Viral transduction of renin rapidly establishes persistent hypertension in diverse murine strains

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 309, Issue 5, 2015, Pages R467-R474

  Harlan, Shannon M ^a   Ostroski, Robert A ^a   Coskun, Tamer ^a   Yantis, Loudon D ^a   Breyer, Matthew D ^a   Heuer, Josef G ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Adenovirus; Hypertensive murine model; Renin

Indexed keywords

RENIN;

ADENO ASSOCIATED VIRUS; ADULT; ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BACKCROSSING; BREEDING; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; EMBRYO; HEART WEIGHT; HUMAN; HUMAN CELL; HYPERTENSION; IMPLANTATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; VIRAL GENE DELIVERY SYSTEM; 129 MOUSE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CARDIOMEGALY; DBA MOUSE; DEPENDOPARVOVIRUS; DISEASE COURSE; DISEASE MODEL; GENE VECTOR; GENETIC PREDISPOSITION; GENETIC TRANSDUCTION; GENETICS; METABOLISM; MUTATION; PHENOTYPE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TIME FACTOR;

ALBUMINURIA; ANIMALS; ARTERIAL PRESSURE; CARDIOMEGALY; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENETIC PREDISPOSITION TO DISEASE; GENETIC VECTORS; HYPERTENSION; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, INBRED DBA; MUTATION; PHENOTYPE; RENIN; RENIN-ANGIOTENSIN SYSTEM; TIME FACTORS; TRANSDUCTION, GENETIC;

EID: 84940705999     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00106.2015     Document Type: Article

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