Mortality after emergency surgery continues to rise after discharge in the elderly: Predictors of 1-year mortality

Journal of Trauma and Acute Care Surgery

Volumn 79, Issue 3, 2015, Pages 349-358

  Rangel, Erika L ^a   Cooper, Zara ^a   Olufajo, Olubode A ^a   Reznor, Gally ^a   Lipsitz, Stuart R ^a   Salim, Ali ^a   Kwakye, Gifty ^a   Calahan, Christopher ^b   Sarhan, Mohammad ^c   Hanna, Joseph S ^c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL   (United States)

Author keywords

elderly; Emergency surgery; mortality; risk factors

Indexed keywords

SERUM ALBUMIN;

ABDOMINAL SURGERY; ACUTE ABDOMEN; AGED; BODY MASS; CAUSE OF DEATH; CHARLSON COMORBIDITY INDEX; CLINICAL CLASSIFICATION; CLINICAL EVALUATION; COMORBIDITY; COMORBIDITY ASSESSMENT; CONFERENCE PAPER; EMERGENCY SURGERY; FEMALE; HOSPITAL DISCHARGE; HUMAN; INTRAOPERATIVE PERIOD; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PERSONAL EXPERIENCE; PHYSIOLOGICAL PROCESS; PREOPERATIVE CARE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SURGICAL MORTALITY; SURGICAL TECHNIQUE; TEACHING HOSPITAL; ABDOMEN; EMERGENCY; MORTALITY; POSTOPERATIVE COMPLICATION; PREDICTIVE VALUE; RISK FACTOR; SURGERY; SURVIVAL; VERY ELDERLY;

ABDOMEN; AGED; AGED, 80 AND OVER; COMORBIDITY; EMERGENCIES; FEMALE; HUMANS; MALE; PATIENT DISCHARGE; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL ANALYSIS;

EID: 84940833791     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000000773     Document Type: Conference Paper

References (43)

1. Arenal JJ, Benito C, Concejo MP, Ortega E. Colorectal resection and primary anastomosis in patients aged 70 and older: prospective study. Eur J Surg. 1999;165:593-597.
2. Fukuda N, Wada J, Niki M, Sugiyama Y, Mushiake H. Factors predicting mortality in emergency abdominal surgery in the elderly. World J Emerg Surg. 2012;7:12-18.
3. Duron JJ, Duron E, Dugue T, Pujol J, Muscari F, Collet D, Pessaux P, Hay JM. Factors for mortality in major digestive surgery in the elderly: a multicenter prospective study. Ann Surg. 2001;254:375-382.
4. Al-Temimi M, Griffee M, Ennis TM, Preston R, Vargo D, Overton S, Kimball E, Barton R, Raminder N. When is death inevitable after emergency laparotomy? Analysis of the American College of Surgeons National Surgical Quality Improvement Program database. J Am Coll Surg. 2012;215:503-511.
5. Alexiou C, Beggs D, Salama FD, Brackenbury ET, Morgan WE. Surgery for esophageal cancer in elderly patient: the view from Nottingham. J Thorac Cardiovasc Surg. 1998;116:545-553.
6. Latkauskas T, Rudinskaite G, Kurtinaitis J, Janciauskiene R, Tamelis A, Saladzinskas Z, Pavalkis D. The impact of age on postoperative outcomes of colorectal cancer patients undergoing surgical treatment. BMC Cancer. 2005;5:153.
7. Poon RT, Law SW, Chu KM, Brankicki FJ, Wong J. Esophagectomy for carcinoma of the esophagus in the elderly: results of current surgical management. Ann Surg. 1998;227:357-364.
8. Ackermann RJ, Vogel RL, Johnson LA, Ashley DW, Solis MM. Surgery in nonagenarians: morbidity, mortality, and functional outcome. J Fam Pract. 1995;40:129-135.
9. Bufalari A, Ferri M, Cao P, Cirocchi R, Bisacci R, Moggi L. Surgical care in octogenarians. Br J Surg. 1996;83:1783-1787.
10. Hobson SA, Sutton CD, Garcea G, Thomas WM. Prospective comparison of POSSUM and P-POSSUM with clinical assessment of mortality following emergency surgery. Acta Anaesthesiol Scand. 2007;51:94-100.
11. Neary WD, Foy C, Heather BP, Earnshaw JJ. Identifying high-risk patients undergoing urgent and emergency surgery. Ann R Coll Surg Engl. 2006;88:151-156.
12. Lawrence VA, Hazuda HP, Cornell JE, Pederson T, Bradshaw PT, Mulrow CD, Page CP. Functional independence after major abdominal surgery in the elderly. J Am Coll Surg. 2004;199:762-772.
13. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)Va metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42:377-381.
14. WHO: Global Database on BodyMass Index.Available at: http://apps.who.int/ bmi/index.jsp?introPage=intro-3.html. Accessed August 24, 2014.
15. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11:R31.
16. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-383.
17. Copeland GP, Jones D, Walters M. POSSUM: a scoring system for surgical audit. Br J Surg. 1991;78:356-360.
18. Neary WD, Prytherch D, Foy C, Heather BP, Earnshaw JJ. Comparison of different methods of risk stratification in urgent and emergent surgery. Br J Surg. 2007;94:1300-1305.
19. Pelavski AD, Lacasta A, de Miguel M, Rochera MI, Roca M. Mortality and surgical risk assessment among the extreme old undergoing emergency surgery. Am J Surg. 2013;205:58-63.
20. Goffi L, Saba V, Ghiselli R, Necozione S, Mattei A, Carle F. Preoperative APACHE II and ASA scores in patients having major general surgical operations: prognostic value and potential clinical applications. Eur J Surg. 1999;165:730-735.
21. Koc M, Yoldas O, Kilic YA, Gocmen E, Ertan T, Dizen H, Tez M. Comparison and validation of scoring systems in a cohort of patients treated for perforated peptic ulcer. Langenbecks Arch Surg. 2007;392: 581-585.
22. Al-Hamoud S, Purkayastha S, Aziz O, Smith JJ, Thompson MD, Darzi AW, Stamatakis JD, Tekkis PP. Evaluating operative risk in colorectal cancer surgery: ASA and POSSUM-based predictive models. Surg Oncol. 2004;13:83-92.
23. Runkel NS, Hinz U, Lehnert T, Buhr HJ, Herfarth C. Improved outcome after emergency surgery for cancer of the large intestine. Br J Surg. 1998; 85:1260-1265.
24. Gooiker GA, Dekker JW, Bastiaannet E, van der Geest LGM, Merkus JW, van de Velde CJ, Tollenaar RA, Liefers GJ. Risk factors for excess mortality in the first year after curative surgery for colorectal cancer. Ann Surg Oncol. 2012;19:2428-2434.
25. Revenig LM, Canter DJ, Taylor MD, Tai C, Sweeney JF, Sarmiento JM, Kooby DA, Maithel SK, Master VA, Ogan K. Too frail for surgery? Initial results of a large multidisciplinary prospective study examining preoperative variables predictive of poor surgical outcomes. J Am Coll Surg. 2013;217:665-670.
26. Kim SW, Han HS, Jung HW, Kim KI, Hwang DW, Kang SB, Kim CH. Multidimensional frailty score for the prediction of postoperative mortality risk. JAMA Surg. 2014;149:633-640.
27. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56: M146-M156.
28. Ahmed N, Mandel R, Fain MJ. Frailty: an emerging geriatric syndrome. Am J Med. 2007;120:748-753.
29. Utzolino S, Ditzel CM, Baier PK, Hopt UT, Kaffarnik MF. The obesity paradox in surgical intensive care patients with peritonitis. J Crit Care. 2014;19:887.e1-887.e5.
30. Kalantar-Zadeh K, Horwich TB, Oreopoulos A, Kovesdy CP, Younessi H, Anker SD, Morley JE. Risk factor paradox in wasting diseases. Curr Opin Clin Nutr Metab Care. 2007;10:433-442.
31. Cetin DC, Basr BA. Obesity in the elderly: more complicated than you think. Cleve Clin J Med. 2014;81:51-61.
32. Poses R, McClish D, Smith W, Bekes C, Scott W. Prediction of survival of critically ill patients by admission comorbidity. J Clin Epidemiol. 1996; 49:743-747.
33. Grendar J, Shaheen AA, Myers RP, Parker R, Vollmer CM Jr, Ball CG, Quan ML, Kaplan GG, Al-Manasra T, Dixon E. Predicting in-hospital mortality in patients undergoing complex gastrointestinal surgery: determining the optimal risk adjustment method. Arch Surg. 2012;147: 126-135.
34. D'Hoore W, Bouckaert A, Tilquin C. Practical considerations on the use of Charlson comorbidity index with administrative databases. J Clin Epidemiol. 1996;49:1429-1433.
35. Morgera S, Schneider M, Neumayer HH. Long-term outcomes after acute kidney injury. Crit Care Med 2008;36(4 Suppl):S193-S197.
36. Bagshaw SM, Mortis G, Doig CJ, Godinez-Luna T, Fick GH, Laupland KB. One-year mortality in critically ill patients by severity of kidney dysfunction: a population-based assessment. Am J Kidney Dis. 2006; 48:402-409.
37. Rong S, Hueper K, Kirsch T, Greite R, Klemann C, Mengel M, Meier M, Menne J, Leitges M, Susnik N, et al. Renal PKC epsilon deficiency attenuates acute kidney injury and ischemic allograft injury via TNF alpha dependent inhibition of apoptosis and inflammation. Am J Physiol Renal Physiol. 2014;307:F718-F726 Epub 2014 Jul 23.
38. Gentile LF, Cuenca AG, Efron PA, Amg D, McKinley BA, Moldawer LL, Moore FA. Persistent inflammation and immunosuppression: a common syndrome and a new horizon for surgical intensive care. J Trauma Acute Care Surg. 2012;72:1491-1501.
39. Gammelager H, Christiansen CF, Johansen MB, Tonnesen E, Jespersen B, Sorensen HT. One-year mortality among Danish intensive care patients with acute kidney injury: a cohort study. Crit Care. 2012;16:R124.
40. Bagshaw SM, Laupland KB, Doig CJ, Mortis G, Fick GH, Mucenski M, Godinez-Luna T, Svenson LW, Rosenal T. Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study. Crit Care. 2005;9:R700-R709.
41. Cooper ZR, Powers CL, Cobb JP. Putting the patient first: honoring advance directives prior to surgery. Ann Surg. 2012;255:424-426.
42. Finlayson E, Zhao S, Varma MG. Outcomes after rectal cancer surgery in elderly nursing home residents. Dis Colon Rectum. 2012;55(12): 1229-1235.
43. Kim KI, Park KH, Koo KH, Han JS, Kim CH. Comprehensive geriatric assessment can predict postoperative morbidity and mortality in elderly patients undergoing elective surgery. Arch Gerontol Geriatr. 2013;56: 507-512.