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Volumn 243, Issue 1, 2015, Pages 86-92

Mediation analysis of the relationship between sex, cardiovascular risk factors and mortality from coronary heart disease: Findings from the population-based VHM&PP cohort

Author keywords

Cardiovascular disease risk factors; Coronary heart disease; Epidemiology; Gender; Mediation analysis; Sex

Indexed keywords

CHOLESTEROL; GLUCOSE; GLUCOSE BLOOD LEVEL;

EID: 84941067477     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2015.08.048     Document Type: Article
Times cited : (16)

References (48)
  • 1
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
    • Lozano R., Naghavi M., Foreman K., Lim S., Shibuya K., Aboyans V., et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012, 380:2095-2128. 10.1016/S0140-6736(12)61728-0.
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3    Lim, S.4    Shibuya, K.5    Aboyans, V.6
  • 2
    • 0022656719 scopus 로고
    • Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population
    • Lerner D.J., Kannel W.B. Patterns of coronary heart disease morbidity and mortality in the sexes: a 26-year follow-up of the Framingham population. Am. Heart J. 1986, 111:383-390. 10.1016/0002-8703(86)90155-9.
    • (1986) Am. Heart J. , vol.111 , pp. 383-390
    • Lerner, D.J.1    Kannel, W.B.2
  • 3
    • 31644443751 scopus 로고    scopus 로고
    • Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies
    • Shaw L.J., Bairey Merz C.N., Pepine C.J., Reis S.E., Bittner V., Kelsey S.F., et al. Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies. J. Am. Coll. Cardiol. 2006, 47:S4-S20. 10.1016/j.jacc.2005.01.072.
    • (2006) J. Am. Coll. Cardiol. , vol.47 , pp. S4-S20
    • Shaw, L.J.1    Bairey Merz, C.N.2    Pepine, C.J.3    Reis, S.E.4    Bittner, V.5    Kelsey, S.F.6
  • 4
    • 84912139288 scopus 로고    scopus 로고
    • Cardiovascular disease in Europe 2014: epidemiological update
    • Nichols M., Townsend N., Scarborough P., Rayner M. Cardiovascular disease in Europe 2014: epidemiological update. Eur. Heart J. 2014, 35:2950-2959. 10.1093/eurheartj/ehu299.
    • (2014) Eur. Heart J. , vol.35 , pp. 2950-2959
    • Nichols, M.1    Townsend, N.2    Scarborough, P.3    Rayner, M.4
  • 5
    • 1542317532 scopus 로고    scopus 로고
    • Menopause, hormones, and cardiovascular vulnerability in women
    • Kannel W.B., Levy D. Menopause, hormones, and cardiovascular vulnerability in women. Arch. Intern Med. 2004, 164:479-481. 10.1001/archinte.164.5.479.
    • (2004) Arch. Intern Med. , vol.164 , pp. 479-481
    • Kannel, W.B.1    Levy, D.2
  • 6
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw J.E., Anderson G.L., Prentice R.L., LaCroix A.Z., Kooperberg C., Stefanick M.L., et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002, 288:321-333. 10.1001/jama.288.3.321.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3    LaCroix, A.Z.4    Kooperberg, C.5    Stefanick, M.L.6
  • 7
    • 84899954927 scopus 로고    scopus 로고
    • Testosterone and cardiovascular disease
    • Schooling C.M. Testosterone and cardiovascular disease. Curr. Opin. Endocrinol. Diabetes Obes. 2014, 21:202-208. 10.1097/MED.0000000000000065.
    • (2014) Curr. Opin. Endocrinol. Diabetes Obes. , vol.21 , pp. 202-208
    • Schooling, C.M.1
  • 8
    • 41849150370 scopus 로고    scopus 로고
    • Risk factors for myocardial infarction in women and men: insights from the INTERHEART study
    • Anand S.S., Islam S., Rosengren A., Franzosi M.G., Steyn K., Yusufali A.H., et al. Risk factors for myocardial infarction in women and men: insights from the INTERHEART study. Eur. Heart J. 2008, 29:932-940. 10.1093/eurheartj/ehn018.
    • (2008) Eur. Heart J. , vol.29 , pp. 932-940
    • Anand, S.S.1    Islam, S.2    Rosengren, A.3    Franzosi, M.G.4    Steyn, K.5    Yusufali, A.H.6
  • 9
    • 84884415675 scopus 로고    scopus 로고
    • Gender differences and disparities in all-cause and coronary heart disease mortality: epidemiological aspects
    • Barrett-Connor E. Gender differences and disparities in all-cause and coronary heart disease mortality: epidemiological aspects. Best. Pract. Res. Clin. Endocrinol. Metab. 2013, 27:481-500. 10.1016/j.beem.2013.05.013.
    • (2013) Best. Pract. Res. Clin. Endocrinol. Metab. , vol.27 , pp. 481-500
    • Barrett-Connor, E.1
  • 10
    • 80855133582 scopus 로고    scopus 로고
    • Sex/gender differences in cardiovascular disease prevention: what a difference a decade makes
    • Mosca L., Barrett-Connor E., Wenger N.K. Sex/gender differences in cardiovascular disease prevention: what a difference a decade makes. Circulation 2011, 124:2145-2154. 10.1161/CIRCULATIONAHA.110.968792.
    • (2011) Circulation , vol.124 , pp. 2145-2154
    • Mosca, L.1    Barrett-Connor, E.2    Wenger, N.K.3
  • 11
    • 1542360769 scopus 로고    scopus 로고
    • Why Eve is not Adam: prospective follow-up in 149650 women and men of cholesterol and other risk factors related to cardiovascular and all-cause mortality
    • Ulmer H., Kelleher C., Diem G., Concin H. Why Eve is not Adam: prospective follow-up in 149650 women and men of cholesterol and other risk factors related to cardiovascular and all-cause mortality. J. Womens Health (Larchmt) 2004, 13:41-53. 10.1089/154099904322836447.
    • (2004) J. Womens Health (Larchmt) , vol.13 , pp. 41-53
    • Ulmer, H.1    Kelleher, C.2    Diem, G.3    Concin, H.4
  • 12
    • 0024538088 scopus 로고
    • International comparisons of trends in cigarette smoking prevalence
    • Pierce J.P. International comparisons of trends in cigarette smoking prevalence. Am. J. Public Health 1989, 79:152-157. 10.2105/AJPH.79.2.152.
    • (1989) Am. J. Public Health , vol.79 , pp. 152-157
    • Pierce, J.P.1
  • 13
    • 84888244223 scopus 로고    scopus 로고
    • WHO, Geneva, Switzerland, Available from:, (accessed 18.08.2015)
    • World Health Organization WHO Report on the Global Tobacco Epidemic 2013, WHO, Geneva, Switzerland, Available from:, (accessed 18.08.2015). http://www.who.int/tobacco/global_report/2013/en/.
    • (2013) WHO Report on the Global Tobacco Epidemic
  • 14
    • 0038403929 scopus 로고    scopus 로고
    • Preventing heart disease by controlling hypertension: impact of hypertensive subtype, stage, age ,and sex
    • Wong N.D., Thakral G., Franklin S.S., L'Italien G.J.L., Jacobs M.J., Whyte J.L., et al. Preventing heart disease by controlling hypertension: impact of hypertensive subtype, stage, age ,and sex. Am. Heart J. 2003, 145:888-895. 10.1016/S0002-8703(02)00078-9.
    • (2003) Am. Heart J. , vol.145 , pp. 888-895
    • Wong, N.D.1    Thakral, G.2    Franklin, S.S.3    L'Italien, G.J.L.4    Jacobs, M.J.5    Whyte, J.L.6
  • 15
    • 84907597680 scopus 로고    scopus 로고
    • Temporal trends in the population attributable risk for cardiovascular disease: the Atherosclerosis Risk in Communities Study
    • Cheng S., Claggett B., Correia A.W., Shah A.M., Gupta D.K., Skali H., et al. Temporal trends in the population attributable risk for cardiovascular disease: the Atherosclerosis Risk in Communities Study. Circulation 2014, 130:820-828. 10.1161/CIRCULATIONAHA.113.008506.
    • (2014) Circulation , vol.130 , pp. 820-828
    • Cheng, S.1    Claggett, B.2    Correia, A.W.3    Shah, A.M.4    Gupta, D.K.5    Skali, H.6
  • 16
    • 84896134029 scopus 로고    scopus 로고
    • Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants
    • Lu Y., Hajifathalian K., Ezzati M., Woodward M., Rimm E.B., Danaei G. Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants. Lancet 2014, 383:970-983. 10.1016/S0140-6736(13)61836-X.
    • (2014) Lancet , vol.383 , pp. 970-983
    • Lu, Y.1    Hajifathalian, K.2    Ezzati, M.3    Woodward, M.4    Rimm, E.B.5    Danaei, G.6
  • 17
    • 34548628795 scopus 로고    scopus 로고
    • Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000 persons
    • Bogers R.P., Bemelmans W.J.E., Hoogenveen R.T., Boshuizen H.C., Woodward M., Knekt P., et al. Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000 persons. Arch. Intern Med. 2007, 167:1720-1728. 10.1001/archinte.167.16.1720.
    • (2007) Arch. Intern Med. , vol.167 , pp. 1720-1728
    • Bogers, R.P.1    Bemelmans, W.J.E.2    Hoogenveen, R.T.3    Boshuizen, H.C.4    Woodward, M.5    Knekt, P.6
  • 18
    • 84861570849 scopus 로고    scopus 로고
    • Elevation in cardiovascular disease risk in South Asians is mediated by differences in visceral adipose tissue
    • Lear S.A., Chockalingam A., Kohli S., Richardson C.G., Humphries K.H. Elevation in cardiovascular disease risk in South Asians is mediated by differences in visceral adipose tissue. Obesity (Silver Spring) 2012, 20:1293-1300. 10.1038/oby.2011.395.
    • (2012) Obesity (Silver Spring) , vol.20 , pp. 1293-1300
    • Lear, S.A.1    Chockalingam, A.2    Kohli, S.3    Richardson, C.G.4    Humphries, K.H.5
  • 19
    • 0023020183 scopus 로고
    • The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations
    • Baron R.M., Kenny D.A. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J. Pers. Soc. Psychol. 1986, 51:1173-1182. 10.1037/0022-3514.51.6.1173.
    • (1986) J. Pers. Soc. Psychol. , vol.51 , pp. 1173-1182
    • Baron, R.M.1    Kenny, D.A.2
  • 20
    • 80051551986 scopus 로고    scopus 로고
    • Direct and indirect effects in a survival context
    • Lange T., Hansen J.V. Direct and indirect effects in a survival context. Epidemiology 2011, 22:575-581. 10.1097/EDE.0b013e31821c680c.
    • (2011) Epidemiology , vol.22 , pp. 575-581
    • Lange, T.1    Hansen, J.V.2
  • 21
    • 15544376668 scopus 로고    scopus 로고
    • A further critique of the analytic strategy of adjusting for covariates to identify biologic mediation
    • Kaufman J.S., Maclehose R.F., Kaufman S. A further critique of the analytic strategy of adjusting for covariates to identify biologic mediation. Epidemiol. Perspect. Innov. 2004, 1:4. 10.1186/1742-5573-1-4.
    • (2004) Epidemiol. Perspect. Innov. , vol.1 , pp. 4
    • Kaufman, J.S.1    Maclehose, R.F.2    Kaufman, S.3
  • 22
    • 84864428744 scopus 로고    scopus 로고
    • A simple unified approach for estimating natural direct and indirect effects
    • Lange T., Vansteelandt S., Bekaert M. A simple unified approach for estimating natural direct and indirect effects. Am. J. Epidemiol. 2012, 176:190-195. 10.1093/aje/kwr525.
    • (2012) Am. J. Epidemiol. , vol.176 , pp. 190-195
    • Lange, T.1    Vansteelandt, S.2    Bekaert, M.3
  • 23
    • 84893224979 scopus 로고    scopus 로고
    • Assessing natural direct and indirect effects through multiple pathways
    • Lange T., Rasmussen M., Thygesen L.C. Assessing natural direct and indirect effects through multiple pathways. Am. J. Epidemiol. 2014, 179:513-518. 10.1093/aje/kwt270.
    • (2014) Am. J. Epidemiol. , vol.179 , pp. 513-518
    • Lange, T.1    Rasmussen, M.2    Thygesen, L.C.3
  • 24
    • 84879508081 scopus 로고    scopus 로고
    • Education and risk of coronary heart disease: assessment of mediation by behavioral risk factors using the additive hazards model
    • Nordahl H., Rod N.H., Frederiksen B.L., Andersen I., Lange T., Diderichsen F., et al. Education and risk of coronary heart disease: assessment of mediation by behavioral risk factors using the additive hazards model. Eur. J. Epidemiol. 2013, 28:149-157. 10.1007/s10654-012-9745-z.
    • (2013) Eur. J. Epidemiol. , vol.28 , pp. 149-157
    • Nordahl, H.1    Rod, N.H.2    Frederiksen, B.L.3    Andersen, I.4    Lange, T.5    Diderichsen, F.6
  • 25
    • 29244490638 scopus 로고    scopus 로고
    • Record linkage in the Cancer Registry of Tyrol, Austria
    • Oberaigner W., Stühlinger W. Record linkage in the Cancer Registry of Tyrol, Austria. Methods Inf. Med. 2005, 44:626-630.
    • (2005) Methods Inf. Med. , vol.44 , pp. 626-630
    • Oberaigner, W.1    Stühlinger, W.2
  • 26
    • 84866053567 scopus 로고    scopus 로고
    • The slow death of autopsies: a retrospective analysis of the autopsy prevalence rate in Austria from 1990 to 2009
    • Gaensbacher S., Waldhoer T., Berzlanovich A. The slow death of autopsies: a retrospective analysis of the autopsy prevalence rate in Austria from 1990 to 2009. Eur. J. Epidemiol. 2012, 27:577-580. 10.1007/s10654-012-9709-3.
    • (2012) Eur. J. Epidemiol. , vol.27 , pp. 577-580
    • Gaensbacher, S.1    Waldhoer, T.2    Berzlanovich, A.3
  • 27
    • 0037527538 scopus 로고    scopus 로고
    • Long-term tracking of cardiovascular risk factors among men and women in a large population-based health system the Vorarlberg Health Monitoring & Promotion Programme
    • Ulmer H., Kelleher C., Diem G., Concin H. Long-term tracking of cardiovascular risk factors among men and women in a large population-based health system the Vorarlberg Health Monitoring & Promotion Programme. Eur. Heart J. 2003, 24:1004-1013. 10.1016/S0195-668X(03)00170-2.
    • (2003) Eur. Heart J. , vol.24 , pp. 1004-1013
    • Ulmer, H.1    Kelleher, C.2    Diem, G.3    Concin, H.4
  • 29
    • 84862119222 scopus 로고    scopus 로고
    • European guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts)
    • Perk J., De Backer G., Gohlke H., Graham I., Reiner Z., Verschuren M., et al. European guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur. Heart J. 2012, 33:1635-1701. 10.1093/eurheartj/ehs092.
    • (2012) Eur. Heart J. , vol.33 , pp. 1635-1701
    • Perk, J.1    De Backer, G.2    Gohlke, H.3    Graham, I.4    Reiner, Z.5    Verschuren, M.6
  • 32
    • 84863304598 scopus 로고    scopus 로고
    • R Foundation for Statistical Computing, Vienna, Austria, (accessed 18.08.2015)
    • R Core Team R: A Language and Environment for Statistical Computing 2013, R Foundation for Statistical Computing, Vienna, Austria, (accessed 18.08.2015). http://www.R-project.org/.
    • (2013) R: A Language and Environment for Statistical Computing
  • 33
    • 84880795072 scopus 로고    scopus 로고
    • The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis
    • Singh G.M., Danaei G., Farzadfar F., Stevens G.A., Woodward M., Wormser D., et al. The age-specific quantitative effects of metabolic risk factors on cardiovascular diseases and diabetes: a pooled analysis. PLoS One 2013, 8:e65174. 10.1371/journal.pone.0065174.
    • (2013) PLoS One , vol.8 , pp. e65174
    • Singh, G.M.1    Danaei, G.2    Farzadfar, F.3    Stevens, G.A.4    Woodward, M.5    Wormser, D.6
  • 34
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
    • Yusuf S., Hawken S., Ounpuu S., Dans T., Avezum A., Lanas F., et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004, 364:937-952. 10.1016/S0140-6736(04)17018-9.
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3    Dans, T.4    Avezum, A.5    Lanas, F.6
  • 35
    • 23244441835 scopus 로고    scopus 로고
    • Sex hormones as potential modulators of vascular function in hypertension
    • Khalil R.A. Sex hormones as potential modulators of vascular function in hypertension. Hypertension 2005, 46:249-254. 10.1161/01.HYP.0000172945.06681.a4.
    • (2005) Hypertension , vol.46 , pp. 249-254
    • Khalil, R.A.1
  • 36
    • 84864582811 scopus 로고    scopus 로고
    • Sex differences in hypertension: contribution of the renin-angiotensin system
    • Maric-Bilkan C., Manigrasso M.B. Sex differences in hypertension: contribution of the renin-angiotensin system. Gend. Med. 2012, 9:287-291. 10.1016/j.genm.2012.06.005.
    • (2012) Gend. Med. , vol.9 , pp. 287-291
    • Maric-Bilkan, C.1    Manigrasso, M.B.2
  • 37
    • 84880134748 scopus 로고    scopus 로고
    • Cholesterol and atherosclerosis: modulation by oestrogen
    • Barton M. Cholesterol and atherosclerosis: modulation by oestrogen. Curr. Opin. Lipidol. 2013, 24:214-220. 10.1097/MOL.0b013e3283613a94.
    • (2013) Curr. Opin. Lipidol. , vol.24 , pp. 214-220
    • Barton, M.1
  • 38
    • 84924973471 scopus 로고    scopus 로고
    • Effects of low-dose versus placebo or conventional dose postmenopausal hormone therapy on variables related to cardiovascular risk: a systematic review and meta-analyses of randomized clinical trials
    • Casanova G., Bossardi Ramos R., Ziegelmann P., Mara Spritzer P. Effects of low-dose versus placebo or conventional dose postmenopausal hormone therapy on variables related to cardiovascular risk: a systematic review and meta-analyses of randomized clinical trials. J. Clin. Endocrinol. Metab. 2014, 100. 10.1210/jc.2014-3301.
    • (2014) J. Clin. Endocrinol. Metab. , vol.100
    • Casanova, G.1    Bossardi Ramos, R.2    Ziegelmann, P.3    Mara Spritzer, P.4
  • 40
    • 84896866847 scopus 로고    scopus 로고
    • Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study
    • Zhao J., Jiang C., Lam T.H., Liu B., Cheng K.K., Xu L., et al. Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study. Int. J. Epidemiol. 2014, 43:140-148. 10.1093/ije/dyt239.
    • (2014) Int. J. Epidemiol. , vol.43 , pp. 140-148
    • Zhao, J.1    Jiang, C.2    Lam, T.H.3    Liu, B.4    Cheng, K.K.5    Xu, L.6
  • 41
    • 84876176964 scopus 로고    scopus 로고
    • Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials
    • Xu L., Freeman G., Cowling B.J., Schooling C.M. Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials. BMC Med. 2013, 11:108. 10.1186/1741-7015-11-108.
    • (2013) BMC Med. , vol.11 , pp. 108
    • Xu, L.1    Freeman, G.2    Cowling, B.J.3    Schooling, C.M.4
  • 43
    • 0025061133 scopus 로고
    • Antithrombin III and procoagulant activity: sex differences and effects of the menopause
    • Meade T.W., Dyer S., Howarth D.J., Imeson J.D., Stirling Y. Antithrombin III and procoagulant activity: sex differences and effects of the menopause. Br. J. Haematol. 1990, 74:77-81. 10.1111/j.1365-2141.1990.tb02541.x.
    • (1990) Br. J. Haematol. , vol.74 , pp. 77-81
    • Meade, T.W.1    Dyer, S.2    Howarth, D.J.3    Imeson, J.D.4    Stirling, Y.5
  • 44
    • 0038579421 scopus 로고    scopus 로고
    • Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project
    • Conroy R.M., Pyörälä K., Fitzgerald A.P., Sans S., Menotti A., De Backer G., et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur. Heart J. 2003, 24:987-1003. 10.1016/S0195-668X(03)00114-3.
    • (2003) Eur. Heart J. , vol.24 , pp. 987-1003
    • Conroy, R.M.1    Pyörälä, K.2    Fitzgerald, A.P.3    Sans, S.4    Menotti, A.5    De Backer, G.6
  • 45
    • 39549093148 scopus 로고    scopus 로고
    • General cardiovascular risk profile for use in primary care: the Framingham Heart Study
    • D'Agostino R.B., Vasan R.S., Pencina M.J., Wolf P.A., Cobain M., Massaro J.M., et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008, 117:743-753. 10.1161/CIRCULATIONAHA.107.699579.
    • (2008) Circulation , vol.117 , pp. 743-753
    • D'Agostino, R.B.1    Vasan, R.S.2    Pencina, M.J.3    Wolf, P.A.4    Cobain, M.5    Massaro, J.M.6
  • 46
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
    • Lewington S., Clarke R., Qizilbash N., Peto R., Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002, 360:1903-1913. 10.1016/s0140-6736(03)13064-4.
    • (2002) Lancet , vol.360 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 47
    • 36549034768 scopus 로고    scopus 로고
    • Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths
    • Lewington S., Whitlock G., Clarke R., Sherliker P., Emberson J., Halsey J., et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet 2007, 370:1829-1839. 10.1016/S0140-6736(07)61778-4.
    • (2007) Lancet , vol.370 , pp. 1829-1839
    • Lewington, S.1    Whitlock, G.2    Clarke, R.3    Sherliker, P.4    Emberson, J.5    Halsey, J.6


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