Structure elucidation of uniformly 13C labeled small molecule natural products

Magnetic Resonance in Chemistry

Volumn 53, Issue 12, 2015, Pages 996-1002

  Reibarkh, Mikhail ^a   Wyche, Thomas P ^b   Saurí, Josep ^a   Bugni, Tim S ^b   Martin, Gary E ^a   Thomas Williamson, R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

13C 13C COSY and COSYLR; CT HSQC; enterocin; natural products; structure elucidation; U 13C labeled

Indexed keywords

13C-13C COSY AND COSYLR; BIO-MOLECULAR; CT-HSQC; ENTEROCIN; ISOTOPICALLY LABELED; LABELLED PROTEIN; NATURAL PRODUCTS; SMALL MOLECULES; STRUCTURE ELUCIDATION; U-13C LABELED;

PROTEINS;

BIOLOGICAL PRODUCT; BIOPOLYMER;

ALGORITHM; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; ISOTOPE LABELING; MOLECULAR WEIGHT; PROCEDURES; PROTON NUCLEAR MAGNETIC RESONANCE;

ALGORITHMS; BIOLOGICAL PRODUCTS; BIOPOLYMERS; CARBON-13 MAGNETIC RESONANCE SPECTROSCOPY; COMPUTER SIMULATION; ISOTOPE LABELING; MODELS, CHEMICAL; MOLECULAR WEIGHT; PROTON MAGNETIC RESONANCE SPECTROSCOPY;

EID: 84940983603     PISSN: 07491581     EISSN: 1097458X     Source Type: Journal    
DOI: 10.1002/mrc.4333     Document Type: Article

References (25)

1. a) W. F. Reynolds, E. P. Mazzola, Progress in the Chemistry of Organic Natural Products, (Eds:, A. D. Kinghorn, H. Faul, J. Kobayashi,), Springer International Publishing, Switzerland, 2015, 100, 223-309;
2. b) R. C. Breton, W. F. Reynolds,. Nat. Prod. Rep. 2013, 30, 501-524.
3. a) R. Petkewich,. C&EN 2007, 85 (20), 56;
4. b) L. Jarvis,. C&EN 2012, 90 (8), 30.
5. W. P. Aue, E. Bartholdi, R. R. Ernst,. J. Chem. Phys. 1976, 64, 2229-2246.
6. G. E. Martin, A. S. Zekter, VCH Publishers, Inc., New York, 1988, 59.
7. A. Bax, R. Freeman,. J. Magn. Reson. 1981, 44, 542-561.
8. G. Vuister, A. Bax,. J. Magn. Reson. 1992, 98, 428-435.
9. N. Miyairi, H. I. Sakai, T. Konomi, H. Imanaka,. J. Antibiot. 1976, 29, 227-235.
10. T. D. W. Claridge, High-Resolution NMR Techniques in Organic Chemistry, Pergamon Press, New York, 1999, pp. 229-245.
11. L. Castañar, T. Parella, Ann. Rep. NMR Spectrosc,vol. 84 (Ed:, G. A. Webb,), Elsevier, Amsterdam, 2015, 163-232.
12. R. W. Adams,. eMagRes 2014, 3, 1-15.
13. K. Zangger,. Prog. Nucl. Magn. Reson. Spectrosc. 2015, 86-87, 1-20.
14. L. Castañar, T. Parella,. Magn. Reson. Chem. 2015, 53, 399-426.
15. a) S. S. Golotvin, E. Vodopianov, B. A. Lefebvre, A. J. Williams, T. D. Spitzer,. Magn. Reson. Chem. 2006, 44, 524;
16. b) S. S. Golotvin, E. Vodopianov, R. Pol, B. A. Lefebvre, A. J. Williams, R. D. Rutkowske, T. D. Spitzer,. Magn. Reson. Chem. 2007, 45, 803-813;
17. c) M. E. Elyashberg, A. J. Williams, G. E. Martin, Prog. NMR Spectrosc, vol. 53 (Eds:, J. Feeney, L. Sutcliff,), Pergammon, Oxford, 2008, 1-104.
18. a) R. T. Williamson, A. V. Buevich, G. E. Martin,. Org. Lett. 2012, 14, 5098-5101; b), J. Sauri, T. Parella, R. T. Williamson, G. E. Martin,. Magn. Reson. Chem. 2015 in press: DOI: 10.1002/mrc4322.
19. M. Foroozandeh, P. Giraudeau, D. Jeannerat,. Magn. Reson. Chem. 2013, 51, 808-814.
20. M. Reibarkh, R. T. Williamson, G. E. Martin, W. Bermel,. J. Magn. Reson. 2013, 236, 126-133.
21. L. B. Krivdin, E. W. Della, Prog. NMR Spectrosc, vol. 23 (Eds:, J. Feeney, M. Sutcliff,), Pergammon, Oxford, 1991, 301-610.
22. V. Wray,. Prog. Nucl. Magn. Reson. Spectrosc. 1979, 13, 177-236.
23. J. L. Marshall, Carbon-Carbon and Carbon-Proton NMR Couplings: Applications to Organic Stereochemical and Conformational Analysis, VCH, Deerfield Beach, FL, 1983, pp. 65-199.
24. K. Kamieńska-Trela, Ann. Rep. NMR Spectrosc, vol. 30 (Ed:, G. A. Webb,), Academic Press, New York, 1995, 131-230.
25. G. E. Martin, M. Reibarkh, A. V. Buevich, K. A. Blinov, R. T. Williamson,. eMagRes 2014, 3, 215-234.