메뉴 건너뛰기




Volumn 14, Issue 1, 2015, Pages

Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2

Author keywords

HCC; KLF2; Long non coding RNA; Proliferation; TUG1

Indexed keywords

KRUPPEL LIKE FACTOR 2; LONG UNTRANSLATED RNA; POLYCOMB REPRESSIVE COMPLEX 2; TAURINE UPREGULATED GENE 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; KLF2 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; TUG1 LONG NONCODING RNA, HUMAN;

EID: 84940743131     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0431-0     Document Type: Article
Times cited : (221)

References (36)
  • 1
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007;132:2557-76.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 3
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: from genes to environment
    • Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer. 2006;6:674-87.
    • (2006) Nat Rev Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    DePinho, R.A.2
  • 4
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet. 2012;379:1245-55.
    • (2012) Lancet , vol.379 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 7
    • 84921508145 scopus 로고    scopus 로고
    • MicroRNA-331-3p promotes proliferation and metastasis of hepatocellular carcinoma by targeting PH domain and leucine-rich repeat protein phosphatase
    • Chang RM, Yang H, Fang F, Xu JF, Yang LY. MicroRNA-331-3p promotes proliferation and metastasis of hepatocellular carcinoma by targeting PH domain and leucine-rich repeat protein phosphatase. Hepatology. 2014;60:1251-63.
    • (2014) Hepatology , vol.60 , pp. 1251-1263
    • Chang, R.M.1    Yang, H.2    Fang, F.3    Xu, J.F.4    Yang, L.Y.5
  • 9
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489:57-74.
    • (2012) Nature , vol.489 , pp. 57-74
  • 10
  • 11
    • 84879987789 scopus 로고    scopus 로고
    • lincRNAs: genomics, evolution, and mechanisms
    • Ulitsky I, Bartel DP. lincRNAs: genomics, evolution, and mechanisms. Cell. 2013;154:26-46.
    • (2013) Cell , vol.154 , pp. 26-46
    • Ulitsky, I.1    Bartel, D.P.2
  • 12
    • 79953858658 scopus 로고    scopus 로고
    • No-nonsense functions for long noncoding RNAs
    • Nagano T, Fraser P. No-nonsense functions for long noncoding RNAs. Cell. 2011;145:178-81.
    • (2011) Cell , vol.145 , pp. 178-181
    • Nagano, T.1    Fraser, P.2
  • 13
    • 78651390167 scopus 로고    scopus 로고
    • Long intergenic noncoding RNAs: new links in cancer progression
    • Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Res. 2011;71:3-7.
    • (2011) Cancer Res , vol.71 , pp. 3-7
    • Tsai, M.C.1    Spitale, R.C.2    Chang, H.Y.3
  • 14
    • 84867900638 scopus 로고    scopus 로고
    • Long non-coding RNAs and cancer: a new frontier of translational research?
    • Spizzo R, Almeida MI, Colombatti A, Calin GA. Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene. 2012;31:4577-87.
    • (2012) Oncogene , vol.31 , pp. 4577-4587
    • Spizzo, R.1    Almeida, M.I.2    Colombatti, A.3    Calin, G.A.4
  • 15
    • 84899157532 scopus 로고    scopus 로고
    • Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition
    • Sun M, Liu XH, Wang KM, Nie FQ, Kong R, Yang JS, et al. Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition. Mol Cancer. 2014;13:68.
    • (2014) Mol Cancer , vol.13 , pp. 68
    • Sun, M.1    Liu, X.H.2    Wang, K.M.3    Nie, F.Q.4    Kong, R.5    Yang, J.S.6    Xia, R.7    Xu, T.P.8    Jin, F.Y.9    Liu, Z.J.10
  • 16
    • 84917705634 scopus 로고    scopus 로고
    • Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer
    • Hu Y, Wang J, Qian J, Kong X, Tang J, Wang Y, et al. Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer. Cancer Res. 2014;74:6890-902.
    • (2014) Cancer Res , vol.74 , pp. 6890-6902
    • Hu, Y.1    Wang, J.2    Qian, J.3    Kong, X.4    Tang, J.5    Wang, Y.6    Chen, H.7    Hong, J.8    Zou, W.9    Chen, Y.10
  • 18
    • 15744387853 scopus 로고    scopus 로고
    • The noncoding RNA taurine up-regulated gene 1 is required for differentiation of the murine retina
    • Young TL, Matsuda T, Cepko CL. The noncoding RNA taurine up-regulated gene 1 is required for differentiation of the murine retina. Curr Biol. 2005;15:501-12.
    • (2005) Curr Biol , vol.15 , pp. 501-512
    • Young, T.L.1    Matsuda, T.2    Cepko, C.L.3
  • 19
    • 84907960468 scopus 로고    scopus 로고
    • P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression
    • Zhang EB, Yin DD, Sun M, Kong R, Liu XH, You LH, et al. P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression. Cell Death Dis. 2014;5:e1243.
    • (2014) Cell Death Dis , vol.5 , pp. e1243
    • Zhang, E.B.1    Yin, D.D.2    Sun, M.3    Kong, R.4    Liu, X.H.5    You, L.H.6    Han, L.7    Xia, R.8    Wang, K.M.9    Yang, J.S.10
  • 20
    • 84929335649 scopus 로고    scopus 로고
    • Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma
    • Xu Y, Wang J, Qiu M, Xu L, Li M, Jiang F, et al. Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma. Tumour Biol. 2014;36(3):1643-51.
    • (2014) Tumour Biol , vol.36 , Issue.3 , pp. 1643-1651
    • Xu, Y.1    Wang, J.2    Qiu, M.3    Xu, L.4    Li, M.5    Jiang, F.6    Yin, R.7    Xu, L.8
  • 21
    • 84875248673 scopus 로고    scopus 로고
    • Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder
    • Han Y, Liu Y, Gui Y, Cai Z. Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder. J Surg Oncol. 2013;107:555-9.
    • (2013) J Surg Oncol , vol.107 , pp. 555-559
    • Han, Y.1    Liu, Y.2    Gui, Y.3    Cai, Z.4
  • 22
    • 84880289686 scopus 로고    scopus 로고
    • Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis
    • Zhang Q, Geng PL, Yin P, Wang XL, Jia JP, Yao J. Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis. Asian Pac J Cancer Prev. 2013;14:2311-5.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 2311-2315
    • Zhang, Q.1    Geng, P.L.2    Yin, P.3    Wang, X.L.4    Jia, J.P.5    Yao, J.6
  • 23
    • 84930542114 scopus 로고
    • LncRNA: a link between RNA and cancer
    • Yang G, Lu X, Yuan L. LncRNA: a link between RNA and cancer. Biochim Biophys Acta. 1839;2014:1097-109.
    • (1839) Biochim Biophys Acta , vol.2014 , pp. 1097-1109
    • Yang, G.1    Lu, X.2    Yuan, L.3
  • 24
  • 25
    • 84908671045 scopus 로고    scopus 로고
    • A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer
    • Hu X, Feng Y, Zhang D, Zhao SD, Hu Z, Greshock J, et al. A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer. Cancer Cell. 2014;26:344-57.
    • (2014) Cancer Cell , vol.26 , pp. 344-357
    • Hu, X.1    Feng, Y.2    Zhang, D.3    Zhao, S.D.4    Hu, Z.5    Greshock, J.6    Zhang, Y.7    Yang, L.8    Zhong, X.9    Wang, L.P.10
  • 27
    • 84928703265 scopus 로고    scopus 로고
    • Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9-Mediated RXRA Signaling Pathway
    • Cui M, Xiao Z, Wang Y, Zheng M, Song T, Cai X, et al. Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9-Mediated RXRA Signaling Pathway. Cancer Res. 2015;75:846-57.
    • (2015) Cancer Res , vol.75 , pp. 846-857
    • Cui, M.1    Xiao, Z.2    Wang, Y.3    Zheng, M.4    Song, T.5    Cai, X.6    Sun, B.7    Ye, L.8    Zhang, X.9
  • 28
    • 84927933097 scopus 로고    scopus 로고
    • A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma
    • Tang J, Zhuo H, Zhang X, Jiang R, Ji J, Deng L, et al. A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma. Cell Death Dis. 2014;5:e1549.
    • (2014) Cell Death Dis , vol.5 , pp. e1549
    • Tang, J.1    Zhuo, H.2    Zhang, X.3    Jiang, R.4    Ji, J.5    Deng, L.6    Qian, X.7    Zhang, F.8    Sun, B.9
  • 30
    • 84947038724 scopus 로고    scopus 로고
    • SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer
    • Xu TP, Liu XX, Xia R, Yin L, Kong R, Chen WM, et al. SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer. Oncogene. 2015. doi: 10.1038/onc.2015.18 .
    • (2015) Oncogene
    • Xu, T.P.1    Liu, X.X.2    Xia, R.3    Yin, L.4    Kong, R.5    Chen, W.M.6    Huang, M.D.7    Shu, Y.Q.8
  • 31
    • 84856961647 scopus 로고    scopus 로고
    • Kruppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7
    • Ebert R, Zeck S, Meissner-Weigl J, Klotz B, Rachner TD, Benad P, et al. Kruppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells. Bone. 2012;50:723-32.
    • (2012) cells. Bone. , vol.50 , pp. 723-732
    • Ebert, R.1    Zeck, S.2    Meissner-Weigl, J.3    Klotz, B.4    Rachner, T.D.5    Benad, P.6
  • 32
    • 67349101678 scopus 로고    scopus 로고
    • Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2
    • Yamada T, Park CS, Mamonkin M, Lacorazza HD. Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2. Nat Immunol. 2009;10:618-26.
    • (2009) Nat Immunol , vol.10 , pp. 618-626
    • Yamada, T.1    Park, C.S.2    Mamonkin, M.3    Lacorazza, H.D.4
  • 33
    • 84901201313 scopus 로고    scopus 로고
    • KLF9, a transcription factor induced in flutamide-caused cell apoptosis, inhibits AKT activation and suppresses tumor growth of prostate cancer cells
    • Shen P, Sun J, Xu G, Zhang L, Yang Z, Xia S, et al. KLF9, a transcription factor induced in flutamide-caused cell apoptosis, inhibits AKT activation and suppresses tumor growth of prostate cancer cells. Prostate. 2014;74:946-58.
    • (2014) Prostate , vol.74 , pp. 946-958
    • Shen, P.1    Sun, J.2    Xu, G.3    Zhang, L.4    Yang, Z.5    Xia, S.6
  • 34
    • 79953172903 scopus 로고    scopus 로고
    • A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth
    • Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, et al. A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth. Biochem J. 2011;435:529-37.
    • (2011) Biochem J. , vol.435 , pp. 529-537
    • Fernandez-Zapico, M.E.1    Lomberk, G.A.2    Tsuji, S.3    DeMars, C.J.4    Bardsley, M.R.5    Lin, Y.H.6
  • 35
    • 84921444103 scopus 로고    scopus 로고
    • Long Noncoding RNA ANRIL Promotes Non-Small Cell Lung Cancer Cell Proliferation and Inhibits Apoptosis by Silencing KLF2 and P21 Expression
    • Nie FQ, Sun M, Yang JS, Xie M, Xu TP, Xia R, et al. Long Noncoding RNA ANRIL Promotes Non-Small Cell Lung Cancer Cell Proliferation and Inhibits Apoptosis by Silencing KLF2 and P21 Expression. Mol Cancer Ther. 2015;14:268-77.
    • (2015) Mol Cancer Ther , vol.14 , pp. 268-277
    • Nie, F.Q.1    Sun, M.2    Yang, J.S.3    Xie, M.4    Xu, T.P.5    Xia, R.6
  • 36
    • 0032879468 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: the BCLC staging classification
    • Llovet JM, Bru C, Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis. 1999;19:329-38.
    • (1999) Semin Liver Dis , vol.19 , pp. 329-338
    • Llovet, J.M.1    Bru, C.2    Bruix, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.