A phase 1 trial of preoperative partial breast radiation therapy: Patient selection, target delineation, and dose delivery

Practical Radiation Oncology

Volumn 5, Issue 5, 2015, Pages e513-e520

  Blitzblau, Rachel C ^a   Arya, Ritu ^a   Yoo, Sua ^a   Baker, Jay A ^a   Chang, Zheng ^a   Palta, Manisha ^a   Duffy, Eileen ^a   Horton, Janet K ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM PENTETATE MEGLUMINE; TUMOR MARKER;

ADULT; AGED; ARTICLE; BREAST BIOPSY; BREAST CARCINOMA; CANCER LOCALIZATION; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CUTANEOUS PARAMETERS; DIFFUSION WEIGHTED IMAGING; DOSIMETRY; FEMALE; HUMAN; HUMAN TISSUE; IMAGE GUIDED RADIOTHERAPY; IMAGE PROCESSING; IMAGING SOFTWARE; INTENSITY MODULATED RADIATION THERAPY; INTRADUCTAL CARCINOMA; INVASIVE CARCINOMA; MASTECTOMY; MEDICAL TECHNOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT SELECTION; PHASE 1 CLINICAL TRIAL; POSTOPERATIVE PERIOD; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RADIATION DOSE ESCALATION; RADIATION DOSE FRACTIONATION; RADIOTHERAPY PLANNING SYSTEM; RELIABILITY; TREATMENT PLANNING; BREAST; BREAST NEOPLASMS; CLINICAL TRIAL; MIDDLE AGED; PATHOLOGY; PROCEDURES; RADIOTHERAPY DOSAGE;

BREAST; BREAST NEOPLASMS; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED;

EID: 84940959864     PISSN: 18798500     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prro.2015.02.002     Document Type: Article

References (22)

1. Fisher B., Anderson S., Bryant J., et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 2002, 347:1233-1241.
2. Veronesi U., Cascinelli N., Mariani L., et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 2002, 347:1227-1232.
3. Perou C.M., Sorlie T., Eisen M.B., et al. Molecular portraits of human breast tumours. Nature 2000, 406:747-752.
4. Paik S., Shak S., Tang G., et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 2004, 351:2817-2826.
5. Soulos P.R., Yu J.B., Roberts K.B., et al. Assessing the impact of a cooperative group trial on breast cancer care in the medicare population. J Clin Oncol 2012, 30:1601-1607.
6. Haviland J., Agrawal R., Aird E., et al. The UK START (Standardisation of Breast Radiotherapy) Trials: 10-year follow-up results. Cancer Res 2012, 72(Suppl. 3):24.
7. Whelan T.J., Pignol J.P., Levine M.N., et al. Long-term results of hypofractionated radiation therapy for breast cancer. N Engl J Med 2010, 362:513-520.
8. Olivotto I.A., Whelan T.J., Parpia S., et al. Interim cosmetic and toxicity results from RAPID: A randomized trial of accelerated partial breast irradiation using three-dimensional conformal external beam radiation therapy. J Clin Oncol 2013, 31:4038-4045.
9. Veronesi U., Orecchia R., Maisonneuve P., et al. Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT): A randomised controlled equivalence trial. Lancet Oncol 2013, 14:1269-1277.
10. Vaidya J.S., Wenz F., Bulsara M., et al. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial. Lancet 2014, 383:603-613.
11. Hepel J.T., Tokita M., Macausland S.G., et al. Toxicity of three-dimensional conformal radiotherapy for accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys 2009, 75:1290-1296.
12. Jagsi R., Ben-David M., Moran J., et al. Adverse cosmesis in a protocol investigating IMRT with active breathing control for accelerated partial breast irradiation (APBI). Int J Radiat Oncol Biol Phys 2008, 72:S153.
13. Palta M., Yoo S., Adamson J.D., Prosnitz L.R., Horton J.K. Preoperative single fraction partial breast radiotherapy for early-stage breast cancer. Int J Radiat Oncol Biol Phys 2012, 82:37-42.
14. Iaccarino G., Pinnaro P., Landoni V., et al. Single fraction partial breast irradiation in prone position. J Exp Clin Cancer Res 2007, 26:543-552.
15. Hoppe B.S., Laser B., Kowalski A.V., et al. Acute skin toxicity following stereotactic body radiation therapy for stage I non-small-cell lung cancer: Who's at risk?. Int J Radiat Oncol Biol Phys 2008, 72:1283-1286.
16. Leonard K.L., Hepel J.T., Hiatt J.R., Dipetrillo T.A., Price L.L., Wazer D.E. The effect of dose-volume parameters and interfraction interval on cosmetic outcome and toxicity after 3-dimensional conformal accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys 2013, 85:623-629.
17. (P089) A phase III randomized trial of MRI-mapped dose-escalated salvage radiotherapy postprostatectomy: The Maps Trial-An initial dosimetric assessment. Oncology (Williston Park) 2014, 28(Suppl. 1).
18. Miwa K., Matsuo M., Ogawa S., et al. Re-irradiation of recurrent glioblastoma multiforme using 11C-methionine PET/CT/MRI image fusion for hypofractionated stereotactic radiotherapy by intensity modulated radiation therapy. Radiat Oncol 2014, 9:181.
19. Regini F., Gourtsoyianni S., Cardoso De Melo R., et al. Rectal tumour volume (GTV) delineation using T2-weighted and diffusion-weighted MRI: Implications for radiotherapy planning. Eur J Radiol 2014, 83:768-772.
20. MacFadden D., Zhang B., Brock K.K., et al. Clinical evaluation of stereotactic target localization using 3-Tesla MRI for radiosurgery planning. Int J Radiat Oncol Biol Phys 2010, 76:1472-1479.
21. Nichols E.M., Mohiuddin M., Flannery T., Dhople A.A., Yu C., Regine W.F. Comparative analysis of the post-lumpectomy target volume versus the pre-lumpectomy tumor volume for early stage breast cancer: Implications for the future. San Antonio Breast Cancer Symposium 2008, Available at: http://www.abstracts2view.com/sabcs/sessionindex.php. Accessed February 12, 2015.
22. Grimsby G.M., Gray R., Dueck A., et al. Is there concordance of invasive breast cancer pathologic tumor size with magnetic resonance imaging?. Am J Surg 2009, 198:500-504.