL, Jackson KW, et al. Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface. Nature. 2002;415:175-179. doi:10.1038/415175a.
2. Dale GL. Coated-platelets: an emerging component of the procoagulant response. J Thromb Haemost. 2005;3:2185-2192. doi:10.1111/j.1538-7836.2005.01274.x.
3. Szasz R, Dale GL. COAT platelets. Curr Opin Hematol. 2003;10:351-355.
4. Dale GL, Remenyi G, Friese P. Quantitation of microparticles released from coated-platelets. J Thromb Haemost. 2005;3:2081-2088. doi:10.1111/j.1538-7836.2005.01528.x.
5. Remenyi G, Szasz R, Friese P, Dale GL. Role of mitochondrial permeability transition pore in coated-platelet formation. Arterioscler Thromb Vasc Biol. 2005;25:467-471. doi: 10.1161/01.ATV.0000152726.49229. bf.
6. Alberio L, Safa O, Clemetson KJ, Esmon CT, Dale GL. Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin. Blood. 2000;95:1694-1702.
7. Prodan CI, Joseph PM, Vincent AS, Dale GL. Coated-platelet levels are influenced by smoking, aspirin, and selective serotonin reuptake inhibitors. J Thromb Haemost. 2007;5:2149-2151. doi:10.1111/j.1538-7836.2007.02691.x.
8. Prodan CI, Vincent AS, Padmanabhan R, Dale GL. Coated-platelet levels are low in patients with spontaneous intracerebral hemorrhage. Stroke. 2009;40:2578-2580. doi: 10.1161/STROKEAHA.109.549014.
9. Prodan CI, Vincent AS, Dale GL. coated platelet levels correlate with bleed volume in patients with spontaneous intracerebral hemorrhage. Stroke. 2010;41:1301-1303. doi: 10.1161/STROKEAHA.110.581447.
10. Morgenstern LB, Hemphill JC 3rd, Anderson C, Becker K, Broderick JP, Connolly ES Jr, et al; American Heart Association Stroke Council and Council on Cardiovascular Nursing. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2010;41:2108-2129. doi: 10.1161/STR.0b013e3181ec611b.
11. Charania R, Smith J, Vesely SK, Dale GL, Holter J. Quantitation of coated platelet potential during collection, storage, and transfusion of apheresis platelets. Transfusion. 2011;51:2690-2694. doi:10.1111/j.1537-2995.2011.03179.x.
12. Prodan CI, Szasz R, Vincent AS, Ross ED, Dale GL. Coated-platelets retain amyloid precursor protein on their surface. Platelets. 2006;17:56-doi: 10.1080/09537100500181913.
13. Norgard NB, Saya S, Hann CL, Hennebry TA, Schechter E, Dale GL. Clopidogrel attenuates coated-platelet production in patients undergoing elective coronary catheterization. J Cardiovasc Pharmacol. 2008;52:536-539. doi: 10.1097/FJC.0b013e3181907390.
14. Jenkins AJ, Gosmanova AK, Lyons TJ, May KD, Dashti A, Baker MZ, et al. Coated-platelet levels in patients with Type 1 and with Type 2 diabetes mellitus. Diabetes Res Clin Pract. 2008;81:e8-10. doi: 10.1016/j. diabres.2008.04.004.
15. Valaydon ZS, Lee P, Dale GL, Januszewski AS, Rowley KG, Nandurkar H, et al. Increased coated-platelet levels in chronic haemodialysis patients. Nephrology (Carlton). 2009;14:148-154. doi:10.1111/j.1440-1797.2008.01026.x.
16. Prodan CI, Joseph PM, Vincent AS, Dale GL. Coated-platelets in ischemic stroke: differences between lacunar and cortical stroke. J Thromb Haemost. 2008;6:609-614. doi: 10.1111/j.1538-7836.2008.02890.x.
17. Prodan CI, Vincent AS, Dale GL. Higher coated-platelet levels are associated with chronic hypertension in patients with transient ischemic attack. Platelets. 2013;24:316-319. doi: 10.3109/09537104.2012.696747.
18. Prodan CI, Vincent AS, Dale GL. Coated-platelet levels are elevated in patients with transient ischemic attack. Transl Res. 2011;158:71-75. doi:10.1016/j.trsl.2011.02.010.
19. Prodan CI, Vincent AS, Dale GL. Coated-platelet levels are persistently elevated in patients with mild traumatic brain injury. J Head Trauma Rehabil. 2014;29:522-526. doi: 10.1097/HTR.0000000000000010.
20. Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, et al. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27:1304-1305.
21. Prodan CI, Stoner JA, Cowan LD, Dale GL. Lower coated-platelet levels are associated with early hemorrhagic transformation in patients with non-lacunar brain infarction. J Thromb Haemost. 2010;8:1185-1190. doi: 10.1111/j.1538-7836.2010.03851.x.
22. Maldonado G, Greenland S. Simulation study of confounder-selection strategies. Am J Epidemiol. 1993;138:923-936.
23. PASS 2014. NCSS, LLC [computer program]. Kaysville, Utah. 2014.
24. Prodan CI, Vincent AS, Kirkpatrick AC, Hoover SL, Dale GL. Higher levels of coated-platelets are observed in patients with subarachnoid hemorrhage but lower levels are associated with increased mortality at 30 days. J Neurol Sci. 2013;334:126-129. doi: 10.1016/j.jns.2013.08.008.
25. Brooks MB, Catalfamo JL, Friese P, Dale GL. Scott syndrome dogs have impaired coated-platelet formation and calcein-release but normal mitochondrial depolarization. J Thromb Haemost. 2007;5:1972-1974. doi:10.1111/j.1538-7836.2007.02683.x.
26. Daskalakis M, Colucci G, Keller P, Rochat S, Silzle T, Biasiutti FD, et al. Decreased generation of procoagulant platelets detected by flow cytometric analysis in patients with bleeding diathesis. Cytometry B Clin Cytom. 2014;86:397-409. doi: 10.1002/cyto.b.21157.
27. Saxena K, Pethe K, Dale GL. Coated-platelet levels may explain some variability in clinical phenotypes observed with severe hemophilia. J Thromb Haemost. 2010;8:1140-1142. doi: 10.1111/j.1538-7836.2010.03828.x.
28. Brouwers HB, Chang Y, Falcone GJ, Cai X, Ayres AM, Battey TW, et al. Predicting hematoma expansion after primary intracerebral hemorrhage. JAMA Neurol. 2014;71:158-164. doi: 10.1001/jamaneurol.2013.5433.
29. Pecci A, Balduini CL. Desmopressin and super platelets. Blood. 2014;123:1779-1780. doi: 10.1182/blood-2014-01-551242.
30. Colucci G, Stutz M, Rochat S, Conte T, Pavicic M, Reusser M, et al. The effect of desmopressin on platelet function: a selective enhancement of procoagulant COAT platelets in patients with primary platelet function defects. Blood. 2014;123:1905-1916. doi: 10.1182/blood-2013-04-497123.