메뉴 건너뛰기




Volumn 52, Issue 2, 2015, Pages 846-858

Topographical Distribution of Morphological Changes in a Partial Model of Parkinson’s Disease—Effects of Nanoencapsulated Neurotrophic Factors Administration

Author keywords

6 OHDA; GDNF; Neuroregeneration; Parkinson s disease; Rostro caudal gradient; VEGF

Indexed keywords

BROXURIDINE; DESIPRAMINE; DOUBLECORTIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NANOSPHERE; OXIDOPAMINE; PARGYLINE; TYROSINE 3 MONOOXYGENASE; VASCULOTROPIN; DOUBLECORTIN PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NANOCAPSULE; NERVE PROTEIN; NEUROPEPTIDE; VASCULOTROPIN A;

EID: 84940794297     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9234-y     Document Type: Article
Times cited : (18)

References (47)
  • 1
    • 33745847479 scopus 로고    scopus 로고
    • Diagnosis and treatment of Parkinson disease: molecules to medicine
    • COI: 1:CAS:528:DC%2BD28XmvV2lt7Y%3D, PID: 16823471
    • Savitt JM, Dawson VL, Dawson TM (2006) Diagnosis and treatment of Parkinson disease: molecules to medicine. J Clin Invest 116:1744–1754
    • (2006) J Clin Invest , vol.116 , pp. 1744-1754
    • Savitt, J.M.1    Dawson, V.L.2    Dawson, T.M.3
  • 2
    • 66949117423 scopus 로고    scopus 로고
    • The scientific and clinical basis for the treatment of Parkinson’s disease
    • Olanow CW, Stern MB, Sethi K (2009) The scientific and clinical basis for the treatment of Parkinson’s disease. Neurology 72:1–136
    • (2009) Neurology , vol.72 , pp. 1-136
    • Olanow, C.W.1    Stern, M.B.2    Sethi, K.3
  • 3
    • 0030686550 scopus 로고    scopus 로고
    • Functional neuropathology in Parkinson’s disease
    • PID: 9387799
    • Gibb WR (1997) Functional neuropathology in Parkinson’s disease. Eur Neurol 38(Suppl 2):21–25
    • (1997) Eur Neurol , vol.38 , pp. 21-25
    • Gibb, W.R.1
  • 5
    • 84861234452 scopus 로고    scopus 로고
    • Testing the contributions of striatal dopamine loss to the genesis of parkinsonian signs
    • COI: 1:CAS:528:DC%2BC38Xnt12ktL8%3D, PID: 22498034
    • Franco V, Turner RS (2012) Testing the contributions of striatal dopamine loss to the genesis of parkinsonian signs. Neurobiol Dis 47:114–1125
    • (2012) Neurobiol Dis , vol.47 , pp. 114-1125
    • Franco, V.1    Turner, R.S.2
  • 6
    • 0021257363 scopus 로고
    • Neurogenesis in the rat neostriatum
    • COI: 1:STN:280:DC%2BC2cjnt12ltA%3D%3D, PID: 24873960
    • Bayer SA (1984) Neurogenesis in the rat neostriatum. Int J Dev Neurosci 2:163–175
    • (1984) Int J Dev Neurosci , vol.2 , pp. 163-175
    • Bayer, S.A.1
  • 8
    • 0030614642 scopus 로고    scopus 로고
    • Mechanism of 6-hydroxydopamine neurotoxicity
    • COI: 1:STN:280:DyaK2s7ptFKrtA%3D%3D, PID: 9120425
    • Glinka Y, Gassen M, Youdim MB (1997) Mechanism of 6-hydroxydopamine neurotoxicity. J Neural Transm Suppl 50:55–66
    • (1997) J Neural Transm Suppl , vol.50 , pp. 55-66
    • Glinka, Y.1    Gassen, M.2    Youdim, M.B.3
  • 10
    • 79952282657 scopus 로고    scopus 로고
    • Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats
    • COI: 1:CAS:528:DC%2BC3cXhtlSgur7K
    • Morera-Herreras T, Ruiz-Ortega JA, Linazasoro G, Ugedo L (2011) Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats. Psychopharmacol (Berl) 214:379–389
    • (2011) Psychopharmacol (Berl) , vol.214 , pp. 379-389
    • Morera-Herreras, T.1    Ruiz-Ortega, J.A.2    Linazasoro, G.3    Ugedo, L.4
  • 12
    • 0030725572 scopus 로고    scopus 로고
    • Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson’s disease
    • COI: 1:CAS:528:DyaK2sXnsVWjtr0%3D, PID: 9361295
    • Bjorklund A, Winkler C, Rosenblad C, Kirik D (1997) Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson’s disease. Neurobiol Dis 4:186–200
    • (1997) Neurobiol Dis , vol.4 , pp. 186-200
    • Bjorklund, A.1    Winkler, C.2    Rosenblad, C.3    Kirik, D.4
  • 13
    • 0025798573 scopus 로고
    • Sham transplantation protects against 6-hydroxydopamine-induced dopaminergic toxicity in rats: behavioral and morphological evidence
    • COI: 1:CAS:528:DyaK3MXks1KntL0%3D, PID: 1832076
    • Przedborski S, Levivier M, Kostic V, Jackson-Lewis V, Dollison A, Gash DM, Fahn S, Cadet JL (1991) Sham transplantation protects against 6-hydroxydopamine-induced dopaminergic toxicity in rats: behavioral and morphological evidence. Brain Res 550:231–238
    • (1991) Brain Res , vol.550 , pp. 231-238
    • Przedborski, S.1    Levivier, M.2    Kostic, V.3    Jackson-Lewis, V.4    Dollison, A.5    Gash, D.M.6    Fahn, S.7    Cadet, J.L.8
  • 14
    • 0027451604 scopus 로고
    • The complex nature of interactive neuroregeneration-related molecules
    • COI: 1:CAS:528:DyaK2cXivVym, PID: 7691650
    • Brodkey JA, Gates MA, Laywell ED, Steindler DA (1993) The complex nature of interactive neuroregeneration-related molecules. Exp Neurol 123:251–270
    • (1993) Exp Neurol , vol.123 , pp. 251-270
    • Brodkey, J.A.1    Gates, M.A.2    Laywell, E.D.3    Steindler, D.A.4
  • 15
    • 84876668625 scopus 로고    scopus 로고
    • Emerging roles of astrocytes in neural circuit development
    • COI: 1:CAS:528:DC%2BC3sXlvF2jsL4%3D, PID: 23595014
    • Clarke LE, Barres BA (2013) Emerging roles of astrocytes in neural circuit development. Nat Rev Neurosci 14:311–321
    • (2013) Nat Rev Neurosci , vol.14 , pp. 311-321
    • Clarke, L.E.1    Barres, B.A.2
  • 16
    • 84899980315 scopus 로고    scopus 로고
    • The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry
    • Fuller HR, Hurtado ML, Wishart TM, Gates MA (2014) The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry. Proteome Sci 28;12:20
    • (2014) Proteome Sci 28;12 , pp. 20
    • Fuller, H.R.1    Hurtado, M.L.2    Wishart, T.M.3    Gates, M.A.4
  • 18
    • 33644901275 scopus 로고    scopus 로고
    • Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin
    • COI: 1:CAS:528:DC%2BD28XhsFOmurY%3D, PID: 16449797
    • Block ML, Li G, Qin L, Wu X, Pei Z, Wang T (2006) Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin. FASEB J 20:251–258
    • (2006) FASEB J , vol.20 , pp. 251-258
    • Block, M.L.1    Li, G.2    Qin, L.3    Wu, X.4    Pei, Z.5    Wang, T.6
  • 19
    • 3042845122 scopus 로고    scopus 로고
    • In vivo characterization of somatodendritic dopamine release in the substantia nigra of 6-hydroxydopamine lesioned rats
    • COI: 1:CAS:528:DC%2BD2cXlvFKlsrc%3D, PID: 15198664
    • Sarre S, Yuan H, Jonkers N, Van Hemelrijck A, Ebinger G, Michotte Y (2004) In vivo characterization of somatodendritic dopamine release in the substantia nigra of 6-hydroxydopamine lesioned rats. J Neurochem 90:29–39
    • (2004) J Neurochem , vol.90 , pp. 29-39
    • Sarre, S.1    Yuan, H.2    Jonkers, N.3    Van Hemelrijck, A.4    Ebinger, G.5    Michotte, Y.6
  • 20
    • 1542703727 scopus 로고
    • Hyperactivity of remaining dopaminergic neurones after partial destruction of the nigro-striatal dopaminergic system in the rat
    • COI: 1:CAS:528:DyaE2cXktl2qug%3D%3D, PID: 4517903
    • Agid Y, Javoy F, Glowinski J (1973) Hyperactivity of remaining dopaminergic neurones after partial destruction of the nigro-striatal dopaminergic system in the rat. Nat New Biol 245:150–151
    • (1973) Nat New Biol , vol.245 , pp. 150-151
    • Agid, Y.1    Javoy, F.2    Glowinski, J.3
  • 21
    • 0028388598 scopus 로고
    • Early-stage Parkinson’s disease: to treat or not to treat
    • Jankovic J, Shoulson I, Weiner WJ (1994) Early-stage Parkinson’s disease: to treat or not to treat. Neurology 44(Suppl 1):4–7
    • (1994) Neurology , vol.44 , pp. 4-7
    • Jankovic, J.1    Shoulson, I.2    Weiner, W.J.3
  • 22
    • 0028848352 scopus 로고
    • Calbindin-D28k: role in determining intrinsically generated firing patterns in rat supraoptic neurones
    • COI: 1:CAS:528:DyaK2MXps1ynsL4%3D, PID: 8576851
    • Li Z, Decavel C, Hatton GI (1995) Calbindin-D28k: role in determining intrinsically generated firing patterns in rat supraoptic neurones. J Physiol 488:601–608
    • (1995) J Physiol , vol.488 , pp. 601-608
    • Li, Z.1    Decavel, C.2    Hatton, G.I.3
  • 23
    • 84879971693 scopus 로고    scopus 로고
    • Parkinson’s disease is associated with altered expression of CaV1 channels and calcium-binding proteins
    • PID: 23771339
    • Hurley MJ, Brandon B, Gentleman SM, Dexter DT (2013) Parkinson’s disease is associated with altered expression of CaV1 channels and calcium-binding proteins. Brain 136:2077–2097
    • (2013) Brain , vol.136 , pp. 2077-2097
    • Hurley, M.J.1    Brandon, B.2    Gentleman, S.M.3    Dexter, D.T.4
  • 24
    • 0025742725 scopus 로고
    • Traumatic brain injuries: structural changes
    • PID: 1940963
    • Cervós-Navarro J, Lafuente JV (1991) Traumatic brain injuries: structural changes. J Neurol Sci 103:S3–S14
    • (1991) J Neurol Sci , vol.103 , pp. 3-14
    • Cervós-Navarro, J.1    Lafuente, J.V.2
  • 25
    • 79952406815 scopus 로고    scopus 로고
    • The origins of oxidant stress in Parkinson’s disease and therapeutic strategies
    • COI: 1:CAS:528:DC%2BC3MXivVGjtrY%3D, PID: 20712409
    • Surmeier DJ, Guzman JN, Sanchez-Padilla J, Goldberg JA (2011) The origins of oxidant stress in Parkinson’s disease and therapeutic strategies. Antioxid Redox Signal 14:1289–1301
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1289-1301
    • Surmeier, D.J.1    Guzman, J.N.2    Sanchez-Padilla, J.3    Goldberg, J.A.4
  • 26
    • 0442292148 scopus 로고    scopus 로고
    • Long-term effect of intra-striatal glial cell line-derived neurotrophic factor-releasing microspheres in a partial rat model of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD2cXhtFCisbo%3D, PID: 15036631
    • Jollivet C, Aubert-Pouessel A, Clavreul A, Venier-Julienne MC, Montero-Menei CN, Benoit JP, Menei P (2004) Long-term effect of intra-striatal glial cell line-derived neurotrophic factor-releasing microspheres in a partial rat model of Parkinson’s disease. Neurosci Lett 356:207–210
    • (2004) Neurosci Lett , vol.356 , pp. 207-210
    • Jollivet, C.1    Aubert-Pouessel, A.2    Clavreul, A.3    Venier-Julienne, M.C.4    Montero-Menei, C.N.5    Benoit, J.P.6    Menei, P.7
  • 28
    • 0034097605 scopus 로고    scopus 로고
    • Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model
    • COI: 1:CAS:528:DC%2BD3cXht1Ontb8%3D, PID: 10686072
    • Rosenblad C, Kirik D, Bjorklund A (2000) Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model. Exp Neurol 161:503–516
    • (2000) Exp Neurol , vol.161 , pp. 503-516
    • Rosenblad, C.1    Kirik, D.2    Bjorklund, A.3
  • 29
    • 34248660541 scopus 로고    scopus 로고
    • Crosstalk between VEGF-A/VEGFR2 and GDNF/RET signaling pathways
    • COI: 1:CAS:528:DC%2BD2sXlsFKgt7k%3D, PID: 17490619
    • Tufro A, Teichman J, Banu N, Villegas G (2007) Crosstalk between VEGF-A/VEGFR2 and GDNF/RET signaling pathways. Biochem Biophys Res Commun 358:410–416
    • (2007) Biochem Biophys Res Commun , vol.358 , pp. 410-416
    • Tufro, A.1    Teichman, J.2    Banu, N.3    Villegas, G.4
  • 30
    • 12144291581 scopus 로고    scopus 로고
    • Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson’s disease
    • PID: 15066146
    • Yasuhara T, Shing T, Kobayashi K et al (2004) Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson’s disease. Eur J Neurosci 19:1494–1504
    • (2004) Eur J Neurosci , vol.19 , pp. 1494-1504
    • Yasuhara, T.1    Shing, T.2    Kobayashi, K.3
  • 31
    • 0037266459 scopus 로고    scopus 로고
    • Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume
    • COI: 1:STN:280:DC%2BD3s7ptlWgtg%3D%3D
    • Harrigan MR, Ennis SR, Sullivan SE, Keep RF (2003) Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume. Acta Neurochir (Wien) 145:49–53
    • (2003) Acta Neurochir (Wien) , vol.145 , pp. 49-53
    • Harrigan, M.R.1    Ennis, S.R.2    Sullivan, S.E.3    Keep, R.F.4
  • 32
    • 34249817563 scopus 로고    scopus 로고
    • Blood-brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons
    • COI: 1:CAS:528:DC%2BD2sXnvVantLk%3D, PID: 17437543
    • Rite I, Machado A, Cano J, Venero JL (2007) Blood-brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons. J Neurochem 101:1567–1582
    • (2007) J Neurochem , vol.101 , pp. 1567-1582
    • Rite, I.1    Machado, A.2    Cano, J.3    Venero, J.L.4
  • 33
    • 33646107369 scopus 로고    scopus 로고
    • VEGF receptor signalling—in control of vascular function
    • COI: 1:CAS:528:DC%2BD28XjslSktrc%3D, PID: 16633338
    • Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L (2006) VEGF receptor signalling—in control of vascular function. Nat Rev Mol Cell Biol 7:359–371
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 359-371
    • Olsson, A.K.1    Dimberg, A.2    Kreuger, J.3    Claesson-Welsh, L.4
  • 34
    • 77957928091 scopus 로고    scopus 로고
    • The yin and yang of VEGF and PEDF: multifaceted neurotrophic factors and their potential in the treatment of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BC3cXhtVCitbfI, PID: 21152280
    • Falk T, Gonzalez RT, Sherman SJ (2010) The yin and yang of VEGF and PEDF: multifaceted neurotrophic factors and their potential in the treatment of Parkinson’s disease. Int J Mol Sci 11:2875–2900
    • (2010) Int J Mol Sci , vol.11 , pp. 2875-2900
    • Falk, T.1    Gonzalez, R.T.2    Sherman, S.J.3
  • 35
    • 0028849615 scopus 로고
    • Influence of growth factors on neuronal differentiation
    • COI: 1:CAS:528:DyaK2MXpslymt74%3D, PID: 8608019
    • Birling MC, Price J (1995) Influence of growth factors on neuronal differentiation. Curr Opin Cell Biol 7:878–847
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 847-878
    • Birling, M.C.1    Price, J.2
  • 36
    • 0030867989 scopus 로고    scopus 로고
    • Abnormal cerebellar development and foliation in BDNF−/− mice reveals a role for neurotrophins in CNS patterning
    • COI: 1:CAS:528:DyaK2sXlvFens7g%3D, PID: 9292718
    • Schwartz PM, Borghesani PR, Levy RL, Pomeroy SL, Segal RA (1997) Abnormal cerebellar development and foliation in BDNF−/− mice reveals a role for neurotrophins in CNS patterning. Neuron 19:269–281
    • (1997) Neuron , vol.19 , pp. 269-281
    • Schwartz, P.M.1    Borghesani, P.R.2    Levy, R.L.3    Pomeroy, S.L.4    Segal, R.A.5
  • 38
    • 84891818861 scopus 로고    scopus 로고
    • Dysregulation of neurotrophic and haematopoietic growth factors in Alzheimer’s disease: from pathophysiology to novel treatment strategies
    • COI: 1:CAS:528:DC%2BC2cXptlyrtQ%3D%3D, PID: 24251394
    • Sopova K, Gatsiou K, Stellos K, Laske C (2014) Dysregulation of neurotrophic and haematopoietic growth factors in Alzheimer’s disease: from pathophysiology to novel treatment strategies. Curr Alzheimer Res 11:27–39
    • (2014) Curr Alzheimer Res , vol.11 , pp. 27-39
    • Sopova, K.1    Gatsiou, K.2    Stellos, K.3    Laske, C.4
  • 39
    • 84885618962 scopus 로고    scopus 로고
    • Therapeutic benefit of a combined strategy using erythropoietin and endothelial progenitor cells after transient focal cerebral ischemia in rats
    • COI: 1:CAS:528:DC%2BC3sXhs1Wms7vL, PID: 23816235
    • Pellegrini L, Bennis Y, Guillet B, Velly L, Garrigue P, Sabatier F, Dignat-George F, Bruder N, Pisano P (2013) Therapeutic benefit of a combined strategy using erythropoietin and endothelial progenitor cells after transient focal cerebral ischemia in rats. Neurol Res 35:937–947
    • (2013) Neurol Res , vol.35 , pp. 937-947
    • Pellegrini, L.1    Bennis, Y.2    Guillet, B.3    Velly, L.4    Garrigue, P.5    Sabatier, F.6    Dignat-George, F.7    Bruder, N.8    Pisano, P.9
  • 40
    • 80052392214 scopus 로고    scopus 로고
    • Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine
    • COI: 1:CAS:528:DC%2BC3MXhtFKjtLjN, PID: 21903079
    • Gittis AH, Hang GB, LaDow ES, Shoenfeld LR, Atallah BV, Finkbeiner S, Kreitzer AC (2011) Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine. Neuron 71:858–868
    • (2011) Neuron , vol.71 , pp. 858-868
    • Gittis, A.H.1    Hang, G.B.2    LaDow, E.S.3    Shoenfeld, L.R.4    Atallah, B.V.5    Finkbeiner, S.6    Kreitzer, A.C.7
  • 41
    • 0033792547 scopus 로고    scopus 로고
    • Inhibition of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum
    • COI: 1:STN:280:DC%2BD3M%2Fjtlegtg%3D%3D, PID: 11029615
    • Batchelor PE, Liberatore GT, Porritt MJ, Donnan GA, Howells DW (2000) Inhibition of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum. Eur J Neurosci 12:3462–3468
    • (2000) Eur J Neurosci , vol.12 , pp. 3462-3468
    • Batchelor, P.E.1    Liberatore, G.T.2    Porritt, M.J.3    Donnan, G.A.4    Howells, D.W.5
  • 42
    • 0021262155 scopus 로고
    • Selective histochemical demonstration of dopamine terminal systems in rat di- and telencephalon: new evidence for dopaminergic innervation of hypothalamic neurosecretory nuclei
    • COI: 1:CAS:528:DyaL2cXlt1eltb8%3D, PID: 6466973
    • Lindvall O, Björklund A, Skagerberg G (1984) Selective histochemical demonstration of dopamine terminal systems in rat di- and telencephalon: new evidence for dopaminergic innervation of hypothalamic neurosecretory nuclei. Brain Res 306:19–30
    • (1984) Brain Res , vol.306 , pp. 19-30
    • Lindvall, O.1    Björklund, A.2    Skagerberg, G.3
  • 43
    • 0036283426 scopus 로고    scopus 로고
    • Modeling Parkinson’s disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway
    • COI: 1:CAS:528:DC%2BD38XksVequr0%3D, PID: 12061862
    • Deumens R, Blokland A, Prickaerts J (2002) Modeling Parkinson’s disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway. Exp Neurol 175:303–317
    • (2002) Exp Neurol , vol.175 , pp. 303-317
    • Deumens, R.1    Blokland, A.2    Prickaerts, J.3
  • 44
    • 84891093236 scopus 로고    scopus 로고
    • Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BC2cXltFOrsA%3D%3D, PID: 24291725
    • Yue X, Hariri DJ, Caballero B, Zhang S, Bartlett MJ, Kaut O, Mount DW, Wüllner U, Sherman SJ, Falk T (2014) Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson’s disease. Neuroscience 258:385–400
    • (2014) Neuroscience , vol.258 , pp. 385-400
    • Yue, X.1    Hariri, D.J.2    Caballero, B.3    Zhang, S.4    Bartlett, M.J.5    Kaut, O.6    Mount, D.W.7    Wüllner, U.8    Sherman, S.J.9    Falk, T.10
  • 45
    • 0032939002 scopus 로고    scopus 로고
    • Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson’s disease after administration into the striatum or the lateral ventricle
    • COI: 1:STN:280:DyaK1M3jtl2ntA%3D%3D, PID: 10215908
    • Rosenblad C, Kirik D, Devaux B, Moffat B, Phillips HS, Björklund A (1999) Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson’s disease after administration into the striatum or the lateral ventricle. Eur J Neurosci 11:1554–1566
    • (1999) Eur J Neurosci , vol.11 , pp. 1554-1566
    • Rosenblad, C.1    Kirik, D.2    Devaux, B.3    Moffat, B.4    Phillips, H.S.5    Björklund, A.6
  • 46
    • 84897055332 scopus 로고    scopus 로고
    • Distribution of dopamine transporter immunoreactive fibers in the human amygdaloid complex
    • García-Amado M, Prensa L (2013) Distribution of dopamine transporter immunoreactive fibers in the human amygdaloid complex. Euro J Neurosci 38:3589–3601
    • (2013) Euro J Neurosci , vol.38 , pp. 3589-3601
    • García-Amado, M.1    Prensa, L.2
  • 47
    • 84875546097 scopus 로고    scopus 로고
    • VEGF reverts the cognitive impairment induced by a focal traumatic brain injury during the development of rats raised under environmental enrichment
    • COI: 1:CAS:528:DC%2BC3sXmsFalt74%3D, PID: 23470903
    • Ortuzar N, Rico-Barrio I, Bengoetxea H, Argandoña EG, Lafuente JV (2013) VEGF reverts the cognitive impairment induced by a focal traumatic brain injury during the development of rats raised under environmental enrichment. Behav Brain Res 246:36–46
    • (2013) Behav Brain Res , vol.246 , pp. 36-46
    • Ortuzar, N.1    Rico-Barrio, I.2    Bengoetxea, H.3    Argandoña, E.G.4    Lafuente, J.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.