Crosstalk events in the estrogen signaling pathway may affect tamoxifen efficacy in breast cancer molecular subtypes

Computational Biology and Chemistry

Volumn 59, Issue , 2015, Pages 42-54

  De Anda Jáuregui, Guillermo ^a   Mejía Pedroza, Raúl A ^a   Espinal Enríquez, Jesús ^a,b   Hernández Lemus, Enrique ^a,b  

^a INSTITUTO NACIONAL DE MEDICINA GENÓMICA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Breast cancer; Estrogen signaling; Pathway crosstalk; Systems biology

Indexed keywords

CELL DEATH; CROSSTALK; DISEASES; DRUG THERAPY; GENE EXPRESSION; HORMONES; STEROID HORMONES;

BREAST CANCER; BREAST CANCER TREATMENT; MOLECULAR PATHWAYS; NEOADJUVANT THERAPY; SIGNALING PATHWAYS; STEROID RECEPTORS; SYSTEMATIC ANALYSIS; SYSTEMS BIOLOGY;

SIGNALING;

ESTROGEN; TAMOXIFEN;

ALGORITHM; APOPTOSIS; BREAST NEOPLASMS; CELL PROLIFERATION; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ALGORITHMS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; SIGNAL TRANSDUCTION; TAMOXIFEN;

EID: 84940842801     PISSN: 14769271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compbiolchem.2015.07.004     Document Type: Article

References (58)

1. A. Azad, A. Lawen, and J. Keith Prediction of signaling cross-talks contributing to acquired drug resistance in breast cancer cells by Bayesian statistical modeling BMC Syst. Biol. 9 1 2015 2
2. I. Azimi, S. Roberts-Thomson, and G. Monteith Calcium influx pathways in breast cancer: opportunities for pharmacological intervention Br. J. Pharmacol. 171 4 2014 945 960
3. K. Baca-López, M. Mayorga, A. Hidalgo-Miranda, N. Gutiérrez-Nájera, and E. Hernández-Lemus The role of master regulators in the metabolic/transcriptional coupling in breast carcinomas PLoS ONE 7 8 2012 e42678
4. S. Behjati, and M. Frank The effects of tamoxifen on immunity Curr. Med. Chem. 16 24 2009 3076
5. H.J. Burstein, S. Temin, H. Anderson, T.A. Buchholz, N.E. Davidson, K.E. Gelmon, S.H. Giordano, C.A. Hudis, D. Rowden, A.J. Solky, and et al. Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer: American Society of Clinical Oncology Clinical Practice Guideline focused update J. Clin. Oncol. 32 21 2014 2255 2269
6. S. Carascossa, P. Dudek, B. Cenni, P.-A. Briand, and D. Picard Carm1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor α by camp Genes Dev. 24 7 2010 708 719
7. F. Cardoso, A. Costa, L. Norton, E. Senkus, M. Aapro, F. André, C. Barrios, J. Bergh, L. Biganzoli, K. Blackwell, and et al. ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2) Breast 23 5 2014 489 502
8. CENETEC Secretaría de Salud, Guía de Práctica Clínica Diagnóstico y Tratamiento del Cáncer de Mama en Segundo y Tercer nivel de Atención 2009
9. Y.-F. Chen, Y.-T. Chen, W.-T. Chiu, and M.-R. Shen Remodeling of calcium signaling in tumor progression J. Biomed. Sci. 20 2013 23
10. F. Chibon Cancer gene expression signatures - the rise and fall? Eur. J. Cancer 49 8 2013 2000 2009
11. R. Clarke, M.C. Liu, K.B. Bouker, Z. Gu, R.Y. Lee, Y. Zhu, T.C. Skaar, B. Gomez, K. O'Brien, Y. Wang, and et al. Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling Oncogene 22 47 2003 7316 7339
12. R. Clarke, K. Cook, R. Hu, C. Facey, I. Tavassoly, J. Schwartz, W. Baumann, J. Tyson, J. Xuan, Y. Wang, A. Warri, and A. Shajahan Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate Cancer Res. 72 6 2012
13. K. Cook, A. Warril, D. Soto-Pantoja, P. Clarke, I. Cruz, A. Zwart, and R. Clarke Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer Clin. Cancer Res. 20 12 2014 3222 3233
14. C. Desmedt, F. Piette, S. Loi, Y. Wang, F. Lallemand, B. Haibe-Kains, G. Viale, M. Delorenzi, Y. Zhang, M.S. d'Assignies, and et al. Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series Clin. Cancer Res. 13 11 2007 3207 3214
15. A. Dhillon, S. Hagan, O. Rath, and W. Kolch Map kinase signalling pathways in cancer Oncogene 26 22 2007 3279 3290
16. M. Donato, Z. Xu, A. Tomoiaga, J.G. Granneman, R.G. MacKenzie, R. Bao, N.G. Than, P.H. Westfall, R. Romero, and S. Draghici Analysis and correction of crosstalk effects in pathway analysis Genome Res. 23 11 2013 1885 1893
17. Y. Drier, M. Sheffer, and E. Domany Pathway-based personalized analysis of cancer Proc. Natl. Acad. Sci. U. S. A. 110 16 2013 6388 6393
18. J. Espinal-Enríquez, S. Muñoz-Montero, I. Imaz-Rosshandler, A. Huerta-Verde, C. Mejía, and E. Hernández-Lemus Genome-wide expression analysis suggests a crucial role of dysregulation of matrix metalloproteinases pathway in undifferentiated thyroid carcinoma BMC Genomics 16 207 2015 10.1186/s12864-015-1372-0
19. P. Farmer, H. Bonnefoi, V. Becette, M. Tubiana-Hulin, P. Fumoleau, D. Larsimont, G. MacGrogan, J. Bergh, D. Cameron, D. Goldstein, and et al. Identification of molecular apocrine breast tumours by microarray analysis Breast Cancer Res. 7 Suppl 2 2005 2 11
20. S. Gilbert Developmental Biology 6th ed. 2000 Sinauer Associates
21. EBCTC Group, and et al. Tamoxifen for early breast cancer: an overview of the randomised trials Lancet 351 9114 1998 1451 1467
22. M. Guedj, L. Marisa, A. De Reynies, B. Orsetti, R. Schiappa, F. Bibeau, G. Macgrogan, F. Lerebours, P. Finetti, M. Longy, and et al. A refined molecular taxonomy of breast cancer Oncogene 31 9 2012 1196 1206
23. D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 1 2000 57 70
24. D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 5 2011 646 674
25. E. Hernández-Lemus Systems biology and integrative omics in breast cancer Omics Approaches in Breast Cancer 2014 Springer 333 352
26. A.V. Ivshina, J. George, O. Senko, B. Mow, T.C. Putti, J. Smeds, T. Lindahl, Y. Pawitan, P. Hall, H. Nordgren, and et al. Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer Cancer Res. 66 21 2006 10292 10301
27. P. Jia, C.-F. Kao, P.-H. Kuo, and Z. Zhao A comprehensive network and pathway analysis of candidate genes in major depressive disorder BMC Syst. Biol. 5 Suppl 3 2011 S12
28. M. Kanehisa, and S. Goto KEGG: Kyoto encyclopedia of genes and genomes Nucleic Acids Res. 28 1 2000 27 30
29. M. Kanehisa, S. Goto, Y. Sato, M. Kawashima, M. Furumichi, and M. Tanabe Data, information, knowledge and principle: back to metabolism in KEGG Nucleic Acids Res. 42 D1 2014 D199 D205
30. E.K. Kim, and E.-J. Choi Pathological roles of MAPK signaling pathways in human diseases Biochim. Biophys. Acta 1802 4 2010 396 405
31. M. Kittaneh, A.J. Montero, and S. Glück Molecular profiling for breast cancer: a comprehensive review Biomark. Cancer 5 2013 61
32. J. Knowlden, I. Hutcheson, D. Barrow, J. Gee, and R. Nicholson Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor Endocrinology 146 11 2005 4609 4618
33. E.R. Levin Integration of the extranuclear and nuclear actions of estrogen Mol. Endocrinol. 19 8 2005 1951 1959 10.1210/me.2004-0390
34. R. Liu, X. Wang, G.Y. Chen, P. Dalerba, A. Gurney, T. Hoey, G. Sherlock, J. Lewicki, K. Shedden, and M.F. Clarke The prognostic role of a gene signature from tumorigenic breast-cancer cells N. Engl. J. Med. 356 3 2007 217 226
35. W. Luo, M.S. Friedman, K. Shedden, K.D. Hankenson, and P.J. Woolf Gage: generally applicable gene set enrichment for pathway analysis BMC Bioinf. 10 1 2009 161
36. G.K. Malhotra, X. Zhao, H. Band, and V. Band Histological, molecular and functional subtypes of breast cancers Cancer Biol. Ther. 10 10 2010 955 960
37. L.D. Miller, J. Smeds, J. George, V.B. Vega, L. Vergara, A. Ploner, Y. Pawitan, P. Hall, S. Klaar, E.T. Liu, and et al. An expression signature for p53 status in human breast cancer predicts mutation status transcriptional effects and patient survival Proc. Natl. Acad. Sci. U. S. A. 102 38 2005 13550 13555
38. A.J. Minn, G.P. Gupta, P.M. Siegel, P.D. Bos, W. Shu, D.D. Giri, A. Viale, A.B. Olshen, W.L. Gerald, and J. Massagué Genes that mediate breast cancer metastasis to lung Nature 436 7050 2005 518 524
39. M. Newman Networks: An Introduction 2010 Oxford University Press
40. I.B.P. Ni, Z. Zakaria, R. Muhammad, N. Abdullah, N. Ibrahim, N.A. Emran, N.H. Abdullah, and S.N.A.S. Hussain Gene expression patterns distinguish breast carcinomas from normal breast tissues: the Malaysian context Pathol. Res. Pract. 206 4 2010 223 228
41. M. Oyama, T. Nagashima, T. Suzuki, H. Kozuka-Hata, N. Yumoto, Y. Shiraishi, K. Ikeda, Y. Kuroki, N. Gotoh, T. Ishida, and et al. Integrated quantitative analysis of the phosphoproteome and transcriptome in tamoxifen-resistant breast cancer J. Biol. Chem. 286 1 2011 818 829
42. J.S. Parker, M. Mullins, M.C. Cheang, S. Leung, D. Voduc, T. Vickery, S. Davies, C. Fauron, X. He, Z. Hu, and et al. Supervised risk predictor of breast cancer based on intrinsic subtypes J. Clin. Oncol. 27 8 2009 1160 1167
43. Y. Pawitan, J. Bjöhle, L. Amler, A.-L. Borg, S. Egyhazi, P. Hall, X. Han, L. Holmberg, F. Huang, S. Klaar, and et al. Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts Breast Cancer Res. 7 6 2005 R953
44. C.M. Perou, T. Sørlie, M.B. Eisen, M. van de Rijn, S.S. Jeffrey, C.A. Rees, J.R. Pollack, D.T. Ross, H. Johnsen, L.A. Akslen, and et al. Molecular portraits of human breast tumours Nature 406 6797 2000 747 752
45. K. Polyak Heterogeneity in breast cancer J. Clin. Invest. 121 10 2011 3786
46. T. Sørlie, C.M. Perou, R. Tibshirani, T. Aas, S. Geisler, H. Johnsen, T. Hastie, M.B. Eisen, M. van de Rijn, S.S. Jeffrey, and et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc. Natl. Acad. Sci. U. S. A. 98 19 2001 10869 10874
47. G.K. Smyth limma: linear models for microarray data Bioinformatics and Computational Biology Solutions using R and Bioconductor 2005 Springer 397 420
48. C. Sotiriou, P. Wirapati, S. Loi, A. Harris, S. Fox, J. Smeds, H. Nordgren, P. Farmer, V. Praz, B. Haibe-Kains, and et al. Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis J. Natl. Cancer Inst. 98 4 2006 262 272
49. A. Subramanian, P. Tamayo, V.K. Mootha, S. Mukherjee, B.L. Ebert, M.A. Gillette, A. Paulovich, S.L. Pomeroy, T.R. Golub, E.S. Lander, and et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc. Natl. Acad. Sci. U. S. A. 102 43 2005 15545 15550
50. M. Swami Signalling: the calcium connection Nat. Rev. Cancer 10 11 2010 738 739
51. R. Tibshirani, T. Hastie, B. Narasimhan, and G. Chu Diagnosis of multiple cancer types by shrunken centroids of gene expression Proc. Natl. Acad. Sci. U. S. A. 99 10 2002 6567 6572
52. A. Tripathi, C. King, A. de la Morenas, V.K. Perry, B. Burke, G.A. Antoine, E.F. Hirsch, M. Kavanah, J. Mendez, M. Stone, N.P. Gerry, M.E. Lenburg, and C.L. Rosenberg Gene expression abnormalities in histologically normal breast epithelium of breast cancer patients Int. J. Cancer 122 7 2008 1557 1566 10.1002/ijc.23267
53. K. Unger-Salda na, and C. Infante-Casta neda Delay of medical care for symptomatic breast cancer: a literature review Salud Publica Mex. 51 2009 s270 s285
54. A.M. VanHook Ligand-independent ER activation Sci. Signal. 3 117 2010 ec112-ec112
55. G. Viale The current state of breast cancer classification Ann. Oncol. 23 Suppl. 10 2012 207 210
56. R. Viedma-Rodrí guez, L. Baiza-Gutman, F. Salamanca-Gómez, M. Diaz-Zaragoza, G. Martí nez-Hernández, R. Ruiz Esparza-Garrido, M.A. Velázquez-Flores, and D. Arenas-Aranda Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (review) Oncol. Rep. 32 1 2014 3 15
57. J. Wang, D. Duncan, Z. Shi, and B. Zhang Web-based gene set analysis toolkit (webgestalt): update 2013 Nucleic Acids Res. 41 W1 2013 W77 W83
58. A.J. Wood, B.L. Riggs, and L.C. Hartmann Selective estrogen-receptor modulators mechanisms of action and application to clinical practice N. Engl. J. Med. 348 7 2003 618 629